Allogenic bone marrow chimera has been used to study the differentiation of donor-derived bone marrow cells under the recipient thymic environment, tolerance generaion between recipient and donor cells. We prepared H-2' to H-2 allogenic chimera by transfering bone marrow cells from H-2dmice to r-irradiated H-2k mice, and examined the differentiation ofthe bone marrow cells under allogenic environment. Complete reconstitution with H-2d+ phenotype cells in the thymus of the chimera mice was observed. However, the number of CD4- CD8+ cells dramatically decreased under the recipient thymic environment, CD8+ cells significantly reduced also in spleen and lymph node, compared with that of normal mice. Interestingly, we also observed coexistence of donor-derived cells (H-2k) and recipient derived cells (H-2d) in lymph node and spleen in the chimera. These results suggested that the decrease of CD4-CD8+ cells could be caused by r-irradiation by affecting the recipient thymic environment, and that in this chimera, tolerance between donor-derived cells and recipient-derived cells was maintained.
Animals ; Bone Marrow Cells ; Bone Marrow* ; Chimera* ; Humans ; Lymph Nodes ; Mice ; Phenotype ; Spleen ; Thymus Gland ; Tissue Donors

No abstract available.

No abstract available.

We studied the left ventricular function with the use of M-mode and 2-D Echocardiography to 32 patients with congestive heart failure before and 2 weeks after medication of prazosin 2 mg tid during July 1979 and Dec. 1980 in Heart Center, Paik Hospital, In-Je Medical College, Busan, Korea. The results were following; 1) LVDeD before and after vasodilaor therapy was each 5.64+/-0.76 and 5.04+/-0.57.cm, LVSeD before and after therapy each 4.52+/-0.51 and 3.70+/-0.57cm, and F.S. before and after therapy 19.87+/-3.66 and 26.59+/-6.75%. The difference of LVSeD, LVDeD and F.S. was each statistically significant. 2) LVDeV before and after therapy was each 182.2+/-58.07 and 132.80+/-47.01 ml LVSeV before and after therapy each 92.35+/-23.60 and 50.65+/-27.21ml, and E.F. before and after therapy each 49.31+/-7.07 and 61.86+/-11.74%. The difference of LVDeV, LVSeV and E.F. was each statisitically significant. 3) LVPWTh before and after therapy was each 0.89+/-0.11 and 0.77+/-0.08cm, and Vcf before and after therapy 0.83+/-0.11 and 1.03+/-0.27 cir./sec. The difference of LVPWTh and vcf before and after therapy was each statistically significant. 4) The difference of VSTh, RVD, LAD, and Aorta Dimension before and after therapy was each statisitically significant.
Aorta ; Busan ; Echocardiography* ; Estrogens, Conjugated (USP)* ; Heart ; Heart Failure* ; Heart Ventricles* ; Humans ; Korea ; Prazosin ; Ventricular Function, Left

There are few reports in the literature on how to care and manage bi!ateral congenital dislocation of the hip. Six patients have been encountered at this hospital from June 1979, of them four children had operative treat ment and the other two conservative. As a result of our experience about the management of bilateral congenital dislocation of the hip. The authors obtained the following conceptions; 1. The patient with bilateral dislocation was rather delayed in diagnosis. Therefore, in comp the treatment of bilateral cases was poorer than that of unilateral case. 2. In the case of the dislocated hip that might be easily reduced and maintained in the stab servative care was usually recommeded even in the older child. Unstable, unreduced hip,; hip in old children, the more definitive operation and internal & external rigid immobilization mandatory to get good result. 3. It might be beneficial to operate the more deformed and resistive hip first, and then to p with the same procedure 2 weeks after the first operation.
Child ; Diagnosis ; Dislocations ; Fertilization ; Hip ; Humans ; Immobilization

No abstract available.
Dacarbazine*

No abstract available.
Leukemia, Neutrophilic, Chronic*

While oral and maxillofacial surgery such as orthognathic surgery, TMJ surgery is in progress, there always exists a risk of bleeding from maxillary artery, and this perplexes the surgeon in operation. In case of massive bleeding, it is mostly very difficult or even impossible to take an immediate action in order to stop bleeding. Even when hemostasis is possible by applying such methods as the use of local hemostatics, pressing, electrocoagulation or direct ligation, there is a high risk of secondary bleeding. Therefore, in case there is bleeding from maxillary artery, it is the best to restrain bleeding completely either by the ligation of the artery in bleeding in operation fields or by the ligation of the external carotid artery.
Arteries ; Carotid Artery, External ; Electrocoagulation ; Hemorrhage* ; Hemostasis ; Hemostatics ; Ligation ; Maxillary Artery ; Orthognathic Surgery ; Surgery, Oral ; Temporomandibular Joint

Changes of human pulse rates are influenced by psychological factor as well as systemic disease. Pulse rates tend to increase in the state of fear, pain, anxiety, and excitement. We performed this study for the evaluation of psychological state during the surgical extraction of mandibular impacted 3rd molar. Total 42 patients without systemic compromised condition were selected and pulse rates were checked with pulse oximeter(Nellcor, N-180) during the initial sitting state at dental unit chair, local anesthesia, draping and operation(5-minute interval). Male patients were 22, female 20. Age ranged from 13 to 57, with a mean of 26.9. Operative time(from incision to end of suture) ranged from 4 minutes to 32 minutes, with a mean of 11.1 minutes. The most significant elevation of pulse rates were observed during draping, the next at 10 minutes after incision(P< 0.05). Elevation of pulse rates during the anesthesia was not more than preoperative state and variable(P> 0.05).
Anesthesia ; Anesthesia, Local ; Anxiety ; Female ; Heart Rate* ; Humans ; Male ; Molar* ; Psychology

Chronic Periodontitis ; Female ; Humans ; Male ; Mucocele ; Surgery, Oral ; Temporomandibular Joint Disorders