1.Pain and Weakness on Unilateral Upper Extremity Diagnosed as Brachial Plexopathy after Herpes Zoster Infection
Junmo CHO ; Si Hyun KANG ; Kyung Mook SEO ; Don-Kyu KIM ; Du Hwan KIM ; Hyun Iee SHIN
Clinical Pain 2020;19(2):124-128
Motor paralysis is a less common neurologic complication of herpes zoster. Until now, a few cases have been reported, and most of these cases showed brachial plexopathy involving one or two segments. We report a patient with pain and weakness on upper extremity diagnosed as brachial plexopathy after herpes zoster infection. An 88-year-old female patient complained not only tingling sense, pain, and swelling on right whole arm, but also weakness on this right upper extremity. On physical examination, weakness is seen in right shoulder abductionㆍshoulder flexionㆍelbow flexionㆍelbow extensionㆍ wrist extension (grade 4), finger flexionㆍfinger abductionㆍfinger extensionㆍfinger DIP flexion (grade 3). In electrodiagnostic study and magnetic resonance imaging study, she was diagnosed as the brachial plexopathy, whole branch involved. This is the only case of post-herpetic brachial plexopathy involving whole branch in domestic.
2.Pain and Weakness on Unilateral Upper Extremity Diagnosed as Brachial Plexopathy after Herpes Zoster Infection
Junmo CHO ; Si Hyun KANG ; Kyung Mook SEO ; Don-Kyu KIM ; Du Hwan KIM ; Hyun Iee SHIN
Clinical Pain 2020;19(2):124-128
Motor paralysis is a less common neurologic complication of herpes zoster. Until now, a few cases have been reported, and most of these cases showed brachial plexopathy involving one or two segments. We report a patient with pain and weakness on upper extremity diagnosed as brachial plexopathy after herpes zoster infection. An 88-year-old female patient complained not only tingling sense, pain, and swelling on right whole arm, but also weakness on this right upper extremity. On physical examination, weakness is seen in right shoulder abductionㆍshoulder flexionㆍelbow flexionㆍelbow extensionㆍ wrist extension (grade 4), finger flexionㆍfinger abductionㆍfinger extensionㆍfinger DIP flexion (grade 3). In electrodiagnostic study and magnetic resonance imaging study, she was diagnosed as the brachial plexopathy, whole branch involved. This is the only case of post-herpetic brachial plexopathy involving whole branch in domestic.
3.Injury to the Left Sciatic and Right Common Peroneal Nerves Combined With Multifocal Rhabdomyolysis in a Survivor of the Itaewon Crowd Crush:A Case Report
Yoonhee KIM ; Kyeongil MIN ; Myung Woo PARK ; Hyun Iee SHIN ; Du Hwan KIM
Journal of Korean Medical Science 2023;38(29):e233-
We report the case of a 27-year-old survivor of the Halloween crowd crush in Itaewon, Seoul, Korea who was diagnosed with left sciatic neuropathy and right common peroneal neuropathy accompanied by multifocal rhabdomyolysis. The patient presented to the emergency room complaining of pain from her lower back to her whole lower extremities with paraparesis and paresthesia. Her blood test showed the marked elevation of creatine kinase and liver enzymes. Magnetic resonance imaging revealed multifocal signal changes in the abdominalis and pelvic girdle muscles suggestive of rhabdomyolysis. Magnetic resonance neurography demonstrated injury to the left sciatic and right peroneal nerves.Electrophysiologic studies also revealed lesions in the left sciatic and right peroneal nerves. After comprehensive rehabilitation and conservative treatment for three months, her muscle strength improved, and she could walk independently. Although several previous studies have reported peripheral neuropathy in immobilized patients, to the best of our knowledge, no case associated with a crowd crush has been reported. Therefore, we report the case of multifocal neuropathy combined with rhabdomyolysis in a victim of a crowd crush incident with good recovery.
4.Relationship Between Grip and Pinch Strength and Activities of Daily Living in Stroke Patients.
Jung Hyun BAE ; Si Hyun KANG ; Kyung Mook SEO ; Don Kyu KIM ; Hyun Iee SHIN ; Hye Eun SHIN
Annals of Rehabilitation Medicine 2015;39(5):752-762
OBJECTIVE: To investigate the relationship between grip and pinch strength and independence in activities of daily living (ADL) in stroke patients. METHODS: Medical records of 577 stroke patients from January 2010 to February 2013 were retrospectively reviewed. Patients' grip and pinch strength of both hemiplegic and non-hemiplegic hands and the Korean version of Modified Barthel Index (K-MBI) score were collected. These patients were divided into three groups: group A (onset duration: < or =3 months), group B (onset duration: >3 months and <2 years), and group C (onset duration: > or =2 years). The correlation between grip and pinch strength and the K-MBI score was analyzed. RESULTS: In group A (95 patients), the K-MBI score was significantly (p<0.05) correlated with the grip and pinch strength of both hands in patients with right hemiplegia. Significant (p<0.05) correlation between the K-MBI score and the grip and pinch strength of the hemiplegic hand was shown in patients with left hemiplegia. In group B (69 patients) and group C (73 patients), the K-MBI score was significantly (p<0.05) correlated with the grip and pinch strength of the hemiplegic hand. CONCLUSION: Stroke patients in subacute stage mainly performed activities of daily living using their dominant hand. However, independence in ADL was associated with the strength of the affected dominant hand. For stroke patients in chronic and late chronic stages, their hand power of the affected hand was associated with independence in ADL regardless whether the dominant hand was affected.
Activities of Daily Living*
;
Functional Laterality
;
Hand
;
Hand Strength*
;
Hemiplegia
;
Humans
;
Medical Records
;
Pinch Strength*
;
Retrospective Studies
;
Stroke*
5.Relation Between Respiratory Muscle Strength and Skeletal Muscle Mass and Hand Grip Strength in the Healthy Elderly.
Hyun iee SHIN ; Don Kyu KIM ; Kyung Mook SEO ; Si Hyun KANG ; Sang Yoon LEE ; Sunhan SON
Annals of Rehabilitation Medicine 2017;41(4):686-692
OBJECTIVE: To evaluate sarcopenic indices in relation to respiratory muscle strength (RMS) in elderly people. METHODS: This study included 65 volunteers over the age of 60 (30 men and 35 women). The skeletal muscle mass index (SMI) was measured using bioimpedance analysis. Limb muscle function was assessed by handgrip strength (HGS), the Short Physical Performance Battery (SPPB), and gait speed. RMS was addressed by maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) using a spirometer. The relationships between RMS and other sarcopenic indices were investigated using the Pearson correlation coefficients and multiple regression analysis adjusted for age, HGS, and SPPB. RESULTS: Both MIP and MEP were positively correlated with SMI (r=0.451 and r=0.388, respectively, p<0.05 in both). HGS showed a significant correlation with both MIP and MEP (r=0.560, p<0.01 and r=0.393, p<0.05, respectively). There was no significant correlation between gait speed and either MIP or MEP. The SPPB was positively correlated with MEP (r=0.436, p<0.05). In the multiple regression analysis, MIP was significantly associated with HGS and SMI (p<0.001 and p<0.05, respectively), while MEP was related only with HGS (p<0.05). CONCLUSION: This study suggests that respiratory muscles, especially inspiratory muscles, are significantly related to limb muscle strength and skeletal muscle mass. The clinical significance of MIP and MEP should be further investigated with prospective studies.
Aged*
;
Extremities
;
Gait
;
Hand Strength*
;
Hand*
;
Humans
;
Male
;
Muscle Strength
;
Muscle, Skeletal*
;
Muscles
;
Prospective Studies
;
Respiratory Muscles*
;
Sarcopenia
;
Spirometry
;
Volunteers
6.Combination chemotherapy with cyclophosphamide, vincristine, procarbazine, prednisolone(C-MOPP) in Hodgkin's disease.
Kyung Hae JUNG ; Dong Bok SHIN ; Hyun Ah KIM ; Young Iee PARK ; Tae You KIM ; Keun Chil PARK ; Yoon Koo KANG ; Dae Seog HEO ; Yung Jue BANG ; Noe Kyeong KIM
Journal of the Korean Cancer Association 1991;23(4):806-813
No abstract available.
Cyclophosphamide*
;
Drug Therapy, Combination*
;
Hodgkin Disease*
;
Procarbazine*
;
Vincristine*
7.A Phase II Study of Paclitaxel and Cisplatin Combination Chemotherapy in Advanced Non-small-cell Lung Cancer.
Jung Ae LEE ; Keun Seok LEE ; Jin Seok AHN ; Jae Ho BYUN ; Hun Ho SONG ; Dae Young ZANG ; Young Iee PARK ; Young Suk PARK ; Eun Kyung MO ; Dong Kyu KIM ; Myung Goo LEE ; In Gyu HYUN ; Ki Suck JUNG ; Soo Mee BANG ; Gye Young PARK ; Jeong Woong PARK ; Eun Kyung CHO ; Seong Hwan JEONG ; Dong Bok SHIN ; Jae Hoon LEE
Cancer Research and Treatment 2003;35(3):239-244
PURPOSE: Paclitaxel and cisplatin, active drugs in the treatment of non-small-cell lung cancer (NSCLC), have been found to be synergistic and less myelotoxic in combination when the paclitaxel is given 24 hr prior to the cisplatin. Their antitumor activity and toxicity in patients with advanced NSCLC has been evaluated herein. MATERIALS AND METHODS: Seventy-four chemonaive patients, with advanced NSCLC, were enrolled. Paclitaxel, 175 mg/m2, was administered on day 1, followed 24 hr later by cisplatin, 75 mg/m2, on day 2. RESULTS: The overall response rate, median time to progression and median survival time were 51%, 7.1 months (95% confidence interval (CI), 5.5~8.7 months) and 13.7 months (95% CI, 11.3~16.1 months), respectively. There were significant differences in the overall survival rates in relation to stage and the ECOG performance status(PS). The toxicity was mainly nonhematological. Grade > or =3 neuropathy occurred in 2 (3%) patients, myalgia in 3 (4%), and bone pain in 3 (4%). The hematological toxicity was mild, and no grade 3 or 4 neutropenia was observed. CONCLUSION: The combination of paclitaxel and cisplatin is an effective and tolerable treatment regimen for advanced NSCLC during first line chemotherapy. The main toxicity was nonhematological, such as peripheral neuropathy, myalgia and bone pain, whereas the hematological toxicity itself was mild.
Cisplatin*
;
Drug Therapy
;
Drug Therapy, Combination*
;
Humans
;
Lung Neoplasms*
;
Lung*
;
Myalgia
;
Neutropenia
;
Paclitaxel*
;
Peripheral Nervous System Diseases
;
Survival Rate