Benign prostate hyperplasia (BPH) and chronic prostatitis (CP) are common diseases in males, and BPH is often complicated by CP. This review focuses on the relationship of BPH with CP and their epidemiology, pathogenesis and clinical features. Patients with BPH or CP are more likely to be subjected to another disease. Inflammation may be involved in the development of BPH. Compared with simple BPH, patients with CP-complicated BPH have significantly higher scores on age, prostate weight, prostate volume, and IPSS. Some related therapies are also evaluated, such as selective use of the alpha1-receptor blocker, 5alpha-reductase inhibitor, antibiotics, ultrasound microbubble contrast agents, and so on.
Chronic Disease ; Humans ; Male ; Prostatic Hyperplasia ; complications ; Prostatitis ; complications

With the development of living standard and the aging society, the incidences of metabolic syndrome and benign prostatic hyperplasia are getting higher and higher. Recent studies show that both metabolic syndrome and benign prostatic hyperplasia are associated with blood vessel injury, hyperinsulinemia and over-activity of the sympathetic nerve. This article presents an overview on the interaction of these two diseases.
Humans ; Hyperinsulinism ; Male ; Metabolic Syndrome ; complications ; Prostatic Hyperplasia ; complications

Benign prostatic hyperplasia(BPH) and prostatitis are two common diseases in aging men. In recent years, the study of correlation between these two diseases has been paid more and more attention to. Some researchers presumed that inflammation is one of the most important causations of BPH, however, it is not profound enough on this etiologic hypothesis at present. The writer, on the base of his clinical experiences, dissertated the etiology of BPH, the pathologic figures of coexistence of BPH and prostatitis, and the presumption of inflammation promoting BPH on the molecular biology level. We hope our colleagues pay attention to this problem, and do more study on it.
Humans ; Male ; Prostatic Hyperplasia ; complications ; etiology ; Prostatitis ; complications ; etiology

Diabetes Complications ; Diabetes Mellitus ; Humans ; Hypertension ; complications ; Male ; Prostatic Hyperplasia ; complications

Prostatic diseases and erectile dysfunction (ED) are common diseases in urology and andrology. Basic and clinical studies have proved that there is a close relationship between the two. This article reviews the mechanism, diagnosis and treatment of ED caused by several prostatic diseases, such as acute prostatitis, chronic prostatitis, benign prostate hyperplasia and prostate cancer.
Chronic Disease ; Erectile Dysfunction ; diagnosis ; etiology ; therapy ; Humans ; Male ; Prostatic Diseases ; complications ; Prostatic Hyperplasia ; complications ; Prostatic Neoplasms ; complications ; Prostatitis ; complications

OBJECTIVETo explore the clinical characteristics of benign prostatic hyperplasia (BPH) complicated by chronic prostatitis (CP).

METHODSA total of 120 cases of BPH pathologically confirmed after transurethral resection of the prostate (TURP) were assigned to a BPH group (n=75) and a BPH + CP group (n=45) according to whether they were complicated by CP. The total prostatic volume (TPV) and PSA density (PSAD) were calculated and statistically analyzed based on the results of transrectal ultrasonography and f-PSA, t-PSA and f-PSA/t-PSA tests before surgery.

RESULTSThe BPH group showed a significantly upward tendency in f-PSA and t-PSA (P < 0.05) with the increase of age or prostate volume, but not significantly in PSAD and f-PSA/t-PSA (P > 0.05). In comparison, the BPH + CP group exhibited remarkable increases in f-PSA, t-PSA and PSAD (P < 0.05) but not in fPSA/t-PSA (P > 0.05). ROC curve analyses of various indexes showed the area under the curve to be 0.644, 0.628 and 0.624 for f-PSA, t-PSA and PSAD, respectively, all between 0.5 and 0.7.

CONCLUSIONBPH is frequently associated with CP. Clinically, high f-PSA, t-PSA and PSAD are important but not sure indicators of BPH complicated by CP.

Aged ; Chronic Disease ; Humans ; Male ; Prostatic Hyperplasia ; complications ; diagnosis ; Prostatitis ; complications ; diagnosis

OBJECTIVETo investigate the early diagnosis and treatment of congenital adrenal hyperplasia (CAH) complicated by testicular adrenal rest tumors (TART).

METHODSWe retrospectively analyzed the clinical data of 1 case of late-onset CAH complicated by TART diagnosed and treated in Xiamen Women and Children Health Care Hospital.

RESULTSThe patient was a 15 years old boy, short statured and dark skinned, with skin pigmentation in the gum and external genital, secondary sex characteristics of the adult and irregular tubercles palpable in the bilateral testes. Laboratory examinations showed obviously increased levels of ACTH, 17-KS, DHEA-S and progesterone and evidently decreased levels of FSH, LH and CO. The low-dose dexamethasone suppression test reduced ACTH and DHEA-S to normal. Imaging examinations revealed soft tissue density in the bilateral adrenal glands, especially on the right, and irregularly increased volume of the bilateral testes, particularly on the left, with heterogeneous signals and septas and surrounded by the fluid signals. Histopathological examinations showed the eosinophilic cytoplasm to be polygon- or round-shaped, interstitium-like cells arranged in line, and lipopigment in the endochylema. Immunohistochemical results were negative for testicular interstitial cell tumor. The clinical signs of the patient were improved after 3 months of dexamethasone treatment, the hyperplastic nodules in the left testis decreased obviously and those in the right testis disappeared after 6 months, and the hyperplastic nodules in the adrenal glands vanished after 9 months.

CONCLUSIONBased on the clinical manifestations and the results of auxiliary examinations, this case was diagnosed as late-onset CAH complicated by TART, which was attributed to the continued surge of ACTH induced by corticoadrenal insufficiency. Sufficient dexamethasone treatment could make the TART decrease or disappear and the CAH vanish; it could also improve the clinical symptoms and bring the laboratory results to normal.

Adolescent ; Adrenal Hyperplasia, Congenital ; complications ; Adrenal Rest Tumor ; complications ; Humans ; Male ; Retrospective Studies

Humans ; Male ; Prostatic Hyperplasia ; complications ; Quality of Life ; Urinary Bladder, Overactive ; complications

We present here the radiological findings of a rare case of multiple focal nodular hyperplasia that was associated with portal vein atresia and portopulmonary hypertension in a young woman. This case illustrates and supports the pathophysiological hypotheses that were previously proposed for the coexistence of these three abnormalities.
Adult ; Female ; Focal Nodular Hyperplasia/*radiography ; Humans ; Hypertension, Portal/*complications ; Hypertension, Pulmonary/*complications ; Portal Vein/*abnormalities

The patient is a 75 years old man complaining of ear plug and hearing loss for about three days. Physical examination shows liquid in two tympanic cavities. Chronic congestion occurs to nasal mucosa. Bilateral inferior turbinates are a little bigger than normal. Both inferior meatus are unblocked and pharyngeal recess is smooth. This patient is fat. Bilateral eye lids are swollen. A tumour could be touched in bilateral parotids with good movement and no tenderness. Its size is as big as an egg. Several lymph nodes could be touched under the jaw. The blood test is normal and IgG, IgA, IgM, ANA, anti-ENA, C3, C4, CRP and ESR is normal but RF is high. The function of liver and kidney is normal. B-mode ultrasonography result shows bilateral parotids are diffusely swollen and several swollen lymph nodes in cervix. Pathology examination of lower mandibular lymph node and parotid shows follicular lymphaticus hyperplasia with several plasmacytes and eosinophil granulocytes. The diagnosis accords with Kimura disease.
Aged ; Angiolymphoid Hyperplasia with Eosinophilia ; complications ; Humans ; Male ; Otitis Media with Effusion ; complications