PURPOSE: The purpose of this study was to verify the effects of the integrated dementia managing programme for the elderly with mild dementia in which the physiological, cognitive, emotional, sociological and spiritual aspects have considered.METHODS: This study employed non-equivalent control group pre-post tests with the repeated measure design. The subjects of the study were 39 elderly with mild dementia (20 in the experimental group and 19 in the control group) who have admitted to two nursing homes in B city. The data were analyzed by repeated measures ANOVA.RESULTS: There were significant interactions between two groups and times in self-efficacy (p=.011), cognitive function (p < .001), depression (p=.005), spiritual well-being (p=.002), and quality of life (p=.037). The integrated dementia managing programme of this study showed significant positive effects on the quality of life for the elderly with mild dementia.CONCLUSION: On considering the current trends of aging and increasing number of the elderly with dementia, this integrated programme would be highly recommended to be used in nursing homes for the elderly with mild dementia, and contribute to improving their quality of life, and saving the social and medical expenses as well.

We developed a cardiac cell model to explain the phenomenon of mechano-electric feedback (MEF), based on the experimental data with rat atrial myocytes. It incorporated the activity of ion channels, pumps, exchangers, and changes of intracellular ion concentration. Changes in membrane excitability and Ca2+ transients could then be calculated. In the model, the major ion channels responsible for the stretch-induced changes in electrical activity were the stretch-activated channels (SACs). The relationship between the extent of stretch and activation of SACs was formulated based on the experimental findings. Then, the effects of mechanical stretch on the electrical activity were reproduced. The shape of the action potential (AP) was significantly changed by stretch in the model simulation. The duration was decreased at initial fast phase of repolarization (AP duration at 20% repolarization level from 3.7 to 2.5 ms) and increased at late slow phase of repolarization (AP duration at 90% repolarization level from 62 to 178 ms). The resting potential was depolarized from -75 to -61 mV. This mathematical model of SACs may quantitatively predict changes in cardiomyocytes by mechanical stretch.
Action Potentials ; Animals ; Ion Channels ; Membrane Potentials ; Membranes ; Models, Theoretical ; Muscle Cells* ; Myocytes, Cardiac ; Rats*

Primary malignant lymphomas of the lung are rare neoplasms representing 3.6% of all extranodal lymphomas and less than 1% of pulmonary malignancies, with its distinct clinicopathological features. A 60-year-old symptomatic man, who was a former non-smoker, had a cough and sputum. Chest roentgenogram and computed tomographic scan showed the presence of a posterior mass in the basal segment of the right lung. Transthoracic needle aspiration cytology was inadequate for the diagnosis of cancer. A subsequent right thoracotomy was carried out, which showed a primary pulmonary lymphoma of the bronchus-associated lymphoid tissue.
Cough ; Diagnosis ; Humans ; Lung ; Lung Neoplasms ; Lymphoid Tissue* ; Lymphoma* ; Middle Aged ; Needles ; Sputum ; Thoracotomy ; Thorax