A study of concentration smear, culture for AFB and sensitivity test for antituberculous drugs was carried out in 810 patients who had been admitted in SNUH in the period of 12 months from January 1976 to December 1976. Acid-fast bacilli was confirmed in 110 cases (13.6%) by concentrated direct smear and in 88 cases(10.9%) by culture, and concomitantly sensitivity test was performed in 26 isolated cases. Streptomycin, INH, PAS, Kanamycin and Ethionamide were rather less sensitive to the strains of Mycobacterium tuberculosis, but all strains obtained during the period of this study were highly sensitive to Rifampicin.
Ethionamide ; Humans ; Kanamycin ; Mycobacterium tuberculosis ; Mycobacterium ; Rifampin ; Streptomycin

Tureta and his colleagues have stressed the important role that vessels play in osteogenesis. Numerous arthors attempted to provide new bone formation by placing vascular pedicles into the bone. Some reports are convining, but experimental model and histological investigation leave something yet to learn. We conducted an experiment to demonstrate the feasibility of using a vascular bundle to create new bone formation in medullary canal. Vasculsr bundle of the femoral artery and vein was transplanted in same side of the femoral canal of rabbits. The transplanted vascular bundle was studied histologically for eight weeks. At 3 weeks transplanted artery started proliferation of intima and media, and its lumen was obliterated completely at 6 weeks. Transplanted vein collapsed from begining, and didn't involve in revascularization and new bone formation. At 2 weeks the proliferation of capillaries promoting revascularization originated from the adventitia of the transplanted artery, and peaked at 6 weeks. New osteoid appeared around the transplanted vessel at 2 weeks, and surrounded the entire vessel in 5 weeks, and had no more progression in amount at 6 weeks. Cortical hypertrophies showed in the vascular bundle transplanted group from 3 weeks. Examination of control group revealed no sign of new osteoid formation around the hole during the whole study period.
Adventitia ; Arteries ; Capillaries ; Femoral Artery ; Hypertrophy ; Models, Theoretical ; Osteogenesis ; Rabbits ; Veins

No abstract available.
Diabetic Foot*

In the treatment of dislocations and subluxations of the hip in the older children, whether congenital or paralytic, orthopedic surgeons are blessed with a wide variety of commonly used surgical procedures; namely, Salters innominate osteotomy, acetabtloplasties, Pembertons pericapsular osteotomy, shelf operations, Chiaris pelvic displacement osteotomy. and Colonnas capsular arthroplasty. However, with increasing age and soft tissue contractures,these procedures become ineffective, leaving a wide range of age between older children and young adults subject to uncertain or unfavarable prognosis. Steels triple osteotomy (1973) is aimed at coverig this age group, when displacement or in nominate osteotomy is either technically infeasible or likely to fail. It consists of an open reduction with or without soft tissue release and skeletal traction, redirection of the acetabulum to cover the femoral head by osteotonmies of the pelvis that has lost its young cartilagenous resiliency, and preservation and physiological remodelling of the articular cartilage of the acetabulum. We performed Steels osteotomy on a 21-years-old female with a severe paralytic subluxation of the hip associated with pelvic obliquity and paralytized both lower extremities. One and a half year follow-up result was satisfactory with a stable and congruous joint despite paralysis and with the patient walking for the first time in her life.
Acetabulum ; Adult ; Arthroplasty ; Cartilage, Articular ; Child ; Dislocations ; Female ; Follow-Up Studies ; Head ; Hip ; Humans ; Joints ; Lower Extremity ; Orthopedics ; Osteotomy ; Paralysis ; Pelvic Bones ; Pelvis ; Prognosis ; Steel ; Surgeons ; Traction ; Walking ; Young Adult

Clinical observation of thirty-eight cases of pyogenic osteomyelitis of the spine for the period of eleven years, from 1965, at Seoul National University Hospital was carried out with the following results. 1. The incidence of pyogenic osteomyelitis of the spine among total cases of the pyogenic osteomyelitis was 6.9% and the ratio between the spine tuberculosis and the pyogenic osteomyelitis of the spine was 1:0.067. 2. The sex ratio between male and female wss 3.8: 1 The incidence was higher ia the second and third decade and the average prevalent age was 30.8 years of age. 3. The site of infection was in the lumbar vertebrae in 25 cases(66%), thoracic in seven(19%), lumbosacral in three, sacral in two and cervical in one. In the region of a vertebra, the vertebral body was affected in 33 cases (87%) and the neural arch and processes in other 5 cases (13%) 4. The causative micro-organism was isolated in 27 cases from the diseased focus; coagulase positive staphylococcus in 18 cases (67%), streptococcus in one, salmonella in one and the mixed infection in two. 5. Frequent clinical symptoms and signs were back pain, tenderness, muscle spasm, fever and chillness, and limited motion of the spine. 6. The roetgenographic findings were in order of disc space narrowing, destruction of the vertebral body, kyphosis or loss of lordosis, erosion, bony bridging or spur formation, sclerosis and paravertebral abscess. 7. The conservative treatment was performed in 14 cases. Among 7 cases in which the follow-up was possible, only 3 cases obtained the satisfactory result, four cases were readmitted for the recurrence and two cases among them needed the operative treatment later. The operative treatment was peformed in 26 cases; The focal curettage with anterior interbody fusion through anterior approach was carried out in 13 cases with the satisfactory result in almost all cases. 8. The advantages of the operative treatment were that the isolation of the offending organism was efficient and the definite diagnosis was feasible, and especially in cases of anterior spinal fusion the healing and union of the infected spine was better clinically and roetgenographically in comparision with those of conservative treatment, in which the expected spontaneous fusion was not found in any case and the recurrence was also frequent.
Abscess ; Animals ; Back Pain ; Coagulase ; Coinfection ; Curettage ; Diagnosis ; Female ; Fever ; Follow-Up Studies ; Humans ; Incidence ; Kyphosis ; Lordosis ; Lumbar Vertebrae ; Male ; Myalgia ; Osteomyelitis ; Recurrence ; Salmonella ; Sclerosis ; Seoul ; Sex Ratio ; Spasm ; Spinal Fusion ; Spine ; Staphylococcus ; Streptococcus ; Tuberculosis

Rickets is a syndrome, characterised pathophysiologically by a failure of normal mineralization of bone and epiphyseal cartilage and clinically by skeletal deformity in growing children. The four principal causes of rickets are; vitamin D deficency, renal tubular insufficiency, chronic renal insufficiency, and hypophosphatasia. Of these, vitamin D resistant rickets may result from primary defect in function of the renal tubular reabsorption for phosphorus, later accompsnied with secondary hyperparathyroidism. We experiened a rare case of hypophosphstemic vitamin D resistant rickets accompanied with secondary hyperparathyroidism in adolescence.
Adolescent ; Child ; Congenital Abnormalities ; Familial Hypophosphatemic Rickets ; Growth Plate ; Humans ; Hyperparathyroidism, Secondary ; Hypophosphatasia ; Miners ; Phosphorus ; Renal Insufficiency, Chronic ; Rickets ; Vitamin D ; Vitamins

The function of the meniscus and subsequently the importance of meniscus preservation are well known. Thirty-two patients who underwent arthroscopic meniscus repair between 1993 and 1995 were studied retrospectively. Twenty menisci were repaired using modified Henning inside-out technique and the remaining twelve meaisci, outside-in technique. The average delay in surgery was two hundred days. Follow-up was done from 1 year to 3 years (average 22.4 months). The medial meniscus was repaired in 22 cases and the lateral meniscus including two saucerized discoid meniscus in 10 cases. Fourteen patients had anterior cruciate ligament (ACL) tear and other associated knee injuries were lateral condyle fra'cture of femur in one case and lateral condyle &acture of tibia in one case. Assessment of the result was based on the evaluation form of the International Knee Documentation CommitteegKDC). Twenty-seven patients (84.3%) were normal to nearly normal. Abnormal and severely abnormal results were mainly affected by the result of treatment of ACL tear.
Anterior Cruciate Ligament ; Femur ; Follow-Up Studies ; Humans ; Knee ; Knee Injuries ; Menisci, Tibial ; Retrospective Studies ; Tibia

Treatment for the femoral shaft fractures in adolescents is somewhat controversial. These fractures have been treated nonoperatively, but adolescents tolerate prolonged immobilization less well than younger children and conservative treatment in this age group may result in more complicationssuch as malunion, shortening and angular deformities more often than those in the younger age group. Recently there has been a tendency to choose the operative method rather than traditional traction and casting technique for femoral shaft fractures in elderly children and adolescent The purpose of this study is to find better treatment for the femoral shaft fractures in adolescents. Fifty six femoral shaft fractures in 56 patients aged 10 to 14 years old were treated with traction followed by casting, open reduction and internal fixation with plate, closed intramedullary nailing, or external fixation using A-0 external fixator, and evaluated respectively for at least 1 year. External fixation may be benefit to patients with concomittant injuries and result in psychological settle down, early mobilization out of bed, short hospital stay, save of cost,and early return to daily living activities without any disadvantages such as malunion, leg length discrepancy or awareness of growing arrest in spite of negligible pin tract infection. Result of this study suggests that external fixation for the femoral shaft fractures may be an one of the attractive treatment option in adolescents.
Activities of Daily Living ; Adolescent* ; Aged ; Child ; Congenital Abnormalities ; Early Ambulation ; External Fixators ; Fracture Fixation, Intramedullary ; Humans ; Immobilization ; Leg ; Length of Stay ; Traction

No abstract available.
Epidemiology* ; Hip Fractures* ; Hip*

No abstract available.
Analgesia*