1.A Case of Diseeminated Cryptococcosis.
Jong Cheol RYU ; Hyun Mo CHEONG ; Jun Taek PARK ; Jung Sik MIN ; Chang Hee CHOI
Journal of the Korean Pediatric Society 1986;29(9):86-92
No abstract available.
Cryptococcosis*
2.Metastic Renal Cell Carcinoma to the Prostate : a Case Report.
Jeong Hyun YOON ; Ki Hak SONG ; Hyun Cheol CHEONG ; Ji Sun SONG ; Mee Yon CHO ; Jae Mann SONG
Korean Journal of Urology 2000;41(1):187-189
No abstract available.
Carcinoma, Renal Cell*
;
Prostate*
3.Metastic Renal Cell Carcinoma to the Prostate : a Case Report.
Jeong Hyun YOON ; Ki Hak SONG ; Hyun Cheol CHEONG ; Ji Sun SONG ; Mee Yon CHO ; Jae Mann SONG
Korean Journal of Urology 2000;41(1):187-189
No abstract available.
Carcinoma, Renal Cell*
;
Prostate*
4.A case of endocervical stromal sarcoma.
Moon Hwan IM ; Young Cheol YU ; Young Ran HAN ; So Hyun PARK ; Cheong Rae ROH ; Soon Beom KANG
Korean Journal of Obstetrics and Gynecology 1991;34(3):444-449
No abstract available.
Sarcoma*
5.Primary Uterine Lymphoma: A Case Report.
In Joo CHEONG ; Se Hyun KIM ; Cheol Min PARK
Korean Journal of Radiology 2000;1(4):223-225
Primary lymphoma of the uterus is a rare disease, the reported characteristic MR imaging findings being homogeneous intermediate signal intensity of the indistinct mass on T1- and T2-weighted images, and the preservation of endome-trial lining and uterine architecture. We report a case of primary uterine lymphoma which showed tumoral necrosis, endometrial disruption and diffuse anterior vagi-nal wall involvement.
Case Report
;
Female
;
Human
;
Lymphoma, Lymphoblastic/*diagnosis
;
*Magnetic Resonance Imaging
;
Middle Age
;
Necrosis
;
Uterine Neoplasms/*diagnosis
;
Uterus/pathology
6.An Epidemiological Investigation of an Outbreak of Rubella Occurred in a Male High School in Kyongju.
Hae Kwan CHEONG ; Hyun Sul LIM ; Cheol JUNG ; Gyoung Yim HA
Korean Journal of Epidemiology 1998;20(2):202-211
This epidemiological study was carried out to investigate the sources of infection and modes of transmission of an outbreak of rubella that occurred among male high school students in Kyongju in march, 1996. 770 male students(286 third grade, 262 second grade, 222 first grade students) were selected as the study subjects. A questionnaire was completed by the subjects. The anti-Rubella antibodies IgM and IgG were examined and tested by ELISA on all sera from 770 students and the environmental status of class rooms, the dormitory conditions and study rooms were tested. The positive IgM result rate was 17.8% and when the IgM negative was combined with IgG positive the results was 74.9%. IgM IgG negative rates were 7.3%, however, out of a total 770 students. Amongst the older students, the IgM positive rate showed an increase(p<0.01). Out of 137 cases(with a cummulative incidence rate of 71.0%), there were 97 apparant cases(cummulative incidence rate 50.3%) and 40 inapparent cases(cummulative incidence rate 20.7%). Again, the cummulative incidence rate showed an increase in the older students(p<0.04). In the apparent cases, major symptoms included eruption(96.9%), fever(85.6%), lymphadenitis(82.5%), generalized aches and muscle tenderness(76.3%), and a sore throat(61.9%). These symptoms lasted anywhere from 2 degrees =/ 13 days, the average duration being 4 days in length. Initially, there were 9 people on third grade and suspected origin was from more than 2 external sources. It progressed from the upper grades down to the lower grades. In dormitory students, the cummulative incidence ratio was 1.70 and 1.78 amongst study room students.
Antibodies
;
Enzyme-Linked Immunosorbent Assay
;
Epidemiologic Studies
;
Gyeongsangbuk-do*
;
Humans
;
Immunoglobulin G
;
Immunoglobulin M
;
Incidence
;
Male*
;
Rubella*
;
Surveys and Questionnaires
7.Telomerase Activity in Musculoskeletal Tumors.
Soo Bong HAHN ; Kyo Ho SHIN ; Jin Woo LEE ; Kyu Hyun PARK ; Hyun Cheol CHEONG
Journal of Korean Orthopaedic Research Society 1998;1(1):40-47
Telomerase activity has been detected in many human immortal cell lines and tumor tissues. We studied telomerase activity in a series of human musculoskeletal tumors. Twenty-eleven tumors from 27 patients were studied using a sensitive PCR (polymerase chain reaction)-based technique, the TRAP(telomeric repeat amplication protocol) assay. Telomerase activity was present in seven tumors(25.9%). Telomerase activity was present in six of 18 malignant tumors(33.3%), while telomerase was active in one of 9 benign tumors(11.1%). Telomerase was active in 40% for osteosarcomas, 25% for soft tissue sarcomas, 16.7% for giant cell tumors of bone, and none for benign tumors. These results are a remarkablely low positive rate of telomerase activity in comparing with other types of carcinoma. In conclusion, it suggests that the musculoskeletal tumors, arisen from mesenchymal cells, follow different pathways of neoplastic progression or it is due to tile specific characteristics stick of sarcomas-abundant extracellular matrix and lack of tumor cells-differed tumor those of carcinomas.
Cell Line
;
Extracellular Matrix
;
Giant Cell Tumors
;
Humans
;
Osteosarcoma
;
Polymerase Chain Reaction
;
Sarcoma
;
Telomerase*
8.A Case of Clostridium Septicum Sepsis Associated with Malignancy.
Cheong Won PARK ; Joon Young SONG ; Cheol Hyun KIM ; Jang Wook SOHN ; Hee Jin CHEONG ; Woo Joo KIM ; Min Ja KIM ; Seung Chul PARK
Korean Journal of Infectious Diseases 2000;32(4):340-343
Clostridium septicum is a toxin producing anaerobic, motile, spore-forming, spindle shaped Gram positive rod that may cause devastating systemic illness in patients with neutropenia and underlying hematologic or gastrointestinal malignancy. Clostridium septicum sepsis usually have fulminating clinical courses, and unless the appropriate antibiotics are administered soon after admission, the outcome is fatal. We experienced a case of sepsis due to Clostridium septicum, in a 65-year-old woman with peripheral T-cell lymphoma and diabetes mellitus. She was admitted due to abdominal pain, fever, chilling, nausea, vomiting and watery diarrhea, followed by rapidly progressive course. This patient was not improved by intensive care and continuous antibiotic therapy, expired at the 4th hospital day. Clostridium septicum grew from premortem blood cultures.
Abdominal Pain
;
Aged
;
Anti-Bacterial Agents
;
Clostridium septicum*
;
Clostridium*
;
Diabetes Mellitus
;
Diarrhea
;
Female
;
Fever
;
Humans
;
Critical Care
;
Lymphoma, T-Cell, Peripheral
;
Nausea
;
Neutropenia
;
Sepsis*
;
Vomiting
9.A Case of Graves' Disease Following Subacute Thyroiditis.
Hyeong Cheol CHEONG ; Hye Jung NOH ; Byoung Hyun PARK ; Chung Gu CHO
Korean Journal of Medicine 2011;80(5):595-599
Subacute thyroiditis is a spontaneously resolving inflammatory disease of the thyroid gland, which is usually associated with a viral infection and genetic factors. In some cases of this disorder, thyroid autoantibodies can appear, probably due to the inflammatory release of thyroid antigens, althoughtheir pathophysiological role in the course of this disease is not yet fully understood. The occurrence of Graves' disease after subacute thyroiditis is extremely rare, and only a few cases have been reported. Here, we report a case of a middle-aged woman who developed Graves' disease after subacute thyroiditis.
Autoantibodies
;
Female
;
Graves Disease
;
Humans
;
Thyroid Gland
;
Thyroiditis
;
Thyroiditis, Subacute
10.A Prospective, Randomized, Comparative Clinical Investigation of the Effects of Sulodexide on Restenosis after Percutaneous Transluminal Coronary Balloon Angioplasty.
Jin Woo KIM ; Cheol Whan LEE ; Sang Sig CHEONG ; Duk Hyun KANG ; Myeong Ki HONG ; Jae Kwan SONG ; Jae Joong KIM ; Seong Wook PARK ; Seung Jung PARK
Korean Circulation Journal 1997;27(6):644-651
BACKGROUND: Restenosis remains as the major limitation of percutaneous translumainal coronary balloon angioplasty (PTCA). Although its mechanism remains incompletely understood, proliferative action of arterial smooth muscle cells has been found to play an important role on restenosis by neointimal formation after PTCA. Glycosaminoglycan-containing compounds, including Sulodexide (Vessel Due , ALFA, Wasserman, S.p.A, Italy), inhibit the proliferation and maigration of vascular smooth muscle cells in vitro. OBJECTIVES: This study was performed to assess the efficacy of Sulodexide, a glycosaminoglycan compound with antithrombotic and antiproliferative properties, in preventing restenosis after PTCA. METHOD: Two hundred eighty-four patients with ischemic heart disease were randomized to receive either the standard PTCA without Sulodexide in 144 patients (control group, M : F = 99 : 45, Age = 58 +9 or -9), 160 lesions or the standard PTCA with Sulodexide in 140 patients (treated group, M : F = 89 : 51, age = 58 +10 or -10), 158 lesions. Successful angioplasties were performed in 258 atheromatous coronary lesions in 224 patients for whom follow-up angiographic data were obtained 6 month later. Quantitative coronary angiographic analysis (QCA) was performed before , immediate after PTCA and 6-month later. Angiographic restenosis (>50% diameter stenosis at follow-up) was the primary end point : miniamal luminal diameter at follow-up angiogram was the secondary end point. RESULT: Successful PTCA was 97.6% and 97.5% in the standard PTCA with Sulodexide and the standard PTCA without Sulodexide, respectively. Although reference vessel size and minimal luminal diamater after PTCA were larger in the control group than in the Sulodexide group(2.94+0.11 or-0.11 vs 2.83+0.13 or -0.13 mm and 2.26+0.12 or -0.12 vs 2.18+0.08 or -0.08 mm, respectively, p=NS), there was a increased tendency of minimal lumen diameter at 6 months angiogram in the Sulidexide group than in the control group (1.12+0.50 or -0.50 vs 1.07 + 0.53 or -0.53 mm, respectively, p=NS). Angiographic restenosis occured in 42% of lesions in the Sulodexide group and 52% of the control group (p=NS). CONCLUSIONS: Sulodexide treatment had a tendency to reduce restenosis rate in 6 months after coronary angioplasty. However, further study is necessary to verify the antiproliferative effect of Sulodexide with much larger number of patients.
Angioplasty
;
Angioplasty, Balloon, Coronary*
;
Constriction, Pathologic
;
Follow-Up Studies
;
Humans
;
Muscle, Smooth, Vascular
;
Myocardial Ischemia
;
Myocytes, Smooth Muscle
;
Phenobarbital
;
Prospective Studies*