2.The investigation of pathologic oxygen supply dependency.
Chinese Journal of Pediatrics 2003;41(2):152-154
3.Hypothermia-induced acute kidney injury in an elderly patient.
Hyun Ju YOON ; Mun Chul KIM ; Jae Woo PARK ; Min A YANG ; Cheon Beom LEE ; In O SUN ; Kwang Young LEE
The Korean Journal of Internal Medicine 2014;29(1):111-115
Hypothermia, defined as an unintentional decline in the core body temperature to below 35degrees C, is a life-threatening condition. Patients with malnutrition and diabetes mellitus as well as those of advanced age are at high risk for accidental hypothermia. Due to the high mortality rates of accidental hypothermia, proper management is critical for the wellbeing of patients. Accidental hypothermia was reported to be associated with acute kidney injury (AKI) in over 40% of cases. Although the pathogenesis remains to be elucidated, vasoconstriction and ischemia in the kidney were considered to be the main mechanisms involved. Cases of AKI associated with hypothermia have been reported worldwide, but there have been few reports of hypothermia-induced AKI in Korea. Here, we present a case of hypothermia-induced AKI that was treated successfully with rewarming and supportive care.
Acute Kidney Injury/*etiology/therapy
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Aged
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Humans
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Hypothermia/*complications/therapy
;
Male
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*Rewarming
4.A Clinical Observation on l0 Cases of Anatrophic Nephrolithotomy.
Korean Journal of Urology 1987;28(6):808-814
The surgical intervention of renal staghorn calculi was performed in 9 patients(lOkidneys) who had undergone anatrophic nephrolithotomy with in situ hypothermia. admitted to the Department of Urology, HaniI Hospital, during four years periods from June, 1982 to May, 1986. This operation technique is simple, easy but uneventful recoveries followed only in a small group. The results were summarized as followings : l. Postoperative hospitalizations were 13.1 days(ranged from 8 to 21). 2. Operating time required 194.5 minutes with mean time(ranged from 150 to 230). 3. Renal artery clamping time required 36.4 minutes with mean time(ranged from 23 to 65). 4. Blood loss during operation was 875ml on the average loss(ranged from 350 to l400). 5. Postoperative complications were nephrectomy l case, pneumothorax l case, deep vein thrombosis l cases remained stone 3 cases.
Calculi
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Constriction
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Hospitalization
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Hypothermia
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Nephrectomy
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Pneumothorax
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Postoperative Complications
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Renal Artery
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Urology
;
Venous Thrombosis
5.Intraoperative body temperature and emergence delirium in elderly patients after non-cardiac surgery: A secondary analysis of a prospective observational study.
Guojun WANG ; Shuting HE ; Mengyao YU ; Yan ZHANG ; Dongliang MU ; Dongxin WANG
Chinese Medical Journal 2023;136(19):2330-2339
BACKGROUND:
Emergence delirium (ED) is a kind of delirium that occured in the immediate post-anesthesia period. Lower body temperature on post-anesthesia care unit (PACU) admission was an independent risk factor of ED. The present study was designed to investigate the association between intraoperative body temperature and ED in elderly patients undergoing non-cardiac surgery.
METHODS:
This study was a secondary analysis of a prospective observational study. Taking baseline body temperature as a reference, intraoperative absolute and relative temperature changes were calculated. The relative change was defined as the amplitude between intraoperative lowest/highest temperature and baseline reference. ED was assessed with the confusion assessment method for intensive care unit at 10 and 30 min after PACU admission and before PACU discharge.
RESULTS:
A total of 874 patients were analyzed with a mean age of 71.8 ± 5.3 years. The incidence of ED was 38.4% (336/874). When taking 36.0°C, 35.5°C, and 35.0°C as thresholds, the incidences of absolute hypothermia were 76.7% (670/874), 38.4% (336/874), and 17.5% (153/874), respectively. In multivariable logistic regression analysis, absolute hypothermia (lowest value <35.5°C) and its cumulative duration were respectively associated with an increased risk of ED after adjusting for confounders including age, education, preoperative mild cognitive impairment, American Society of Anesthesiologists grade, duration of surgery, site of surgery, and pain intensity. Relative hypothermia (decrement >1.0°C from baseline) and its cumulative duration were also associated with an increased risk of ED, respectively. When taking the relative increment >0.5°C as a threshold, the incidence of relative hyperthermia was 21.7% (190/874) and it was associated with a decreased risk of ED after adjusting above confounders.
CONCLUSIONS:
In the present study, we found that intraoperative hypothermia, defined as either absolute or relative hypothermia, was associated with an increased risk of ED in elderly patients after non-cardiac surgery. Relative hyperthermia, but not absolute hyperthermia, was associated with a decreased risk of ED.
REGISTRATION
Chinese Clinical Trial Registry (No. ChiCTR-OOC-17012734).
Humans
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Aged
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Body Temperature
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Emergence Delirium
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Hypothermia
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Postoperative Complications/epidemiology*
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Prospective Studies
6.Surgical Correction of Total Anomalous Pulmonary Venous Connection without Total Circulatory Arrest.
Won Kyung HAN ; Joon Yong CHO ; Jong Tae LEE ; Kyu Tae KIM ; Bong Hyun CHANG ; Eung Bae LEE
The Korean Journal of Thoracic and Cardiovascular Surgery 2006;39(1):12-17
BACKGROUND: Circulatory arrest under deep hypothermia is an important auxiliary means for surgical correction of total anomalous pulmonary venous connection (TAPVC). However, cardiac operations under deep hypothermic circulatory arrest are associated with the risk of post-arrest neurologic abnormalities. The purpose of this study is to evaluate the results of the surgical correction of total anomalous pulmonary venous connection without the total circulatory arrest. MATERIAL AND METHOD: Between April 2000 and October 2004, hospital records of 10 patients were reviewed retrospectively. RESULT: The locations for abnormal anatomical connections were supracardiac in 7 cases, cardiac in 1 case, and infracardiac in 2 cases. The mean cardiopulmonary bypass time and aorta cross clamp time were 116.8+/-40.7 and 69.5+/-24.1 minutes. There was no surgical mortality. Postoperative complications were post-repair pulmonary venous stenosis in 1 case, pneumonia in 1, pneumothorax in 1, wound infection in 1, and diaphragmatic paralysis in 1. All patients without pulmonary venous stenosis were in NYHA class I at mean follow-up of 16.6 months (3~49 months) CONCLUSION: We could obtain excellent results by repair without the total circulatory arrest for total anomalous pulmonary venous connection.
Aorta
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Cardiopulmonary Bypass
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Circulatory Arrest, Deep Hypothermia Induced
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Constriction, Pathologic
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Follow-Up Studies
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Hospital Records
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Humans
;
Hypothermia
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Mortality
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Pneumonia
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Pneumothorax
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Postoperative Complications
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Respiratory Paralysis
;
Retrospective Studies
;
Wound Infection
7.Research progress of acute coagulopathy of trauma-shock.
Chinese Journal of Traumatology 2015;18(2):95-97
Acute coagulopathy of trauma-shock (ACoTS) occurs in 25% of patients with severe trauma in the early phase, and the mortality of those patients is four-fold higher than patients without coagulopathy. The pathophysiology of this complicated phenomenon has been focused on in recent years. Tissue injury and hypoperfusion, activated protein C and Complements play important roles in the early phase after trauma. While the use of blood products, hypothermia, acidosis and inflammation are the main mechanism in late phase. Supplementing coagulation factors and platelets to improve ACoTS are inefficient. Only positive resuscitation from shock and improving tissue hypoperfusion have expected benefits.
Blood Coagulation Disorders
;
etiology
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Complement System Proteins
;
physiology
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Disseminated Intravascular Coagulation
;
etiology
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Humans
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Hypothermia
;
complications
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Inflammation
;
complications
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Protein C
;
physiology
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Shock, Traumatic
;
complications
10.A Case of Hypothermia Combined with Systemic Lupus Erythematosus.
Moon Hee YANG ; Won PARK ; Sung Kwon BAE ; Sung Soo KIM ; Yong Hwan LEE ; Kyung Wook LEE ; Jung Soo SONG
The Korean Journal of Internal Medicine 2001;16(1):44-46
Systemic lupus erythematosus(SLE) is a prototypic autoimmune disease affecting various organ systems. Hypothermia is a rare manifestation of SLE. We experienced a case of SLE combined with hypothermia. A 36-year-old woman, who had been diagnosed as SLE 3 days before admission, admitted complaining of mental confusion. After admission, her body temperature, initially 36.1 degree C, became 32.6 degree C. Her core body temperature was less than 35.0 degree C. Despite of warming with heating lamp and blankets, her core temperature did not reach 35.0 degree C during 18 hours. Ten days later, her temperature exceeded 36.0 degree C.
Adrenal Cortex Hormones/administration & dosage
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Adult
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Atrial Fibrillation/diagnosis
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Atrial Fibrillation/complications*
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Body Temperature/physiology
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Case Report
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Cyclophosphamide/administration & dosage
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Drug Therapy, Combination
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Electrocardiography
;
Female
;
Follow-Up Studies
;
Human
;
Hypothermia/therapy
;
Hypothermia/diagnosis
;
Hypothermia/complications*
;
Lupus Erythematosus, Systemic/drug therapy
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Lupus Erythematosus, Systemic/diagnosis
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Lupus Erythematosus, Systemic/complications*