1.A Case of Iron Deficiency Anemia with Hypoproteinemia.
Journal of the Korean Pediatric Society 1988;31(8):1054-1058
No abstract available.
Anemia, Iron-Deficiency*
;
Hypoproteinemia*
;
Iron*
2.Incidence of Lymphocytic Gastritis in Endoscopic Corporeal Varioliform Gastritis.
Hae Won HAN ; In Seok LEE ; Nak Gi KWAN ; Jae Myung PARK ; Jung Hwan OH ; Yu Kyung CHO ; Sang Woo KIM ; Myung Gyu CHOI ; In Sik CHUNG
Korean Journal of Gastrointestinal Endoscopy 2005;30(6):291-296
BACKGROUND/AIMS: Lymphocytic gastritis is characterised by the accumulation of small lymphocytes in the surface and foveolar epithelium. It is a common finding in a subtype of gastritis characterized by the presence of nodules and erosions in the body, relative to which the antrum was spared-'varioliform gastritis'. Lymphocytic gastritis usually follows a chronic course and presents severe clinical symptoms including hypoproteinemia. The aim of this study was to investigate the incidence and clinical manifestations of lymphocytic gastritis in patients who showed endoscopic apprearance of enlarged folds, erosions, and aphthoid nodules in the body. Materials and METHODS: The clinical and histological findings of varioliform gastritis with presence of nodules and erosions in the body were analyzed. The ratio of 25 lymphocytes/100 epithelial cell was used as the criteria for the diagnosis of lymphocytic gastritis in the study. RESULTS: Twenty nine cases were classified as varioliform gastritis (there were 20 men/9 women and average age was 48.9 years). Among the 29 varioliform gastritis, 9 corresponded to lymphocytic gastritis. H. pylori infection rate was 44% (4/9) in lymphocytic gastritis and 65% in non lymphocytic gastritis. There was no difference in H. pylori infection rate between the lymphocytic gastritis and non lymphocytic gastritis. Clinical laboratory findings of lymphocytic gastritis were normal. The patients with lymphocytic gastritis had absence of mild degree of symptoms. Among 4 patients with follow-up endoscopy, erosions in body were completely disappreared in 3 patients. CONCLUSIONS: Lymphocytic gastritis occurred in about 30% of patients with varioliform gastritis. Most patients with lymphocytic gastritis had no symptoms or only mild symptoms and had no significant abnormality in clinical or laboratory finding.
Diagnosis
;
Endoscopy
;
Epithelial Cells
;
Epithelium
;
Female
;
Follow-Up Studies
;
Gastritis*
;
Humans
;
Hypoproteinemia
;
Incidence*
;
Lymphocytes
3.Recurrent Systemic Capillary Leak Syndrome Responding to the Corticosteroid Therapy.
Eun Jung CHO ; In Hye CHA ; Ki Chul YOON ; Dae In LEE ; Tae Kyung LIM ; Young Sun KANG ; Dae Ryong CHA ; Young Sik KIM
Korean Journal of Nephrology 2010;29(4):513-518
Systemic capillary leak syndrome (SCLS) is a rare devastating condition that is caused by unexplained marked capillary hyperpermeability, resulting in hypovolemic shock, hemoconcentration, and hypoproteinemia. Most patients have prodromal symptoms such as non-specific gastrointestinal symptoms, myalgia, or dizziness. In the current case, we observed the patient with recurrent SCLS show perivascular lymphocytic infiltration on skin biopsy and eosinophilic infiltrates on random biopsies from duodenum to colon. This finding might be due to distinct eosinophilic enterocolitis or secondary to SCLS. However, there has been rare data for the prevention of the recurrent attack of SCLS, although the mortality is high. Therefore, we report a case of frequently relapsing SCLS responding to the corticosteroid therapy.
Biopsy
;
Capillaries
;
Capillary Leak Syndrome
;
Colon
;
Dizziness
;
Duodenum
;
Enterocolitis
;
Eosinophils
;
Humans
;
Hypoproteinemia
;
Prodromal Symptoms
;
Shock
;
Skin
4.A Case of Primary Intestinal Lymphangiectasia.
Geun Soo PARK ; Jin Young KWAK ; Joon Sik KIM ; Tae Chan KWON ; Yun Jeong JO
Korean Journal of Gastrointestinal Endoscopy 1999;19(4):634-642
We described a 22-month-old girl, who suffered from a gereralized edema and intermittent diarrhea for 1 month. Intestinal lymphangiectasia was confirmed by endoscopic biopsy. Endoscopic examination revealed showed the characteristic appearance of tiny white flakes scattered in the duodenum, which a histological examination confirmed to be dilated lymph vessels. The other findings from laboratory examinations included lymphopenia, hypoproteinemia, hypogammaglobulinemia and increased fecal a1-antitrypsin clearance. Treatment consisting of a low-fat diet and MCT supplementation was successful. The therapy has resulted in the disappearance of duodenal lesions previously observed endoscopically.
Agammaglobulinemia
;
Biopsy
;
Diarrhea
;
Diet, Fat-Restricted
;
Duodenum
;
Edema
;
Endoscopy
;
Female
;
Humans
;
Hypoproteinemia
;
Infant
;
Lymphopenia
6.Protein-losing gastropathy in a girl.
Jie LIU ; Hong MEI ; Bao-Xiang WANG ; Xue-Lian HE
Chinese Journal of Contemporary Pediatrics 2014;16(10):1057-1059
Child, Preschool
;
Edema
;
diagnosis
;
Female
;
Humans
;
Hypoproteinemia
;
diagnosis
;
Stomach Diseases
;
diagnosis
7.A Study of Vascular Reactivity Change in Nephrotic Syndrome Children Using Plethysmography.
Jae Won SHIM ; Byoung Hoon YOO ; In Suk LIM
Journal of the Korean Pediatric Society 1997;40(5):650-659
PURPOSE: The nephrotic syndrome is characterized by proteinuria, hypoproteinemia, edema and hyperlipidemia. These can change body homeostasis and cause hypertension. This study was designed to determine the relationship between the forearm vasodilating capacity and serum cholesterol level of nephrotic syndrome patients. METHODS: 15 Nephrotic syndrome patients and 17 normal control children who visited Chung-ang University Youngsan Hospital from Sep. 1995 to Sep 1996, were investigated. Each subject underwent forearm plethysmography for mearsurement of blood flow and vascular resistance. RESULTS: 1) Resting blood pressure, heart rate, forearm blood flow, vascular resistance was not significantly different in nephrotic syndrome group and control group. 2) After peak hyperemic periods, blood pressure, heart rate was not significantly different in nephrotic syndrome group and control group. 3) After hyperemic periods, peak forearm vascular blood flow was lower in nephrotic syndrom group (52.0+/-10.6mL/min/100ml) than control group (59.5+/-4.5mL/min/100mL), and minimal forearm vascular resistance was significantly higher in nephrotic syndrome group (1.8+/-0.5mmHg/mL/min/100mL) than control group (1.5+/-0.4mmHg/mL/min/100mL) (p<0.05). 4) vascular dilatation capacity (resting-hyperemic forearm vascular resistance difference) was also significantly lower in nephrotic syndrome group (6.3+/-1.6mmHg/mL/min/100) than control group. 5) Serum cholesterol level is significantly higher in nephrotic syndrome group (253.1+/-133.4mg/dL) than control group (183.5+/-41.0mg/dL). High cholesterol level related with nephrotic duration. 6) resting-hyperemic forearm vascular resistance difference is associated with relapsing frequence, but not associated with cholesterol level and nephrotic syndrome duration. CONCLUSIONS: These data suggest that reactive vascular changes in the forearm of nephrotic syndrome demonstrate early abnormalities of subclinical vascular changes, and these vascular change may contribute to cardiovacular disease and artherosclerosis.
Blood Pressure
;
Child*
;
Cholesterol
;
Dilatation
;
Edema
;
Forearm
;
Heart Rate
;
Homeostasis
;
Humans
;
Hyperlipidemias
;
Hypertension
;
Hypoproteinemia
;
Nephrotic Syndrome*
;
Plethysmography*
;
Proteinuria
;
Vascular Resistance
8.Co-Infection with Cytomegalovirus and Helicobacter pylori in a Child with Menetrier's Disease.
Yangho YOO ; Yoon LEE ; Yoo Min LEE ; Yon Ho CHOE
Pediatric Gastroenterology, Hepatology & Nutrition 2013;16(2):123-126
Menetrier's disease is a rare protein-losing gastropathy characterized by hypertrophic gastric fold, foveolar hyperplasia, and hypoproteinemia with resulting peripheral edema. It is clinically evident as nonspecific gastrointestinal symptoms, including abdominal discomfort, nausea and vomiting, abdominal pain, weight loss, diarrhea, and edema. Pediatric Menetrier's disease usually has an insidious onset and progressive, chronic clinical course and it spontaneously resolves in weeks or months. The pathogenesis of Menetrier's disease is not clearly understood. Menetrier's disease is thought to be associated with some gastric infections. But the cause of Menetrier's disease is unknown, an association with cytomegalovirus (CMV) and Helicobacter pylori has been suggested. In Korea, We present the first a case of pediatric Menetrier's disease with positive evidence of CMV and H. pylori.
Abdominal Pain
;
Child
;
Coinfection
;
Cytomegalovirus
;
Diarrhea
;
Edema
;
Gastritis, Hypertrophic
;
Helicobacter
;
Helicobacter pylori
;
Humans
;
Hyperplasia
;
Hypoproteinemia
;
Korea
;
Nausea
;
Vomiting
;
Weight Loss
9.The Investigation of Hypoproteinemia in Severe Infantile Atopic Dermatitis.
Ju Hee LEE ; Bong Ok SEO ; Eun Young LEE ; Sung Won KIM
Pediatric Allergy and Respiratory Disease 2008;18(4):316-325
PURPOSE: The aim of this study was to understand the clinical features and to analyze the risk factors for a severe complication such as hypoproteinemia in infants with severe atopic dermatitis. METHODS: Twenty-four infants with severe atopic dermatitis with SCORAD score >50 were enrolled, who visited pediatric allergy clinic between January 2005 and December 2007. Infants with blood protein level of <5 g/dL were classified Group A (n=8) and those of >5 g/dL as Group B (n=16). Age, sex, onset age, breast feeding, marternal protein-restriction diet during breast feeding, family history of allergy, and prior treatment before visit were studied. We examined serum ECP, total IgE, and allergen specific IgE by immuno CAP system (Phadia AB, Uppsala, Sweden) and tried to identify organisms by the culture of skin wound. Infants with blood protein level of <5 g/dL were classified Group A (n=8) and those of >5 g/dL as Group B (n=16). We also analyzed the risk factors for hypoproteinemia. RESULTS: Blood protein level was inversely correlated with total IgE (r=-0.610), SCORAD score (r=-0.686) and the number of sensitized allergens (r=-0.636). The sentisization of the house dust mite was also one of the risk factors for hypoproteinemia. CONCLUSION: Our study suggests that the risk factors for hypoproteinemia in infantile atopic dermatitis are high SCORAD score and the sentisization of the house dust mite and that hypoproteinemia associates with high serum levels of IgE and increased number of food sensitized allergens.
Age of Onset
;
Allergens
;
Breast Feeding
;
Dermatitis, Atopic
;
Diet
;
Humans
;
Hypersensitivity
;
Hypoproteinemia
;
Immunoglobulin E
;
Infant
;
Pyroglyphidae
;
Risk Factors
;
Skin
10.Report of a case with protein-losing gastroenteropathy.
Xin-lin HOU ; Ying WANG ; Yong-hong CHENG ; Wan-zhen LI
Chinese Journal of Pediatrics 2003;41(6):479-479