No abstract available.

There are many classifications for idiopathic scoliosis but none of these is perfect. In the treatment of idiopathic scoliosis, it is essential to understand the characteristics of each classification system and exploit their individual advantages.
Classification* ; Scoliosis*

OBJECTIVE: A common cause of failure in laminectomy surgery is when epidural, peridural, or perineural adhesion occurs postoperatively. The purpose of this study is to examine the efficacy of a temperature-sensitive, anti-adhesive agent (TSAA agent), Guardix-SG®, as a mechanical barrier for the prevention or reduction of peridural scar adhesion in a rabbit laminectomy model. METHODS: Twenty-six mature rabbits were used for this study. Each rabbit underwent two separate laminectomies at lumbar vertebrae L3 and L6, left empty (the control group) and applied 2 mL of the TSAA agent (the experimental group), respectively. Invasive scar formation or inflammation after laminectomy was quantitatively evaluated by measuring the thickness of the dura, the distance from the surface of dura to the scar tissues, the number of inflammatory cells in the scar tissues at the laminectomy site, and the concentration of collagen in histological sections. RESULTS: At 6 weeks postsurgery, the dura was significantly thinner and the distance from the surface of dura to the scar tissues was greater in the experimental group than in the control group (p=0.04 and p=0.01). The number of inflammatory cells was not significantly different in the two groups (p=0.08), although the mean number of inflammatory cells was relatively lower in the experimental group than in the control group. CONCLUSION: The current study suggests that the TSAA agent, Guardix-SG®, could be useful as an interpositional physical barrier after laminectomy for the prevention or reduction of adhesion.
Cicatrix ; Collagen ; Inflammation ; Laminectomy* ; Lumbar Vertebrae ; Rabbits

Abdominal pregnancy is a rare entity, which has been classified as primary or secondary by Studifford criteria. The clinical characteristics of abdominal pregnancy is extremely variable, so early diagnosis is very difficult. Because of it's high maternal morbidity and mortality, the prompt surgical intervention is required. We experienced a primary abdominal pregnancy with intraperitoneal hemorrhage. So we present our case with a brief review of literature.
Early Diagnosis ; Female ; Hemorrhage* ; Mortality ; Pregnancy ; Pregnancy, Abdominal*

BACKGROUND/AIMS: The diagnostic value of PET-CT, in gastric cancer is well known, but the prognostic value of pretreatment PET-CT has not been adequately evaluated. This study aimed to investigate the preoperative prognostic value of PET-CT in gastric cancer patients. METHODS: A total of 107 patients underwent surgical treatment for gastric cancer from April 2007 to December 2010 at Dong-A University Medical Center after confirming the presence of F-18 fluorodeoxyglucose (FDG) uptake on preoperative PET-CT. Among these patients, the following subjects were excluded: follow-up loss (13), palliative resection (5), neoadjuvant chemotherapy (1), and unrelated death (1). The remaining 87 patients were included in this study and data were collected by retrospectively reviewing the medical records. The median follow-up duration, defined as the period from operation to last imaging study date, was 34.2+/-14.8 months. FDG uptake values were represented by maximal standardized uptake value (SUVmax). In order to assess the correlation between SUVmax and recurrence, Kaplan-Meier's survival analysis with log-rank test and cox proportional hazard model were performed. Receiver operating characteristic (ROC) curve was employed to determine the optimal cutoff value of SUVmax. RESULTS: The result of Kaplan-Meier's survival analysis with log-rank test were significantly different between high SUVmax group and low SUVmax group (p=0.035), the cutoff value of which was 5.6. However, in multivariate analysis with cox proportional hazard model, T-staging, N-staging and SUVmax did not show statistical significance (p=0.190, p=0.307, and p=0.436, respectively). CONCLUSIONS: High SUVmax on PET-CT in gastric cancer can be a useful prognostic factor.
Adult ; Aged ; Area Under Curve ; Female ; Fluorodeoxyglucose F18 ; Follow-Up Studies ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Neoplasm Grading ; Neoplasm Staging ; Positron-Emission Tomography ; Prognosis ; Proportional Hazards Models ; ROC Curve ; Radiopharmaceuticals ; Retrospective Studies ; Risk Factors ; Stomach Neoplasms/*diagnosis/mortality/surgery ; Tomography, X-Ray Computed

BACKGROUND/AIMS: The diagnostic value of PET-CT, in gastric cancer is well known, but the prognostic value of pretreatment PET-CT has not been adequately evaluated. This study aimed to investigate the preoperative prognostic value of PET-CT in gastric cancer patients. METHODS: A total of 107 patients underwent surgical treatment for gastric cancer from April 2007 to December 2010 at Dong-A University Medical Center after confirming the presence of F-18 fluorodeoxyglucose (FDG) uptake on preoperative PET-CT. Among these patients, the following subjects were excluded: follow-up loss (13), palliative resection (5), neoadjuvant chemotherapy (1), and unrelated death (1). The remaining 87 patients were included in this study and data were collected by retrospectively reviewing the medical records. The median follow-up duration, defined as the period from operation to last imaging study date, was 34.2+/-14.8 months. FDG uptake values were represented by maximal standardized uptake value (SUVmax). In order to assess the correlation between SUVmax and recurrence, Kaplan-Meier's survival analysis with log-rank test and cox proportional hazard model were performed. Receiver operating characteristic (ROC) curve was employed to determine the optimal cutoff value of SUVmax. RESULTS: The result of Kaplan-Meier's survival analysis with log-rank test were significantly different between high SUVmax group and low SUVmax group (p=0.035), the cutoff value of which was 5.6. However, in multivariate analysis with cox proportional hazard model, T-staging, N-staging and SUVmax did not show statistical significance (p=0.190, p=0.307, and p=0.436, respectively). CONCLUSIONS: High SUVmax on PET-CT in gastric cancer can be a useful prognostic factor.
Adult ; Aged ; Area Under Curve ; Female ; Fluorodeoxyglucose F18 ; Follow-Up Studies ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Neoplasm Grading ; Neoplasm Staging ; Positron-Emission Tomography ; Prognosis ; Proportional Hazards Models ; ROC Curve ; Radiopharmaceuticals ; Retrospective Studies ; Risk Factors ; Stomach Neoplasms/*diagnosis/mortality/surgery ; Tomography, X-Ray Computed

STUDY DESIGN: Retrospective study. OBJECTIVE: To compare patients who underwent spinal revision surgery of adjacent segment degeneration with above one and above two vertebral segment preceded by initial spinal fusion surgery. SUMMARY OF LITERATURE REVIEW: The adjacent segment disease(ASD) occurs more frequently at the more proximal segment of the spinal fusion. Also, the preexisting degenerative segments (with discs or facet joints) not included in the fusion procedure, fusion segmental sagittal angle, fixed appliances method, gender, and age, have been accepted as the causes. MATERIALS AND METHODS: The patients were watched over a year after the spinal revision operation followed by initial spinal fusion of single or multiple segments; the subjects were limited to 41 patients. The average age, entity of diseases, average duration between the initial spinal fusion and the revision surgery, multiple clinical and radiographic parameters were evaluated and compared. RESULTS: Using the UCLA grade of intervertebral disc degeneration, the average grade of 1 level upper segment was 2.2 in group A and 1.9 in group B without statistical significance(p=0.426). However, the average grade of 2-level upper segment was 1.8 in group A and 2.4 in group B with significant difference(p=0.021). There was no statistical difference in other factors between the two groups. CONCLUSIONS: Patients with ASD of above two-vertebral segment after spinal fusion were more severe in disc degeneration than those with ASD of above one vertebral segment before initial spinal fusions.
Humans ; Intervertebral Disc Degeneration ; Retrospective Studies ; Spinal Fusion*

Recently, increased emphasis has been placed on the need for rehabilitation professionals to objectively evaluate a patient's potential for and progress toward a return to normal function. But as medical recovery nears completion, additional questions are commonly asked by physicians regarding work function and ability to return to full active employment. In the past, therapists have attempted to reestablish the work situation using real tools, but these machines were expensive, have space limitations and in some cases, potentially dangerous as well. A Baltimore Therapeutic Equipment(BTE) Work Simulator overcomes these shortcomings. It can be used for isometric and isotonic evaluation and treatment and assisted in providing the information needed to make determinations regarding progress in therapy, return-to-work status and job modifications. We are going to obtain normative isometric, dynamic and endurance of grip strength, key pinch strength and three point pinch strength data using BTE Work Simulator model WS20. We also compare these data between ages and sexs. This study will be helpful in clinical applications of the BTE Work Simulator and providing the more specific job related occupational therapy and developing special vocational rehabilitation program.
Employment ; Hand Strength* ; Occupational Therapy ; Pinch Strength* ; Rehabilitation ; Rehabilitation, Vocational ; Return to Work

We report on an unusual case of primary extranodal non-Hodgkin's lymphoma of the sphenoid sinus invading cavernous sinus. A 69-year-old male patient presented with left facial pain and headache. A nasal endoscopy revealed no specific finding in both nasal cavity and no definite mass like lesion was found in the nasal cavity. Paranasal CT scans demonstrated mild haziness without bony erosion or thinning in left sphenoid sinus. Several months later, he complained of a ptosis and lateral gaze palsy of the left eye when he gazed at the left side. Brain MRI showed a well enhanced lobulated mass in the left sphenoid sinus invading into the left carvenous sinus and middle cranial fossa with left internal carotid artery encasement. Endoscopic biopsy via transnasal sphenoidotomy was performed under general anesthesia, and an easy fragile, yellowish, reddish mass in the sphenoid sinus was partially removed. The mass had infiltrated into the lateral, inferior and superior wall of the left sphenoid sinus. Biopsy confirmed a diffused large B-cell lymphoma. First, the patient received gamma knife radiosurgery, followed by chemotherapy (rituximab, cyclophosphamide, adriamycin, vincristine, prednisolone). He has been in complete remission state for eight months after combination therapy.
Aged ; Anesthesia, General ; B-Lymphocytes* ; Biopsy ; Brain ; Carotid Artery, Internal ; Cavernous Sinus* ; Cranial Fossa, Middle* ; Cyclophosphamide ; Doxorubicin ; Drug Therapy ; Endoscopy ; Facial Pain ; Headache ; Humans ; Lymphoma ; Lymphoma, B-Cell* ; Lymphoma, Non-Hodgkin ; Magnetic Resonance Imaging ; Male ; Nasal Cavity ; Paralysis ; Radiosurgery ; Sphenoid Sinus* ; Tomography, X-Ray Computed ; Vincristine

BACKGROUND AND OBJECTIVES: Although exposure to cigarette smoke has been reported to be associated with olfactory dysfunction, the pathophysiology is poorly understood. The purpose of this study is to evaluate the histopathological change of olfactory epithelium according to exposure duration of cigarette smoke and to investigate the effects of cigarette smoke on the olfactory epithelium. SUBJECTS AND METHOD: Thirty-six healthy Sprague-Dawley rats were divided into 2 groups. Experimental groups (n=28) were exposed to cigarette smoke during 2.5 hours (total 5 cigarettes) per one day for 5 days, 11 days and 3, 4, 5, 6, 9 weeks. Control group (n=8) was placed at the same room without smoke exposure and sacrificed at 4 and 9 weeks. Histopathological changes of olfactory epithelium through light microscope and immunohistochemistric findings of olfactory marker protein (OMP) through confocal microscope were observed. The numbers of cells in olfactory epithelium were counted at each period. RESULTS: From 5 days of cigarette smoke exposure, defection of epithelial cells, random arrangement of olfactory receptor cells and decreased thickness of olfactory epithelium were noticed. Numbers of olfactory receptor cells were significantly decreased at 11 days and 3 weeks after smoke exposure, and this finding of decreased number of olfactory receptor cells were continued until 9 weeks of exposure. Numbers of OMP-positive olfactory receptor cells were continuously decreased according to exposure duration. CONCLUSION: The olfactory epithelial cells could be directly affected by cigarette smoke. The numbers of olfactory epithelial cells including olfactory receptor cells were continuously decreased until 9 weeks after cigarette smoke exposure.
Animals ; Epithelial Cells ; Olfactory Marker Protein ; Olfactory Mucosa* ; Pathology ; Rats* ; Rats, Sprague-Dawley ; Smoke* ; Smoking ; Tobacco Products*