1.Severe Hypocalcemia Caused by Absorption of Sorbitol-Mannitol Solution during Hysteroscopy.
Guie Yong LEE ; Jong In HAN ; Hyun Joo HEO
Journal of Korean Medical Science 2009;24(3):532-534
Hysteroscopic procedure can be complicated by intravascular absorption of irrigating fluid. The clinical features of this complication are similar to transurethral resection of the prostate (TURP) syndrome. There have been few reports on hypocalcemia during endoscopoic surgery and clinical implications of hypocalcemia in TURP syndrome have been underestimated. We report a case of TURP syndrome association with a decreased ionized calcium concentration of 0.53 mM/L after the absorption of a large amount of sorbitol-mannitol solution during hysteroscopy. The hypotension which occurred in TURP syndrome did not respond to vasopressor and inotropic agent but responded to the administration of calcium. This case was also accompanied by hyponatremia, hyperglycemia and lactic acidosis through the metabolism of sorbitol.
Female
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Humans
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Hypocalcemia/*chemically induced/*diagnosis/therapy
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*Hysteroscopy
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Intraoperative Care
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Irrigation
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Mannitol/*adverse effects
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Middle Aged
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Pulmonary Edema/radiography
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Sorbitol/*adverse effects
2.Electrolyte Imbalances and Nephrocalcinosis in Acute Phosphate Poisoning on Chronic Type 1 Renal Tubular Acidosis due to Sjogren's Syndrome.
Sung Gun CHO ; Joo Hark YI ; Sang Woong HAN ; Ho Jung KIM
Journal of Korean Medical Science 2013;28(2):336-339
Although renal calcium crystal deposits (nephrocalcinosis) may occur in acute phosphate poisoning as well as type 1 renal tubular acidosis (RTA), hyperphosphatemic hypocalcemia is common in the former while normocalcemic hypokalemia is typical in the latter. Here, as a unique coexistence of these two seperated clinical entities, we report a 30-yr-old woman presenting with carpal spasm related to hypocalcemia (ionized calcium of 1.90 mM/L) due to acute phosphate poisoning after oral sodium phosphate bowel preparation, which resolved rapidly after calcium gluconate intravenously. Subsequently, type 1 RTA due to Sjogren's syndrome was unveiled by sustained hypokalemia (3.3 to 3.4 mEq/L), persistent alkaline urine pH (> 6.0) despite metabolic acidosis, and medullary nephrocalcinosis. Through this case report, the differential points of nephrocalcinosis and electrolyte imbalances between them are discussed, and focused more on diagnostic tests and managements of type 1 RTA.
Acidosis, Renal Tubular/*diagnosis/etiology
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Acute Disease
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Adult
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Antibodies, Antinuclear/blood
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Calcium Gluconate/therapeutic use
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Chronic Disease
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Female
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Humans
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Hydrogen-Ion Concentration
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Hypocalcemia/*chemically induced/complications/drug therapy
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Nephrocalcinosis/complications/*diagnosis/ultrasonography
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Parotid Gland/ultrasonography
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Phosphates/*adverse effects
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Salivary Glands/radionuclide imaging
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Sjogren's Syndrome/complications/*diagnosis/metabolism
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Submandibular Gland/ultrasonography