No abstract available.
Humans ; Hypoglycemia* ; Infant* ; Infant, Newborn* ; Iron*

1. Author has reviewed 41 cases of bladder tumor treated at Urological Department of Seoul National University during the period of 3 years and 9 months from August 1954 to May 1958. The clinical studies on above cases revealed following findings. 2. There were no specific relationships between family histories, past histories and occupations of patients and bladder tumor. 3. Among the series, 3 were recurrent, another 3 cases were metastatic while the rest of cases (35) were primary tumors. 4. 21 cases were treated as the in-patients, 11 cases out of 21 cases were treated by surgical procedures and 10 cases were found to be contraindicated for the surgical procedure because of the advancement of the malignancy. 5. There were 31 males and 9 females, the ratio being 4:1. 6. The youngest age was 26 and oldest age was 76. 80.5% of series ranged from 40 years of age to 69 years. 7. The 87.8% of chief complaints were hematuria, 78.0% were painful urination,37.1% were frequency. 8. The predominant initial symptom was hematuria among 78.0% of cases. 9. Since the time lapsed from the initial onset to first hospital visit was 6 months to 2 years in 48.7% of series. It showed marked difference from the fact that 43% of series reported by Drinker in the America visited hospital within 3 months from the initial onset. 10. According to cystoscopic findings, there were 19 cases of non-infiltrating type and 19 cases of infiltrating type while 3 metastatic type, 2 solitary and 20 multiple cases were present 11. As to the localization of tumor, 46.3% of series were on lateral wall of the bladder. 12. Out of 11 cases treated surgically 3 cases were treated by total cystectomy combined with ureterosigmoidostomy, 4 cases were electro-coagulation and 4 cases were partial resection of the bladder. 13. It seems to be feasible that estrogen could be administrated per os as a conservative procedure for an inoperable case and also estrogen could be combined as a pre-and post-operative medication for a surgical case.
Americas ; Cystectomy ; Estrogens ; Female ; Hematuria ; Humans ; Male ; Occupations ; Seoul ; Urinary Bladder Neoplasms* ; Urinary Bladder*

No abstract available.
Laparoscopy* ; Pelvic Pain*

The pupose of this study is to verify the role of urinary sodium in transient renal acidification defect which frequently combine acute infantile gastroenteritis. We studied on twenty-five infants, 2month to 36 month of age, during the 4 month period, from August, 1991 to December, 1991. The patients had acidosis for a mean of 3 days and sixty urine samples were collected during this period. The mean pH of 23 rine samples with sodium concentration<10 mmol/L was significantly higher than pH of 37 samples with sodium concentration<10 mmol/L, We separately analyzed 15 urine samples collected during metabolic acidosis after completion. of rehydration. The result was that a urinary acidification defent was observed in the urine samples with low sodium concentration but not in the sodium rich samples. We concluded that impaired urinary acidification defect is frequently during metabolic acidosis in infants with acute gastroenteritis and results from a sodium deficit rather than from transient distal renal tublur acidosis.
Acidosis ; Fluid Therapy ; Gastroenteritis* ; Humans ; Hydrogen-Ion Concentration ; Infant ; Sodium*

BACKGROUND: The angiotensin-converting enzyme(ACE) plays an important role in cardiovascular disease by production of angiotensin and degradation of bradykinin. Cloning of ACE gene revealed an insertion/deletion(I/D) polymorphism according to the presence/absence of a 287 base pair fragment in the 16th intron of ACE gene, and the ACE polymophism was associated with ACE activity. The genotype DD was identified as a risk factor for myocardial infarction in several studies. We analyzed the ACE I/D polymorphism in 62 patients with myocardial infarction and 67 normal subjects. METHODS: Genomic DNA from peripheral blood was amplified by polymerase chain reaction and characterized by three ACE genotypes; two insertion alleles(genotype II), two deletion alleles(genotype DD) and heterogenous alleles(genotype ID). ACE activity was determined by spectrophotometric method utilizing the synthetic substrate. RESULTS: There was no significant difference in ACE polymorphism between patients and normal subjects. But, the frequency of genotype DD was significantly increased in the low-risk group of patients compared with the high-risk group. The multi-vessel disease was more strongly associated with genotype DD, but there was no statistical significance. The ACE activity was strongly associated with ACE polymorphism with the activity being highest in genotype DD. There was no significant difference between patients and control subjects of the same genotype. CONCLUSION: There was no significant difference in ACE polymorphism between patients and normal subjects. The frequencies for genotype II, ID, DD were 0.328, 0.537, 0.134, respectively in normal subjects. There was high frequency of genotype II compared with Caucasians. A deletion polymorphism(genotype DD) may increase the risk for myocardial infarction in lowrisk group, and the serum ACE activity was correlated with three genotypes.
Angiotensins ; Base Pairing ; Bradykinin ; Cardiovascular Diseases ; Clone Cells ; Cloning, Organism ; DNA ; Genotype ; Humans ; Introns ; Myocardial Infarction* ; Polymerase Chain Reaction ; Risk Factors

No abstract available.

Leiomyoblastoma is uncommon and has been known as a neoplasm of smooth muscle origin. However, with recent pragress in immunohistochemical staining techniques, many clinicopathological discrepancies have been pointed out about the origin of leiomyoblastoma. We present here a case of gastric leiomyoblastoma did not expressed desmin and neuron specific enolase, and was thought to be of unknown derivation.
Desmin ; Leiomyoma, Epithelioid* ; Muscle, Smooth ; Phosphopyruvate Hydratase

Leiomyoblastoma is uncommon and has been known as a neoplasm of smooth muscle origin. However, with recent pragress in immunohistochemical staining techniques, many clinicopathological discrepancies have been pointed out about the origin of leiomyoblastoma. We present here a case of gastric leiomyoblastoma did not expressed desmin and neuron specific enolase, and was thought to be of unknown derivation.
Desmin ; Leiomyoma, Epithelioid* ; Muscle, Smooth ; Phosphopyruvate Hydratase

No abstract available.

No abstract available.