We describe two cases of right hyperglycemia hemichorea (HGHC) with identical Tc-99m TRODAT-1/ Tc-99m ECD scan findings. While the brain MRI showed signal alterations within the left putamen, there was evidence of hyperperfusion on Tc-99m TRODAT-1 but hypoperfusion on Tc-99m ECD within the left putamen, in association with hyperperfusion within left thalamus on Tc-99m ECD. The discrepancy between the Tc-99m TRODAT-1 and Tc-99m ECD scan provides insight into the imbalance between direct and indirect circuits along the nigrostriatal pathway, as the fundamental genesis of HGHC. Furthermore, the hyperperfusion at the left thalamus represents thalamic disinhibition secondary to loss of pallidal negative control, which ultimately leads to HGHC through re-entrant outflow to the motor cortex.
Hyperglycemia

No abstract available.
Hyperglycemia

No abstract available.
Adipocytes ; Hyperglycemia

No abstract available.
Adipocytes ; Hyperglycemia

Introduction: Adiponectin is an adipocytokine known to have anti-inflammatory and anti-atherogenic effects. It appears to impact insulin resistance and the subsequent development of type 2 diabetes mellitus (T2D). The gene encoding adiponectin ADIPOQ, has single nucleotide polymorphisms (SNPs) that can be useful biomarkers to predict development of T2D; with the T/G polymorphism of SNP +45 in exon 2 being the most common. Objective: This study was conducted to evaluate the association of T45G adiponectin gene polymorphism with hyperglycemia among adult Filipinos seen at the outpatient department of the Philippine General Hospital. Methods: This is a matched case-control study, with duration of 12 months. DNA was extracted using the QIAGEN MIDI Blood Extraction Kit. The genomic DNA obtained was then subjected to real time PCR for SNP detection. Results: One hundred (100) adults were enrolled; forty-three (43) had normoglycemia, while fifty seven (57) had hyperglycemia, after a 75-g oral glucose tolerance test. Hyperglycemic subjects were older (44±15.6 years vs. 52±8.3 years, p-value 0.002), and had lower HDL levels (58.5±16.0 mg/dLvs. 47.8+11.8 mg/dL, p-value 0.000). Among thirty-nine (39) participants found to have the T45G adiponectin gene polymorphism, 22 or 56.4% were hyperglycemic while 17 or 43.6% were normoglycemic. Conclusion There was no significant association observed between the T45G SNP and presence of hyperglycemia.
Adiponectin ; Hyperglycemia

No abstract available.
Humans ; Hyperglycemia* ; Peritoneal Dialysis*

A prospective, cross sectional study on 70 acute cerebral infarction patients from 40 to 84 years of age was carried out at The Stroke Centre of Central Military Hospital 108 between July 2004 and June 2005. the patients were diagnosed by clinical examination and cerebral X-ray computed tomography. Results as followed: among these patients, sudden onset occurred in 94.3%, mainly in the morning (55.7%). Risks factors: hypertension 78.6%, dyslipidemia 85.7%, diabetes 18.6%, ischemic 21.4%. Clinical symptoms: hemiplegia 97.1%, cerebral nerve damage 81.4%, language disorder 47.1%... Hyperglycemia at acute stage of stroke were common with 54.3%. Serve paralyze were more common in hyperglycemia group. This suggested that persisitent hyperglycemia at acute stage of stroke associated with worse clinical outcome and rehabilitation after stroke
Hyperglycemia ; Stroke ; Rehabilitation

No abstract available.
Glucose* ; Humans* ; Hyperglycemia* ; Monocytes*

Seizures are a common presenting manifestation in patients in a nonketotic hyperglycemic(NKH) hyperosmolar state and the MR findings are typically hyperintense on T2 weighted (T2-W) and fluid attenuated inversion recovery (FLAIR) images. We recently experienced a case of the patient with partial seizure and nonketotic hyperglycemia who showed T2-W and FLAIR hypointensities with T1 weighted (T1-W) contrast enhancement.
Humans ; Hyperglycemia ; Seizures

No abstract available.
Humans ; Hyperglycemia ; Hyperkalemia