No abstract available.
Female ; Gonadotropin-Releasing Hormone* ; Gonadotropins* ; Granulosa Cells* ; Progesterone*

No Abstract Available.
Estrogens*

OBJECTIVE: To investigate the basal bone mineral density(BMD)s of the lumbar spine and femur of patients with endometriosis, and the changes of BMDs and biochemical bone markers after 6 months of gonadotropin releasing hormone(GnRH) agonist treatment. METHODS: The initial BMDs of 35 women with endometriosis were measured by dual energy x-ray absorptiometry at department of obstetrics & gynecology Yongsan Hospital, College of Medicine, Chung Ang University from April 1996 to May 1999. 19 patients of these group was repeatedly measured after 3.6mg subcutaneous depot injection of goserelin(Zoladex) every 4 weeks for 24 weeks. Osteocalcin and Deoxypyridinoline were measured before goserelin treatment, at 3 months, and at 6 months completion of goserelin treatment. RESULTS: Patients with endometriosis did not show the significant difference in mean BMD of lumbar spine and femur in comparison with age matched normal women. Patients treated with goserelin for 6 months showed 0.064+/-0.030g/cm2(5.56%) decrease of BMD in lumbar spine, 0.038+/-0.040g/cm2(3.85%) decrease in femur neck, 0.055+/-0.047g/cm2(6.10%) decrease in Ward triangle, 0.041+/-0.031g/cm2(5.19%) decrease in femoral trochanter. These data had statistical significance(p<0.001). At first 3 months and on completion of 6 months goserelin treatment, there were increase of 66.1%, 122.3% in serum osteocalcin respectively, and increase of 35.2%, 39.6% in urine deoxypyridinoline respectively, compared with pretreatment value. CONCLUSION: From these results, it is concluded that the BMDs of patients with endometriosis were normal, and after 6 months GnRH agonist treatment, bone loss was 3.85%-6.10%, and the values of biochemical bone markers were increased.
Absorptiometry, Photon ; Bone Density* ; Endometriosis* ; Female ; Femur ; Femur Neck ; Gonadotropin-Releasing Hormone* ; Gonadotropins ; Goserelin ; Gynecology ; Humans ; Obstetrics ; Osteocalcin ; Spine

No abstract available.
Humans ; Infant, Newborn* ; Lipoproteins* ; Plasma*

No abstract available.
Pregnancy*

OBJECTIVE: In Korea, only a few reports were introduced about body fat mass of women with using the Dual energy X-ray absorptiometry (DEXA), highly sensitive and specific measurement for fat mass analysis. This study was carried out to determine whether total and regional body composition changes measured by DEXA were more related to age or to menopause. METHODS: One hundred fifteen postmenopausal women who had never received estrogen replacement therapy were enrolled in Menopausal Clinic from January 2001 to April 2002. BMD and body composition were measured by DEXA. The proportions of android and gynoid fat were calculated in all women and differences were sought by ANOVA test, Pearson correlation and multiple linear regression. RESULTS: They were classified as perimenopausal women (n=31), young postmenopausal women (n=60) or old postmenopausal women (n=24). Bone mineral content (BMC), BMD, leg lean body mass and gynoid fat were significant differences among three groups. In multiple linear regression, age was a predictor of total, trunk and leg BMC (p<0.01), total, L2-4 and proximal femur BMD (p<0.01), total, arm and trunk fat percentage of total body mass and trunk regional fat percentage of regional tissue (p<0.05), whereas years since of age was not a predictor of any of the body composition variables. CONCLUSION: The findings of this study suggest that BMC, BMD and body fat distribution with a shift toward a more central location in postmenopausal women. This change appears to be more related to age than to menopause.
Absorptiometry, Photon ; Adipose Tissue ; Arm ; Body Composition* ; Body Fat Distribution ; Bone Density ; Estrogen Replacement Therapy ; Female ; Femur ; Humans ; Korea ; Leg ; Linear Models ; Menopause*

No abstract available.
Estrogen Replacement Therapy* ; Estrogens* ; Female ; Gonadotropins* ; Humans ; Ovariectomy*

No abstract available.
Aging* ; Female* ; Humans ; Korea*

No abstract available.
Aging* ; Female* ; Humans ; Korea*

No abstract available.
Myasthenia Gravis* ; Pregnancy*