2.A Study on the State of Recognition and Experience of Love; Sex Knowledge; and Self-esteem of Youths.
Shin Ae PARK ; Myung Ja WANG ; Nam Hyun CHA
Journal of Korean Academy of Community Health Nursing 2006;17(2):242-252
No abstract available.
Adolescent*
;
Humans
;
Love*
3.Carcinoma in situ of the urinary bladder in bladder washing cytology.
Doo Hyun CHUNG ; In Ae PARK ; Eui Keun HAM
Korean Journal of Cytopathology 1991;2(1):51-55
The diagnosis of carcinoma in situ of urinary bladder is difficult in that the symptoms and cystoscopic findings are nonspecific. The cytology of urine could be helpful for diagnosis of carcinoma in situ of urinary bladder. We present a case of bladder washing cytology of carcinoma in situ. A 54 year old man presented with dysuria for 1 year. Cystoscopic findings revealed multifocal reddish trabeculated lesions. The bladder washing cytology revealed rather uniform tumor cells which were singly scattered or forming syncytium in the clean background. The nuclei were round to oval with inconspicious nucleoli. The cystoscopic biopsy revealed typical histologic features of carcinoma in situ of urinary bladder.
Biopsy
;
Carcinoma in Situ*
;
Diagnosis
;
Dysuria
;
Giant Cells
;
Humans
;
Middle Aged
;
Urinary Bladder*
4.The effect of both oophorectomy on serotonin level in cerebral cortex and hippocampus of the female Sprague-Dawley rat.
Eun Mi KO ; Hyun Ae JEON ; Man Chul PARK
Korean Journal of Obstetrics and Gynecology 2000;43(11):1926-1931
OBJECTIVE: The purpose of this study is to investigate the effect of chronic deprivation of estradiol on the serotonin level in Sprague-Dawley rat's cerebral cortex and hippocampus. METHODS: One hundred of female Sprague-Dawley rats were taken care for seven to eight weeks, then they were randomly assigned into two group; fifty rats underwent bilateral oophorectomy & the remaining rats were the control group. Six months after oophorectomy, brain tissue was extracted from cerebral cortex and hippocampus and then homogenated: this was done in the both groups. The upper layer of the homogenated substance was taken and frozen and finally dried up. The next process was marking with PITC, quantification through HPLC and comparing with authentic serotonin. Protein quantity was measured by using Bradford method. RESULTS: Comparison between the bilateral oophorectomy group and the control group for serotonin content in the cerebral cortex was 134.2+/-14.3 nmol/mg protein(mean+/-SEM) and 122.5+/-11.6 nmol/mg protein in each group. As for the serotonin content in the hippocampus was 148.8+/-13.9 nmol/mg protein and 132.9+/-13.7 nmol/mg protein in each group. It shows that, there was no significant difference in the serotonin level, in the two areas mentioned above. CONCLUSION: The effect of estradiol on the serotonin level may be dependent on the hormonal change duration. Chronic effect of hypoestrogenism might have no effect on tryptophan hydroxylase and monoamine oxidase, thus not changin the serotonin level. These data supported the previous findings that chronic hypoestrogenism had no effect on serotonin level.
Animals
;
Brain
;
Cerebral Cortex*
;
Chromatography, High Pressure Liquid
;
Estradiol
;
Female
;
Female*
;
Hippocampus*
;
Humans
;
Monoamine Oxidase
;
Ovariectomy*
;
Rats*
;
Rats, Sprague-Dawley*
;
Serotonin*
;
Tryptophan Hydroxylase
5.The Correlation of Neoadjuvant Chemotherapy Responsiveness with The Expression of BCL-2, Bax, VEGF, PCNA and The Pattern of Apoptosis in Cervical Cancer.
Yong Beom KIM ; Noh Hyun PARK ; In Ae PARK ; Hyo Pyo LEE
Korean Journal of Gynecologic Oncology and Colposcopy 2000;11(1):24-37
The purpose of this study was to identify the relationship between the clinical response to neoadjuvant chemotherapy and PCNA and VEGF protein expression, apoptosis and its related gene expression such as Bcl-2 and Bax in cervical cancer. We retrospectively reviewed 30 patients with locally advanced or bulky cervical cancer treated with three courses of neoadjuvant chemotherapy followed by radical hysterectomy or radiation therapy at Seoul National University Hospital from June 1995 to June 1998. The specimen were obtained before chemotherapy by colposcopy directed biopsy. The protein expressions of Bcl-2, Bax, VEGF and PCNA were examined by immunohisto- chemical staining and the apoptosis was examined by TUNEL staining. These results were compared with chemotherapeutical response which was evaluated by colposcopy or CT/MRI. There were 2 CR(complete response), 19 PR(partial response) and 9 NC(no change) and there was no progressive disease. There was no significant difference between responder and nonresponder according to the age, tumor size and FIGO stage. The 3 year survival rates of responder and nonresponder were 90.0% and 66.7% respectively and there was significant difference between two groups(p=0,015). The expression of Bcl-2 and Bax was positive in 23.3%(7/30) and 46.7%(14/30). The expression of VEGF was positive in 83.3%(25/30). PCNA PI(positive index), defined as PCNA positive cells in percentage was more than 25.0% in 20 cases. Apoptotic index, defined as the number of the cells undergoing apoptosis per 1,000 tumor cells, ranged from 3 to 53(mean 22.3). Although there was no significant relationship between the clinical response to neoadjuvant chemotherapy and the expre- ssion of Bcl-2, Bax, VEGF and PCNA PI, apoptotic index was significantly higher in responder than nonresponder when the cutoff value of positive was defined as apoptotic index more than 5(p=0.032). In conclusion, the evaluation of the pattern of apoptosis before neoadjuvant chemothera- py is potentially useful for the prediction ofz tumor response to neoadjuvant chemotherapy for cervical cancer.
Apoptosis*
;
Biopsy
;
Colposcopy
;
Drug Therapy*
;
Gene Expression
;
Humans
;
Hysterectomy
;
In Situ Nick-End Labeling
;
Proliferating Cell Nuclear Antigen*
;
Retrospective Studies
;
Seoul
;
Survival Rate
;
Uterine Cervical Neoplasms*
;
Vascular Endothelial Growth Factor A*
6.Development of a Nursing Care Decision Support SystemforHealth Problems of The Elementary and Secondary School Students.
Journal of Korean Society of Medical Informatics 2009;15(1):71-81
OBJECTIVE: The aim of this study was to develop a decision support system that helps school nurses manage health problems they encounter while caring for the elementary and secondary school students, and evaluate usability of it. METHODS: Knowledge was aquired by literatures review and interviews with senior school nurses and was validated by another group of school nurses. The Omaha System was used as a standardized nursing terminology to describe nursing diagnoses and interventions. The system was developed under the Windows environment. C++ was used as a program language and MS Structured Query Language as a database. To investigate usability of the system, 30 school nurses in elementary and secondary schools were recruited and asked to apply it to nursing problems they encountered in actual students care setting. RESULTS: The decision support system with seven major signs and symptoms was developed. It automatically makes a nursing diagnosis based on the input data, and also provides nursing interventions with evidence. It was proven that the system was very useful for school nurses to manage students` health problems. CONCLUSION: The system will contribute to development of expert knowledge concerning student's health problems and improve the quality of school nursing and professionalism.
Expert Systems
;
Humans
;
Nursing
;
Nursing Care*
;
Nursing Diagnosis
;
Nursing Process
;
School Nursing
7.Survey Study of Current Status of and Need for Mental Health Education Enhancing Protective Factors in the Elementary Schools.
Journal of Korean Academy of Community Health Nursing 2016;27(1):9-20
PURPOSE: The purpose of this study was to survey the current status of mental health education and need for mental health education enhancing protective factors in the elementary schools. METHODS: We surveyed 10 school health teachers and 328 fifth- and sixth-grade students using 19- and 20-item questionnaires, respectively. RESULTS: All of the teachers and 65.2% of the students replied that they were either teaching or being taught mental health in school. Topics covered suicide, depression, school violence, and Internet addiction. All of the teachers and 84.1% of the students expressed the need for mental health education enhancing protective factors in school. Both groups replied that two sessions are enough. The teachers preferred role play and discussion as teaching methods, and audiovisual materials and computer as instructional media. The students preferred lecture and role play as teaching methods, and audiovisual materials and smartphone as instructional media. Both groups ranked self-esteem, parent-child relationship, peer relationship, and emotional regulation as the most important topics to be covered in the education. CONCLUSION: There is a high demand for mental health education enhancing protective factors. Therefore, it is recommended to develop educational programs enhancing protective factors by enabling formal and informal learning using smartphone.
Depression
;
Education*
;
Health Education
;
Humans
;
Internet
;
Learning
;
Mental Health*
;
Needs Assessment
;
Parent-Child Relations
;
School Health Services
;
School Nursing
;
Suicide
;
Teaching
;
Violence
;
Smartphone
8.Designing a semantic network for Unified Nursing Language System.
Sookyung HYUN ; Hyeoun Ae PARK
Journal of Korean Society of Medical Informatics 2000;6(3):39-50
Nursing language plays an important role in describing and defining nursing phenomena and nursing actions. There are numerous vocabularies describing nursing diagnoses, interventions, and outcomes in nursing domain. However, lack of a standardized, unified nursing language is considered as a problem for further development of the discipline of nursing. With this background this study was conducted to construct a semantic network based on cross mapping of existing nursing terminologies. specifically NANDA taxonomy I, Omaha system, HHCC. and NIC. which arc recognized as standard terminology by the American Nurses Association. The nursing semantic network was proposed with the cross mapping results based on the UMLS semantic network.
American Nurses' Association
;
Classification
;
Nursing Diagnosis
;
Nursing*
;
Semantics*
;
Unified Medical Language System
;
Vocabulary
9.Study on diagnostic efficiency of several parameters in DIC.
Hyun Young CHI ; Hyoun Tae KIM ; Young Joo CHA ; Ae Ja PARK
Korean Journal of Clinical Pathology 1991;11(2):387-395
No abstract available.
Dacarbazine*
10.Drug Abuse Status and Its Determinants of Male High School Students in Taegu.
Jung Rak NAM ; Sin KAM ; Jae Yong PARK ; Chang Hyun HAN ; Young Ae HA
Korean Journal of Preventive Medicine 1996;29(3):451-470
To identify the drug abuse status and its determinant factors in high school boys in Taegu, the study was performed from April to May, 1995. Study population were selected by cluster sampling method and total 5,665 students replied to the self-administered questionnaire survey(2,207 in academic high school, 3,458 in business high school). The major findings were as follows; The proportion of drinking, smoking experience was 55.0%, 45.8%, respectively, and the proportion of current drinker, current smoker was 27.2%, 27.5%. The drinking, smoking experience rate of second grade students was higher than first grade and it was higher in business high school boys. The proportion of a stimulant, a hallucinogen, hemp leaf cigarets experience was 3.2%, 1.6%, 0.1%, respectively. Drug abuse had significant association with home environment(lower economic status, frequent move, death of father or mother, apart from family), parents environment(parents' indifference, parents' drinking and smoking, etc.), school life(lower school grades, intimate friend's drug abuse, etc.), generous attitude to drug abuse, higher level of stress. Students who replied that the law prohibited immature person(students) from drinking and smoking showed lower drug abuse rate. In multiple logistic regression analysis, second grade students, business high school students, parents' indifference, lower school grades, intimate friend's drug abuse, no recognition of the fact that the law prohibits high school students from drinking and smoking, generous attitude to drug abuse, higher level of stress were significantly related with alcohol abuse and smoking. Other drugs abuse were related with above factors. On consideration of above findings, to prevent students from drug abuse, we have to try together in house, school, and society.
Alcoholism
;
Cannabis
;
Commerce
;
Daegu*
;
Drinking
;
Fathers
;
Humans
;
Jurisprudence
;
Logistic Models
;
Male*
;
Mothers
;
Parents
;
Surveys and Questionnaires
;
Smoke
;
Smoking
;
Substance-Related Disorders*