1.The biochemical study of the serum in toxemia of pregnancy.
Woo Hyun CHANG ; Seun Kyung LEE ; Chu Yeop HUH ; Byung Hee SUH ; Jae Hyun LEE
Korean Journal of Perinatology 1991;2(2):93-101
No abstract available.
Pre-Eclampsia*
;
Toxemia*
2.Clinical study on acute pylonephritis during pregnancy and puerperium.
Hae Sung CHO ; Seun Kyung LEE ; Chu Yeop HUH ; Byung Hee SUH ; Jae Hyun LEE
Korean Journal of Perinatology 1991;2(1):48-57
No abstract available.
Postpartum Period*
;
Pregnancy*
3.Magnetic resonance imaging of abdominal disease
Byung Ihn CHOI ; In Wook CHOO ; Kyeong Hee KIM ; Man Chung HAN ; Chu Wan KIM ; Hyun Wook PARK ; Zang Hee CHO
Journal of the Korean Radiological Society 1986;22(6):1015-1026
Magnetic Resonance Imaging(MRI) with 2.0 Tesla superconductive magnet developed by Korea Advanced Institute ofScience was performed in 25 patients with various abdominal diseases and compared with x-ray CT. MRI was obtainedwith spin echo technique using a variety of pulse sequence and various slice orientation including axial, sgittaland coronal section in order to evaluate the diagnostic value, limitation and to determine the optimal pulsesequency in various abdominal diseases. MRI demonstrated the capability of detecting the lesions shown on CT inall cases and also detected one case of diffuse hepatocellular carcinoma which was not seen on CT. MRI showedcapability of differentiation of various liver mass including hepatocellular carcinoma, hemangnioma and simplecyst. MRI showed better anatomical resolution of tumor in retroperitoneum and pelvis, however CT delineatedalimentary tract disease better than MRI did.
Carcinoma, Hepatocellular
;
Humans
;
Korea
;
Liver
;
Magnetic Resonance Imaging
;
Pelvis
4.A case of lipoleiomyoma in uterus.
Hyun Tai SHIN ; Hee Suk JUNG ; Jin Kee HONG ; Chu Yeop HUH ; Seung Bo KIM ; Jae Hyun LEE
Korean Journal of Obstetrics and Gynecology 1993;36(5):711-714
No abstract available.
Uterus*
5.Treatment of carotid-carvenous fistula and internal carotid aneurysm with Latex detachable balloons
Kee Hyun CHANG ; Man Chung HAM ; Chu wan KIM ; Dae Hee HAN ; Kil Soo CHOI ; Bo Sung SIM
Journal of the Korean Radiological Society 1984;20(1):78-84
It has been widely accepted that the detachable balloon catheter technique is the treatement of choice in thecarotid-cavernous fistula and in the unclippable giant aneurysm at the cavernous or petrous portion of theinternal carotid artery. The authors successfully treated one case of the carotid-carvernous fistula and one caseof giant aneurys, located in petrous portion of the internal carotid artery using Debrun's latex datachableballoon catheter technique. In thecase with carotid-cavernous fistula, the only fistula was occluded with adetachable balloon, presserving the intrenal carotid artery. In the aneurysm case, both internal carotid arteryand aneurysm itself were completely occluded with 3 latex detachable balloons. Both patients have nocomplications. The authors will describe and discuss the Debrun's latex detachable balloon catheter technique.
Aneurysm
;
Carotid Arteries
;
Carotid Artery, Internal
;
Catheters
;
Fistula
;
Humans
;
Latex
6.Differentially Expressed Gene Profile of Acanthamoeba castellanii Induced by an Endosymbiont Legionella pneumophila
Eun-Kyung MOON ; So-Min PARK ; Ki-Back CHU ; Fu-Shi QUAN ; Hyun-Hee KONG
The Korean Journal of Parasitology 2021;59(1):67-75
Legionella pneumophila is an opportunistic pathogen that survives and proliferates within protists such as Acanthamoeba spp. in environment. However, intracellular pathogenic endosymbiosis and its implications within Acanthamoeba spp. remain poorly understood. In this study, RNA sequencing analysis was used to investigate transcriptional changes in A. castellanii in response to L. pneumophila infection. Based on RNA sequencing data, we identified 1,211 upregulated genes and 1,131 downregulated genes in A. castellanii infected with L. pneumophila for 12 hr. After 24 hr, 1,321 upregulated genes and 1,379 downregulated genes were identified. Gene ontology (GO) analysis revealed that L. pneumophila endosymbiosis enhanced hydrolase activity, catalytic activity, and DNA binding while reducing oxidoreductase activity in the molecular function (MF) domain. In particular, multiple genes associated with the GO term ‘integral component of membrane’ were downregulated during endosymbiosis. The endosymbiont also induced differential expression of various methyltransferases and acetyltransferases in A. castellanii. Findings herein are may significantly contribute to understanding endosymbiosis of L. pneumophila within A. castellanii.
7.Magnetic Resonance Imaging in Neurologic Diseases
Kee Hyun CHANG ; Man Chung HAN ; Chu Wan KIM ; Hojin MYUNG ; Kil Soo CHOI ; Chang Beom AHN ; Chang Hyun OH ; Zang Hee CHO
Journal of the Korean Radiological Society 1985;21(1):17-30
Magrjetic resonance (MR) imagings with 0.15 Tesla resistive magnet developed by Korea Advanced Institute of 5cience were performed in 27 patients with various neurologic diseases and compared with X-ray computed tomography (CT). The purpose óf the paper is to evaluate the image quality, the diagnostic value and limitation, and the optimal pulse sequence of MR imagings with a resistive magnet. The MR images were obtained by using a variety of pulse sequence with spin echo technique includïng saturation recovery, T2-weighted spin echo, and/or inversion recovery with various pulse repetition(TR) and echo delay (TE) times. The M R imaging demonstrated the capability of detecting the lesions shown on CT in all cases and also detected an additional finding in one case (multiple sclerosis) which was not seen on CT. The MR imaging appeared to be more useful than CT in the evaluation of syringomyelia of spinal cord and white matter disease, while it failed to demonstrate small calcific lesion or inflammatory nodule (less than 1 cm) shown on CT and has shown somewhat poor contrast resolution in the case of meningioma. The spatial resolution of saturation recovery images was similar or superior to CT, whereas the contrast resolution of saturation recovery was inferior to CT. While the saturation recovery images have shown false negative findings in 5 patients (19%), the inversion recovery and T2-weighted spin echo have shown consistently positive findings. The inversion recovery and T2-weighted spin echo images demonstrated better contrast discrimination between normal and pathologic conditions than the saturation recovery images, but somewhat poorer spatial resolution. Authors suggest that the MR images of both the saturation recovery with 300/30 and T2-weighted spin echo with 1000/90 be used as a routine procedure and additional iversion recovery of 1300/300/30 sequence as a option if white matter disease is suspected.
Discrimination (Psychology)
;
Humans
;
Korea
;
Leukoencephalopathies
;
Magnetic Resonance Imaging
;
Meningioma
;
Spinal Cord
;
Syringomyelia
;
Tomography, X-Ray Computed
8.beta-catenin activated hepatocellular adenoma.
Clinical and Molecular Hepatology 2013;19(2):185-189
9.A Case of Streptococcal Toxic Shock Syndrome with Myonecrosis.
Jin Kyoung CHO ; Moon Hyun CHUNG ; Kwan Hee LEE ; Young Chae CHU ; Eui Chong KIM
Korean Journal of Infectious Diseases 2000;32(6):456-461
Invasive infections by group A streptococci have reemerged as a global public health problem since the middle of the 1980s. Streptococcal toxic shock syndrome (StrepTSS) is one manifestation of invasive streptococcal infections, and it is characterized by necrotic infection of soft tissue. Myonecrosis can occur in StrepTSS, but the clinical features of this subset of StrepTSS are not clearly defined. A previously healthy 38-year-old woman was hospitalized because of pain and edema of both legs, which had developed one day prior to admission. Six hours after admission, the swelling of the patient's left leg became more severe and areas of well-demarcated violescent discoloration of the skin and hemorrhagic bullae developed. A further ten hours later, she was in shock and exhibited signs of disseminated intravascular coagulation and multiple organ failure. Gram stain of an aspirate from the bulla revealed short chains of gram-positive cocci. Streptococcus pyogenes was isolated from blood culture and the presence of streptococcal exotoxins (speA gene) and M-protein type 3 were confirmed using the polymerase chain reaction. Muscle biopsy showed extensive myonecrosis and hemorrhage without infiltration of leukocytes. Despite intensive treatment with antibiotics (including clindamycin), debridement, and intravenous gamma globulin, the patient died four days after admission to the hospital.
Adult
;
Anti-Bacterial Agents
;
Biopsy
;
Debridement
;
Disseminated Intravascular Coagulation
;
Edema
;
Exotoxins
;
Female
;
gamma-Globulins
;
Gram-Positive Cocci
;
Hemorrhage
;
Humans
;
Leg
;
Leukocytes
;
Multiple Organ Failure
;
Polymerase Chain Reaction
;
Public Health
;
Shock
;
Shock, Septic*
;
Skin
;
Streptococcal Infections
;
Streptococcus
;
Streptococcus pyogenes
10.Abdominal Fibromatosis in a Young Child: A Case Study and Review of the Literature.
Hyun Hee CHU ; Pyoung Han HWANG ; Yeon Jun JEONG ; Myoung Ja CHUNG
Korean Journal of Pathology 2013;47(5):472-476
Fibromatoses comprise many different entities of well-differentiated fibroblastic proliferation with variable collagen production and form a firm nodular mass. Abdominal fibromatosis is distinguishable from other forms of fibromatosis because of its location and its tendency to occur in women of childbearing age during or following pregnancy. Abdominal fibromatosis in children is an extremely rare condition. A 15-month-old boy presented with an abdominal wall mass that had recently increased in size. Mass excision was perfomed. The tumor was 4.3x4.1 cm and partly circumscribed. Histologically, the tumor was composed of parallel long fascicles of spindle-cells with a uniform appearance. The edges of the resected mass were infiltrative, and the surgical margins were positive. Mitotic figures were <1/10 high power fields. No cellular atypia or necrosis was present. The tumor cells were positive for vimentin and nuclear beta-catenin staining.
Abdominal Wall
;
beta Catenin
;
Child*
;
Collagen
;
Female
;
Fibroblasts
;
Fibroma
;
Fibromatosis, Abdominal*
;
Humans
;
Infant
;
Necrosis
;
Pregnancy
;
Vimentin