1.CD8+ Lymphomatoid Papulosis.
Annals of Dermatology 2011;23(1):104-107
Lymphomatoid papulosis (LyP) is defined as a histologically malignant, but clinically benign condition. It can appear as erythematous pink to purple papules or nodules. Immunophenotyping studies of the lymphomatoid papulosis lesions have shown a predominance of a CD4 expression and negativity for CD8. However, a positive CD8 expression has rarely been reported for LyP. Herein we report on a case of CD8 positive lymphomatoid papulosis in a 43-year-old man. The patient presented with erythematous, asymptomatic papules on the left axilla and thigh. Histopathologically, there was a wedge-shaped infiltrate composed of a mixture of various cell types, including lymphocytes, histiocytes, neutrophils and large atypical lymphoid cells. Immunophenotyping revealed the neoplastic cells were positive for CD3, CD8 and CD30 and they were negative for CD4, CD20 and CD56.
Adult
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Axilla
;
Histiocytes
;
Humans
;
Immunophenotyping
;
Lymphocytes
;
Lymphomatoid Papulosis
;
Neutrophils
;
Thigh
2.Tetralogy of Fallot associated with a Cardiac Rhabdomyoma in a Infant.
Chan Uhng JOO ; Hyun Seup SIM ; Eun Kyung CHOI ; Min Ho KIM
Korean Circulation Journal 2001;31(6):588-591
No abstract available.
Humans
;
Infant*
;
Rhabdomyoma*
;
Tetralogy of Fallot*
3.Efficacy of the Sutureless Amniotic Membrane Patch for the Treatment of Ocular Surface Disorders.
Jenny YANG ; Hyun Chan SIM ; Dae Jin PARK
Journal of the Korean Ophthalmological Society 2012;53(1):27-36
PURPOSE: To evaluate the efficacy of the sutureless amniotic membrane (AM) patch for the treatment of ocular surface disorders. METHODS: A sutureless AM patch using a silicone ring was utilized to treat neurotrophic ulcer, persistent epithelial defect (PED), Shield ulcer, chemical injury and Stevens-Johnson syndrome. Primary outcome was the time to complete corneal and conjunctival epithelialization. Secondary outcome was the number of repeated insertions and complications of the inserted ring. RESULTS: Neurotrophic ulcer was observed in 4 eyes, PED in 2 eyes, Shield ulcer in 1 eye, chemical injury in 4 eyes and Stevens-Johnson syndrome in 4 eyes. The mean (SD) time to complete epithelialization was 13 (7.2) days (6-20 days) in neurotrophic ulcer, 17.5 (7.7) days (12-23) in PED, 5 days in Shield ulcer, 10.6 (6.6) days (3-15) in chemical injury and 13.5 (0.7) days (13-14) in Stevens-Johnson syndrome. There were no protrusion or mechanical trauma of the inserted ring. In 1 case of neurotrophic ulcer and 1 refractory case of chemical injury, repeated insertion was performed due to incomplete healing after dissolution of the AM. In 2 eyes with Stevens-Johnson syndrome, repeated insertion was necessary with heavy accumulation of inflammatory debris on the AM. No symblepharon or fornix contracture was found in chemical injury or Stevens-Johnson syndrome patients. CONCLUSIONS: The sutureless AM patch using a silicone ring was shown to be effective and safe for the treatment of ocular surface disorders. The patch can help surgeons avoid suture-related trauma to the ocular surface during the acute inflammatory period.
Amnion
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Contracture
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Eye
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Silicones
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Stevens-Johnson Syndrome
;
Ulcer
4.A clinical study of 218 cases of Tsutsugamushi disease.
Chang Hyun PARK ; Chan Woong PARK ; Seung Sig SIM ; Mann JUNG ; Young Mi LEE ; Hyung Sun RYEU ; Ji Woon KIM
Korean Journal of Medicine 1993;45(4):497-506
No abstract available.
Scrub Typhus*
5.Factors Associated with Post Stroke Shoulder Subluxation.
Jae Hyun LEE ; Woo Hyun JEON ; Ho Joong JEONG ; Ghi Chan KIM ; Young Joo SIM
Kosin Medical Journal 2015;30(1):59-67
OBJECTIVES: Shoulder subluxation is common complication after stroke. And it can result in delayed neurological recovery in hemiplegic stroke patients. The aim of this study is identifying the incidence and associating factors of shoulder subluxation in stroke patients. METHODS: Stroke patients from 1 rehabilitation center from January 2008 to January 2012 were enrolled in the present study. The basic demographic data were registered at the time of admission or transfer to rehabilitation center. To assess the shoulder subluxation, we have used fingers' breadth method and plain radiography. We diagnosed shoulder subluxation with vertical distance (VD) were more than 12.4cm on plain anteroposteior view. And then shoulder subluxation was analyzed with associated factors. RESULTS: Of 154 stroke patients, this retrospective study included 109 patients who met the inclusion criteria, 28 patients had shoulder subluxation. After univariated analysis, shoulder subluxation was significantly associated with motor power of shoulder and elbow, loss of proprioception, stroke duration and functional ability. Especially elbow extensor less than poor grade is mostly related to shoulder subluxation among the motor powers. Then multivariated analysis was carried out including all significant subjects, elbow extensor less than poor grade, loss of proprioception and stroke duration more than 6 months were related to shoulder subluxation. CONCLUSIONS: Post stroke shoulder subluxation was commonly observed, and the incidence was 25.6% in this study. Shoulder subluxation was correlated with muscle power of elbow(less than F grade), loss of proprioception and stroke duration more than 6 months.
Elbow
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Humans
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Incidence
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Proprioception
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Radiography
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Rehabilitation
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Rehabilitation Centers
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Retrospective Studies
;
Shoulder*
;
Stroke*
6.Electrocardiographic and Echocardiographic Characterisitics of Wolff-Parkinson-White Syndrome in Preschool Children.
Jeoung Min CHU ; Hyun Sup SIM ; Soo Chul CHO ; Chan Uhng JOO
Journal of the Korean Pediatric Society 2002;45(9):1097-1105
PURPOSE: This study was conducted to estabilish the prevalence, clinical features and relationship between ECG findings and echocardiographic findings of Wolff-Parkinsion-White(WPW) syndrome in asymptomatic preschool children. METHODS: An electrocardiographic screening study was performed on 77,824 preschool children in Jeonbuk province from April, 1999 to August, 2001. Patients with WPW syndrome underwent echocardiographic study. RESULTS: Twenty three patients with WPW syndrome were discovered by electrocardiographic screening of preschool children. The prevalence rate was 2.9 per 10,000 preschool children and there was no significant sexual difference. Two patients had a history of symptoms related to tachyarrythmia. According to the ECG classification of Rosenbaum et al., five patients were type A and 18 were type B. Utilizing the criteria of Gallagher et al, right anterior, 12 patients; right anteiror paraseptal, four patients; left anteiror, three patients. Nineteen of 23 patients underwent echocardiographic study. Four of five patients with type A WPW syndrome had abnormal early systolic anterior motion of left ventricular posterior wall. Twelve of 14 patients with type B had abnormal interventricular septal motion characterized by early sytolic posterior motion immediately after inscription of the delta wave. CONCLUSION: The prevalence rate of preschool children in Jeonbuk province was 2.9/10,000. By the classification according to the electrocardiographic findings, the accessory pathway location was dominant right side than left side. In the echocardiographic study, type A WPW syndrome showed abnormal left ventricular posterior wall motion and type B WPW showed abnormal interventricular septal motion.
Child, Preschool*
;
Classification
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Echocardiography*
;
Electrocardiography*
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Humans
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Jeollabuk-do
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Mass Screening
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Prevalence
;
Wolff-Parkinson-White Syndrome*
7.A case of combined adrenocorticotropic hormone(ACTH) and growth hormone(GH) deficiency.
Hyung Seon RYEU ; Seung Sig SIM ; Mann JUNG ; Chang Hyun PARK ; Chan Woong PARK ; Young Mi LEE ; Seok Bae CHEON ; Sang Ku KANG ; Yong MOON ; Ji Woon KIM
Korean Journal of Medicine 1993;45(4):522-526
No abstract available.
8.Changes of the Clinicopathological Characteristics and Survival Rates of Gastric Cancer with Gastrectomy: 1990s vs early 2000s.
Young Kwan SIM ; Chan Young KIM ; Yeon Jun JEONG ; Jong Hun KIM ; Yong HWANG ; Doo Hyun YANG
Journal of the Korean Gastric Cancer Association 2009;9(4):200-206
PURPOSE: The incidence of upper gastric cancer and especially the diffuse type have increased in western countries. The aim this study was to investigate the chronologic changes of the clinicopathological features and survival rates of Korean upper gastric cancer patients. MATERIALS AND METHODS: 1,638 gastric cancer patients who underwent gastrectomy were included in this study and they were divided into two groups; the 1990's (1991~1999, n=987) and the early 2000's (2000~2003, n=651). We evaluated the differences of the clinicopathologic features and the factors that affected the survival rates by univariative and multivariative analysis. RESULTS: The older age (>60) patients increased from 42.7% to 50.7% respectively. Being overweight (body mass index> or =23) also increased from 31.5% to 43.2%. For the pathology, the incidence of stage Ia gastric cancer increased (29.8% to 44.5%) and the incidence of stage IV gastric cancer decreased (23.5% to 11.8%). Yet there was no difference according to the WHO classification, Lauren's classification and the location of tumor between the groups. The 5 year survival rates increased 67.7% to 83.7%, according to the group. Multivariative analysis showed that the odd ratios of the early 2000s was 0.715 (95% CI; 0.555~0.921) as compared to that of the 1990s. CONCLUSION: There were no changes of the clinicopathologic features, like the pattern in western countries, although the incidence early gastric cancer, old age patients and overweight patients increased. The survival rate of early 2000s was better that that of the 1990s.
Gastrectomy
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Humans
;
Incidence
;
Overweight
;
Stomach Neoplasms
;
Survival Rate
9.Development of Dermatomyofibroma in a Male Infant.
Ji Hyun SIM ; Jaeyoung SHIN ; Daniel P VANDERSTEEN ; You Chan KIM
Annals of Dermatology 2011;23(Suppl 1):S72-S74
Dermatomyofibroma is a rare benign cutaneous mesenchymal neoplasm of the fibroblasts and myofibroblasts. The majority of dermatomyofibromas present as red-brown discolored plaques or nodules, commonly located on the shoulder, upper arm, axilla, neck, and/or upper trunk. These lesions develop most frequently in young female patients at a mean of 28-years-of-age. Herein, a case of dermatomyofibroma is reported that developed in an infant. A 4-month-old boy presented with an ill-defined bluish firm plaque on the trunk that developed 1 month after birth. Histopathologically, there was proliferation of bland-looking spindle cells with fascicular arrangement in the dermis and subcutaneous tissue. Immunohistochemistry showed that most of the tumor cells expressed diffuse positivity for vimentin and smooth muscle actin, but were negative for S-100 protein, desmin, and CD34.
Actins
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Arm
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Axilla
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Dermis
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Desmin
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Female
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Fibroblasts
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Humans
;
Immunohistochemistry
;
Infant
;
Male
;
Muscle, Smooth
;
Myofibroblasts
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Neck
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Parturition
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S100 Proteins
;
Shoulder
;
Subcutaneous Tissue
;
Vimentin
10.A case of endometrial osseous metaplasia of a referred endometria l cancer patient.
Jeong Hwan KIM ; Chung Yeon SIM ; Hyun Chul KIM ; Myung Chul SHIN ; Tae Won SUNWOO ; Chan LEE
Korean Journal of Gynecologic Oncology and Colposcopy 1998;9(4):501-503
Endometrial osseous metaplasia is a rare condition. The etiology and pathogenesis remain controversial. In most cases, the development of this condition is observed to be related to the history of abortion, either spontaneous or therapeutic and also, frequently associated with menstrual irregularity and endometritis. Patients usually present with secondary amenorrhea, irregular menstruation, pain, and dysmenorrhea. The authors recently experienced a case of endometrial osseous metaplasia of a referred endometrial cancer patient who had no history of abortion at all. We report this case with a brief review of the literature.
Amenorrhea
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Dysmenorrhea
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Endometrial Neoplasms
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Endometritis
;
Endometrium*
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Female
;
Humans
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Menstruation
;
Metaplasia*