1.Plasma immunoreactive endothlin-1, creatine kinase and CK isoenzyme and its relation to neonate with asphyxia.
Kang Woo LEE ; Kee Hyoung LEE ; Chang Sung SON ; Young Chang TOCKGO
Journal of the Korean Pediatric Society 1993;36(10):1434-1440
Endotheline-1 (ET-1) is a potent vasoconstrictor peptide with 21 amino acid residues. ET-1 is thought to have a key role in vasoconstriction, and cardiac, renal, and endocrine actions of the peptide. Creatine Kinase(CK), also referred to as ATP-creatine-N-phosphotransferase, consists of either the B or M type. CK is found almost exclusively in muscle(MM), myocardium(MB), and brain(BB). It is to be an almost specific index of injury of myocardium and brain in hypoxic damage. I measured the ET-1, CK isoenzyme in neonates among asphyxia group (14 cases), as a control devide into two group. 1st group(birth weight (2500 g, n=9) and 2nd group (body weight 2500g, n=11). 1) There was no significant difference between asphyxia and control 1st, 2nd group during postnatal 24 hrs include cord blood on irET-1(p< 0.05). 2) There was significant difference between asphyxia and control 1 st, 2nd group during postnatal 24 hrs include cord blood on CK and CK and CK isoenzyme (p<0.001). 3) There was significant difference between asphyxia and control 1st, 2nd group on CK-MB and CK-BB proportion (p< 0.001). 4) There was significant difference between cord blood and postnatal 24 hrs on total CK level (P< 0.001).
Asphyxia*
;
Brain
;
Creatine Kinase*
;
Creatine*
;
Fetal Blood
;
Humans
;
Infant, Newborn*
;
Myocardium
;
Plasma*
;
Vasoconstriction
2.A Case of Chronic Pancreatitis with Pancreatic Stones in Childhood.
Young Kyoo SHIN ; Chan Wook WOO ; Kee Hyoung LEE ; Young Chang TOCKGO ; Chang Duck KIM
Journal of the Korean Pediatric Society 1995;38(7):1012-1017
No abstract available.
Pancreatitis, Chronic*
3.Scintigraphic findings of nineteen cases of ectopic thyroid.
In Ho CHO ; Hyun Dae YOON ; Kyu Chang WON ; Chan Woo LEE ; Hyoung Woo LEE ; Hyun Woo LEE
Korean Journal of Nuclear Medicine 1993;27(2):183-190
No abstract available.
Thyroid Dysgenesis*
4.Estimation of Glomerular Filtration Rate(GFR) Using (99m)Tc-DTPA Renal Scan and the Parameters for Renal Function.
Ihn Ho CHO ; Hyun Dae YOON ; Kyu Chang WON ; Chan Woo LEE ; Hyoung Woo LEE ; Hyun Woo LEE
Yeungnam University Journal of Medicine 1994;11(1):101-108
Many previously described nuclear medicine procedures to assess glomerular filtration rate have some problems because numerous blood sample is to be taken and they don't measure each separate renal function. Gates described isotopic method for the measurement of global and unilateral GFR based on the fractional renal uptake of (99m)Tc-DTPA 2 to 3 minutes after its intravenous injection. We evaluated GFR using (99m)Tc-DTPA in 57 people according to Gates method and compared with creatinine clearance. A good correlation was observed between creatinine clearance and GRF calculated by Gates' formula with an r value of 0.9(P<0.05). And also the relationship between parameters of (99m)Tc-DTPA renal scan images and GFR was taken. They were significantly correlated with GFR calculated by Gates' formula : r value 0.66 between relative intensity of peak renal to peak aortic activity(pK/pA) and GFR, -0.42 between time between aortic and kidney peak(A-K) and GFR and -0.48 between parenchymal renal activity at 25 min compared to peak kidney activity(25K/pK) and GRF. In conclusion, the determination of GFR according to Gates' formula shows good and reproducible of GRF with rapidity and simplicity. And the parameters from the renal scan images can use to estimate the renal function.
Creatinine
;
Filtration*
;
Glomerular Filtration Rate
;
Injections, Intravenous
;
Kidney
;
Methods
;
Nuclear Medicine
5.A case of combined pregnancy in term pregnant woman.
Chang Hee LEE ; Tae Seung CHO ; Young Woo SHIN ; Soo Hyoung SEO ; Dong Han BAE
Korean Journal of Obstetrics and Gynecology 1993;36(3):420-424
No abstract available.
Female
;
Humans
;
Pregnancy*
;
Pregnant Women*
6.Extracorporeal Membrane Oxygenation for 67 Days as a Bridge to Heart Transplantation in a Postcardiotomy Patient with Failing Heart and Mediastinitis.
Hyoung Woo CHANG ; Yang Hyun CHO ; Suhyun CHO ; Kiick SUNG ; Pyo Won PARK
Korean Journal of Critical Care Medicine 2015;30(4):295-298
We report a case of successful heart transplantation after 67 days of support with venoarterial extracorporeal membrane oxygenation (ECMO) in a patient who underwent surgery for type A aortic dissection and myocardial infarction complicated by irreversible myocardial damage and a deep sternal wound infection. During ECMO support, left heart vent and distal limb perfusion were performed. Mediastinitis was treated with mediastinal washout and irrigation. Multiple complications from peripheral ECMO were successfully managed.
Cardiomyopathies
;
Extracorporeal Membrane Oxygenation*
;
Extremities
;
Heart Transplantation*
;
Heart*
;
Humans
;
Mediastinitis*
;
Myocardial Infarction
;
Perfusion
;
Shock
;
Transplantation
;
Wound Infection
7.Total Hip Replacement Using High Hip Center in Osteoarthritis Secondary to Hip Dysplasia(Preliminary study)
Byung Woo MIN ; Chang Soo KANG ; Kwang Soon SONG ; Chearl Hyoung KANG ; Gi Won PARK
The Journal of the Korean Orthopaedic Association 1995;30(6):1610-1617
Total hip replacement for adults with severe acetabular dysplasia presents a difficult problem because deficient bone stock and soft tissue contractures usually prevent sitting at the normal anatomic level. The rationales of high hip center are due to high failure rate of bulk structural weight bearing graft, good short-term result of hemispherical cementless acetabular component in revision surgery, high hip center but not lateral which does not adversely affect the biomechanics of the hip, and intimate apposition with viable host bone. We represented the short-term results of 21 total hip replacements with proximal placement of the acetabular cup than the anatomical position that is normally used. The mean duration of follow up was 18 months(range, 12-58 months) and the mean age of the patient was fifty-one years(range, thirty to sixty-seven years). Most of these hips had a major deficiency or defect of the acetabular bone stock. They had an aver- age Harris hip score of 47 points preoperatively and 90 points postoperatively. Roentgenographic measurements showed that the mean change in the height of the center of the hip postoperatively was only +6.6 millimeters and the mean change of horizontal location of them was 10 millimeters medial to the preoperative position. Postoperative complications included calcar fracture(1 case), trochanteric bursitis(1 case), postop- erative dislocation(1 case) and one case of radiological loosening of the acetabular component. The center of the hip in THR is not a crucial parameter with regard to the long-term stability of acetabular component, so our recommendation is to place the acetabular component at a more proximal but not lateral position if strong bone stock is available. But future studies of high hip center need to address femoral component longevity.
Acetabulum
;
Adult
;
Arthroplasty, Replacement, Hip
;
Contracture
;
Femur
;
Follow-Up Studies
;
Hip Joint
;
Hip
;
Humans
;
Longevity
;
Osteoarthritis
;
Postoperative Complications
;
Transplants
;
Weight-Bearing
8.Correlation between 5-minute 99mTc-pertechnetate uptake and 24-hour131I uptake in patients with thyroid disease.
Chan Woo LEE ; Kyu Chang WON ; Hyun Dae YOON ; In Ho CHO ; Tae Nyeun KIM ; Dong Gu SHIN ; Hyoung Woo LEE ; Bong Sup SHIM ; Hyun Woo LEE
Korean Journal of Nuclear Medicine 1992;26(2):280-289
No abstract available.
Humans
;
Thyroid Diseases*
;
Thyroid Gland*
9.A case of SIADH in small cell lung cancer.
Kyu Chang WON ; Jong Sik LIM ; Chan Woo LEE ; Hyoung Woo LEE ; Choong Ki LEE ; Jin Hong CHUNG ; Myoung Soo HYUN ; Bong Sup SHIM ; Hyun Woo LEE
Yeungnam University Journal of Medicine 1991;8(2):227-234
The syndrome of inappropriate ADH secretion is a disorder characterized by hyponatremia which results from water retention attributable to ADH release. The hallmark of SIADH is hyponatremia due to water retention, in the presence of urinary osmolality above plasma osmolality. The SIADH was initially described by Schwartz et al (1957). This syndrome, first recognized in patients with bronchogenic carcinoma, has now been observed in a variety of other illnesses. Recently, we encountered a 59 year-old female with small cell lung cancer, also she had SIADH. Thus, we present a case and review the literature on the subject.
Carcinoma, Bronchogenic
;
Female
;
Humans
;
Hyponatremia
;
Inappropriate ADH Syndrome*
;
Osmolar Concentration
;
Plasma
;
Small Cell Lung Carcinoma*
;
Water
10.Subthalamic Deep Brain Stimulation for Parkinson's Disease.
Chul Hyoung LYOO ; Jin Woo CHANG ; Myung Sik LEE
Journal of the Korean Neurological Association 2006;24(3):191-203
The recent progress in the basic knowledge of basal ganglia pathways and advances in the techniques of the neuroimaging studies enabled subthalamic deep brain stimulation (STN DBS). In Korea, more than three hundreds and fifty patients with PD have been treated with STN DBS since the first trial at March 2000. STN DBS effectively improves all parkinsonian deficits occurring especially during levodopa 'off' period and decreases the daily 'off' time. The daily requirement of levodopa dosage can be reduced to about half of the preoperative one. The favorable responses to the STN DBS can be maintained even after five years. However, parkinsonian deficits during levodopa 'on' period can not be controlled as effectively as those during the levodopa 'off' period. The axial symptoms including gait disturbance and postural instability during the levodopa 'on' period cannot be improved or even are worsen by STN DBS. Patients aged over 70 frequently show less remarkable improvement of parkinsonian deficits than the younger ones. Therefore, selection of appropriate candidate for STN DBS is the most important factor deciding the outcome of the STN DBS.
Basal Ganglia
;
Deep Brain Stimulation*
;
Gait
;
Humans
;
Korea
;
Levodopa
;
Neuroimaging
;
Parkinson Disease*
;
Subthalamic Nucleus