No abstract available.
Hypocalcemia*

No abstract available.
Humans ; Hypocalcemia* ; Infant*

No abstract available.
Basal Ganglia ; Hypocalcemia*

INTRODUCTION: Dengue is one of the causes of morbidity and mortality among pediatric patients. Calcium has been shown to play a role in the myocardial function of the patient and is a potential cause of mortality among dengue patients. This study aimed to determine the accuracy of hypocalcemia in predicting the severity of dengue among pediatric patients. METHODS: This is a systematic review and meta-analysis of published studies identified through an electronic literature search using PubMed/Medline, Cochrane Library, Herdin, Google Scholar, and hand search. Validity was assessed using the Cochrane risk of bias tool. Statistical analysis of the diagnostic test accuracy review was done using Review Manager 5.4.1 with the random effects model. Results showed sensitivity and specificity of hypocalcemia in severe dengue with a 95% confidence interval. The predictive values and likelihood ratios were also computed. RESULTS: Four studies were analyzed. The mean serum total and ionized calcium levels of patients were decreased among the severe dengue group. Data showed that there is a 74% sensitivity (95% CI = 0.58, 0.84) and 75% specificity (95% CI = 0.67, 0.81) with a positive predictive value of 67% and a negative predictive value of 90.7%. CONCLUSION This systematic review and meta-analysis showed that hypocalcemia may be a useful tool to predict severe dengue fever. However, further analysis is needed to strengthen the the diagnostic accuracy of hypocalcemia.
Severe Dengue ; Hypocalcemia

Objective: To determine the association of surgeon’s experience based on years of practice and incidence of post thyroidectomy hypocalcemia. Methods: Design: Retrospective cohort study. Setting: Tertiary Private Training Hospital. Participants: Records of patients who underwent total thyroidectomy in a private tertiary hospital from January 2003 to December 2018 were retrospectively reviewed. Medical information obtained were patient demographics, surgeon’s years of practice, thyroid specimen weight, technique of surgery, histopathologic findings and calcium assay values. Chi square test and Odds Ratio analysis were used to determine the relationship between the surgeon’s experience and post-thyroidectomy hypocalcemia. Results: Three hundred fourteen (314) patients who underwent total thyroidectomy from 2003 to 2018 were included in the study. Overall rate of post-operative hypocalcemia was 41%. On multivariate analysis, no significant odds ratio was found between surgeons with 5 to 19 years of experience and those with more than 19 years of experience in relation to post-operative hypocalcemia [Odds Ratio 1.4 (95% Confidence Interval 0.7 to 2.6)]. Odds ratios for other variables may be interpreted, however, they could not be generalized over the population where data was gathered since the 95% Confidence Interval includes 1. Conclusion The results of this retrospective cohort study suggest that post-thyroidectomy hypocalcemia is not associated with surgeon’s experience based on years of practice. Further studies are recommended in a multicenter approach to better generalize to the whole population.
Thyroidectomy ; Hypocalcemia ; Postoperative Complications

No abstract available.
Humans ; Hypocalcemia* ; Infant, Newborn ; Prognosis*

Pseudohypoparathyroidism(PHP) is an inherited metabolic disorder characterized by hypocalcemia, hyperphosphatemia and an impaired phosphaturic response to exogenous parathormone(PTH), which are caused by end organ resistance to the action of PTH. Most of these patients have, in addition, the skeletal abnormalities of Albright hereditary osteodystrophy. We report two cases of PHP, suspicious type Ia, in sibling who were presented with multiple subcutaneous soft tissue calcification similar to that seen in tumoral calcinosis and had short stature, round face, brachydactyly and metabolic abnormalities(hypocalcemia, hyperphosphatemia, increased serum PTH, and decreased 24hr urinary basal cAMP)
Brachydactyly ; Calcinosis ; Humans ; Hyperphosphatemia ; Hypocalcemia ; Pseudohypoparathyroidism* ; Siblings*

PURPOSE: Chronic use of anticonvulsant bring about abnormalities of bone metabolism, as hypocalcemia, rickets and osteomalacia. Early detection and treatment of abnormalities is important to pediatric patients. To investigate the usefulness of the serum Ca and 1,25(OH)2D3 as an predictor of bone metabolism abnormality, the study was done. METHODS: Serum Ca, P, ALP and 1,25(OH)2D3 were measured and analyzed in 48 children who diagnosed as convulsive disorder and took anticonvulsant medication over 6 months in Pediatric Department of Kyung Hee Medical Center. RESULTS: 1) Average duration of medication was 3.4+/-2.5yrs. 2) Values of serum Ca and P, ALP, 1,25(OH)2D3 were normal. 3) Serum levels of anticonvulsants were therapeutic range. 4) 1,25(OH)2D3 had significant correlation to serum Ca (P<0.005) and P (P<0.05) but no correlation to ALP. 5) Duration of medication had significant correlation to 1,25(OH)2D3 (P<0.05) but no correlation to Ca. 6) Duration of medication had no correlation to 1,25(OH)2D3 and Ca. CONCLUSIONS: Because 1,25(OH)2D3 is a good predictor for change of bone metabolism by chronic medication of anticonvulsant than Ca, its regular check is necessary.
Anticonvulsants ; Child ; Humans ; Hypocalcemia ; Metabolism* ; Osteomalacia ; Rickets

No abstract available.
Acidosis* ; Adrenal Insufficiency* ; Child* ; Diabetic Ketoacidosis* ; Emergencies* ; Humans ; Hypocalcemia* ; Hypoglycemia*

PURPOSE: Parathyroid injury is the major cause of post-thyroidectomy hypocalcemia. This prospective study aimed to define the relation between the preservation status of the parathyroid glands and post-thyroidectomy hypocalcemia as well as to determine whether the number of preserved parathyroid glands could be a guideline for the management of post-thyroidectomy hypocalcemia. METHODS: We analyzed a total of 76 cases of total thyroidectomy due to malignancy were analysed. Parathyroid gland status at the end of thyroidectomy was classified as preserved intact, discolored (color change or equivocal viability), or autotransplanted. Patients were grouped according to the number of intact preserved parathyroid glands into group 1 (more than two), group 2 (one), or group 3 (zero). The total and ionized serum calcium levels of each group were monitored for three days after surgery. RESULTS: The number of intact preserved parathyroid glands was not found to be closely related to serum calcium level, although ionized serum calcium level was significantly lower in group 1 than group 2 (P<0.001). Hypocalcemia was not found in group 1. Hypocalcemia was found in 31% (10/32) of group 2. Among the 32 patients of group 2, all 4 parathyroid gland were identified in 9 patients and 4 patients were shown to be hypocalcemic. Therefore, the incidence of hypocalcemia for patients in whom only one intact parathyroid was preserved and all 4 parathyroid were indentified was 44% (4/9). Hypocalcemia was transient in all patients. CONCLUSION: The parathyroid glands should be preserved as much as possible to minimize post-thyroidectomy hypocalcemia. The number of intact preserved parathyroid glands can be a good guideline for predicting post-thyroidectomy hypocalcemia and proper care management.
Calcium ; Humans ; Hypocalcemia* ; Incidence ; Parathyroid Glands ; Prospective Studies ; Thyroidectomy*