1.Gastric Cancer and Concomitant Gastric Tuberculosis: A Case Report.
Hyok Jo KANG ; Young Seok LEE ; You Jin JANG ; Young Jae MOK
Journal of Gastric Cancer 2012;12(4):254-257
Gastric tuberculosis is rare even in the endemic areas of tuberculosis, and can mimic neoplasm by causing elevation of the mucosa with or without ulceration. Here, we report a case in which a 54-year-old female patient admitted for resection of early gastric cancer was found to have coexisting histopathologically and bacteriologically confirmed gastric cancer and tuberculosis.
Female
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Humans
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Hydrazines
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Mucous Membrane
;
Stomach Neoplasms
;
Tuberculosis
;
Tuberculosis, Gastrointestinal
;
Ulcer
2.Gastric Cancer and Concomitant Gastric Tuberculosis: A Case Report.
Hyok Jo KANG ; Young Seok LEE ; You Jin JANG ; Young Jae MOK
Journal of Gastric Cancer 2012;12(4):254-257
Gastric tuberculosis is rare even in the endemic areas of tuberculosis, and can mimic neoplasm by causing elevation of the mucosa with or without ulceration. Here, we report a case in which a 54-year-old female patient admitted for resection of early gastric cancer was found to have coexisting histopathologically and bacteriologically confirmed gastric cancer and tuberculosis.
Female
;
Humans
;
Hydrazines
;
Mucous Membrane
;
Stomach Neoplasms
;
Tuberculosis
;
Tuberculosis, Gastrointestinal
;
Ulcer
3.Different Patterns of Risk Reducing Decisions in Affected or Unaffected BRCA Pathogenic Variant Carriers.
Eun Gyeong LEE ; Hyok Jo KANG ; Myong Cheol LIM ; Boyoung PARK ; Soo Jin PARK ; So Youn JUNG ; Seeyoun LEE ; Han Sung KANG ; Sang Yoon PARK ; Boram PARK ; Jungnam JOO ; Jai Hong HAN ; Sun Young KONG ; Eun Sook LEE
Cancer Research and Treatment 2019;51(1):280-288
PURPOSE: The purpose of this study was to investigate decision patterns to reduce the risks of BRCArelated breast and gynecologic cancers in carriers of BRCA pathogenic variants. We found a change in risk-reducing (RR) management patterns after December 2012, when the National Health Insurance System (NHIS) of Korea began to pay for BRCA testing and riskreducing salpingo-oophorectomy (RRSO) in pathogenic-variant carriers. MATERIALS AND METHODS: The study group consisted of 992 patients, including 705 with breast cancer (BC), 23 with ovarian cancer (OC), 10 with both, and 254 relatives of high-risk patients who underwent BRCA testing at the National Cancer Center of Korea from January 2008 to December 2016.We analyzed patterns of and factors in RR management. RESULTS: Of the 992 patients, 220 (22.2%) were carriers of BRCA pathogenic variants. About 92.3% (203/220) had a family history of BC and/or OC,which significantly differed between BRCA1 and BRCA2 carriers (p < 0.001). All 41 male carriers chose surveillance. Of the 179 female carriers, 59 of the 83 carriers (71.1%) with BC and the 39 of 79 unaffected carriers (49.4%) underwent RR management. None of the carriers affected with OC underwent RR management. Of the management types, RRSO had the highest rate (42.5%) of patient choice. The rate of RR surgery was significantly higher after 2013 than before 2013 (46.3% [74/160] vs. 31.6% [6/19], p < 0.001). CONCLUSION: RRSO was the preferred management for carriers of BRCA pathogenic variants. The most important factors in treatment choice were NHIS reimbursement and/or the severity of illness.
Breast
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Breast Neoplasms
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Female
;
Humans
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Korea
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Male
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National Health Programs
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Ovarian Neoplasms
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Prophylactic Surgical Procedures