1.A Case of Coronary Stenting in the Management of Myocardial Ischemia Caused by Myocardial Bridging.
Seung Hyuk CHOI ; Sang Jun SHIM ; Ki Hyun BYUN ; Donghoon CHOI ; Won Heum SHIM
Korean Circulation Journal 2001;31(9):940-944
Myocardial bridging is defined as a condition where a segment of a major epicardial coronary artery running intramurally through the myocardium. Although this abnormality is usually regarded as an incidental finding at angiography, it has been associated with myocardial ischemia, infarction, and sudden death. Standard treatment involves beta-adrenergic receptor blockers, surgery with dissection of the overlying muscle fibers, or coronary artery bypass grafting. A few cases of the intracoronary stent implantation have been reported as an alternative treatment in individual patients with myocardial bridging. We report a case of intracoronary stenting in a severe systolic narrowing at the middle segment of the left anterior descending artery in a patient complaining of recurrent chest pain despite medical treatment.
Angiography
;
Arteries
;
Chest Pain
;
Coronary Artery Bypass
;
Coronary Vessels
;
Death, Sudden
;
Humans
;
Incidental Findings
;
Infarction
;
Myocardial Bridging*
;
Myocardial Ischemia*
;
Myocardium
;
Running
;
Stents*
2.The role of cyclooxygenase metabolities in the pathogeneticmechanism of endotoxin-induced acute lung injury in domestic pigs.
Chul Gyu YOO ; Ki Ho JEONG ; Hyung Seok CHOI ; Hyuk Pyo LEE ; Young Whan KIM ; Sung Koo HAN ; Young Soo SHIM ; Keun Youl KIM ; Yong Chol HAN
Tuberculosis and Respiratory Diseases 1992;39(1):42-54
No abstract available.
Acute Lung Injury*
;
Prostaglandin-Endoperoxide Synthases*
;
Sus scrofa*
3.The role of reactive oxygen free radical in the pathogenetic mechan- ism of endotoxin-induced acute lung injury in domestic pigs.
Young Whan KIM ; Chul Gyu YOO ; Ki Ho JEONG ; Hyung Seok CHOI ; Hyuk Pyo LEE ; Sung Koo HAN ; Young Soo SHIM ; Jeun Youl KIM ; Yong Chol HAN
Tuberculosis and Respiratory Diseases 1991;38(4):357-371
No abstract available.
Acute Lung Injury*
;
Oxygen*
;
Sus scrofa*
4.Pituicytoma with Significant Tumor Vascularity Mimicking Pituitary Macroadenoma.
Hyuk Ki SHIM ; Seung Heon CHA ; Won Ho CHO ; Sung Hye PARK
Brain Tumor Research and Treatment 2017;5(2):110-115
A 19-year-old man presented with bitemporal hemianopsia and was found to have a large sellar and suprasellar tumor, resembling a pituitary macroadenoma. Emergency transsphenoidal approach was attempted because of rapid visual deterioration with headache. However, the approach was complicated and stopped by uncontrolled hemorrhage from the tumor. After conventional cerebral angiography and recognition of an unusual pathology, transcranial approach was achieved to prevent permanent visual loss. The final pathological diagnosis was pituicytoma with epithelioid features. Pituicytoma is a rare low-grade tumor (WHO Grade I) of pituicytes involving the sellar and suprasellar region, and originating from special glial cells of the neurohypophysis. Because of the high vascularity, the firm consistency, and invasion to surrounding neurovascular structures, a pituicytoma should be included in the differential diagnosis of a mass in the sellar and suprasellar area if the tumor shows high enhancement with vascular components. We report a case of rare pituicytoma mimicking a pituitary macroadenoma with massive hemorrhage to disturb surgery.
Cerebral Angiography
;
Diagnosis
;
Diagnosis, Differential
;
Emergencies
;
Headache
;
Hemianopsia
;
Hemorrhage
;
Humans
;
Neuroglia
;
Pathology
;
Pituitary Gland, Posterior
;
Young Adult
5.Safety and Cost-Effectiveness of Bridge Therapies for Invasive Dental Procedures in Patients with Mechanical Heart Valves.
Ki Bum WON ; Seung Hyun LEE ; Hyuk Jae CHANG ; Chi Young SHIM ; Gue Ru HONG ; Jong Won HA ; Namsik CHUNG
Yonsei Medical Journal 2014;55(4):937-943
PURPOSE: Bridge anticoagulation therapy is mostly utilized in patients with mechanical heart valves (MHV) receiving warfarin therapy during invasive dental procedures because of the risk of excessive bleeding related to highly vascular supporting dental structures. Bridge therapy using low molecular weight heparin may be an attractive option for invasive dental procedures; however, its safety and cost-effectiveness compared with unfractionated heparin (UFH) is uncertain. MATERIALS AND METHODS: This study investigated the safety and cost-effectiveness of enoxaparin in comparison to UFH for bridge therapy in 165 consecutive patients (57+/-11 years, 35% men) with MHV who underwent invasive dental procedures. RESULTS: This study included 75 patients treated with UFH-based bridge therapy (45%) and 90 patients treated with enoxaparin-based bridge therapy (55%). The bleeding risk of dental procedures and the incidence of clinical adverse outcomes were not significantly different between the UFH group and the enoxaparin group. However, total medical costs were significantly lower in the enoxaparin group than in the UFH group (p<0.001). After multivariate adjustment, old age (> or =65 years) was significantly associated with an increased risk of total bleeding independent of bridging methods (odds ratio, 2.51; 95% confidence interval, 1.15-5.48; p=0.022). Enoxaparin-based bridge therapy (beta=-0.694, p<0.001) and major bleeding (beta=0.296, p=0.045) were significantly associated with the medical costs within 30 days after dental procedures. CONCLUSION: Considering the benefit of enoxaparin in cost-effectiveness, enoxaparin may be more efficient than UFH for bridge therapy in patients with MHV who required invasive dental procedures.
Aged
;
Anticoagulants/*therapeutic use
;
Dentistry, Operative/*methods
;
Enoxaparin/therapeutic use
;
Female
;
*Heart Valve Prosthesis
;
Heparin, Low-Molecular-Weight/*therapeutic use
;
Humans
;
Male
;
Middle Aged
6.Primary Bilateral B-cell Renal Lymphoma: A Case Report and Review of the Literature.
Ki Nam SHIM ; Kyu Bok CHOI ; Seung Ki RYU ; Sa Yong PARK ; Ki Ryung PARK ; Eun Mi NAM ; Jin Hyuk CHOI ; Duck Hee KANG ; Kyun Il YOON ; Sun Hee SUNG
Korean Journal of Medicine 1997;52(4):565-569
Primary lymphoma of the kidney is rare, and in most cases is attributable to lymphomatous renal infilitration of systemic non-Hodgkin's lymphoma or an extension from an adjacent site of the disease. Since the renal parenchyma is not a lymphoid organ, the mechanism by which renal lymphoma occur remains poorly understood. We report here a case of primary bilateral B-cell renal lymphoma in 26-year-old man who was treated successfully with combination chemotherapy.
Adult
;
B-Lymphocytes*
;
Drug Therapy, Combination
;
Humans
;
Kidney
;
Lymphoma*
;
Lymphoma, Non-Hodgkin
7.Relationship between Clinical Outcomes and Superior Sagittal Sinus to Bone Flap Distance during Unilateral Decompressive Craniectomy in Patients with Traumatic Brain Injury: Experience at a Single Trauma Center.
Hyuk Ki SHIM ; Seung Han YU ; Byung Chul KIM ; Jung Hwan LEE ; Hyuk Jin CHOI
Korean Journal of Neurotrauma 2018;14(2):99-104
OBJECTIVE: This retrospective study was conducted to investigate the relationship between the superior sagittal sinus (SSS) to bone flap distance and clinical outcome in patients with traumatic brain injury (TBI) who underwent decompressive craniectomy (DC). METHODS: A retrospective review of medical records identified 255 adult patients who underwent DC with hematoma removal to treat TBI at our hospital from 2016 through 2017; of these, 68 patients met the inclusion criteria and underwent unilateral DC. The nearest SSS to bone flap distances were measured on postoperative brain computed tomography images, and patients were divided into groups A (distance ≥20 mm) and B (distance < 20 mm). The estimated blood loss (EBL) and operation time were evaluated using anesthesia records, and the time spent in an intensive care unit (ICU) was obtained by chart review. The clinical outcome was rated using the extended Glasgow Outcome Scale (GOS-E) at 3 and 6 months postoperatively. RESULTS: The male to female ratio was 15:2 and the mean subject age was 55.12 years (range, 18–79 years). The mean EBL and operation times were significantly different between groups A and B (EBL: 655.26 vs. 1803.33 mL, p < 0.001; operation time: 125.92 vs. 144.83 min, p < 0.001). The time spent in the ICU and GOS-E scores did not differ significantly between the groups. CONCLUSION: We recommend that when DC is indicated due to TBI, an SSS to bone flap distance of at least 20 mm should be maintained, considering the EBL, operation time, and other outcomes.
Adult
;
Anesthesia
;
Brain
;
Brain Injuries*
;
Decompressive Craniectomy*
;
Female
;
Glasgow Outcome Scale
;
Hematoma
;
Humans
;
Intensive Care Units
;
Male
;
Medical Records
;
Retrospective Studies
;
Superior Sagittal Sinus*
;
Trauma Centers*
8.Clinico-pathologic features in endometrial carcinoma by the histologic type.
Hyuk Jun WOO ; In Ho LEE ; Sei Jin PARK ; Won Ki HONG ; Tae Jin KIM ; Kyung Taek LIM ; Jae Uk SHIM ; Ki Heon LEE
Korean Journal of Gynecologic Oncology 2006;17(4):310-315
OBJECTIVE: The aim of this study was to correlate histologic type with the clinico-pathologic features of endometrial carcinoma. METHODS: A retrospective review was performed of 158 patients with endometrial cancer who had treated surgically at Cheil General Hospital between Jan. 2000 and Dec. 2003. Histologic findings after operation were divided two groups (endometrioid group vs. non-endometrioid group) then compared to each other groups. Clinico-pathologic factors were reviewed, compared and statistically analyzed. RESULTS: Endometrioid group was 112 cases (70.9%) and non-endometrioid group was 46 cases (29.1%). Non-endometrioid group was mucinous; 5 (3.2%), UPSC; 6 (3.8%), clear Cell; 2 (1.3%), mixed; 32 (20.3%), adenosquamous; 1 (0.6%). Non-endometrioid group showed older (p=0.0003) and higher proportion of menopausal women (p=0.0017) than Group 1. But menopause mean age were not diffent between two group. Abnormality in Pap smear and thickness of endometrium (TVS) were not diffent between two group. Non-endometrioid group were significantly associated with higher grade (p=0.0000), deeper myometrial invasion (p=0.0030), larger tumor size (p=0.0006), Lympho-vascular invasion (p=0.0486) and higher recurrence rate (p=0.0369) CONCLUSION: This study revealed non-endometrioid group was significantly associated with older age, menopause status, advanced pathologic features at surgical staging, and high recurrence rate.
Endometrial Neoplasms*
;
Endometrium
;
Female
;
Hospitals, General
;
Humans
;
Menopause
;
Mucins
;
Recurrence
;
Retrospective Studies
9.A prospective randomized study of cisplatin versus PEV(cisplatin, etoposide, vinblastine) chemotherapy in advanced non-small cell lung cancer.
Ki Hyeong LEE ; Won Ki KANG ; Joung Soon JUNG ; Sung Soo YOON ; Young Hyuk IM ; Jae Yong LEE ; Young Suk PARK ; Chang In SUH ; Dae Seog HEO ; Yung Jue BANG ; Young Soo SHIM ; Noe Kyeong KIM
Journal of the Korean Cancer Association 1992;24(2):256-267
No abstract available.
Carcinoma, Non-Small-Cell Lung*
;
Cisplatin*
;
Drug Therapy*
;
Etoposide*
;
Prospective Studies*
10.Development of the Single Nodular VX-2 Carcinoma Model in Rabbit Liver: Tissue Chip Implantation under Ultrasonographic Guidance.
Seong Jun YANG ; Hyung Jin SHIM ; Byung Kook KWAK ; Jong Beum LEE ; Kang Hyuk LEE ; Seung Hun RYU ; Ki Hyun KIM ; Seo Hyun KWAK
Journal of the Korean Radiological Society 2001;44(1):19-27
PURPOSE: To implant tissue chips in New Zealand rabbits, and thus redurce the frequency with which scattered VX2 carcinoma nodules and early metastasis develop in these animals. MATERIALS AND METHODS: VX2-carcinoma tissue chips of two different sizes were implanted under ultrasonographic guidance. In each of 12 New Zealand rabbits (group 1), there 1-mm tissue chips were implanted in the liver using an 18-gauge needle, and in the same way, one 3-mm chip with an added gelfoam pellet was implanted in the proximal lumen of the liver of each of ten other New Zealand rabbits (group 2). Three weeks after implantation, the animals underwent dvalphase CT scanning and were sacrificed, and the Number and size of tumor nodules, and metastasis were evaluated either macro-or microscopically. RESULTS: In ten rabbits in group I, a total of 21 nodules (16 in the liver, 5 in the peritoneal wall) were observed, which in nine rabbits in group 2, a total of ten nodules-all in the liver-were present. CT scans depicted tumor nodules in 50% of group-I rabbits, and in 29% those in group 2. Mean tumor diameter was 12 +/-9 mm in group 1 and 6.4 +/-3 mm in group 2. Histologic examination indicated the presence of nodular VX2 carcinoma, with varying degrees of central necrosis, a feature more prominent in group 2. CONCLUSION: To provide a well-localized tumor nodule in rabbit liver, tissue chip implantation of VX2 carcinoma, especially with added gelfoam, is a good alternative to intraparenchymal injection of tumor suspension.
Animals
;
Gelatin Sponge, Absorbable
;
Liver*
;
Necrosis
;
Needles
;
Neoplasm Metastasis
;
Rabbits
;
Tomography, X-Ray Computed