1.Microwave stimulated staining of bone marrow aspiration smears and plastic embedded section.
Jong Hyun YOON ; Myong Ok SHIM ; Woon Heung SONG ; Han Ik CHO ; Sang In KIM
Korean Journal of Hematology 1991;26(2):357-362
No abstract available.
Bone Marrow*
;
Microwaves*
;
Plastics*
2.A case of subacute necrotizing lymphadenitis with pancytopenia.
Kang Hyun AHN ; Chong In LEE ; Hyun Soo KIM ; Woo Ick JANG ; Young Hak SHIM ; Youn Jung CHOI ; Woo Ik YANG
Korean Journal of Hematology 1992;27(1):183-187
No abstract available.
Lymphadenitis*
;
Pancytopenia*
3.Essential thrombocythemia.
Soo Gyeong KIM ; Se Jun HONG ; Hyun Soo KIM ; Woo Ik JANG ; Young Hak SHIM ; Myeongseo KANG
Korean Journal of Hematology 1992;27(1):141-147
No abstract available.
Thrombocythemia, Essential*
4.Clinical observation of aortic dissection.
Byeong Ik JANG ; Jin Ho PARK ; Dong Ku SHIN ; Yeoung Jo KIM ; Bong Sup SHIM ; Hyun Woo LEE ; Su Hyen KIM ; Sung Sae HAN
Yeungnam University Journal of Medicine 1992;9(2):334-341
A clinical review of 34 cases of aortic dissection which were admitted to Yeungnam University hospital between March 1983 and April 1992. The results are as follows: 1. The peak incidence was in 5th, 6th decade and male to female ratio was 1.83:1. 2. The most common cause of aortic dissection was atherosclerosis and hypertension (79%). 3. The most common presenting symptom was pain (73%). but dyspnea, palpable mass, murmur, shock were also observed. 4. Abnormal electrocardiographic finding was myocardial ischemia in 6 cases, arrhythmia in 5 cases, LVH in 5 cases. 5. The X-ray findings showed abnormal aortic contour in 10 cases but normal X-ray finding was observed in 63% of DeBaKey Type III. 6. The most common diagnostic procedure was echocardiogram and abdominal Ultrasonography. 7. The mortality of all cases was 20%, operation mortality was 18% but no death of medically treatment in medical indication.
Arrhythmias, Cardiac
;
Atherosclerosis
;
Dyspnea
;
Electrocardiography
;
Female
;
Humans
;
Hypertension
;
Incidence
;
Male
;
Mortality
;
Myocardial Ischemia
;
Shock
;
Ultrasonography
5.Complete biologic response to taxane based chemotherapy confirmed by 18FFDG PET/CT and surgery in a cancer of unknown primary site.
Jun Eul HWANG ; Ju Young YOON ; Woo Kyun BAE ; Hyun Jeong SHIM ; Ik Joo CHUNG
Journal of Gynecologic Oncology 2012;23(1):65-68
Cancers of an unknown primary site are heterogenous with respect to their clinical and pathologic features. They are generally very aggressive, but specific favorable subsets have a better prognosis. For these favorable subsets, taxane based chemotherapy is very effective for a subset of woman with papillary serous peritoneal adenocarcinoma. A 52 year-old woman underwent [18F]-FDG PET/CT for routine health screening. On PET/CT, multiple hypermetabolic lymph nodes were detected in the paraaortic spaces, and there were no other hypermetabolic abnormalities. The patient was diagnosed with an unknown primary cancer that probably originated from the ovary or peritoneum, according to clinical studies and biopsy results. This was not a typical case of a favorable subset of cancer of an unknown primary site, but the tumor showed complete biologic response to taxane based chemotherapy as revealed by PET/CT, and necrotic tumor cells were confirmed by surgery.
Adenocarcinoma
;
Biopsy
;
Bridged Compounds
;
Female
;
Humans
;
Lymph Nodes
;
Mass Screening
;
Neoplasms, Unknown Primary
;
Ovary
;
Peritoneum
;
Positron-Emission Tomography
;
Prognosis
;
Taxoids
6.A case of mycoplasma pneumonia complicated with acute respiratory failure.
Byeong Ik JANG ; Hyeung Il KIM ; Sung sook KIM ; Choong Ki LEE ; Jin Hong CHUNG ; Kwan Ho LEE ; Bong Sup SHIM ; Hyun Woo LEE
Tuberculosis and Respiratory Diseases 1992;39(2):194-198
No abstract available.
Mycoplasma*
;
Pneumonia, Mycoplasma*
;
Respiratory Insufficiency*
7.Choriocarcinoma in Posterior Mediastinum: A case Report.
Soo Sung KIM ; Han Ik BAE ; Jung Ran KIM ; Young Hyun LEE ; Jae Chul SHIM ; Gyu Chun LEE
The Korean Journal of Thoracic and Cardiovascular Surgery 1997;30(4):462-466
Primary mediastinal choriocarcinoma is characteristically seen in young males presenting with the symptomes of cough, chest pale, and gynccomastia. A 33-year-old woman was admitted to the hospital because of severe dyspnea and chest pain which was aggravated rapidly 2 or 3 days ago. Posterior mcdiastinal mass measuring about 1 cm in diameter was seen in Chest P-A, left lateral view of chest, and chest CT. Serum beta-HCG level was markedly elevated up to 200,000 mIxt. Whole body CT and other studies could not find any lesion on ovary and uterus. But, a single nodule nEeasuring about 1 cm in diameter was identified in the brain CT. The tumor cells (syncytiotrophoblastic cells) from resected mass revealed positivity on i histochemical staining for beta-HCG. She was treated with EMA-CO after resection of tumor, But, 7 months later, she was readmitted and showed cerebral hemorrhage due to metastatic choriocarcinoma. She was operated again for the brain tumor, and was doing well for further 7 months.
Adult
;
Brain
;
Brain Neoplasms
;
Cerebral Hemorrhage
;
Chest Pain
;
Choriocarcinoma*
;
Cough
;
Dyspnea
;
Female
;
Humans
;
Male
;
Mediastinum*
;
Ovary
;
Pregnancy
;
Thorax
;
Tomography, X-Ray Computed
;
Uterus
8.Comparision of signal - averaged electrocardiography (SAECG) determined by flank lead system (FLS) and pyramidal lead system (PLS) in healthy young adults.
Byeong Ik JANG ; Seung Ho KANG ; Hyeung Il KIM ; Dong Gu SIN ; Young Jo KIM ; Bong Sup SHIM ; Hyun Woo LEE
Yeungnam University Journal of Medicine 1993;10(1):179-189
It has recently become possible to record electrical activity originationg from abnormally conducting myocardium from the body surface with high-gain amplification and averaging technique. These signals, which result from delayed ventricular activation(late potentials), have been recorded in patients with documented ventricular tachyarrythmia. Several electrode lead system for detecting ventricular late potential were introduced. Pyramidal electrode lead system(PLS) is useful. Also interpretation of SAECG in the young could be of value in detecting those at risk for episodic ventricular tachycardia, but suffer from a lack of data in normal young people. There was no difference between normal values, determined by FLS and PLS at high pass filtering of 25 Hz and 80 Hz, but significant, difference was found in HFLAD and RMS-40 of 40 Hz (p<0.05). These results will provide a basis for interpretations of SAECG, determined by FLS and PLS in healthy young adults with normal QRS duration. SELECTION OF SUBJECTS: For this study, normal healthy young adult volunteers (age : mean 24 years) were recruited from the medical students at Yeungnam University Hospital, Internal Medicine. Twenty fourths male and seventeenths female subjects were selected. All subjects had normal resting ECGs as judged from both the standard 12 channel lead and echocardiography, and none had a history of cardiovascular disease. All subjects were considered to be in good general physical condition. SIGNAL-AVERAGED ELECTROCARDIOGRAPHY: In order to obtain low noise recordings with a small number of averaging cycles, all subject ware asked to relax completely in the supine position. Silver/silver chloride electrodes were attached after the skin was cleaned with alcohol, to constitute classic flank lead system(FLS) and pyramidal lead system(PLS). Signals were recorded and processed using a commercially available microprocessor-augmented ECG cart(Marquette Electronics, USA) suitable for portable bedside recording.
Cardiovascular Diseases
;
Echocardiography
;
Electrocardiography*
;
Electrodes
;
Female
;
Humans
;
Internal Medicine
;
Male
;
Myocardium
;
Noise
;
Patient Selection
;
Reference Values
;
Skin
;
Students, Medical
;
Supine Position
;
Tachycardia, Ventricular
;
Volunteers
;
Young Adult*
9.Value of Coronal Reformatted Images Using Multi-detector Computed Tomography for Nodal Staging in Non Small Cell Lung Cancer Cases.
Young Sup SHIM ; Soo Jin CHOI ; Chul Hi PARK ; Jae Ik LEE ; Hyung Sik KIM ; Chul Hyun PARK
Journal of the Korean Radiological Society 2008;59(4):247-253
PURPOSE: The aim of our study was to evaluate the value of coronal reformatted images using multi-detector computed tomography (MDCT) imaging in non small cell lung cancer (NSCLC) for the determination of lymph node (LN) metastasis. MATERIALS AND METHODS: Chest CT scans using MDCT were performed in 43 patients with pathologically proven NSCLC. The images were reconstructed with a 3 mm thickness in the axial and coronal planes. The axial images were examined for LN metastasis with and without the coronal reformatted images by the consensus of two radiologists on two separate occasions. RESULTS: In total, 214 nodal groups were dissected, of which, 33 (15.4%) were pathologically proven as LN metastasis. The sensitivity of diagnosis was higher when assessing both the axial and coronal reformatted images compared to the axial images alone (51.5% vs. 33.3%), whereas the specificity and accuracy was lower when examining both the axial and coronal reformatted images (65.7% vs. 87.8% and 63.6% vs. 79.4%). Despite this, the additional coronal reformatted images provided additional anatomical information which was helpful in the assessment of accurate nodal stations and the decline of the pitfalls. CONCLUSION: The value of coronal reformatted images for the diagnosis of nodal metastasis in NSCLC may still be unclear; however, the coronal reformatted images may lend support to the axial images in being able to provide additional anatomical information.
Carcinoma, Non-Small-Cell Lung
;
Consensus
;
Humans
;
Lymph Nodes
;
Neoplasm Metastasis
;
Radiographic Image Interpretation, Computer-Assisted
;
Sensitivity and Specificity
;
Small Cell Lung Carcinoma
;
Thorax
10.Detection of Shiga Toxin-Producing Escherichia coli by in Stitu hybridization and sequence Analysis of Stx2.
Eui Chong KIM ; Dong Young LEE ; Hae Shim CHOI ; Se Ik JOO ; Jung Hee LEE ; Sang Hyun KIM ; Sung Hwan BAN
Korean Journal of Clinical Microbiology 2000;3(2):94-98
BACKGROUND: Shiga toxin-producing Escherichia coli (STEC) was found in several serotypes of E coli including 0157 serotype. Sorbitol-MacConkey agar: may be useful for the detection of E. coli 0157, but is not helpful for the detection of sorbitol-fermenting STEC other than 0157. Moreover, some strains of E. colt 0157 can ferment sorbitol. In this study, in situ hybridization using DNA probe of shiga toxin was used for the isolation of STEC from the PCR-positive stool and -Sequenbe analysis of a part of shiga toxin gene was performed. METHODS: The stool was incubated in LB broth overnight and DNA was extracted from the culture fluid. Multiplex PCR was performed with primers for stxl and stx2 genes. Specimen showed PCR-positive was incubated on MacConkey agar and colonies were blotted with nitrocellulose membrane. Digoxigenin-labelled DNA probe for shiga toxin was made by PCR and the positive colonies were detected with anti-digoxigenin-alkaline phosphatase conjugate and nitroblue tetrazolium. Agglutination test with antisera was performed for the serotying and VTEC-RPLA kit was used for the toxin production. Sequence analysis of PCR products was performed with automatic sequence analyser. RESULTS: An stxl-negative, but stx2-positive PCR was observed in a three-year-old girl, who visited Kumi Hospital on July 19, 1999 complaining of vomiting and diarrhea. The positive colonies were isolated by in situ hybridization using stx2-specific DNA probe. The titers of stxl and stx2 by VTEC-RPLA test were negative and 1:64, respectively. Agglutination for the serotyping was not observed with all of the 0 antisera. 160-nucleotide sequence of stx2 of this isolate was identical with bacteriophage 933W (GenBank X07865), except for the change (T-C) of 957th nucleotide and amino acid sequence was identical each other. CONCLUSIONS: For the sensitive detection of STEC from the stool of patients with diarrhea, multiplex PCR is recommended with stxl- and stx2-specific primers. And in situ hybridization should be performed in PCR-positive specimen for the isolation of STEC. This method may be helpful for the detection of STEC as the causative microorganisms in food-borne outbreak.
Agar
;
Agglutination
;
Agglutination Tests
;
Amino Acid Sequence
;
Bacteriophages
;
Collodion
;
Diarrhea
;
DNA
;
Escherichia coli
;
Female
;
Gyeongsangbuk-do
;
Humans
;
Immune Sera
;
In Situ Hybridization
;
Membranes
;
Multiplex Polymerase Chain Reaction
;
Nitroblue Tetrazolium
;
Polymerase Chain Reaction
;
Sequence Analysis*
;
Serotyping
;
Shiga Toxin
;
Shiga-Toxigenic Escherichia coli*
;
Sorbitol
;
Vomiting