2.Two Cases of Chloromethylisothiazolinone and Methylisothiazolinone-associated Toxic Lung Injury.
Eun LEE ; Seung Kook SON ; Jisun YOON ; Hyun Ju CHO ; Song I YANG ; Sungsu JUNG ; Kyung Hyun DO ; Young Ah CHO ; So Yeon LEE ; Dong Uk PARK ; Soo Jong HONG
Journal of Korean Medical Science 2018;33(16):e119-
Previous animal studies have not conclusively determined the association between exposure to humidifier disinfectants (HDs) containing 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT) and/or 2-methyl-4-isothiazolin-3-one (MIT) and development of HD-associated lung injuries. Nonetheless, patients exposed to HDs containing only CMIT and/or MIT showed clinically similar lung injuries to those exposed to HDs containing polyhexamethylene guanidine (PHMG) or oligo (2-[2-ethoxy]ethoxyethyl) guanidinium chloride (PGH). Here, we report twin sisters with lung injuries associated with exposure to CMIT/MIT-containing HDs. At 6 months of age, a younger twin sister presented with the 3-day history of cough, sputum, and respiratory difficulty. Chest radiography revealed multiple patchy consolidation and ground-glass opacities with pneumothorax and pneumomediastinum. Thoracostomy was performed due to pneumothorax at admission and she was discharged at 11 days of hospitalization. At 5 years of age, multiple tiny nodules and faint centrilobular ground-glass opacities were observed with the small pneumatocele. The elder sister visited a tertiary hospital due to dyspnea at 12 months of age. Chest radiography showed consolidation, pneumomediastinum, and pulmonary interstitial emphysema. There was no response to the administration of immunosuppressant drugs and antifibrotic agents. At 5 years of age, chest CT revealed ground-glass opacity and multiple tiny centrilobular ground-glass opacities nodules in both lungs with exercise intolerance.
Animals
;
Cough
;
Disinfectants
;
Dyspnea
;
Emphysema
;
Guanidine
;
Hospitalization
;
Humans
;
Humidifiers
;
Lung Injury*
;
Lung*
;
Mediastinal Emphysema
;
Pneumothorax
;
Radiography
;
Siblings
;
Sputum
;
Tertiary Care Centers
;
Thoracostomy
;
Thorax
;
Tomography, X-Ray Computed
;
Twins
3.A Case of Post-total hysterectomy with bilat. salpingooophorectomy Retroperitoneal Endometrial Stromal Sarcoma.
Sung Wook KIM ; Soon Ho CHOI ; Sang Ki LEE ; Jong Jin LEE ; Min Jung KIM ; Tae Young KIM ; Kyung Don BAIK ; Hyun I SON
Korean Journal of Obstetrics and Gynecology 2006;49(8):1803-1808
Endometrial stromal sarcoma (ESS) is a relatively rare form of uterine sarcoma. Endometrial stromal sarcoma (ESS) of the myometrium compose just 0.2% of uterine malignant tumors. Low-grade stromal sarcoma has extended beyond the uterus in 40% of cases at the time of diagnosis, but the extra-uterine spread is confined to the pelvis in two thirds of the cases. A few cases of extra-uterine endometrial stromal sarcoma have been reported in literature concerning the ovary and pelvis. We have experienced a Post-total hysterectomy with bilateral salpingooophorectomy retroperitoneal endometrial stromal sarcoma, so we report this case with a brief review of literature.
Animals
;
Diagnosis
;
Female
;
Hysterectomy*
;
Mice
;
Myometrium
;
Ovary
;
Pelvis
;
Sarcoma
;
Sarcoma, Endometrial Stromal*
;
Uterus
4.Solid and Papillary Epithelial Neoplasm of the Pancreas in a Child: A case Report.
Chang Won JEON ; Chang Seok OH ; Yun Soo YANG ; Chang Rock CHOI ; Young Taek LEE ; Jong Sool IHM ; Hyun I SON
Journal of the Korean Association of Pediatric Surgeons 2005;11(1):46-52
Solid and papillary epithelial neoplasm (SPEN) of the pancreas is a rare tumor with low malignant potentiality that usually occurs in young females. Preoperative evaluation, especially radiologic tests, including ultrasonography and CT scan, is helpful in the diagnosis. These studies demonstrate a well-demarcated large mass with solid and cystic portions, frequently in the tail or body of the pancreas. Complete resection is usually curative, however local invasion and/or metastasis may occur. The authors report a case of a solid and papillary epithelial neoplasm of the pancreatic body in a 14-year old child at St. Benedict Hospital and review the literature.
Adolescent
;
Child*
;
Diagnosis
;
Female
;
Humans
;
Neoplasm Metastasis
;
Neoplasms, Glandular and Epithelial*
;
Pancreas*
;
Tomography, X-Ray Computed
;
Ultrasonography
5.Elastofibroma.
Ki Hong KIM ; Jae Wook SEOL ; Yong Jik LEE ; Young Tag LEE ; Chang Rock CHOI ; Hyun I SON ; Jong Sool IHM
Journal of the Korean Surgical Society 2004;67(5):437-440
An elastofibroma, which is a rare soft tissue tumor, was excised from the left subscapular region of a 82-year-old woman. An elastofibroma is a slow-growing, pseudotumoral lesion of the soft tissues of the chest wall with peculiar radiological (CT, MR) and ultrasonographic images, and histological patterns. All cases need to undergo a biopsy in order to rule out a sarcoma. An elastofibroma is a benign tumor. If left untreated, it can grow to a considerable size and become symptomatic. Therefore it needs to be closely observed and its nature confirmed by a biopsy. This condition is rarely encountered in Korea. However, more patients could be diagnosed if more careful attention to elastofibroma is paid.
Aged, 80 and over
;
Biopsy
;
Female
;
Humans
;
Korea
;
Sarcoma
;
Thoracic Wall
6.A Case of Congenital Intramural Cyst of Uterus.
Nam Hee LEE ; Won Suk CHOI ; Sung Wook KIM ; Sun Ho CHOI ; Min Jung KIM ; Tae Young KIM ; Kyung Don BAIK ; Hyun I SON
Korean Journal of Obstetrics and Gynecology 2005;48(12):3013-3016
I experienced a case of a congenital intramural cyst of the uterine fundus. It was composed of a single layer of non-ciliated low cuboidal epithelium without associated with endometrial stroma and was found to be derived from the mesonephric duct. This case is presented with a brief review of the literature.
Epithelium
;
Uterus*
;
Wolffian Ducts
7.A Case of Carcinoid Tumor and Low Grade Mucinous Adenocarcinoma Arising in Ovarian Mature Cystic Teratoma.
Min Jung KIM ; Nam Hee LEE ; Weon Suk CHOI ; Sung Wook KIM ; Tae Young KIM ; Myung Do KIL ; Kyeong Don BAIK ; Hyun I SON
Korean Journal of Obstetrics and Gynecology 2003;46(9):1776-1780
Mature cystic teratoma of the ovary is the most common ovarian germ cell tumor and benign, but malignant transformation occurs in less than 2% of benign mature teratoma. Of the malignancies arising in teratomas, squamous cell carcinoma is the most common, however, carcinoid tumors or adenocarcinomas arising in mature cystic teratoma are uncommon, especially simultaneously. We present an unusual case of premenopausal woman having carcinoid tumor and mucinous adenocarcinoma simultaneously arising in ovarian muture cystic teratoma.
Adenocarcinoma
;
Adenocarcinoma, Mucinous*
;
Carcinoid Tumor*
;
Carcinoma, Squamous Cell
;
Female
;
Humans
;
Mucins*
;
Neoplasms, Germ Cell and Embryonal
;
Ovary
;
Teratoma*
8.Succinate-treated macrophages attenuate dextran sodium sulfate colitis in mice
I Seul PARK ; Mijeong SON ; Hyun Woo MA ; Jihyung KIM ; Da Hye KIM ; Seung Won KIM ; Jae Hee CHEON
Intestinal Research 2021;19(3):349-353
The safety and effectiveness of adalimumab was demonstrated in a phase 3 trial in Japanese patients with intestinal Behçet’s disease. The aim of this study was to evaluate the long-term safety and effectiveness of adalimumab in Japanese patients with intestinal Behçet’s disease.
9.Succinate-treated macrophages attenuate dextran sodium sulfate colitis in mice
I Seul PARK ; Mijeong SON ; Hyun Woo MA ; Jihyung KIM ; Da Hye KIM ; Seung Won KIM ; Jae Hee CHEON
Intestinal Research 2021;19(3):349-353
The safety and effectiveness of adalimumab was demonstrated in a phase 3 trial in Japanese patients with intestinal Behçet’s disease. The aim of this study was to evaluate the long-term safety and effectiveness of adalimumab in Japanese patients with intestinal Behçet’s disease.