1.Lipid-lowering effect of omega-3 fatty acid in patients with hypercholesterolemia.
Seung Nam LEE ; Hoon Ki PARK ; Yong Eun KIM ; In Hong HWANG ; Bong Yul HUH
Journal of the Korean Academy of Family Medicine 1991;12(1):1-7
No abstract available.
Humans
;
Hypercholesterolemia*
2.Lipoprotein X Detected in a Case of Hypercholesterolemia Associated With Chronic Cholangiohepatitis.
Jihye HA ; Sang Guk LEE ; Jeong Ho KIM
Annals of Laboratory Medicine 2017;37(6):550-552
No abstract available.
Hypercholesterolemia*
;
Lipoprotein-X*
;
Lipoproteins*
3.Effects of lovastatin on serum lipids of patients with primary hypercholesterolemia.
Kyung Soo KIM ; Jung Hyun KIM ; Hun Kil LIM ; Bang Hun LEE ; Jung Kyoon LEE
The Korean Journal of Critical Care Medicine 1993;8(1):7-11
No abstract available.
Humans
;
Hypercholesterolemia*
;
Lovastatin*
4.Multiple xanthoma tuberosum in a case of familial homozygous hypercholesterolemia
Pankaj Singhania ; Pritam Biswas ; Abhranil Dhar
Journal of the ASEAN Federation of Endocrine Societies 2023;38(1):134-135
A 15-year-old, Indian, female child of a second-degree consanguineous marriage, presented with polymorphic yellowish-brown nodular cutaneous lesions over the dorsal aspect of both elbows, knees (Figure 1A) and buttocks (Figure 1B). These were suggestive of xanthoma tuberosum and were first noted at 4 years old. There were no spots over the eyelids, acanthosis, skin tags or tendon xanthomas. Arcus juvenilis was not noted. A bilateral carotid bruit was appreciated.
xanthoma
;
familial
;
hypercholesterolemia
;
LDL
5.Clinical Efficacy of Pravastatin in Patients with Hypercholesterolemia.
June Soo KIM ; Ki Hoon HAN ; Seung Woo PARK ; Joon Kyung BANG ; Suk Keun HONG ; Dae Won SOHN ; Byung Hee OH ; Myoung Mook LEE ; Young Bae PARK ; Yun Shik CHOI ; Jung Don SEO ; Young Woo LEE
Korean Circulation Journal 1992;22(1):113-120
BACKGROUND: This study was designed to evaluate the clinical efficacy of pravastatin, HMG-CoA reductase inhibitor, in patients with hypercholesterolemia. Methods and RESULTS: Pravastatin 5 mg was administered twice daily for 12 weeks in twenty five patients(12 male, 13 female) with hypercholesterolemia(>240 mg/dl). Compared with pretreatment levels, pravastatin significantly decreased levels of total cholesterol(281+/-41mg/dl versus 218+/-31mg/dl) by 22% and LDL-cholesterol(199+/-46mg/dl versus 137+/-37mg/dl) by 31% with significantly decreased total-cholesterol/HDL-cholesterol ratio(7.1+/-3.0 versus 5.1+/-1.6) and LDL-cholesterol/HDL-cholesterol ratio(5.1+/-2.5 versus 3.3+/-1.4) (p<0.005, respectively). During pravastatin treatment, the level of Apo B(164+/-38mg/dl versus 123+/-20mg/dl) was decreased significantly by 24% with significantly decreased Apo B/Apo A-1 ratio(1.4+/-0.5 versus 1.0+/-0.3) (p<0.005, respectively). No serious side effects were found. CONCLUSIONS: Results from the present study show that pravastatin is an effective and well-tolerated cholesterol-lowering agent.
Humans
;
Hypercholesterolemia*
;
Male
;
Oxidoreductases
;
Pravastatin*
7.Clinical Efficacy of Lovastatin in Patients with Hypercholesterolemia.
June Soo KIM ; In Ho CHAI ; Seung Woo PARK ; Suk Keun HONG ; Hyo Soo KIM ; Cheol Ho KIM ; Dae Won SOHN ; Byung Hee OH ; Myoung Mook LEE ; Young Bae PARK ; Yun Shik CHOI ; Jung Don SEO ; Young Woo LEE
Korean Circulation Journal 1992;22(1):121-129
BACKGROUND: This study was designed to evaluate the clinical efficasy of lovastatin, HMG-CoA reductase inhibitor, in patients with hypercholesterolemia. METHODS AND RESULTS: Lovastatin 20 to 80 mg were administered once daily for 12 weeks in twenty five patients(11 male, 14 famale ; nine patients with familial hypercholesterolemia) with hypercholesterolemia(>240mg/dl). Compared with pretreatment levels, lovastatin significantly decreased levels of total cholesterol(309+/-46mg/dl versus 201+/-37mg/dl) by 35%, LDL-cholesterol(230+/-48mg/dl versus 125+/-40mg/dl) by 46% and triglyceride(170+/-76 versus 142+/-66mg/dl) by 11% (p<0.05) with significantly decreased levels of total-cholesterol/HDL-cholesterol ratio(7.4+/-2.1 versue 4.6+/-1.5) and LDL-cholesterol/HDL-cholesterol ratio(5.6+/-1.9 versue 2.9+/-1.4) (p<0.005 except triglyceride, respectively). The level of Apo B(183+/-32mg/dl versus 114+/-26mg/dl) was decreased significantly by 37%(p<0.005) with significantly decreased level of Apo A-1(115+/-22 to 122+/-26mg/dl) was increased significantly by 6%(p<0.05). No serious side effects were found. CONCLUSIONS: Results from the present study show that lovastatin is an effective and well-tolerated cholesterol-lowering agent.
Humans
;
Hypercholesterolemia*
;
Lovastatin*
;
Male
;
Oxidoreductases
;
Triglycerides
8.Serum lipid level and risk factor analysis of hypercholesterolemia during continuous ambulatory peritoneal dialysis.
Heung Soo KIM ; Ki Yong KIM ; Chan Sin PARK ; Han Sun CHO ; Kyu Hun CHOI ; Sung Kyu HA ; Ho Young LEE ; Dae Suk HAN ; Moon Jae KIM
Korean Journal of Nephrology 1992;11(4):417-426
No abstract available.
Hypercholesterolemia*
;
Peritoneal Dialysis, Continuous Ambulatory*
;
Risk Factors*
9.Clinical Effect of Procetofene(Lipanthyl(R)) on the Serum Lipids in the Hyperlipidemic Patients.
Yun Shik CHOI ; Jeong Sik PARK ; Jeongdon SEO ; Young Woo LEE
Korean Circulation Journal 1981;11(1):113-119
We observed the levels of serum cholesterol, triglyceride and HDL-cholesterol in 28-hyperlipidemic patients after treatment with procetofene(Lipanthyl(R)), a new hypolipidemic agent. The results were as follows. 1. The hyperlipidemic patients were 7 cases of pure hypercholesterolemia, 12 cases of mixed hyperlipidemia and 9 cases of pure hypertriglyceridemia. 2. All the patients were treated with daily dose of 200 to 400mg, usually 300mg, and duration of more than 12 weeks. 3. The serum cholesterol decreased significantly at the rate of 29% in pure hypercholes terolemia and 29% in mixed hyperlipidemia after treatment for 12 weeks. 4. The serum triglyceride decreased significantly at the rate of 58% in mixed hyperlipidemia and 42% in pure hypertriglyceridemia after treatment for 12 weeks. 5. The serum HDL-cholesterol increased at the rate of 10% in pure hypercholesterolemia, 14% in mixed hyperlipidemia and 26% in pure hypertriglyceridemia after treatment for 12 weeks, but the increase rate was statistically significant only in pure hypertriglyceridemia. 6. Transient epigastric discomfort was complained by 2 patients, but subsided spontaneously with continuous treatment. 7. In view of these results, procetofene appears to be an effective and well tolerated agent for the treatment of all the types of hyperlipidemia.
Cholesterol
;
Fenofibrate
;
Humans
;
Hypercholesterolemia
;
Hyperlipidemias
;
Hypertriglyceridemia
;
Triglycerides
10.Treatment of Hypercholesterolemia in Elderly Patients; From the Viewpoint of Statins.
Seong Choon CHOE ; Sora LEE ; Chul Joon KIM
Journal of the Korean Geriatrics Society 2002;6(4):253-260
No abstract available.
Aged*
;
Humans
;
Hydroxymethylglutaryl-CoA Reductase Inhibitors*
;
Hypercholesterolemia*