We report herein a case of eosinophilic pustular follicultis in a 20-year-old man. The patient showed typical clinical picture with specific laboratory and histopathological findings of eosinophilic pustular folliculitis. The patient responded well to systemic administration of corticosteroid and dapsone.
Dapsone ; Eosinophils* ; Folliculitis* ; Humans ; Young Adult

l6-year-old male and 48-year-old female with systemic lupus erythematosus (SLE) and renal disease presented with vesiculobullous eruptions during severe attack of the disease. They showed hypocomplementernia, and high ANA titers. Histopathologic findings revealed subepidermal blister and leukocytoclastic vasculitis, Direct immunofluorescence demonstratedlinear deposits of IgG, IgA and lgM at the dermoepidermal junction. The vesiculobullous eruption of SLE may be an important marker reflecting disease activity and prognosis.
Blister ; Female ; Fluorescent Antibody Technique, Direct ; Humans ; Immunoglobulin A ; Immunoglobulin G ; Lupus Erythematosus, Systemic* ; Male ; Middle Aged ; Prognosis ; Vasculitis

A case of scabies combined with superficial dermatophytosis which was aggravated by application of topical fluorinated steroid for 6 months is presented. One year ago a 60-year-old male began to have pruritic erythematous papules on the lower abdomen which spread slowly to the inguinal and buttock area. He had had onychomycosis for six years and for the last 6 months he had applied a. fluorinated steroid. preparation. After application of steroid, the aggravated skin lesions spread rapidly over the whole body. A KOH mount showed sarcoptes scabiei and fungus. A count of itch mites from scales brushed off and collected from. the overall surface of the patients body showed 263 adults, 169 Iarvae and 534 eggs. T. rubrum from a culture of scales from the trunk and nails was confirmed. On admission FBS and oral GTT test revealed diabetic curve, however it could not be determined whether the diabetes mellitus was primary or secondary to the use of topical steroid application. The patient has been treated with crotamiton cream and antifungal agent with remarkably effective results.
Abdomen ; Adult ; Buttocks ; Diabetes Mellitus ; Eggs ; Fungi ; Humans ; Male ; Middle Aged ; Mites ; Onychomycosis ; Ovum ; Sarcoptes scabiei ; Scabies* ; Skin ; Tinea* ; Weights and Measures

The importance of the ticks in medical field has been emphasized because of their association with and transmission of various diseases. We report herein a case of tick bite in a 55-year-old male farmer, who visited our hospital on July 2, 1981 with a parasite attached on right lower flank and rice to small pea sized, pruritic erythematous papular skin eruptions on chest and right lower flank. The skin lesions disappeared completely with.in five days after removal of the parasite, which was identified with an adult female tick which belongs to Genus Ixodes.
Adult ; Female ; Humans ; Ixodes* ; Male ; Middle Aged ; Parasites ; Peas ; Skin ; Thorax ; Tick Bites* ; Ticks*

Schwannomas rarely present as intraocular tumors and are often misdiagnosed as malignant melanoma. We describe a choroidal schwannoma confirmed by sclerouvectomy. A 30-year-old woman presented with a large nonpigmented intraocular mass of the choroid in the right eye and underwent surgical excision by sclerouvectomy. Histologically, the tumor was composed of a mixture of cellular solid components (Antoni A) and loose myxoid components (Antoni B). The tumor was eventually diagnosed as a schwannoma. Currently available ancillary studies are still of little value in definitively differentiating schwannomas from other choroidal tumors. In the case of atypical findings for a malignant melanoma, a benign neoplasm should be included in the differential diagnosis. This patient avoided enucleation by first having the mass excised. We are unaware of previous reports in which a choroidal schwannoma was diagnosed by surgical excision.
Adult ; Choroid/*pathology ; Choroid Neoplasms/*diagnosis/surgery ; Diagnosis, Differential ; Eye Enucleation/*methods ; Female ; Humans ; Magnetic Resonance Imaging ; Neurilemmoma/*diagnosis/surgery

PURPOSE: To investigate the epidemiologic and clinical features of uveal melanomas in Korean patients. METHODS: The medical records of 35 patients (35 eyes) with the diagnosis of uveal melanoma between September 2004 and December 2006 were reviewed retrospectively. RESULTS: Of the 35 patients, 22 were males (62.9%) and 13 were females (37.1%), with a mean age at diagnosis of 48.2+/-14.1 years (range, 24-82 years). Decreased visual acuity was the most common symptom in 23 patients (65.7%), while 6 patients (17.1%) were detected without prior symptoms. The shape of the uveal melanoma was dome-shaped in 27 eyes (77.1%) and mushroom-shaped in 8 eyes (22.9%). The mean largest basal diameter of the tumors was 9.0+/-3.3 mm (2.4-19.0 mm), and the mean apical height was 6.2+/-2.6 mm (1.1-13.0 mm). The tumors were classified according to their size; a small melanoma was found in 4 eyes (11.4%), a medium melanoma in 29 eyes (82.9%), and a large melanoma in 2 eyes (5.7%). CONCLUSIONS: Uveal melanomas manifest earlier in Korean patients than in Caucasian patients. At the time of diagnosis, 33 eyes (94.3%) had small or medium melanomas that could be treated.
Eye ; Female ; Humans ; Male ; Medical Records ; Melanoma ; Retrospective Studies ; Uveal Neoplasms ; Visual Acuity

Purpose: To investigate the clinical and pathological classification of eyelid and conjunctival tumors in Korean patients. Methods: We retrospectively reviewed the medical records of 284 patients with eyelid skin tumors and 158 with conjunctival tumors between January 2011 and June 2020. Demographic, clinical, and histopathological data were analyzed. Results: In total, 260 (91.5%) and 24 (8.5%) patients had benign and premalignant/malignant eyelid tumors, respectively. The mean age was 54.7 ± 20.1 and 72.0 ± 13.5 years, respectively and the most common benign and malignant tumors were intradermal nevus (21.5%) and basal cell carcinoma (4.2%), respectively. The second most common malignant tumor was sebaceous gland carcinoma (1.4%). The conjunctival tumors included 133 (84.2%) benign tumors and 25 (15.8%) premalignant/malignant tumors, in patients with an average age of 47.9 ± 22.2 and 60.7 ± 18.3 years, respectively. The most common benign and malignant conjunctival tumors were subepithelial nevus (13.3%) and lymphoma (10.1%), respectively. The patients with premalignant/ malignant eyelid tumors were significantly older than those with premalignant/malignant conjunctival tumors (p = 0.01). Conclusions The incidence of sebaceous gland carcinoma was higher in our study than in Western ones, which showed similar results to other East Asian studies. The most common conjunctival malignant tumor was lymphoma in our study and malignant melanoma in Western studies. It is necessary to consider the possibility of lymphoma when the tumor is in the palpebral conjunctiva, where mucosal lymphoid tissue is abundant. This study provides useful data on the incidence and characteristics of eyelid and conjunctival tumors in Korean patients. Further investigations in larger patient populations are required to better understand the epidemiology of eyelid and conjunctival tumors.

Purpose: To investigate the clinical and pathological classification of eyelid and conjunctival tumors in Korean patients. Methods: We retrospectively reviewed the medical records of 284 patients with eyelid skin tumors and 158 with conjunctival tumors between January 2011 and June 2020. Demographic, clinical, and histopathological data were analyzed. Results: In total, 260 (91.5%) and 24 (8.5%) patients had benign and premalignant/malignant eyelid tumors, respectively. The mean age was 54.7 ± 20.1 and 72.0 ± 13.5 years, respectively and the most common benign and malignant tumors were intradermal nevus (21.5%) and basal cell carcinoma (4.2%), respectively. The second most common malignant tumor was sebaceous gland carcinoma (1.4%). The conjunctival tumors included 133 (84.2%) benign tumors and 25 (15.8%) premalignant/malignant tumors, in patients with an average age of 47.9 ± 22.2 and 60.7 ± 18.3 years, respectively. The most common benign and malignant conjunctival tumors were subepithelial nevus (13.3%) and lymphoma (10.1%), respectively. The patients with premalignant/ malignant eyelid tumors were significantly older than those with premalignant/malignant conjunctival tumors (p = 0.01). Conclusions The incidence of sebaceous gland carcinoma was higher in our study than in Western ones, which showed similar results to other East Asian studies. The most common conjunctival malignant tumor was lymphoma in our study and malignant melanoma in Western studies. It is necessary to consider the possibility of lymphoma when the tumor is in the palpebral conjunctiva, where mucosal lymphoid tissue is abundant. This study provides useful data on the incidence and characteristics of eyelid and conjunctival tumors in Korean patients. Further investigations in larger patient populations are required to better understand the epidemiology of eyelid and conjunctival tumors.

Purpose: The coronavirus disease 2019 (COVID-19) outbreak has significantly impacted the diagnosis and treatment of breast cancer. Our study investigated the change in diagnosis and treatment of breast cancer with the progress of COVID-19 pandemic. Materials and Methods: The study group comprised 6,514 recently diagnosed breast cancer patients between January 1, 2019, and February 28, 2021. The patients were divided into two groups: pre–COVID-19 period (3,182; January 2019 to December 2019) and COVID-19 pandemic period (3,332; January 2020 to February 2021). Clinicopathological information related to the first treatment after breast cancer diagnosis was retrospectively collected and analyzed in the two groups. Results: Among the 6,514 breast cancer patients, 3,182 were in the pre–COVID-19 period and 3,332 were in the COVID-19 pandemic period. According to our evaluation, the least breast cancer diagnosis (21.8%) was seen in the first quarter of 2020. The diagnosis increased gradually except for the fourth quarter in 2020. While early-stage breast cancer was diagnosed 1,601 (48.1%) during the COVID-19 pandemic (p=0.001), the number of surgical treatments increased 4.6% (p < 0.001), and the treatment time was slightly shorter 2 days (p=0.001). The breast cancer subtype distribution was not statistically different between the pre–COVID-19 and COVID-19 period groups. Conclusion In the early stages of the pandemic, the number of breast cancer cases temporarily decreased; however, they stabilized soon, and no significant differences could be identified in the diagnosis and treatment when compared to the period before the pandemic.

A 70-year-old male came to the emergency room of the authors' hospital because of sudden cardiac arrest due to inferior wall ST elevation myocardial infarction. His coronary angiography revealed multiple severe coronary spasms in his very long left anterior descending artery. After an injection of intracoronary nitroglycerine, his stenosis improved. The cardiac arrest relapsed, however, accompanied by ST elevation of the inferior leads, while the patient was on diltiazem and nitrate medication to prevent coronary spasm. Recovery was not achieved even with cardiac massage, intravenous injection of epinephrine and atropine, and intravenous infusion of nitroglycerine. The patient eventually recovered through high-dose nicorandil intravenous infusion without ST elevation of his inferior leads. Therefore, intravenous infusion of a high dose of nicorandil must be considered a treatment option for cardiac arrest caused by refractory coronary vasospasm.
Arteries ; Atropine ; Cardiopulmonary Resuscitation ; Constriction, Pathologic ; Coronary Angiography ; Coronary Vasospasm ; Death, Sudden, Cardiac ; Diltiazem ; Emergencies ; Epinephrine ; Heart Arrest ; Heart Massage ; Hemodynamics ; Humans ; Infusions, Intravenous ; Injections, Intravenous ; Male ; Myocardial Infarction ; Nicorandil ; Nitroglycerin ; Porphyrins ; Spasm