Idiopathic hypereosinophilic syndrome is characterized by multiorgan involvement without any cause, and peripheral eosinophilia(1,500/microliter) for more than 6 months. Clinically, many organs can be involved, but the heart is the most commonly involved organ. Although lung involvement is usual(20-30%)1) in hypereosinophilic syndrome, there are few reports of eosinophilic pneumonia proven by biopsy confirmation in Korea. We experienced a case of hypereosinophilic syndrome with eosinophilic pneumonia and bronchitis confirmed by biopsy, and we report it here with a review of the literature.
Biopsy ; Bronchitis* ; Eosinophils* ; Heart ; Hypereosinophilic Syndrome* ; Korea ; Lung ; Pulmonary Eosinophilia*

We report a case of idiopathic hypereosinophilic syndrome (HES) presenting with deep vein thrombosis and subsequent massive pulmonary embolism. The eosinophilia and thromboembolism improved dramatically with systemic corticosteroid and anticoagulation therapy. However, the early and rapid tapering of corticosteroid, in a state of normal eosinophil count and therapeutic PT level, aggravated thromboembolism. An immediate retrial of corticosteroid made disease improve again. The etiology of HES and the pathogenesis of thrombus formation in HES still remain uncertain but corticosteroid in treatment of HES is yet cardinal and should be maintained for a prolonged period of time.
Eosinophilia ; Eosinophils ; Hypereosinophilic Syndrome* ; Pulmonary Embolism* ; Thromboembolism ; Thrombosis ; Venous Thrombosis*

No abstract available.
Hypereosinophilic Syndrome*

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Hypereosinophilic Syndrome*

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Hypereosinophilic Syndrome*

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Hypereosinophilic Syndrome*

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Hypereosinophilic Syndrome*

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Hypereosinophilic Syndrome*

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Hypereosinophilic Syndrome

Transient peripheral eosinophilia occurs in several disorders, such as allergic diseases, cancer, and parasitic in fections. However, in most cases, their persence is not accompanied by tissue destruction or organ dysfunc tion. In certain disease states, eosinophils can accumulate in any organ in the body and cause tissue destruction as a result of the eosinophil infiltration or the toxic effects of the degranulated proinflammatory products. Idiopathic hypereosinopilic syndrome is a rare disorder characterized by persistent eosinophilia of an unknown origin, usually associated with a dysfunction of organs such as the heart, lung, skin, and nervous system. Idiopathic hypereosinophilic syndrome usually has an indolent course over a period of several months. However, in some cases, they have grave symptoms if vital organs such as heart and lung are infiltrated. Here we report a case of idiopathic hypereosinophilic syndrome presenting acute pulmonary edema involving the heart, bone marrow, and lung with a review of the relevant literatures.
Bone Marrow ; Eosinophilia ; Eosinophils ; Heart ; Hypereosinophilic Syndrome* ; Lung ; Nervous System ; Pulmonary Edema* ; Skin