1.A clinical study for hyperprolactinemia.
Jeong Woo LEE ; Kyeong Bae PARK ; Kyu Jeong CHAE ; Mee Ok NA ; Chul Hee RHYEU ; Jong Duk KIM
Korean Journal of Obstetrics and Gynecology 1993;36(9):3477-3484
No abstract available.
Hyperprolactinemia*
2.Different Responses of Aripiprazole Combination Treatment in Antipsychotics-Induced Hyperprolactinemia: 2 Cases.
Jin Woo CHO ; Seung Min OH ; Chul Eung KIM
Korean Journal of Psychopharmacology 2015;26(2):58-60
Hyperprolactinemia is a well-known neuroendocrine side effect to antipsychotic agent. Combined treatment of aripiprazole is recognized as an effective solution against hyperprolactinemia caused by antipsychotic agent. We report 2 progressive clinical cases where both are treated with combined use of aripiprazole which has a unique mechanism of action to resolve olanzapine and amisulpride-induced hyperprolactinemia.
Hyperprolactinemia*
3.Factors Influencing Disconnection Hyperprolactinemia and Reversal of Serum Prolactin after Pituitary Surgery in a Non-Functioning Pituitary Macroadenoma
Thinesh Kumran ; Saffari Haspani ; Jafri Malin Abdullah ; Azmi Alias ; Fan Rui Ven
Malaysian Journal of Medical Sciences 2016;23(1):72-76
Background: To investigate factors influencing disconnection hyperprolactinemia, including tumour volume, degree of pituitary stalk displacement and extent of tumour growth based on a modified Wilson-Hardy classification in a non-functioning pituitary macroadenoma and to confirm reductions in serum prolactin levels after endoscopic transphenoidal surgery. Methods: This prospective, descriptive study was conducted in the Department of Neurosurgery, General Hospital Kuala Lumpur from Jan 1, 2011 to Jan 1, 2013. Forty patients fulfilling the inclusion criteria were enrolled. All patients underwent endoscopic transphenoidal resection of non-functioning pituitary macroadenoma. Pituitary stalk angle, tumour volume and extent of tumour growth were measured from Magnetic Resonance Imaging (MRI) pre- and post-operatively. These variables were compared to serum prolactin levels measured pre and post operatively. SPSS 21 was used to perform statistical analyses. Results: In 40 patients, the mean tumour volumes were 10.58 cm3 (SD 7.81) pre-operatively and 3.1 cm3 (SD 3.45) post-operatively. There was a 70% reduction in tumour volume post-operatively (P < 0.01). The mean serum prolactin was 457 mIU/L (SD 66.93) pre-operatively and 297 mIU/L (SD 6.73) post-operatively. There was a 65% reduction in prolactin serum levels after surgery (P < 0.01). The mean pituitary stalk angles were 93.45 ± 3.89 degrees pre-operatively and 51.45 ± 1.46 degrees post-operatively (P = 0.01). The mean pituitary stalk angle in the control group was 50.4 ± 8.80 degrees. Hence, there was a 98% reduction in pituitary stalk angle after surgery (P < 0.01). This study showed a linear correlation between the pre-operative and post-operative tumour volumes and serum prolactin levels (P = 0.01 pre-and post-operative) and between serum prolactin levels and pituitary stalk angle (P = 0.20 pre-operative; P = 0.01 post-operative). Conclusion: Tumour volume and pituitary stalk angle displacement have positive predictive values for disconnection hyperprolactinemia in non-functioning pituitary macroadenoma. However, a larger sample size and further objective studies are needed to confirm these findings.
Hyperprolactinemia
4.Clinical approach of Hyperprolactinemia.
Korean Journal of Medicine 2007;72(6):698-701
No abstract available.
Hyperprolactinemia*
;
Prolactinoma
5.Hyperprolactinemia secondary to hypothyroidism accompanied by depression.
Journal of Korean Neuropsychiatric Association 1991;30(5):920-926
No abstract available.
Depression*
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Hyperprolactinemia*
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Hypothyroidism*
6.Dopamine agonists in the treatment of hyperprolactinemia cycle and fertility disorders: comparison between lisuride and bromocriptine.
Journal of Korean Society of Endocrinology 1992;7(1):8-15
No abstract available.
Bromocriptine*
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Dopamine Agonists*
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Dopamine*
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Fertility*
;
Hyperprolactinemia*
;
Lisuride*
7.A Case of Impotence due to Pituitary Adenoma.
Jin Sun CHO ; Doo Sung LEE ; Hyung Ki CHOI
Korean Journal of Urology 1986;27(6):977-979
The endocrine cause of impotence is about 10-15% of all impotence. If hyperprolactinemia is noted, the pituitary adenoma should be suspected. Usually, the early symptom of pituitary adenoma is impotence and other symptoms of CNS appear later. So impotence is a very important clinical symptom not to be neglected. It had taken 8 years to diagnose the pituitary adenoma, whose early symptom was impotence. He received operation and radiotherapy and has been taking care of his sustaining hyperprolactinemia. When we review his past history. it is not overemphasized that impotence is important to diagnose pituitary adenoma."
Erectile Dysfunction*
;
Hyperprolactinemia
;
Male
;
Pituitary Neoplasms*
;
Radiotherapy
8.Hyperprolactinemia After Severe Head Trauma.
Jae Suk PARK ; Jae Gon MOON ; Chang Hyun KIM ; Hong Dae KIM ; Ho Kook LEE ; Soo Young JUNG ; Do Yun HWANG
Journal of Korean Neurosurgical Society 2002;31(1):65-66
Patients of head injury may manifest neurohypophyseal dysfunction during the early post-traumatic period. A case of hyperprolactinemia and low prolactin response to thyrotrophin-releasing hormone in a woman 7 months after severe head injury is presented and literatures are also reviewed.
Craniocerebral Trauma*
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Female
;
Head*
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Humans
;
Hyperprolactinemia*
;
Prolactin
9.Postictal Serum Prolactin Values and Its Significance in Convulsive Disorder.
Wan Yong SHIN ; Sa Jun CHUNG ; Chang Il AHN
Journal of the Korean Pediatric Society 1994;37(11):1573-1578
The authors analysed 196 cases of convulsive disorder in children who were admitted to the pediatric department of Kyunghee Hospital from June 1993. Blood samples were drawn immediately following seizures on arrival. Serum prolactin values were measured by radioimmunoassay. The results obtained were as follows: 1) Mean serum prolactin value was 55.4+/-20.8ng/ml in generalized seizures within 1 hr following seizures, 22.5+/-3.9ng/ml in partial seizures. There was a significant difference between generalized scizures and partial scizures (p<0.05). 2) Mean serum prolactin value was 23.5+/-9.7ng/ml in generalized seizures within 1~3 hrs following seizures, 10.4+/-4.9ng/ml in partial seizures. There was a significant difference between generalized seizures and partial seizures (p<0.05). 3) Mean serum prolactin value was 9.5+/-4.4ng/ml in generalized seizures 3 hrs following seizures, 9.8+/-4.8ng/ml in partial seizures. There was no significant difference between generalized seizures and partial seizures (p>0.05). We found transient hyperprolactinemia following generalized seizures but a little change following gartial seizures. Postictal elevation of serum prolactin may represent a biochemical marker of generalized and partial seizures.
Biomarkers
;
Child
;
Humans
;
Hyperprolactinemia
;
Prolactin*
;
Radioimmunoassay
;
Seizures
10.The Efficacy of Radiation Therapy in the Treatment of Pituitary Adenoma.
Heung Lee CHO ; Kwang Mo YANG ; Seung Chang SHON ; Hyun Suk SUH
Journal of the Korean Society for Therapeutic Radiology 1990;8(2):163-168
Between 1984 and 1989, 22 patients with pituitary adenomas were treated with radiation therapy. The tumor was controlled in 18 of 22 (81.8%) patients for an observed period of II to 98 months. Eleven of 12 (92%) patients with visual field defect experienced nomalization or improvement, and 3 of 5 evaluable patients with hyperprolactinemia achieved normalization in one and decrement in two patients. We concluded that: (a) postoperative radiotherapy is clearly effective in the controlling of clinical symptoms and signs resulting from pituitary adenoma: (b) In the macroadenoma, the difference of control rate between suprasellar, <2cm. And suprasellar,>2cm. Was not significant.
Humans
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Hyperprolactinemia
;
Pituitary Neoplasms*
;
Radiotherapy
;
Visual Fields