1.Growth hormone response to peripheral infusion of clonidine in patients with panic disorder, major depression and alcohol dependence(1 ).
Joo Jin KIM ; Dong Hyun AHN ; Tae Hyuk YOO
Journal of Korean Neuropsychiatric Association 1992;31(3):488-498
No abstract available.
Clonidine*
;
Depression*
;
Growth Hormone*
;
Humans
;
Panic Disorder*
;
Panic*
2.Clinical results of surgical treatment for recurrent and habitual patellar dislocation.
Jin Hwan AHN ; Sang Gweon LEE ; Hyun Soo HAN
The Journal of the Korean Orthopaedic Association 1993;28(1):385-391
No abstract available.
Patellar Dislocation*
3.A Case of Congenital Atlanto-Occipital Fusion: One case report
Jin Hwan AHN ; Myung Chul YOU ; Suck Hyun LEE ; Bong Kun KIM ; Seung Joon AHN
The Journal of the Korean Orthopaedic Association 1977;12(3):535-538
A cases is reported of congenital atlanto-occipital fusion in a 12-years-old girl. The lesion was treated by occipito-cervical arthrodesis by iliac bone grafting with wiring. The congenital atlanto-occipital fusion has not progressed in this 2 years of observation. This is presented with a review of literature.
Arthrodesis
;
Bone Transplantation
;
Female
;
Humans
4.Operative treatment of supracondylar-Condylar Fractures of the Femur
Jin Hwan AHN ; Myung Chul YOU ; Suck Hyun LEE ; Hyun Soo KIM ; Shin Hyeok KANG
The Journal of the Korean Orthopaedic Association 1976;11(4):700-708
The previous reports about Supracondylar-Condylar Fracture of the femur which extends to articular surfaces revealed poor results in general, regardless of the methods of treatment. But those results are thought to be much alleviated if they are treated according to the principles of ASIF. Fifteen cases of Supracondylar-condylar fractures of the femur from 13 patients were treated by open reduction and rigid internal fixation during last 3 years at Department of Orthopedic Surgery, Early mobilization of knee joint was permissible in most of the cases without loss of fixation or other complications during convalescence Subsequently, greatifying results were obtained as observed in varying period of follow up days.
Convalescence
;
Early Ambulation
;
Femur
;
Follow-Up Studies
;
Humans
;
Knee Joint
;
Orthopedics
5.A case of infectious mononucleosis.
Yong Jin AHN ; Hae Youp KIM ; Hyung Jin CHUNG ; Hyun Ho SHIN ; Dong Hee CHO
Korean Journal of Infectious Diseases 1991;23(3):189-193
No abstract available.
Infectious Mononucleosis*
6.Tumor-Associated Lymphocytes Predict Response to Neoadjuvant Chemotherapy in Breast Cancer Patients.
Hee Jin LEE ; Jin Young SEO ; Jin Hee AHN ; Sei Hyun AHN ; Gyungyub GONG
Journal of Breast Cancer 2013;16(1):32-39
PURPOSE: Tumor-associated lymphocyte numbers in breast cancer have been suggested as a new independent predictor of response to neoadjuvant chemotherapy in breast cancer patients. We therefore evaluated the relationship between pathologic complete response (pCR) and tumor-associated lymphocytes in tumors of such patients. METHODS: Between 2000 and 2009, we retrospectively evaluated 175 patients with primary breast cancer treated with neoadjuvant chemotherapy, followed by definitive surgical resection. Peritumoral lymphocytic infiltration (LI) and CD3+, CD8+, and forkhead box P3 (FOXP3)+ lymphocytes were assessed in pretreatment biopsy specimens. RESULTS: Nineteen (11%) patients achieved pCR. An elevated LI, CD3+, CD8+, or FOXP3+ lymphocytic infiltration; lower clinical T stage; human epidermal growth factor receptor 2 overexpression; and herceptin-based treatment were all significantly associated with pCR. Through a multivariate analysis, LI (odds ratio [OR], 1.26; p=0.024), clinical T stage (OR, 3.06; p=0.041), and the use of a herceptin-based regimen (OR, 4.95; p=0.004) were all significant independent predictors of pCR. Significantly higher numbers of tumor-associated lymphocytes and CD3+, CD8+, and FOXP3+ T-cells were observed in the following: high-grade tumors, tumors of positive nodal status, and tumors negative for hormone receptors. CONCLUSION: Tumor-associated lymphocytes are significantly associated with pCR, suggesting that tumor-associated lymphocytes may be an important pathological factor predicting a response to neoadjuvant chemotherapy in breast cancer patients.
Biopsy
;
Breast
;
Breast Neoplasms
;
Humans
;
Lymphocyte Count
;
Lymphocytes
;
Multivariate Analysis
;
Neoadjuvant Therapy
;
Polymerase Chain Reaction
;
Receptor, Epidermal Growth Factor
;
Receptor, erbB-2
;
Retrospective Studies
;
T-Lymphocytes
7.Bronchial mucoepidermoid carcinoma: CT findings.
Hyun KIM ; Si Won KANG ; Kuk Jin AHN ; Yong Whee BAHK
Journal of the Korean Radiological Society 1991;27(2):255-258
No abstract available.
Carcinoma, Mucoepidermoid*
8.Significance of collateral vessels on the prediction of superior vena cava syndrome on CT.
Hyun Sook KIM ; Hyung Jin KIM ; Hyeng Gon LEE ; In Oak AHN ; Sung Hoon CHUNG
Journal of the Korean Radiological Society 1993;29(4):704-710
Although visible collateral vessels on computed tomography (CT) has been considered as an important finding in superior vena cava (SVC) syndrome, there is no systematical concerning correlation between the CT evidence of collateral vessels and clinical evidence of SVC syndrome. The purpose of this study is to evaluate how accurately we predict the clinical presence of SVC syndrome by the collateral vessels in patients with apparent SVC obstruction on CT. Forty-seven patients having a CT evidence of obstruction or compression of SVC and/or its major tributaries were included in this study. Lung cancer was the most common underlying disease (n=40). The enhanced CT scans were obtained through either arm vein using a combined bolus and drip-infusion technique. Analyzing the CT scans, we particularly paid attention to the site and pattern of venous compromise, presence of collateral vessels, and if present, heir location, without knowing whether symptoms and signs were present or not, and then compared them with clinical data by a thorough review of charts. To verify the frequency of visible collateral vessels in normal subjects, we also evaluated the CT scans of 50 patients without mediastinal disease and clinical SVC syndrome as a control group. On CT, collateral vessels were found in 24 patients, among whom three patients had a single collateral and 21 patients had two or more collateral channels. There were two false positive cases, in which clinically overt SVC syndrome appeared 10days and three months after CT examination respectively, and one false negative case. The presence of collateral vessels on CT, respectively, and one false negative case. The presence of collateral vessels on CT, regardless of the number and location of collateral vessels and the pattern of venous obstruction, was a good clue for predicting the presence of clinical SVC syndrome with the sensitivity and the specificity of 95.7% and 91.7%, respectively. In control group, collateral vessels were seen in three patients (6%). We conclude that the presence of collateral vessels on CT is a highly sensitive and specific sign of clinical SVC syndrome.
Arm
;
Humans
;
Lung Neoplasms
;
Mediastinal Diseases
;
Sensitivity and Specificity
;
Superior Vena Cava Syndrome*
;
Tomography, X-Ray Computed
;
Veins
;
Vena Cava, Superior*
9.Significance of collateral vessels on the prediction of superior vena cava syndrome on CT.
Hyun Sook KIM ; Hyung Jin KIM ; Hyeng Gon LEE ; In Oak AHN ; Sung Hoon CHUNG
Journal of the Korean Radiological Society 1993;29(4):704-710
Although visible collateral vessels on computed tomography (CT) has been considered as an important finding in superior vena cava (SVC) syndrome, there is no systematical concerning correlation between the CT evidence of collateral vessels and clinical evidence of SVC syndrome. The purpose of this study is to evaluate how accurately we predict the clinical presence of SVC syndrome by the collateral vessels in patients with apparent SVC obstruction on CT. Forty-seven patients having a CT evidence of obstruction or compression of SVC and/or its major tributaries were included in this study. Lung cancer was the most common underlying disease (n=40). The enhanced CT scans were obtained through either arm vein using a combined bolus and drip-infusion technique. Analyzing the CT scans, we particularly paid attention to the site and pattern of venous compromise, presence of collateral vessels, and if present, heir location, without knowing whether symptoms and signs were present or not, and then compared them with clinical data by a thorough review of charts. To verify the frequency of visible collateral vessels in normal subjects, we also evaluated the CT scans of 50 patients without mediastinal disease and clinical SVC syndrome as a control group. On CT, collateral vessels were found in 24 patients, among whom three patients had a single collateral and 21 patients had two or more collateral channels. There were two false positive cases, in which clinically overt SVC syndrome appeared 10days and three months after CT examination respectively, and one false negative case. The presence of collateral vessels on CT, respectively, and one false negative case. The presence of collateral vessels on CT, regardless of the number and location of collateral vessels and the pattern of venous obstruction, was a good clue for predicting the presence of clinical SVC syndrome with the sensitivity and the specificity of 95.7% and 91.7%, respectively. In control group, collateral vessels were seen in three patients (6%). We conclude that the presence of collateral vessels on CT is a highly sensitive and specific sign of clinical SVC syndrome.
Arm
;
Humans
;
Lung Neoplasms
;
Mediastinal Diseases
;
Sensitivity and Specificity
;
Superior Vena Cava Syndrome*
;
Tomography, X-Ray Computed
;
Veins
;
Vena Cava, Superior*
10.An Analysis of the Research on Effect of Smoking Cessation Intervention.
Journal of Korean Academy of Community Health Nursing 2008;19(3):469-479
PURPOSE: We reviewed all the articles on effect of smoking cessation intervention to find out the way of improvement of it. METHOD: 48 researches were published in Korean journals from 1980 to 2007. The research were analyzed according to: major of first author, subjects, application of theoretical framework, contents of intervention, a term of intervention, the time of evaluation on effect of interventions, research design, dependant variables, and effect of interventions. RESULTS: Research on effect of smoking cessation intervention increased rapidly in the 2000's. At this time. 72.9% of research was published. Most of research subject were students. Theoretical framework were applied in 20.8% of articles. The most common intervention was education(39.4%). The effect of combined program on outcome variable was found to be stronger than only education program. Experimental design was used in 29.2% and quasi-experimental design was adapted in 43.8% of articles. 1-6 months intervention was in 35.4%. The long term intervention more than 1month was found to be effective. Health behavior related index was measured as a dependant variable in 62.3%. CONCLUSION: Accordingly, long term program to apply to various subject is needed.
Education
;
Health Behavior
;
Humans
;
Research Design
;
Research Subjects
;
Smoking Cessation*