1.Growth hormone response to peripheral infusion of clonidine in patients with panic disorder, major depression and alcohol dependence(1 ).
Joo Jin KIM ; Dong Hyun AHN ; Tae Hyuk YOO
Journal of Korean Neuropsychiatric Association 1992;31(3):488-498
No abstract available.
Clonidine*
;
Depression*
;
Growth Hormone*
;
Humans
;
Panic Disorder*
;
Panic*
2.Gd-DTPA Eenhanced IVIRI of the Cerebral Venous Angiomas: Cornparision with Cerebral Angiography.
Myung Soon KIM ; Hyun Ju PARK ; Ahn Young JOO
Journal of the Korean Radiological Society 1994;30(2):207-211
PURPOSE: The purpose of this study is to evaluate the gadolinium-enhanced MR imaging findings of cerebral venous angiomas, and to compare those findings with those of cerebral angiography. MATERIALS AND METHODS: We reviewed the findings of gadolinium-enhanced MR images of 11 cases with angiographically proved cerebral venous angiomas. We obtained Tl-and T2-weighted images with gadoliniumenhanced Tl-weighted images at a 0.5 T MR imager with a spin-echo technique. We analyzed the location and signal intensity of the lesion, pattern of contrast enhancement, the distribution of draining veins and medullary veins before and after contrast enhancement, and then compared with the findings of cerebral angiography. RESULTS: The characteristic central tubular signal void structure showed low signal intensity on Tl-weighted images and high signal intensity on T2-weighted images in all cases. After gadolinium enhancement, we could find a characteristic enhancement of all medullary and central veins in 7 cases. CONCLUSION: Gadolinium-enhanced MR image was useful in the diagnosis of venous angiomas especially in the detection of medullary veins. The invasive cerebral angiography could be replaced by this technique in this disease.
Central Nervous System Venous Angioma*
;
Cerebral Angiography*
;
Diagnosis
;
Gadolinium
;
Gadolinium DTPA*
;
Hemangioma
;
Magnetic Resonance Imaging
;
Veins
3.Regulation of Astroglial Volume by Ketamine in Glutamate Induced Cellular Volume Changes.
Myung Hee KIM ; Tae Soo HAHM ; Hyun Joo AHN
Korean Journal of Anesthesiology 1997;33(6):1005-1011
BACKGROUND: Relative changes of astroglial volume constitute the major part of brain edema, which is related to delayed neuronal damage. Several factors including glutamate may contribute to astroglial swelling. Intravenous anesthetic, ketamine was known to restore neuronal damage by inhibiting NMDA receptor activity. Therefore, we decided to investigate the effect of ketamine on the astrocyte swelling by glutamate in the present study. METHODS: To analyze cell swelling in vitro, glial cell line, U1242MG was used. The effects of glutamate (1, 2, 3 mM), and glutamate with ketamine (1 mM) on the regulation of astrocyte volume were achieved by flow cytometry system. To eliminate the dead cells from experimental cell suspension and to assess cell viability, fluorescent dye propidium iodide was used. RESULTS: Glutamate addition (1, 2, 3mM) caused astroglial swelling both in calcium present and calcium absent buffer. The difference of cellular swelling dependent on glutamate concentration was only seen in calcium free buffer (p<0.05). Ketamine per se did not affect astroglial volume. However, when it was added to glutamate perfusion, 1 mM ketamine diminished cellular swelling by glutamate during first 10 minutes (p<0.05), and cellular shrinkage by glutamate after 1 hour incubation (p<0.05). CONCLUSIONS: Ketamine (1 mM) is effective in the regulation of astroglial volume alterations induced by glutamate in both short time and long time perfusion.
Astrocytes
;
Brain Edema
;
Calcium
;
Cell Survival
;
Flow Cytometry
;
Glutamic Acid*
;
Ketamine*
;
N-Methylaspartate
;
Neuroglia
;
Neurons
;
Perfusion
;
Propidium
4.The Percieved Health Status of Female Workers and It's Determinants in the Small and Medium Scaled Industries.
Jae Eog AHN ; Joo Ja KIM ; Seung Hyun HAN
Korean Journal of Epidemiology 1995;17(2):235-248
458 female workers working in the small and medium scaled industries in Inchon area were surveyed to study their general characteristics, health behavior, working and environmental conditions, current health status etc. Self-administered questionnaire was developed by authors and distributed to the female workers with the explanation by trained interviewer on the purpose of survey and the method how to answer. The results were as follows: t. General characteristics showed that most(75.3%) of workers were living in their own home, and their age distribution was relatively even from teenagers to the forties. The level of education was high school graduate(including drop-out) in 69.4%, suggesting that the education level of female workers was increasing gradually. The marrital status was 69% in unmarried, and 31% in married state. 2. Survey on their health status showed that more than 20% of female workers complained that they have some kind of disease and most of them complained that they have chronic symptoms more than three kinds. Also, they complained at least two or three symptoms in physical, mental or sensoryneural symptoms respectively. But their medical care utility rate was only 22%. 3. There were no significantly correlated variables between health status and general characteristics(by x2-test). Among the variables on the health behavior, only alcohol drinking was significant to health status. Perceived health status related to the working environment was significantly different to the degree of work satisfaction and awareness for the exposure to harzadous materials. 4. Multivariable analysis showed that work satisfaction, awareness for the exposure to harzadous materials, alcohol drinking, type of employment were significantly related to the physical or mental health index, and also marrital status was to the physical health index. Work satisfaction, awareness for the exposure to harzadous materials, marrital status were related to the sensoryneural health index. Alcohol drinking, work satisfaction, awareness for the exposure to harzadous materials, marrital status were significantly related to the number of complained chronic symptoms. In summary, this study showed that inspite of wide and various range of the general characteristics of female industrial workers in Korea comparing to the past, there was high prevalence of disease due to the poor working conditions and low work satisfaction etc. Therefore, more detailed disease preventive policies or improvement of the work environment, and systematic management to raise the work satisfaction of female workers are urgently needed. And also, occupational health policies increasing the access to health care to provide the adequate health service for the workers who have perceived need are necessary.
Adolescent
;
Age Distribution
;
Alcohol Drinking
;
Education
;
Employment
;
Female*
;
Health Behavior
;
Health Services
;
Health Services Accessibility
;
Humans
;
Incheon
;
Job Satisfaction
;
Korea
;
Mental Health
;
Occupational Health
;
Prevalence
;
Single Person
;
Surveys and Questionnaires
5.Photoelastic analysis of the Stress distribution on an intervertebral disc.
Hyun Kug SHIN ; Jae Chang LEE ; Myun Whan AHN ; Jong Chul AHN ; Joo Chul IHN
Yeungnam University Journal of Medicine 1989;6(2):223-239
To observe the change in the status of stresses according to three different postural angulation of an intervertebral disc with or without nucleus pulposus, 6 specimens of a 3-dimensional photoelastic model of the spine were made of epoxy. The nucleus pulposus portion was replaced with silicon in three models, and the three were made without silicon. Through axial application of a vertical compressive load of 8 kg, the peculiar patterns of the isochromatic fringes were observed. Stresses on the intervertebral disc were analyzed according to three different postural angulations of the intervertebral disc with the nucleus pulposus and without the nucleus pulposus. The results of these study are as follow: 1. In an erect neutral posture with the nucleus pulposus, the stress concentration was much increased at the posterior portion rather than at the anterior portion. Also, the high stress was concentrated at the medial and central portion. In an erect neutral posture without the nucleus pulposus, the stress concentration was much increased at the anterior portion rather than at the posterior portion and the stress distribution seemed to be locally concentrated. 2. In a maximal flexed posture, the stress concentration was much increased at the posterior portion rather than at the anterior portion. Comparing the presence of the nucleus pulposus with the absence of the nucleus pulposus, the stress concentration was lower at the anterior portion in the presence of the nucleus pulposus than in the absence of the nucleus pulposus. However, the stress distribution at the posterior portion was nearly same in the two groups. According to the analysis of the stress distribution diagram, as a whole, the stress pattern around the disc was evenly distributed. 3. In a maximal extended posture, the higher concentration of the stress distribution at the anterior and medial portion rather than in the posterior and lateral portion was observed. The stress concentration was higher in the presence of the nucleus pulposus than in the absence of the nucleus pulposus. 4. Comparing the maximal flexed posture with the erect neutral posture, the stress concentration in the flexed posture was much decreased in the posterior portion rather than in the erect neutral posture, and an even distribution of the stress pattern in the flexed posture was observed. 5. In the presence of the nucleus pulposus, at the anterior and posterior portion, the stress concentration in the flexed posture was much decreased compared with the extended posture. In the absence of the nucleus pulposus, at the anterior and posterior portion, the stress concentration in the extended posture was much decreased compared with the flexed posture.
Intervertebral Disc*
;
Posture
;
Silicon
;
Spine
6.Epidemiological Studies on Geriatric Hypertension in Korea.
Hae Joo KIM ; Young Ahn AHN ; Hyun II CHUN ; Jae Seong LEE ; Shin Chae HUH ; Sun Tae KIM
Korean Circulation Journal 1984;14(2):327-332
A total of 4757 apparently healthy aged persons over 65 years of age was surveyed for geriatric hypertension. A single blood pressure measurement was taken in the sitting position. Mean systolic blood pressure rose significantly with age in female but didn't in male and mean diastolic blood pressure didn't change with age in both sex. The prevalence of pure systolic hypertension, i.e., a systolic blood pressure greater than or equal to 160 mmhg and a diastolic blood pressure less than 95mmhg, increased with age. The prevalence was slighty lower for female than it was for male, being 7.0% for female and 8.0% for male. The prevalence of classical hypertension-defined as diastolic blood pressure greater than or equal to 95mmhg - was 42.7% for female and 48.2% for male and it rose with age in female. The prevalence of both pure systolic and classical hypertension was 49.7% for female and 56.1% for male.
Blood Pressure
;
Epidemiologic Studies*
;
Female
;
Humans
;
Hypertension*
;
Korea*
;
Male
;
Prevalence
7.Alterations in the stress distribution on an intervertebral disc according to postural change.
Myun Whan AHN ; Hyun Kug SHIN ; Jong Chul AHN ; Joo Chul IHN ; Jae Suk HWANG ; Jae Do KYUN
The Journal of the Korean Orthopaedic Association 1991;26(2):496-506
No abstract available.
Intervertebral Disc*
8.Treatment of bone tumors with a custom-made prosthetic replacement.
Hyun Kug SHIN ; Jae Sung SUH ; Jong Chul AHN ; Joo Chul IHN
Yeungnam University Journal of Medicine 1991;8(1):206-214
We treated three cases of bone tumors-giant cell tumor, chondroblastoma and malignant fibrous histiocytoma-with a custom-made prosthetic replacement. The patients were followed from 10 months to 18 months, postoperatively. The results of these study are as follows: 1. Satisfactory anatomic restoration 2. Early ambulation 3. Good function 4. Biomechanically sound reconstruction
Chondroblastoma
;
Early Ambulation
;
Humans
9.Clinical Studies on Risk Facotrs of Recurrnces after First Febrile Convulsions in Infancies and Early Childhood.
Hee Kyung CHUN ; Hyun Ki JOO ; Mi Soo AHN ; Ji Sub OH
Journal of the Korean Pediatric Society 1994;37(6):786-793
The aim of this study was to evaluate the risk factors of recurrences after their first febrile convulsions in infants and young children. Dlinical studies were made on 187 cases of febrile convulsions who were admitted to the Department of pediatrics of wallace Memorial Baptist Hospital from March, 1990 to December, 1992. 1) 63 cases of 187 cases had recurrences after their febrile convulsions. Thus, the recurrence rate was 33.7%. 2) The male to female ratio was 2.1:1. And there were no significant differences in recurrence rates between sexes. 3) The recurrence rate was significantly higher in those whose initial febrile convulsions were developed before first 18 months of life than those whose initial convulsions were after 18 months of age (49.5% vs. 12.5%). 4) The time interval from initial attack to recurrence was within 12 months in 80% of cases. 5) Our study revealed that the seizure characteristics of the initial febrile convulsion are not important as predictive factors about the probability of recurrences. 6) Among the total 187 cases, family history were present in 52 cases (27.8%). And there were significantly higher recurrence rates if their families show the same history of febrile convulsion (63.5% vs. 22.2%). 7) The risk of recurrence was much higher in patients whose first febrile history of febrile convulsion at the same time.
Child
;
Female
;
Humans
;
Infant
;
Male
;
Pediatrics
;
Protestantism
;
Recurrence
;
Risk Factors
;
Seizures
;
Seizures, Febrile*
10.Cognitive Behavior Therapy of Bulimia Nervosa in a Male Patient: A Case Report.
Journal of Korean Neuropsychiatric Association 1999;38(4):915-924
Bulimia nervosa is a disorder that is defined as binge eating combined with inappropriate ways of stopping weight gain. It is significantly more common in females than in males. Males in bulimia account for 10-15% of all bulimic patients. There are many methods of treatment, including drug therapy, or psychotherapy. Among them cognitive behavior therapy is reported to be the most effective method of improving the binge eating behavior and the cognitive distortion about body weight and body image. In this case, a male bulimic patient, who was hospitalized in the closed ward involuntarily, was treated with modified Fairburn's cognitive behavior therapy model. After 6 weeks of treatment, binge eating and self-induced vomiting behaviors were controlled and weight gain was nearly successful.
Body Image
;
Body Weight
;
Bulimia Nervosa*
;
Bulimia*
;
Cognitive Therapy*
;
Drug Therapy
;
Female
;
Humans
;
Male*
;
Psychotherapy
;
Vomiting
;
Weight Gain