1.Dupuytren's Contracture: Report 3 cases
Chong Ho CHANG ; Bong Hyun KO ; Myung Sang MOON
The Journal of the Korean Orthopaedic Association 1972;7(1):141-145
Three cases of Dupuytrens contracture which developed in hands were reported along with review of literatures. Partial fasciectomy was done as the choice of treatment for them to improve impairment of function of the hands. No attributable causes for the developement of the disease were found.
Dupuytren Contracture
;
Hand
2.Frequency, Clinical Characteristics and Correlates of Premenstrual Syndrome in High School Students.
Hyung Joo CHANG ; Hyun Ghang JEONG ; Young Hoon KO ; Chang Su HAN ; Sook Haeng JOE
Korean Journal of Psychosomatic Medicine 2013;21(1):44-54
OBJECTIVES: To investigate the frequency and clinical characteristics of premenstrual syndrome(PMS)/premenstrual dysphoric disorder(PMDD) in high school students, and determine the correlates of PMS/PMDD in association with comorbid depression and anxiety. METHODS: A total of 1688 students were recruited from 5 high schools in Seoul, Korea. Subjects completed the questionnaire composed of scales to measure premenstrual symptoms, depression, and anxiety, as well as sociodemographic and reproductive variables. Subjects were categorized into 3 groups by using the Premenstrual Symptom Screening Tool(PSST) to determine the frequency and clinical characteristics of PMS/PMDD. Multivariate logistic regression was used to identify the correlates of PMS/PMDD. RESULTS: The frequency of moderate to severe PMS and PMDD was 20.1% and 6.4%, respectively. Irritability (78.8%), fatigue(76.4%), and emotional sensitivity(69.8%) were common premenstrual symptoms, and functional impairment in academic performance(67.1%) was dominant. Dysmenorrhea[odd ratio(OR)=3.68, 95% confidence interval(CI) 2.45-5.55], family history of PMS(OR=1.91, 95% CI 1.35-2.71), and use of oral contraceptive (OR=1.85, 95% CI 1.16-2.94) were associated with the increased risk of PMS/PMDD after adjustment for depression and anxiety. Negative attitude to menses(OR=15.60, 95% CI 3.61-67.42) was associated with the increased risk of PMS/PMDD, particularly in subjects without depression and anxiety. CONCLUSIONS: PMS was common, as the frequency of PMS more than moderate severity including PMDD exceeded 25%, and disrupted daily functioning in adolescents. PMS is associated with various sociodemographic and menstrual characteristics, and these associations are affected by comorbid depression and anxiety.
Adolescent
;
Anxiety
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Depression
;
Humans
;
Korea
;
Logistic Models
;
Mass Screening
;
Premenstrual Syndrome
;
Questionnaires
;
Weights and Measures
3.Urinary Tract Infection and Vesicoureteral Reflux in Children.
Hyun Suk LIM ; Chang Ro PARK ; Cheol Woo KO ; Ja Hoon KOO
Journal of the Korean Society of Pediatric Nephrology 1997;1(1):46-52
Fine needle aspiration biopsy cytology (FNA) for diagnosis of a variety of breast tum- ors has been proven to be a simple, safe, and cost saving diagnostic methodology with high accuracy. Cytologic specimens from 1,029 fine needle aspirations of the breast during last 3-year period were reviewed and subsequent biopsies from 107 breast lesions were reevaluated for cytohistological correlation. FNA had a sensitivity of 81.6% and a specificity of 98.3%. One out of 107 cases bio- psied revealed a false positive result (0.9%) and the case was due to misinterpretation of apocrine metaplastic cells in necrotic backgound as malignant cells. A false negative rate was 8.4% (9 of 107 cases biopsied). Six of 9 false negative cases were resulted from insufficient aspirates for diagnosis, and remaining three of 9 false negative cases revealed extensive necrosis with no or scanty viable cells on smears. The results indicate that for reducing false positive and false negative rates of FNA, an experienced cytopathologist and a proficient aspirator are of great importance.
Adenoma, Pleomorphic
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Aspirations (Psychology)
;
Biopsy
;
Biopsy, Fine-Needle
;
Breast
;
Carcinoma, Adenoid Cystic
;
Carcinoma, Mucoepidermoid
;
Child*
;
Cost Savings
;
Diagnosis
;
Humans
;
Necrosis
;
Needles
;
Sensitivity and Specificity
;
Urinary Tract Infections*
;
Urinary Tract*
;
Vesico-Ureteral Reflux*
4.Myeloid-Derived Suppressor Cells in Inflammatory Bowel Disease.
Yeon Jeong KIM ; Sun Young CHANG ; Hyun Jeong KO
Intestinal Research 2015;13(2):105-111
Immature myeloid cells, also known as myeloid-derived suppressor cells (MDSCs), include neutrophilic and monocytic myeloid cells, and are found in inflammatory loci and secondary lymphoid organs in mice with intestinal inflammation, inflammatory bowel disease (IBD) patients, and tumor tissues. However, the roles of MDSCs in IBD are not yet well understood, and there are controversies regarding their immunosuppressive functions in IBD. In addition, recent studies have suggested that endoplasmic reticulum (ER) stress in intestinal epithelial cells, especially in Paneth cells, is closely associated with the induction of IBD. However, the ER stress in MDSCs accumulated in the inflamed tissues of IBD patients is not yet fully understood. In the current review, we discuss the presence of accumulated MDSCs in the intestines of IBD patients, and further speculate on their physiological roles in the inflammatory condition with interleukin 17-producing cells, including Th17 cells. In particular, we will discuss the divergent functions of MDSCs in ER stressed intestinal environments, including their pro-inflammatory or immunosuppressive roles, based on the consideration of unfolded protein responses initiated in intestinal epithelial cells by ER stress.
Animals
;
Endoplasmic Reticulum
;
Endoplasmic Reticulum Stress
;
Epithelial Cells
;
Humans
;
Inflammation
;
Inflammatory Bowel Diseases*
;
Interleukin-17
;
Interleukins
;
Intestines
;
Mice
;
Myeloid Cells
;
Neutrophils
;
Paneth Cells
;
Th17 Cells
;
Unfolded Protein Response
5.Myeloid-Derived Suppressor Cells in Inflammatory Bowel Disease.
Yeon Jeong KIM ; Sun Young CHANG ; Hyun Jeong KO
Intestinal Research 2015;13(2):105-111
Immature myeloid cells, also known as myeloid-derived suppressor cells (MDSCs), include neutrophilic and monocytic myeloid cells, and are found in inflammatory loci and secondary lymphoid organs in mice with intestinal inflammation, inflammatory bowel disease (IBD) patients, and tumor tissues. However, the roles of MDSCs in IBD are not yet well understood, and there are controversies regarding their immunosuppressive functions in IBD. In addition, recent studies have suggested that endoplasmic reticulum (ER) stress in intestinal epithelial cells, especially in Paneth cells, is closely associated with the induction of IBD. However, the ER stress in MDSCs accumulated in the inflamed tissues of IBD patients is not yet fully understood. In the current review, we discuss the presence of accumulated MDSCs in the intestines of IBD patients, and further speculate on their physiological roles in the inflammatory condition with interleukin 17-producing cells, including Th17 cells. In particular, we will discuss the divergent functions of MDSCs in ER stressed intestinal environments, including their pro-inflammatory or immunosuppressive roles, based on the consideration of unfolded protein responses initiated in intestinal epithelial cells by ER stress.
Animals
;
Endoplasmic Reticulum
;
Endoplasmic Reticulum Stress
;
Epithelial Cells
;
Humans
;
Inflammation
;
Inflammatory Bowel Diseases*
;
Interleukin-17
;
Interleukins
;
Intestines
;
Mice
;
Myeloid Cells
;
Neutrophils
;
Paneth Cells
;
Th17 Cells
;
Unfolded Protein Response
6.A Case of Rett Syndrome Observed with Video-EEG Monitoring.
Hyun Mi KIM ; Young Ah LEE ; Tae Sung KO ; Hyung Nam MOON ; Chang Yee HONG
Journal of the Korean Pediatric Society 1994;37(5):718-725
Rett syndrome is progressive neurodegenerative disorder in female patients, characterized by autistic behavior, mental retardation, loss of purposeful hand skills, stereotypic hand movement, breathing dysfunction, severely impaired language, ataxia, and seizure. The diagnosis of Rett syndrome is based on its characteristic clinical manifestation and course. The electroencephalographic (EEG) findings of Rett syndrome are nonspecific, but a progressive deterioration in the EEG, characterized by a slowing of background activity and spike sharp wave discharges, may be observed. We experienced one case of Rett syndrome in a 5 year old girl having mental retardation, loss of purposeful hand skills, stereotypic hand movements (clapping, washing, hand-to-mouth), breathing dysfunction (hyperventilation/apnea). Her EEG findings on Video-EEG monitoring are excessive slowing waves during awake state and frequent spike discharges from left or centrotemporal area during sleeping. We report a case of Rett syndrome with brief review of related literatures.
Ataxia
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Child, Preschool
;
Diagnosis
;
Electroencephalography
;
Female
;
Hand
;
Humans
;
Intellectual Disability
;
Neurodegenerative Diseases
;
Respiration
;
Rett Syndrome*
;
Seizures
7.Mosaic-trisomy 22 with Inv(22)(p12-q13)..
In Jang CHOI ; Ihn Hwan LEE ; Bok Hyun KO ; Sung Ik CHANG
Korean Journal of Physical Anthropology 1991;4(2):145-149
No abstract available.
8.Low Grade Malignant Peripheral Nerve Sheath Tumor Arising from Solitary Neurofibroma.
Hyun Joo LEE ; Wonjeong KIM ; Hoon Soo KIM ; Hyun Chang KO ; Byung Soo KIM ; Moon Bum KIM ; Margaret SONG
Korean Journal of Dermatology 2016;54(2):158-160
No abstract available.
Neurofibroma*
;
Peripheral Nerves*
9.Morphological Characteristics of the Atrium as an Endocrine Organ: I. Luminal Structure of Atria in Various Animals Using Corrosion Casting Method.
Moo Sam LEE ; Hong KIM ; Byoung Moon KO ; Woo Song JEONG ; Byung Keon PARK ; Chang Hyun LEE
Korean Journal of Physical Anthropology 1994;7(1):33-46
The internal morphology of the right and left atria of rabbit, cat, pig, and human, particularly on the luminal structures of the auricle, were observed by stereomicroscope improving corrosion casting method using latex. Structures of the right auricular casts markedly differ from those of the left side, consisting of defined surface sturctures with distinct folds and branching patterns. The main atrial region consists of smooth surfaced single mass of the latex, and the auricular region is characterized by well developed branching patte and delicate small folds. The results of this study indicate that auricula have well organized duct-like luminal structures and many small pouches (out-pocketings) expanding the internal wall of the duct-like structures and small pouches. The endocardial nuclear imprints on the surface of the folds in the auricular region appeared larger and deeper than those on the atrium proper region of the atrial cast. These morphological observation will be aid in understanding structures of auricular lumen, regional differences of the endocardium and their function to the secretory process of atrial natriuretic peptide (ANP) release.
Animals*
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Cats
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Corrosion Casting*
;
Corrosion*
;
Endocardium
;
Humans
;
Latex
;
Methods*
;
Phenobarbital*
;
Secretory Pathway
10.A Case of High-flow Priapism Treated by Superselective Embolizations of Bilateral Cavernosal Arteries.
Woo Jin KO ; Chang Hee HONG ; Hyun Jick CHUNG ; Moo Sang LEE
Korean Journal of Urology 1999;40(11):1573-1576
We report a case of priapism secondary to bilateral rupture of the cavernosal arteries following perineal blunt trauma in a 34 year old man. He complained of painless but persistent erection for the period of 1 week. We confirmed non-ischemic high-flow priapism by arterial blood gas analysis, Doppler ultrasonography and arteriography. Arteriography showed a leakage on both sides of the end of the cavernosal arteries and the leakage was blocked by superselective cavernosal artery embolization. After the embolization, tumescence began to disappear and the detumescence process was completed on the third day. The examination of the patient after 4 months following embolization revealed that the patient was fully free of priapism and returned to the normal erectile status like before his priapism. During 2 years of follow up, the patient had no complications such as priapism or impotence.
Adult
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Angiography
;
Arteries*
;
Blood Gas Analysis
;
Erectile Dysfunction
;
Follow-Up Studies
;
Humans
;
Male
;
Priapism*
;
Rupture
;
Ultrasonography, Doppler