1.Detection of the Proliferation of Muscle Fibers During Limb Lengthening by Monoclonal Antibody to Bromodeoxyuridine
Hui Wan PARK ; Kyu Hyun YANG ; Dong Min KANG
The Journal of the Korean Orthopaedic Association 1996;31(2):265-269
Soft tissue related complications are quite frequent in limb lengthening. Muscle fibers may proliferate or regenerate after stretching injury over 10-20% of their original length. However, the cells which are engaged in this phenomenon are not confirmed yet. We chased the S-phase cells (phase for DNA replication) in the posterior leg muscle during limb lengthening by immunohistochemical technique. We lengthened the tibiae of fifteen New Zealand white rabbits. We divided them into three groups and each group is consisted of five rabbits. In group 1, we lengthened the left tibiae by 10% of their original length, in Group 2, 20%, and in group, 3, 25%, respectively, At the end of lengthening posterior muscles of lengthened left side and of controlled right side were fixed and processed for Immunohistochemical staining which could detect the incorporation of bromodeoxyuridine(BDU). Labelling index(LI:% of positively stained S-phase nuclei) of group 1 was zero. LI of groups for more than 20% lengthening (sum of group 2 and 3) was statistically significant. In conclusion, nuclei around or within the muscle tissue are in S-phase during limb lengthening which means proliferation of the muscle fivers or of the certain cells that abut muscle fibers.
Bromodeoxyuridine
;
DNA
;
Extremities
;
Immunohistochemistry
;
Leg
;
Muscles
;
Rabbits
;
Tibia
2.A Clinical Study on Osteoprosis and Back Pain
Jun Seop JAHNG ; Koon Soon KANG ; Kyu Hyun YANG ; Hui Wan PARK ; Seok Beom LEE
The Journal of the Korean Orthopaedic Association 1989;24(4):1210-1216
The back pain is increasingly becoming a major problem in the elderly people. The cause of back pain in the elderly patient is quite different from in the young subject. And relationship of the occurrence of osteoporosis with the incidence of fractures in general is currently regarded as a major factor. The authors performed clinical observation on 194 elderly patients who were treated for back pain during 5 years period from April, 1983 to April, 1988 at the Department of Orthopaedic Surgery, Severance Hospital and relationship between osteoporosis and compression fracture of spine was reviewed. The results were as follows : l. Among the 194 cases of back pain(28.3% of total admission cases), whose age were over 50: 142 cases were female and 52 cases were male, being more common in female. 2. Most common cause of back pain was the compression fracture of spine : 86 cases(44.3 %). Osteoporosis was associated with 66 cases(76.7%) out of 86 cases. 3. The number of compression fracture in same patient was more frequent in osteoporotic patient and thoracolumber junction (T12, Ll) was the major site of fracture (45.6%). Compression fracture of spine caused by osteoporosis occured at multiple level in 60.6%. 4. Twenty three cases(34.8%) of compression fracture of spine with osteoporosis were found to have previous history of fractures of spine and/or extremities by radiological examination. Regarding this results, compression fractures of spine was not infrequent cause of back pain in the elderly. It was thought that re-fracture of spine should be prevented by vigorous approach against osteoporosis along with the treatment of presenting fracture in these patients.
Aged
;
Back Pain
;
Clinical Study
;
Extremities
;
Female
;
Fractures, Compression
;
Humans
;
Incidence
;
Male
;
Osteoporosis
;
Spine
3.The Limited Experiences in the Management of the Difficult Fractures of Tibia Using the Ilizarov External Fixator
Hui Wan PARK ; Jun Seop JAHNG ; Koon Soon KANG ; Kyu Hyun YANG ; Seok Beom LEE
The Journal of the Korean Orthopaedic Association 1989;24(6):1732-1738
Since 1952, Ilizarov external fixator has been developed and used for more than 30 years in Russia and world-wide interest on it has been prevalent during last 2-3 years. The fixation of the tension applied thin wires to the metal frame resist flexional and translational deformity just like other extenal fixators. But, it allows cyclic axial micro-motion at the fracture site without loss of reduction so that it can provide good environment for the fracture healing biologically and biomechanically. Another advantage of Ilizarov external fixator is that it permits mobilization of the adjacent joints and weight bearing of the fractured limb during the application of it and shortens the duration of administration. Since 1988, We applied the Ilizarov external fixator for the treatment of diffcult tibial fractures (open comminuted, segmented and comminuted fractures, nonunion, maunion) and obtained good results in 7 cases. So we report our results even if we had limited cases and experiences.
Congenital Abnormalities
;
External Fixators
;
Extremities
;
Fracture Healing
;
Fractures, Comminuted
;
Joints
;
Russia
;
Tibia
;
Tibial Fractures
;
Weight-Bearing
4.Fracture Dislocation of the interphalangeal Joint of Great Toe: Report of Three Cases
Jun Seop JAHNG ; Hui Wan PARK ; Kyu Hyun YANG ; Kang Soo CHANG
The Journal of the Korean Orthopaedic Association 1994;29(5):1424-1427
We experienced two cases of irreducible fracture dislocation and one case of neglected dislocation of the interphalangeal joint of great toe. The cause of irreducibility of fracture dislocation were an interposition of the flexor hallucis longus tendon entrapped within undisplaced longitudinal fracture of the condyle of proximal phalanx and an entrapment of the osteochondral fragment which was avulsed from the distal insertion of lateral collateral ligament.
Dislocations
;
Joints
;
Lateral Ligament, Ankle
;
Tendons
;
Toes
5.The role of the hamstrings as antagonists of quaadriceps inmaintaining knee joint stability.
Koon Soon KANG ; Jun Seop JAHNG ; Jae Ho MOON ; Hui Wan PARK ; Kyu Hyun YANG ; Byung You JANG
The Journal of the Korean Orthopaedic Association 1991;26(3):945-949
No abstract available.
Knee Joint*
;
Knee*
6.Long-term Clinical Course of Korean Patients Diagnosed with Macular Telangiectasia Type 2
Kyung Hae KANG ; Ji Hyun YOON ; Jong Woo KIM ; Chul Gu KIM ; Jae Hui KIM
Journal of the Korean Ophthalmological Society 2021;62(8):1098-1104
Purpose:
To evaluate long-term visual prognosis and changes in the retinal microstructure in patients with macular telangiectasia type 2.
Methods:
Retrospective analysis of medical records were performed for 61 eyes (32 patients) diagnosed with macular telangiectasia type 2. The visual acuity at diagnosis was compared with that at the final visit. In addition, cases were classified into three grades based on optical coherence tomography (OCT) findings: grade 1, inner retinal cavities only; grade 2, outer retinal cavities with ellipsoid zone disruption; and grade 3, ellipsoid zone disruption with proliferation of retinal pigment epithelium. Change in the grade during the follow-up was verified. In addition, visual acuities were compared between eyes with and without a change in grade.
Results:
The mean follow-up period was 41.5 ± 33.2 months. Visual acuity had deteriorated significantly from the mean logarithm of the minimal angle of resolution 0.23 ± 0.26 at diagnosis to a mean of 0.31 ± 0.31 at the final visit (p < 0.001). When classified using OCT, 65.6%, 22.9%, and 11.5% were grades 1, 2, and 3, respectively, at diagnosis and 47.5%, 36.1%, and 16.4% at the final visit. Progression of grade was noted in 22.9%. A higher degree of visual deterioration was noted in eyes showing progression than in eyes without (p = 0.002).
Conclusions
During the long-term follow-up period, visual deterioration was noted in patients with macular telangiectasia type 2. However, the degree of deterioration was not high. Progression in the disruption of the retinal microstructure was the likely cause of visual deterioration.
7.Long-term Clinical Course of Korean Patients Diagnosed with Macular Telangiectasia Type 2
Kyung Hae KANG ; Ji Hyun YOON ; Jong Woo KIM ; Chul Gu KIM ; Jae Hui KIM
Journal of the Korean Ophthalmological Society 2021;62(8):1098-1104
Purpose:
To evaluate long-term visual prognosis and changes in the retinal microstructure in patients with macular telangiectasia type 2.
Methods:
Retrospective analysis of medical records were performed for 61 eyes (32 patients) diagnosed with macular telangiectasia type 2. The visual acuity at diagnosis was compared with that at the final visit. In addition, cases were classified into three grades based on optical coherence tomography (OCT) findings: grade 1, inner retinal cavities only; grade 2, outer retinal cavities with ellipsoid zone disruption; and grade 3, ellipsoid zone disruption with proliferation of retinal pigment epithelium. Change in the grade during the follow-up was verified. In addition, visual acuities were compared between eyes with and without a change in grade.
Results:
The mean follow-up period was 41.5 ± 33.2 months. Visual acuity had deteriorated significantly from the mean logarithm of the minimal angle of resolution 0.23 ± 0.26 at diagnosis to a mean of 0.31 ± 0.31 at the final visit (p < 0.001). When classified using OCT, 65.6%, 22.9%, and 11.5% were grades 1, 2, and 3, respectively, at diagnosis and 47.5%, 36.1%, and 16.4% at the final visit. Progression of grade was noted in 22.9%. A higher degree of visual deterioration was noted in eyes showing progression than in eyes without (p = 0.002).
Conclusions
During the long-term follow-up period, visual deterioration was noted in patients with macular telangiectasia type 2. However, the degree of deterioration was not high. Progression in the disruption of the retinal microstructure was the likely cause of visual deterioration.
8.Hyperbaric oxygen therapy for decompression sickness: five-year experience in a single center
Joyng Hyun LEE ; Sang Ku JUNG ; You Jin LEE ; Se Hyun OH ; Hui Dong KANG
Journal of the Korean Society of Emergency Medicine 2022;33(6):589-598
Objective:
Hyperbaric oxygen therapy (HBOT) is the most crucial treatment for decompression sickness (DCS), which needs to be administered as swiftly as possible. This study evaluates the therapeutic responses of DCS patients and analyzes the major factors for clinical outcomes.
Methods:
This is a retrospective cohort single-center study on patients who arrived at our hospital’s emergency department for diving-related symptoms and were diagnosed with DCS and administered HBOT.
Results:
Totally, 337 patients were enrolled from June 2015 to May 2020. The proportion of SCUBA diving, rapid ascent, and inter-facility transport cases was higher in the recreational group, with a longer lag time from symptom onset to HBOT. The professional group had a higher proportion of cases with previous DCS history, total diving time, bottom time, in-water decompression, and repetitive diving. Examination of treatment outcomes revealed more type I cases and a shorter lag time from symptom onset to HBOT in the complete recovery group. Conversely, the incomplete recovery group had a higher proportion of type II cases and aggravation of symptoms before HBOT was administered.
Conclusion
DCS can occur regardless of professional or recreational divers. Both groups showed a similar level of severity. It is recommended that recreational divers should be cautious of accidents related to safety (such as rapid ascent) and receive swift treatment in case of the onset of symptoms. Occupational divers need more active efforts to get HBOT rather than just performing in-water recompression or home O2 therapy.
9.Spontaneous Rupture of Mediastinal Teratoma.
Hui Dong KANG ; Boo Soo LEE ; Jong Uk KIM ; Gil Hyun KANG ; Dae Sick RYUI ; Se Hyun OH
Journal of the Korean Society of Emergency Medicine 2009;20(2):231-234
Mediastinal teratoma is a rare mediastinal tumor. Patients with mediastinal teratoma are usually asymptomatic and are diagnosed incidentally with chest radiography or CT, but they may develop symptoms via a rupture into adjacent structures, which results in chemical pneumonia, massive hemoptysis, hemothorax, pericardial effusion, or respiratory distress. We report a case of a ruptured teratoma in a 31-year-old female presenting with cough and brown-colored sputum. Chest radiography and computed tomography of the chest showed an inhomogenous anterior mediastinal mass with fat and fluid component. It was successfully treated by surgical resection. Although mature teratomas are rare, we should be familiar with the unique CT features of a ruptured teratoma to make sure of a correct diagnosis.
Adult
;
Cough
;
Female
;
Hemoptysis
;
Hemothorax
;
Humans
;
Mediastinum
;
Pericardial Effusion
;
Pneumonia
;
Rupture
;
Rupture, Spontaneous
;
Sputum
;
Teratoma
;
Thorax
10.Discrepancies in general surgery medical terminology between South and North Korea.
Keunyoung HUR ; Do Eon PARK ; Heung Kwon OH ; Hyun Hui YANG ; Dayoung KO ; Min Hyun KIM ; Myung Jo KIM ; Sung Il KANG ; Duck Woo KIM ; Sung Bum KANG
Korean Journal of Medical Education 2018;30(1):51-56
PURPOSE: The purpose of this study was to categorize surgery-related medical terminologies used in South and North Korea and to compare and analyze discrepancies observed in the terms. METHODS: This study collected medical terminology used in the North Korean medical book “Surgery” and compared it to medical terminology found in the medical glossary of South Korea. The order of the subtitle was described according to the Instruction to Authors. RESULTS: In total, there were 2,168 individual medical terms, of which only 1,004 words (46.3%) were identical to South Korean medical terms. There were 581 similar terms (26.8%), 265 different terms (12.2%), and 318 terms that are nonexistent in South Korea (14.7%). CONCLUSION: Less than half of the medical terms used in North Korea match those used in South Korea. It is expected that the prolongation of the current division of South and North Korea will only worsen this discrepancy. Further efforts to bridge the gap through academic exchange between South Korea and North Korea are required in preparation for an era of reunification.
Democratic People's Republic of Korea*
;
Korea
;
Republic of Korea