1.Direct modulatory action of gonadotropin releasing hormone agonist on ovarian function : Effect on progesterone production in FSH-stumilated procine granulosa cell culture.
Korean Journal of Obstetrics and Gynecology 1993;36(9):3466-3476
No abstract available.
Female
;
Gonadotropin-Releasing Hormone*
;
Gonadotropins*
;
Granulosa Cells*
;
Progesterone*
2.Selective Estrogen Receptor Modulators(SERMs).
Journal of Korean Society of Endocrinology 2000;15(2):139-149
No Abstract Available.
Estrogens*
3.The changes of bone mineral density and biochemical bone markers after GnRH agonist treatment in patients with endometriosis.
Hyoung Moo PARK ; Min HUR ; Yoon Sook KIM
Korean Journal of Obstetrics and Gynecology 2000;43(1):87-94
OBJECTIVE: To investigate the basal bone mineral density(BMD)s of the lumbar spine and femur of patients with endometriosis, and the changes of BMDs and biochemical bone markers after 6 months of gonadotropin releasing hormone(GnRH) agonist treatment. METHODS: The initial BMDs of 35 women with endometriosis were measured by dual energy x-ray absorptiometry at department of obstetrics & gynecology Yongsan Hospital, College of Medicine, Chung Ang University from April 1996 to May 1999. 19 patients of these group was repeatedly measured after 3.6mg subcutaneous depot injection of goserelin(Zoladex) every 4 weeks for 24 weeks. Osteocalcin and Deoxypyridinoline were measured before goserelin treatment, at 3 months, and at 6 months completion of goserelin treatment. RESULTS: Patients with endometriosis did not show the significant difference in mean BMD of lumbar spine and femur in comparison with age matched normal women. Patients treated with goserelin for 6 months showed 0.064+/-0.030g/cm2(5.56%) decrease of BMD in lumbar spine, 0.038+/-0.040g/cm2(3.85%) decrease in femur neck, 0.055+/-0.047g/cm2(6.10%) decrease in Ward triangle, 0.041+/-0.031g/cm2(5.19%) decrease in femoral trochanter. These data had statistical significance(p<0.001). At first 3 months and on completion of 6 months goserelin treatment, there were increase of 66.1%, 122.3% in serum osteocalcin respectively, and increase of 35.2%, 39.6% in urine deoxypyridinoline respectively, compared with pretreatment value. CONCLUSION: From these results, it is concluded that the BMDs of patients with endometriosis were normal, and after 6 months GnRH agonist treatment, bone loss was 3.85%-6.10%, and the values of biochemical bone markers were increased.
Absorptiometry, Photon
;
Bone Density*
;
Endometriosis*
;
Female
;
Femur
;
Femur Neck
;
Gonadotropin-Releasing Hormone*
;
Gonadotropins
;
Goserelin
;
Gynecology
;
Humans
;
Obstetrics
;
Osteocalcin
;
Spine
4.Cord plasma lipid and lipoprotein levels of newborn infants.
Chang Joo KIM ; Hyoung Moo PARK ; Do Hwan BAE
Korean Journal of Perinatology 1993;4(3):285-294
No abstract available.
Humans
;
Infant, Newborn*
;
Lipoproteins*
;
Plasma*
5.Pregnancy associated with kyphoscoliosis, a review of 3 cases.
Joung Hwan KIM ; Hyoung Moo PARK ; Do Hwan BAE
Korean Journal of Obstetrics and Gynecology 1992;35(8):1238-1241
No abstract available.
Pregnancy*
6.Relative influence of age and menopause on total and regional Body composition changes measured by DEXA in Postmenopausal Women.
Soo Hyun CHO ; Hyoung Moo PARK
Korean Journal of Obstetrics and Gynecology 2005;48(5):1294-1305
OBJECTIVE: In Korea, only a few reports were introduced about body fat mass of women with using the Dual energy X-ray absorptiometry (DEXA), highly sensitive and specific measurement for fat mass analysis. This study was carried out to determine whether total and regional body composition changes measured by DEXA were more related to age or to menopause. METHODS: One hundred fifteen postmenopausal women who had never received estrogen replacement therapy were enrolled in Menopausal Clinic from January 2001 to April 2002. BMD and body composition were measured by DEXA. The proportions of android and gynoid fat were calculated in all women and differences were sought by ANOVA test, Pearson correlation and multiple linear regression. RESULTS: They were classified as perimenopausal women (n=31), young postmenopausal women (n=60) or old postmenopausal women (n=24). Bone mineral content (BMC), BMD, leg lean body mass and gynoid fat were significant differences among three groups. In multiple linear regression, age was a predictor of total, trunk and leg BMC (p<0.01), total, L2-4 and proximal femur BMD (p<0.01), total, arm and trunk fat percentage of total body mass and trunk regional fat percentage of regional tissue (p<0.05), whereas years since of age was not a predictor of any of the body composition variables. CONCLUSION: The findings of this study suggest that BMC, BMD and body fat distribution with a shift toward a more central location in postmenopausal women. This change appears to be more related to age than to menopause.
Absorptiometry, Photon
;
Adipose Tissue
;
Arm
;
Body Composition*
;
Body Fat Distribution
;
Bone Density
;
Estrogen Replacement Therapy
;
Female
;
Femur
;
Humans
;
Korea
;
Leg
;
Linear Models
;
Menopause*
7.The effects of bilateral oophorectomy and estrogen replacement therapy on dynamic changes of serum pituitary gonadotropin and estrogen levels in premenopausal women.
Dai Won SEO ; Hyoung Moo PARK ; Do Hwan BAE
Korean Journal of Obstetrics and Gynecology 1993;36(11):3696-3706
No abstract available.
Estrogen Replacement Therapy*
;
Estrogens*
;
Female
;
Gonadotropins*
;
Humans
;
Ovariectomy*
10.A case of myasthenia gravis in pregnancy.
Byeong Jun CHEONG ; Hyoung Moo PARK ; Do Hwan BAE
Korean Journal of Obstetrics and Gynecology 1992;35(6):932-940
No abstract available.
Myasthenia Gravis*
;
Pregnancy*