The management of infectious intracranial aneurysm, either by antibiotics alone or by surgery plus antibiotic therapy, remains controversal. Some authors have recommended initial treatment with antibiotics, plus serial angiography, and consider surgery only in cases where aneurysm enlargement during antibiotic treatment or persistence after treatment is documented. Due to the unpredictable rebleeding rate and high morbidity and mortality rate associated with rebleeding, others have argued for prompt surgical intervention. We report a case of surgically treated infectious intracranial aneurysm located distal to the trifurcation of the right middle cerebral artery. During the course of high-dose antibiotic therapy, rupture and rapid enlargement occurred ; after the operation, the patient underwent cardiac surgery and is at present in good health.
Aneurysm ; Angiography ; Anti-Bacterial Agents ; Humans ; Intracranial Aneurysm* ; Middle Cerebral Artery ; Mortality ; Rupture ; Thoracic Surgery

In a series of 43 patients with intracranial meningioma, we retrospectively analysed factors influencing the development of peritumoral brain edema(PTBE). The extent of this was measured by the Edema Index(EI), obtained from the size of the meningioma and associated PTBE on a T2-weighted magnetic resonance image. We evaluated the relationship between EI and certain factors that may play a role in the development of PTBE ; namely age, size, location, and histology of the tumor, and its vascular supply(intrinsic cerebral artery or meningeal artery). Tumors in the frontal and sphenoid ridge regions tended to be associated with more extensive PTBE than these in the parietal, occipital, and infratentorial regions(p<0.05). In particular, the extent of infratentorial meningioma-associated PTBE tended to be slight. Histologically, PTBE associated with meningotheliomatous and transitional meningiomas tended to be more extensive than that associated with the fibroblastic meningiomas(p<0.05). On angiography, it was seen that for meningiomas supplied by intrinsic cerebral artery(internal carotid or veterbral artery only, or in conjunction with the meningeal artery), correlation with severe PTBE was higher than for those supplied by the meningeal artery only(p<0.05). We concluded, therefore, that location, histology, and vascular supply from the intrinsic cerebral arteries were the factors influencing PTBE.
Angiography ; Arteries ; Brain Edema* ; Brain* ; Cerebral Arteries ; Edema ; Fibroblasts ; Humans ; Meningeal Arteries ; Meningioma ; Rabeprazole ; Retrospective Studies