No abstract available.
Osteoma

Aplasia cutis congenita is a rare disorder characterized by localized or generalized absence of skin at birth. The various hypothesis and classification are proposed. Type V in Frieden's classification, which is associated with fetus papyraceus or placental infarcts, occurs as a large cutaneous defect on the trunk and extremities. We experienced the patient had skin defect affecting the lower abdomen symmetrically, with no family history of the any disorders or chromosomal anomalies and associated anomalies. A twin fetus was died in utero. We report a case of aplasia cutis congenita associated with fetus papyraceus with the review of the associated literatures.
Abdomen ; Classification ; Ectodermal Dysplasia* ; Extremities ; Fetus ; Humans ; Parturition ; Skin ; Twins

OBJECTIVE: Musical hallucinosis is uncommon symptom in the province of neuropsychiatry. Musical hallucinosis is often accompanied with hearing impairment caused by physical illness and is characterized by no psychotic symptoms. In the previous study, musical hallucinosis is related with secondary language center which paly a important roll in cognition and imagination of music and also related with activation of temporal lobe and frontal lobe. METHODS: We report the case of musical hallucinosis with hearing impairment subsequent viral encephalitis. RESULTS: This case is activated both inferior temporal lobe and borderline of left temporal lobe and occipital lobe in the Single Photon Emission Computerized Tomography (SPECT). CONCLUSION: We predict that the result should be helpful to understand musical hallucinosis and auditory hallucination of schizophrenia.
Cognition ; Deafness* ; Encephalitis, Viral* ; Frontal Lobe ; Hallucinations ; Hearing Loss ; Humans ; Imagination ; Music* ; Neuropsychiatry ; Occipital Lobe ; Schizophrenia ; Temporal Lobe ; Tomography, Emission-Computed, Single-Photon

PURPOSE: To compare the intraocular pressure (IOP) measured by portable rebound tonometer and TonoPen applanation tonometer with pressure measured by Goldmann applanation tonometer (GAT) and analyze the factors affecting IOP disagreement between tonometers. METHODS: In a prospective study of 463 eyes, IOP was measured with Icare Pro(R) rebound tonometer, TonoPen AVIA(R) applanation tonometer, and GAT. Bland-Altman plot, intraclass correlation coefficient, Pearson's correlation analysis, and multiple regression analysis were performed to evaluate the agreement of IOP measured by each tonometer and the factors affecting the measurements. RESULTS: The IOP values measured by Icare Pro(R) and TonoPen AVIA(R) were consistently higher than those measured by GAT, but showed no significant differences with those measured by GAT (p = 0.307 and 0.114, respectively). In Bland-Altman plot, the IOP values measured by Icare Pro(R) and TonoPen AVIA(R) exhibited excellent agreement with those measured by GAT. Both Icare Pro(R)/GAT and TonoPen AVIA(R)/GAT differences increased with younger age (p = 0.041 and 0.049, respectively) and higher central corneal thickness (p = 0.019 and 0.035, respectively). CONCLUSIONS: IOPs measured by portable Icare Pro(R) rebound tonometer and TonoPen AVIA(R) applanation tonometer were significantly correlated with IOP measured by GAT. Therefore, such instruments can be useful when measuring IOP with GAT is difficult. However, central corneal thickness and age should be considered when measuring IOP with portable tonometers.
Intraocular Pressure* ; Iron-Dextran Complex ; Prospective Studies

PURPOSE: To report the first domestic case of choroidal neovascularization in a choroideremia patient treated with intravitreal bevacizumab injection. CASE SUMMARY: A 29-year-old male presented with a sudden decline in vision in the left eye. Fundus examination revealed areas of choriocapillaries and retinal pigment epithelium atrophy with macular hemorrhage. Fluorescein angiogram revealed vascular hyperfluorescence in the juxtafoveal area. Neurosensory detachment around the macula and increased central macular thickness was also observed using optical coherence tomography. Upon the diagnosis of choroideremia with choroidal neovascularization, the patient was treated with 1.25 mg intravitreal bevacizumab. Visual acuity improved after four injections of intravitreal Bevacizumab with improvement in both detachment and fluorescein leakage. CONCLUSIONS: In patients with choroideremia presenting sudden decline in vision, ophthalmologists should detect for possible choroidal neovascularization. The results from the present study show that judicious use of intravitreal Bevacizumab may be effective in such cases. Further studies with a large sample size and sufficiently long follow-up periods are required.
Adult ; Antibodies, Monoclonal, Humanized ; Atrophy ; Choroid ; Choroidal Neovascularization ; Choroideremia ; Eye ; Fluorescein ; Follow-Up Studies ; Hemorrhage ; Humans ; Male ; Retinal Pigment Epithelium ; Sample Size ; Tomography, Optical Coherence ; Vision, Ocular ; Visual Acuity ; Bevacizumab

Spontaneous intramural hematoma of the esophagus is a very rare disease. Varying degrees of submucosal rupture of the esophagus are caused by intramural hematoma of the esophagus. The causative factors include vomiting, an esophageal foreign body, endoscopic sclerotherapy for esophageal varices, equipment manipulation, drugs (e.g., warfarin and aspirin) and full-body disease (e.g., chronic renal failure, hemophilia and leukemia), and idiopathic causes have also been described. A 68-year-old male taking aspirin, clopidogrel and cilostazol was admitted to our hospital complaining of hematemesis. Spontaneous intramural hematoma of the esophagus was diagnosed by endoscopy. We report here on a case of spontaneous intramural hematoma of the esophagus that occurred after vomiting and the patient showed spontaneous improvement. We also review the relevant literature.
Aged ; Aspirin ; Endoscopy ; Esophageal and Gastric Varices ; Esophagus ; Foreign Bodies ; Hematemesis ; Hematoma ; Hemophilia A ; Humans ; Kidney Failure, Chronic ; Male ; Rare Diseases ; Rupture ; Sclerotherapy ; Tetrazoles ; Ticlopidine ; Vomiting ; Warfarin

It is known that in animals with increased intracranial pressure the cerebral perfusion is curtailed, but whether it is caused by deranged responsiveness of the cerebral vessel is not known. Thus, it was attempted in this study to find out the changes of cerebrovascular response to Kallikrein in the rabbits with increased ICP(20mmHg) under urethane-anesthesia. 1) intracarotid arterial kallikrein elicited increases in cerebral blood flow and decreases in blood pressure and arterial resistance. 2) Cerebral blood flow was significantly decreased in rabbits with increased ICP in comparison with the control rabbits. 3) Intraarterial kallikrein caused dose-depent increases of cerebral blood flow in both groups, but responses were significantly reduced in ICP-elevated group. 4) Kallikrein produced dose-dependent hypotensive effect in both groups with no significant difference between both groups. 5) Cerebrovascular resistance was greater in rabbits with elevated ICP(20 mmHg), but kallikrein induced decreases of cerebrovascular resistance in both groups to the same degree, 6) Above results suggested that increased ICP reduces the cerebral blood flow by increasing cerebrovascular resistance, but it does not modify the reponsiveness of cerebral vessel to kallikrein.
Animals ; Blood Pressure ; Intracranial Pressure ; Kallikreins* ; Perfusion ; Rabbits*

PURPOSE: To report a case of a macular hole resulting from accidental exposure to tattoo removal by the Q-Switched Nd:YAG laser, which was treated successfully by vitrectomy and silicone oil infusion. CASE SUMMARY: A 33-year-old man presented with decreased visual acuity after accidental exposure to a Q-Switched Nd:YAG laser. According to fundus examination, vitreous hemorrhage and macular edema were observed. After 21 days, a macular hole had developed which was treated by standard pars plana vitrectomy and gas tamponade. Unfortunately, closure was not obtained on the first attempt. Therefore, a second attempt using silicone oil infusion was performed. Four months after the initial visit, BCVA had increased to 20/50, and anatomical occlusion was achieved. CONCLUSIONS: The authors of the present study experienced an unusual case of macular hole developed from the Q-Switched Nd:YAG laser used to remove a tattoo. A satisfactory visual acuity was achieved after silicone oil infusion despite failure in the first surgery.
Adult ; Humans ; Macular Edema ; Retinal Perforations ; Silicone Oils ; Visual Acuity ; Vitrectomy ; Vitreous Hemorrhage

No abstract available.
Chorion* ; Chorionic Villi* ; Female ; Humans* ; Pregnancy ; Pregnancy, Ectopic* ; Telomerase*

Clonorchis sinensis infection is one of the most common parasitic infections that is widely distributed in Southern Korea as well as China, Japan, Taiwan, Hong kong, and Vietnam and countries in Eastern Asia. The disease is caused by the ingestion of infected raw or under- processed freshwater fish. The clinical manifestations depend on the number of flukes in a patient, the period of infestation, and the complications. We experienced a 10-year-old boy who had a history of ingestion of raw fresh-water Chinese mitten crab preserved in soy sauce and presented with chronic urticaria. The causal organism, Clonorchis sinensis, was found by the identification of parasite ova in stool. We report a rare case of chronic urticaria related to Clonorchis sinensis that was successfully treated with praziquantel and review the pertinent literature.
Asian Continental Ancestry Group ; Child ; China ; Clonorchis sinensis* ; Eating ; Far East ; Fresh Water ; Hong Kong ; Humans ; Japan ; Korea ; Male ; Ovum ; Parasites ; Praziquantel ; Soy Foods ; Taiwan ; Trematoda ; Urticaria* ; Vietnam