No abstract available.
Hyperamylasemia*

No abstract available.
Hyperamylasemia* ; Sertraline*

Acute pancreatitis as a complication of organophosphate intoxication has been infrequently addressed. Previous reports have suggested that acute pancreatitis may follow the oral ingestion of several organophosphates. The pathogenesis of this pancreatic damage has been studied in a few animal studies. However, the association between acute pancreatits and human organophosphate intoxication may still not be widely recognized. We experienced 6 cases described as hyperamylasemia and hyperlipasemia with a presumptive diagnosis of acute pancreatitis following organophosphate intoxication, and we analyzed them to provide human baseline data for further studies and patient management. We report these case series with an analysis and a literature review.
Animals ; Diagnosis ; Eating ; Humans ; Hyperamylasemia ; Organophosphates ; Pancreatitis*

There is growing evidence that oxygen-derived free radicals(OFR's) play a role in the pathogenesis of pancreatic diseases, especially of acute pancreatitis. Many types of experimental ex vivo and in vitro pancreatitis can be inhibited by superoxide dismutase and catalse. (continue...)
Hyperamylasemia* ; Oxygen* ; Pancreatic Diseases ; Pancreatitis ; Superoxide Dismutase

Humans ; Hyperamylasemia ; physiopathology ; Infant, Newborn ; Neonatology

For many years ERCP has been contraindicated in acute pancreatitis. The injection of contrast medium. which may cause hyperamylasemia and occasionally an attack of acute pancreatitis even in normal indivisuals, was allowed only two to three weeks after subsidence of symptoms. Gallstone disease is one of the most common etilogical factors in pancreatitis and migration or impaction of gallstone in the ampulla of Vater causes pancreatitis. (continue...)
Ampulla of Vater ; Cholangiopancreatography, Endoscopic Retrograde* ; Gallstones ; Hyperamylasemia ; Pancreatitis*

BACKGROUND/AIMS: To describe a simple and useful modification of the rendezvous technique using a PTBD tube as guidance. METHODS: From January 2005 to August 2006, a total of 436 ERCPs were performed. A diagnosis of choledocholithiasis was made in 235 cases. Deep cannulation of the bile duct using standard techniques was unsuccessful in 27 patients (11.5%). A precut papillotomy led to successful cannulation in 16 out of these 27 patients (59.3%). The remaining 11 patients (40.7%) underwent PTBD with the tube tip placed in the second portion of the duodenum. Bile duct cannulation was attempted with the guidance of a PTBD tube in 9 cases. In the other 2 cases, the transduodenal approach was impossible due to a previous Billroth II operation. RESULTS: Bile duct cannulation guided by a PTBD tube, which is also known as a modified rendezvous procedure, was successful in 9 out of 11 patients (81.8%). Deep cannulation of the bile duct was achieved in 100% of patients, who could be treated by endoscopy. There were 7 cases of transient hyperamylasemia (77.8%) but no procedure-related major complications or mortality. CONCLUSIONS: Bile duct cannulation guided by a PTBD tube in patients with choledocholithiasis can be recommended when ERCP is unsuccessful using the standard technique.
Bile Ducts* ; Bile* ; Catheterization* ; Cholangiopancreatography, Endoscopic Retrograde ; Choledocholithiasis ; Diagnosis ; Drainage* ; Duodenum ; Endoscopy ; Gastroenterostomy ; Humans ; Hyperamylasemia ; Mortality

PURPOSE: The aim of this study is to examine whether conventional primary closure of the bile duct without routinely inserting a T-tube could be performed after all the surgeries used to treat choldocholithiasis. METHODS: From April 2002 to July 2005, we retrospectively analyzed 125 bile duct stone disease patients who underwent primary closure of the bile duct. RESULTS: Wound infection was the most frequent surgical complications, and it showed a higher trend in the patients who had a history of previous biliary operation, and it showed a trend to be slightly higher in the recurrent biliary stone cases than that in the de novo cases. However, these findings were not statistically significant. In addition, surgical complications developed in 16 of 100 patients who were older that 60 years, whereas there was only 1 of 25 patients who developed complications for the patients younger than 60 years. The development of complications has a tendency to be higher for the older patients, yet the level was not statistically significant. In regard to postsurgical hyperamylasemia, although a statistically significant difference could not be detected, this malady developed in 3 of 12 cases in whom endoscopic nasobiliary drainage (ENBD) tubes were inserted. This showed a trend to be higher than that for 13 cases of 113 patients for whom endoscopic nasobiliary drainage tubes were not inserted. Concerning the postsurgical hospitalization period, it was significantly longer in the cases who developed complications (p=0.018), and there was a tendency for a prolonged hospitalization period for the patients who were older than 60 years, for women, recurrent cases and the cases with a history of the bile duct surgery. Yet these had no statistical significance CONCLUSION: It appears that the primary closure of bile duct is a technique that could be performed safely for all choledocolithotomy patients , and this is regardless of the size of bile duct diameter, history of surgery on the bile duct system, gender, emergency operation, age, recurrent biliary stones, the presence of presurgical nasobiliary drainage tube and the presence of concomitant diseases.
Bile Ducts* ; Bile* ; Choledocholithiasis ; Drainage ; Emergencies ; Female ; Hospitalization ; Humans ; Hyperamylasemia ; Length of Stay ; Retrospective Studies ; Wound Infection

We have reported that serum amylase and lipase level elevate immediately after total gastrectomy independent to whether the pancreas is manipulated or not. Although we found high levels of amylase and lipase from the draining fluid via intraabdominal drain, none of them became pancreatic fistula. To check the amylase and lipase level after distal gastrectomy and to check whether the protease inhibitor (gabexate mesilate) reduce the elevated amylase and lipase, we made a prospective study. A Jackson-Pratt drain was inserted intraperitoneally during the operation to check amylase and lipase levels postoperatively. We present the postoperative changing patterns of amylase and lipase levels in the draining fluid. Serum amylase and lipase levels were also monitored. We found elevation of amylase and lipase concentrations in the draining fluid for a few days after distal gastrectomy. However, none of the patients developed pancreatic fistula, although all of the surgical methods showed hyperamylasemia and hyperlipasemia. Postoperative treatment with protease inhibitor was not effective against the elevated amylase and lipase levels in serum or draining fluid.
Amylases ; Gabexate ; Gastrectomy* ; Humans ; Hyperamylasemia ; Lipase ; Pancreas ; Pancreatic Fistula ; Prospective Studies ; Protease Inhibitors*

The trans-sphenoidal resection of a recurred pituitary tumor was performed in a 42 years old man under general anesthesia with propofol and remifentanil. Neither massive bleeding nor hypotension was observed intraoperatively, but bradycardia was sustained over five hours. The patient did not suffer from hypertriglyceridemia and there was no evidence of drug toxicity or vigorous intervention during the surgery, however hyperamylasemia was observed one day after the surgery. It is presumed that vagal stimulation by propofol and remifentanil infusion might induce bradycardia and abnormal pancreatic enzyme secretion consequently.
Anesthesia, General ; Bradycardia ; Drug Toxicity ; Hemorrhage ; Humans ; Hyperamylasemia ; Hypertriglyceridemia ; Hypotension ; Piperidines ; Pituitary Neoplasms ; Propofol