Alveolar Process ; Maxilla ; Osteotomy

Child ; Child, Preschool ; Cleft Lip ; Cleft Palate ; Congenital Abnormalities ; Consensus ; Humans ; Infant ; Leukocyte Count ; Male ; Palate ; Surgery, Oral

The purpose of this study is to examine the change of enzymeimmuno-assay for prostaglandinE2 in the synovial fluid lavage specimen of patients with mandibular fracture patients without condylar fracture. For this study, fourteen patients (eight males, six females) with mandibular fractures without condylar fracture was investigated to analyse the synovial fluid from upper temporomandibular joint cavities. Synovial fluid was collected from TMJ cavities of mandibular fracture patients before open reduction and after one week of open reduction, and then stored in liquid nitrogen tank after centrifuge. Two synovial fluid lavage samples of TMJs of 2 asymptomatic served as normal controls referred from other data. The concentrations of PGE2 were measured by use of PGE2 EIA system (Amersham). The following results were obtained: 1) In nine patients, the concentrations of PGE2 are lower after open reduction than before. 2) In three patients, the concentrations of PGE2 are higher after open reduction than before. 3) There was no statistical significant between the preoperative group and postoperative 7 days (p>0.05), but there was some difference between the two groups. In conclusion, the results suggest that PGE2 probably does not play as important role in the harm of TMJ.
Dinoprostone* ; Humans ; Male ; Mandibular Fractures* ; Nitrogen ; Synovial Fluid* ; Temporomandibular Joint* ; Therapeutic Irrigation

PURPOSE: To evaluate the relationship between the speed of enhancement of hepatic hemangiomas on gadolinium-enhanced MRI and ADC values by using various parameters, including the D, f, D* and ADC(fit) on intravoxel incoherent motion (IVIM) MR Imaging. MATERIALS AND METHODS: The institutional review board approved this retrospective study. A total of 47 hepatic hemangiomas from 39 patients were included (20 men and 19 women). The hemangiomas were classified into three types according to the enhancement speed of the hepatic hemangiomas on gadolinium-enhanced dynamic T1-weighted images: rapid (Type A), intermediate (Type B), and slow (Type C) enhancement. The D, f, D* and ADC(fit) values were calculated using IVIM MR imaging. The diffusion/perfusion parameters and ADC values were compared among the three types of hemangiomas. RESULTS: Both the ADC(fit) and D values of type C were significantly lower than those of type A (P = 0.0022, P = 0.0085). However, for the f and D*, there were no significant differences among the three types. On DWI with all b values (50, 200, 500 and 800 sec/mm2), the ADC values of type C were significantly lower than those of the type A (P < 0.012). For b values with 800 sec/mm2, the ADC800 values of the type C hemangiomas were significantly lower than those of type B (P = 0.0021). We found a negative correlation between hepatic hemangioma enhancement type and ADC50 (rho= -0.357, P = 0.014), ADC200 (rho= -0.537, P = 0.0001), ADC500 (rho= -0.614, P = 0.0001), and ADC800(rho= -0.607, P = 0.0001). Therefore, four ADC values of ADC50, ADC200, ADC500, and ADC800 were decreased with decreasing enhancement speed. CONCLUSION: Hepatic hemangiomas had variable ADCs according to the type of enhancement, and the reduced ADCs in slowly enhancing hemangiomas may be related to the reduced pure molecular diffusion (D).
Diffusion ; Ethics Committees, Research ; Hemangioma* ; Humans ; Magnetic Resonance Imaging* ; Male ; Retrospective Studies

Although various neoplasms may develop in the ventricular system, glioblastomas are rare. An 80-year-old woman visited our hospital with intractable headache related to a right ventricular large mass, which exhibited heterogeneous enhancement involving the body, trigone, and occipital horn of the right lateral ventricle on MRI. The mass was diagnosed as glioblastoma multiforme on surgical pathology. Herein, the authors present a case and review the existing literature with regarding to incidence, pathophysiology, prognostic factors, imaging and pathologic findings of intraventricular glioblastoma multiforme.

PURPOSE: A pulsed arterial spin labeling (PASL) signal usually depends on several parameters. The objective of this study was to determine the optimal parameters using simulation for perfusion signals of PASL magnetic resonance imaging (MRI). MATERIALS AND METHODS: Perfusion signals, DeltaM/M(0b), derived from the Bloch equation were evaluated in regard to the four most important parameters in PASL MRI: the tissue-to-blood coefficient (lambda), the longitudinal relaxation time of blood (T(1b)), the arterial transit delay from the application of tag (deltat), and the magnetic field strength (B0). The simulation was conducted with Mathematica software. RESULTS: First, perfusion signals differed depending on the value of lambda in brain tissue. The maximum signal, DeltaM/M(0b) = 0.390, was obtained at an inversion time (TI) = 1.53 sec for gray matter on 3T MRI. Second, perfusion signals were reduced with increasing deltat. The maximum signal, DeltaM/M0b = 0.526, was obtained at TI = 2.1 sec for deltat = 0.5 sec. Finally, perfusion signals increased with increasing B0. The maximum signal, DeltaM = 1.15, was obtained at TI = 1.52 sec for 3T MRI. CONCLUSION: We reported that the optimized TI values were obtained to provide the highest PASL signals. It is very important that optimized TI values be used to obtain high-quality perfusion signals using PASL MRI.
Brain ; Magnetic Fields ; Magnetic Resonance Imaging ; Perfusion ; Relaxation

PURPOSE: This study aimed to compare cerebral hemispheric volumes between pharmacologic treatment and supportive management of patent ductus arteriosus (PDA). METHODS: The study was conducted retrospectively. The subjects of period 1 group were very low birth weight infants whose PDA were treated with pharmacologic closure. Period 2 group were treated with supportive management. Regional brain volumes measured using magnetic resonance imaging were compared between the two groups. RESULTS: total of 12 infants were included. Their median gestational age was 27⁺⁶ (range: 24⁺¹–31⁺¹) weeks and birth weight was 1,065 g (range: 690–1,380). Between the two groups, there was no difference in Apgar score, incidence of bronchopulmonary dysplasia, necrotizing enterocolitis, and culture proven sepsis. The regional brain volumes such as gray matter (Period 1 group, 76,833 mm³ [55,759–100,388] vs. Period 2 group, 79,870 mm³ [59,957–113,018], P=0.59), white matter (82,993 mm³ [63,130–121,311] vs. 92,576 mm³ [77,200–104,506], P=0.18), cerebrospinal fluid (17,167 mm³ [9,279–22,760] vs. 14,348 mm³ [7,018–27,604], P=0.94), basal ganglia (2,065 mm³ [1,697–2,482] vs. 2,306 mm³ [2,065–3,009], P=0.18), and cerebellum (18,374 mm³ [14,843–24,657] vs. 18,096 mm³ [16,134–23,627], P=0.94) were not different between the two groups. CONCLUSION: Regional brain volumes were not different between pharmacological and conservative treatment in infants with PDA. Further wellcontrolled studies are required to evaluate the advantages or disadvantages of supportive management without pharmacologic treatment of PDA.
Apgar Score ; Basal Ganglia ; Birth Weight ; Brain* ; Bronchopulmonary Dysplasia ; Cerebellum ; Cerebrospinal Fluid ; Ductus Arteriosus, Patent* ; Enterocolitis, Necrotizing ; Gestational Age ; Gray Matter ; Humans ; Ibuprofen* ; Incidence ; Infant* ; Infant, Newborn ; Infant, Premature ; Infant, Very Low Birth Weight* ; Magnetic Resonance Imaging ; Pilot Projects* ; Retrospective Studies ; Sepsis ; White Matter

No abstract available.
Arteries ; Intracranial Arteriosclerosis

PURPOSE: Nodular lesions of the thyroid gland, composed predominantly of Hürthle cells, are so rare as to be difficult for pathologists to interpret properly and, consequently, for surgeons to treat appropriately. Our intent in evaluating these lesions was to try to establish pathologic and clinical criteria that could be used to differentiate more accurately between malignant and benign tumors. METHODS: We retrospectively evaluated 5 patients presenting with Hürthle cell tumors over the past 10 years. We focused on the clinicopathological analysis correlated with the tumor size, the type of operation and the prognosis. RESULTS: Five female patients were included in the study, their average age was 48.8 years (19~69 years). One case was carcinoma and the other 4 were adenomas. Average size of the tumor was 3.34 cm in diameter. Total thyroidectomy was performed in two cases including the carcinoma case. None of them died as a result of the disease, nor had a recurrence. No preoperative study was useful in differentiating between malignancy and benignancy. CONCLUSION: Many more cases need to be evaluated to determine the exact biological behavior of the Hürthle cell tumor of the thyroid gland. Clinical and pathological factors are required for surgeons to decide the type of operation appropriate in order to avoid compromising the therapeutic goals. We recommend total thyroidectomy for tumors with the intraoperative frozen section raising the suspicion of malignancy and for those with diameters over 2.5 cm.
Adenoma ; Adenoma, Oxyphilic* ; Female ; Frozen Sections ; Humans ; Prognosis ; Recurrence ; Retrospective Studies ; Surgeons ; Thyroid Gland* ; Thyroidectomy

Purpose: This study aimed to propose an effective end-to-end process in medical imaging using an independent task learning (ITL) algorithm and to evaluate its performance in maxillary sinusitis applications. Materials and Methods: For the internal dataset, 2122 Waters’ view X-ray images, which included 1376 normal and 746 sinusitis images, were divided into training (n=1824) and test (n=298) datasets. For external validation, 700 images, including 379 normal and 321 sinusitis images, from three different institutions were evaluated. To develop the automatic diagnosis system algorithm, four processing steps were performed: 1) preprocessing for ITL, 2) facial patch detection, 3) maxillary sinusitis detection, and 4) a localization report with the sinusitis detector. Results: The accuracy of facial patch detection, which was the first step in the end-to-end algorithm, was 100%, 100%, 99.5%, and 97.5% for the internal set and external validation sets #1, #2, and #3, respectively. The accuracy and area under the receiver operating characteristic curve (AUC) of maxillary sinusitis detection were 88.93% (0.89), 91.67% (0.90), 90.45% (0.86), and 85.13% (0.85) for the internal set and external validation sets #1, #2, and #3, respectively. The accuracy and AUC of the fully automatic sinusitis diagnosis system, including site localization, were 79.87% (0.80), 84.67% (0.82), 83.92% (0.82), and 73.85% (0.74) for the internal set and external validation sets #1, #2, and #3, respectively. Conclusion ITL application for maxillary sinusitis showed reasonable performance in internal and external validation tests, compared with applications used in previous studies.