1.A Study on Left Ventricular Function Evaluation with Radionuclide Angiography in Coronary Artery Disease.
Hyuck Moon KWON ; Hyun Seung KIM ; Hyo Jin PARK ; Jae Soon LEE ; Sung Hyun WOO
Korean Circulation Journal 1987;17(1):55-63
A number of noninvasive technics have been advocated as reflecting left ventricular performance. These methods include systolic time intervals, echocardiography and imaging of the left ventricular chamber with radionuclides during systole and diastole. Radionuclide evaluation of left ventricular function by means of the gamma camera and gating currently appears to be the most reliable noninvasive method for approximating angiographic evaluation of left ventricular performance. Utilizing the radionuclide angiography, we measured the left ventricular function in 19 normal healthy control, 60 patients with coronary artery diseases 7 patients with dilated cardiomyopathy, 5 patients with hypertension. 1) Left ventricular ejection fraction decreased in 12 patients with anterior myocardial infarction (39.9+/-11.6%), 17 patients with inferior myocardial infarction (49.9+/-8.4%) and 7 patients with dilated cardiomyopathy (19.0+/-5.8%), and there was a statistically significant difference compared with 19 normal control group (63.5+/-8.2%)(p<0.005). However there were no statistically significant difference between normal control group, patients with hypertension (58.8+/-7.6%) and patients with angina pectoris (60.1+/-6.5%). 2) Left ventricular ejection fraction decreased in both anterior and inferior myocardial infarction, and there was a statisically significant difference between both groups (p<0.01). All 13 patients with acute myocardial infarction had abnormal LVEF (40.5+/-9.1%) whcih was significantly lower than that of 16 patients with old myolardial infarction (50.1+/-10.5%)(p<0.01).
Angina Pectoris
;
Cardiomyopathy, Dilated
;
Coronary Artery Disease*
;
Coronary Vessels*
;
Diastole
;
Echocardiography
;
Gamma Cameras
;
Humans
;
Hypertension
;
Infarction
;
Inferior Wall Myocardial Infarction
;
Myocardial Infarction
;
Radioisotopes
;
Radionuclide Angiography*
;
Stroke Volume
;
Systole
;
Ventricular Function, Left*
2.Effect of cumulus cells on the development of one cell stage mouse zygotes.
Hyuck Dong HAN ; Jang Yoen KWON ; Sang Won HAN ; Young Jin LEE ; Dong Soo CHA ; Dae Hyun KIM
Korean Journal of Obstetrics and Gynecology 1991;34(4):554-558
No abstract available.
Animals
;
Cumulus Cells*
;
Mice*
;
Zygote*
3.Effect of cell stage on development of mice embryo after cryopresservation and thawing.
Hyuck Dong HAN ; Young Dae KIM ; Sung Wook SHON ; Jang Yeon KWON ; Young Jin LEE ; In Bae CHUNG ; Dong Soo CHA
Korean Journal of Fertility and Sterility 1993;20(2):161-164
No abstract available.
Animals
;
Embryonic Structures*
;
Mice*
4.A case of amniotic band syndrome.
Kee Myoung UM ; Hae Kyoung LEE ; Jang Yeon KWON ; Young Jin LEE ; Hyuck Dong HAN ; Dae Hyun KIM
Korean Journal of Obstetrics and Gynecology 1992;35(12):1839-1843
No abstract available.
Amniotic Band Syndrome*
;
Infant, Newborn
5.New Provisional Classification of Juvenile Idiopathic Arthritis Applying Rheumatoid Factor and Antinuclear Antibody
Hyuck Jin KWON ; Myung Hoon BANG ; Kwang Nam KIM
Journal of Rheumatic Diseases 2018;25(1):34-46
OBJECTIVE: Previous classification systems for juvenile idiopathic arthritis (JIA) were based on the number of joints involved and did not categorize homogenous disease entities. Therefore, JIA patients were reclassified retrospectively by applying rheumatoid factor (RF) and antinuclear antibody (ANA), which have been proven to constitute a homogenous disease entity. METHODS: The medical records of JIA patients were investigated retrospectively and reclassified into six categories using the new provisional classification. The nomenclature was based on Dr. Martini's proposal in the 23rd European Paediatric Rheumatology Congress (2016) at Genoa, Italy. New categories included systemic JIA (sJIA), RF-positive JIA (RF-JIA), early-onset ANA-positive JIA (eoANA-JIA), enthesitis/spondylitis-related JIA (ESR-JIA), “other JIA”, and “unclassified JIA”. RESULTS: Of a total of 262 JIA patients, 71 (27.1%) were reclassified as sJIA, 31 (11.8%) as RF-JIA, 22 (8.4%) as eoANA-JIA, 63 (24.0%) as ESR-JIA, 65 (24.8%) as “other JIA”, and 10 (3.8%) as “unclassified JIA”. A comparison of RF-JIA, eoANA-JIA, and ESR-JIA revealed significant differences in the gender ratio, age of disease onset, and the cumulative number and type of joints involved among the three groups. “Other JIA” comprised a significant proportion (24.8%) and warrants the need for further classification. The characteristics of the RF-positive patients were comparable to those of the anti-cyclic citrullinated peptide antibody-positive patients. The ANA positivity was lower (28.2%) than that in Western studies but showed similar clinical features. CONCLUSION: This is the first study applying RF and ANA to classify JIA without considering the joint counts. The six new categories include sJIA, RF-JIA, eoANA-JIA, ESR-JIA, “other JIA,” and “unclassified JIA”.
Antibodies, Antinuclear
;
Arthritis, Juvenile
;
Classification
;
Humans
;
Italy
;
Joints
;
Medical Records
;
Retrospective Studies
;
Rheumatoid Factor
;
Rheumatology
6.Pemphigus Foliaceus Associated with Psoriasis during the Course of Narrow-Band UVB Therapy: A Simple Coincidence?.
Hyuck Hoon KWON ; In Ho KWON ; Jin Ho CHUNG ; Jai Il YOUN
Annals of Dermatology 2011;23(Suppl 3):S281-S284
Although psoriasis and bullous diseases are considered to be completely different disease entities, the literature has reported a few cases of psoriasis associated with bullous diseases, most of which are bullous pemphigoid. In limited cases, pemphigus foliaceus has also been reported in association with psoriasis. In most of them, pemphigus lesions usually developed on an untreated patient with a chronic history of psoriasis. Herein, we report a case of 53-year-old male with a chronic history of psoriasis who first developed generalized erosive lesions after 26 cycles of narrow-band ultraviolet B (NBUVB) therapy. A diagnosis of pemphigus foliaceus was made based on skin biopsy and direct immunofluorescence assay. Pemphigus lesions were well controlled with combination therapy of oral steroid and azathioprine. This is the first case where pemphigus foliaceus co-occurred with psoriasis during NBUVB therapy.
Azathioprine
;
Biopsy
;
Fluorescent Antibody Technique, Direct
;
Humans
;
Male
;
Middle Aged
;
Pemphigoid, Bullous
;
Pemphigus
;
Psoriasis
;
Skin
7.Anterior Spinal Artery Syndrome Associated With Cervical Spinal Stenosis.
Jong Ho PARK ; Ki Ran KWON ; Byung Chul LEE ; Suk Beom KWON ; Hwi Chul CHOI ; Jin Hyuck KIM
Journal of the Korean Geriatrics Society 1997;1(2):155-160
BACKGROUND: The anterior spinal artery infarction constitutes a classical syndrome of vascular myelopathy. The causes of the anterior spinal artery syndrome are various, but most episode probably occur as the result of atherosclerosis or dissection of the aorta and its branches. However, few cases reported developed with spinal structural abnormalities. CASE: A 65-year-old man presented with sudden paraparesis. There was no evidence of hypertension, diabetes and smoking. Motor weakness was more prominent on the left side and progressed. Loss of pain and temperature senses were shown at the level of 71 with preservation of touch, joint perception and vibration senses. The DTR's of legs were depressed and extensor toe signs were presented. A C-spine MRI showed high signal intensity on 72 weighted image and low signal on 71 weighted image(C6-71) with cervical spinal stenosis at the C4-C7 spinal level and mild cervical disc protrusion (C6-C7, C7-T1). After three months later, follow up cervical MRI showed somewhat decreased size of high signal intensity on 72 weighted image and more prominent low signal on 71 image. DISCUSSION: In our case, we could not find any usual cause of anterior spinal artery infarction. However only cervical spinal stenosis associated with mild cervical disc protrusion was present. In stenotic cervical canal, the anterior spinal artery can be more vulnerable to extrinsic compression and the infarction may early develop with insignificant trigger event, such as disc protrusion. We concluded that the ischemic change of anterior two thirds of cervical spinal cord might develop due to the compression of the anterior spinal artery by cervical stenosis and mild cervical intervertebral disc protrusion.
Aged
;
Anterior Spinal Artery Syndrome*
;
Aorta
;
Arteries
;
Atherosclerosis
;
Constriction, Pathologic
;
Follow-Up Studies
;
Humans
;
Hypertension
;
Infarction
;
Intervertebral Disc
;
Joints
;
Leg
;
Magnetic Resonance Imaging
;
Paraparesis
;
Smoke
;
Smoking
;
Spinal Cord
;
Spinal Cord Diseases
;
Spinal Stenosis*
;
Toes
;
Vibration
8.Acute Pulmonary Embolism Associated with Transposition of the Inferior Vena Cava in a 14-year-old Boy.
Hyuck Jin KWON ; Jin Shik SHIN ; Hyun Sook KIM ; Kwanseop LEE ; Sung Hye KIM
Journal of the Korean Society of Emergency Medicine 2017;28(6):676-681
Idiopathic venous thromboembolism (VTE) and pulmonary embolism (PE) are relatively infrequent in the pediatric population but are almost always associated with an underlying disease or risk factors, such as congenital or acquired coagulation abnormalities, autoimmune disorders, or malignancies. In the pediatric emergency department, VTE, and particularly, PE, are often less considered in differential diagnoses because of their low incidence. On the other hand, a delayed diagnosis can result in serious morbidity and mortality. Therefore, even if there are no well-known risk factors, it is important to consider the possibility of PE, whenever there are suspicious symptoms and signs. The transposition of the inferior vena cava (IVC) is one of the major anatomical variants among the spectrum of IVC malformations. Although most IVC malformations are clinically silent and are discovered incidentally on radiographs, they are associated with PE in rare cases. In the pediatric population, no cases of transposition of the IVC that was discovered by acute PE have been reported. We report a case of acute PE associated with a transposition of the IVC in a 14-year-old boy without intra-cardiac anomalies or coagulation abnormalities.
Adolescent*
;
Delayed Diagnosis
;
Diagnosis, Differential
;
Emergency Service, Hospital
;
Hand
;
Humans
;
Incidence
;
Male*
;
Mortality
;
Pulmonary Embolism*
;
Risk Factors
;
Vascular Malformations
;
Vena Cava, Inferior*
;
Venous Thromboembolism
9.Left ventricular dimensions and function during dynamic exercise of athletes by echocardiography.
Young Jun KIM ; Seong Jin BAE ; Hyuck LEE ; Won Suk AN ; Hyuk Chan KWON ; Moo Hyun KIM ; Young Dae KIM ; Jong Seong KIM
Journal of the Korean Society of Echocardiography 1993;1(1):71-87
No abstract available.
Athletes*
;
Echocardiography*
;
Humans
10.Bilateral Putaminal Hemorrhage with Cerebral Edema in Hyperglycemic Hyperosmolar Syndrome.
Soo Jin CHO ; Tae Kyoung WON ; Seung Ju HWANG ; Joong Hyuck KWON
Yonsei Medical Journal 2002;43(4):533-535
Bilateral putaminal hemorrhages rarely occur simultaneously in hypertensive patients. The association of intracerebral hemorrhage with cerebral edema (CE) has been rarely reported in diabetic patients. We present a patient with bilateral putaminal hemorrhage (BPH) and CE during the course of hyperglycemic hyperosmolar syndrome (HHS). A 40-year-old man with a history of diabetes mellitus and chronic alcoholism was admitted with acute impaired mentality. His blood pressure was within the normal range on admission. Laboratory results revealed hyperglycemia and severe metabolic acidosis without ketonuria. After aggressive treatment, plasma sugar fell to 217 mg/dl, but brain CT showed BPH and diffuse CE. Our case demonstrated that HHS should be considered as a cause of BPH with CE. Initial brain imaging study may be recommended for patients with diabetic coma.
Adult
;
Brain/pathology
;
Brain Edema/*etiology
;
Case Report
;
Human
;
Hyperglycemic Hyperosmolar Nonketotic Coma/*complications
;
Male
;
Putaminal Hemorrhage/*etiology
;
Tomography, X-Ray Computed