3.A Case of Gaucher's Disease.
Hyo Nam CHO ; Myung Cheol CHO ; Hyung Ro MOON ; Je Geun CHI ; Hyo Min KIM
Journal of the Korean Pediatric Society 1987;30(7):784-790
No abstract available.
Gaucher Disease*
4.Modulatory effects of the fruits of Tribulus terrestris L. on the function of atopic dermatitis-related calcium channels, Orai1 and TRPV3
Nam Hyun Joo ; Jung Won Hyo ; Chin Young-Won ; Kim Kyung Woo ; Bae Sang Hyo
Asian Pacific Journal of Tropical Biomedicine 2016;6(7):580-585
Objective: To examine the effects of Tribulus terrestris L. (T. terrestris) extract on the modulation of calcium channels to evaluate its use in topical agents for treatment of atopic dermatitis. Methods: The 70% methanol extract of T. terrestris was prepared. Human HEK293T cells with over-expressed calcium release-activated calcium channel protein 1 (Orai1), transient receptor potential vanilloid 1, or transient receptor potential vanilloid 3 (TRPV3) were treated with T. terrestris extract. Modulation of ion channels was measured using a conventional whole-cell patch-clamp technique. Results: T. terrestris extract (100 mg/mL) significantly inhibited Orai1 activity in Orai1-stromal interaction molecule 1 co-overexpressed HEK293T cells. In addition, T. terrestris extract significantly increased the TRPV3 activity compared with 2-Aminoethyl diphe-nylborinate (100 mmol/L), which induces the full activation of TRPV3. Conclusions: Our results suggest that T. terrestris extract may have a therapeutic po-tential for recovery of abnormal skin barrier pathologies in atopic dermatitis through modulating the activities of calcium ion channels, Orai1 and TRPV3. This is the first study to report the modulatory effect of a medicinal plant on the function of ion channels in skin barrier.
5.Awareness and Performance on Standard Precautions of Hospital-acquired Infection Control in Nursing Students: The Mediating Effect of Internal Health Locus of Control.
Journal of Korean Academic Society of Nursing Education 2017;23(4):378-388
PURPOSE: The aim of this study was to identify the status of performance on standard precautions among nursing students and to examine the mediating effects of internal health locus of control on the relationship between awareness and performance on standard precautions of hospital-acquired infection control. METHODS: The participants in this study were 134 nursing students. The measurements included a standard precautions awareness and performance scale, and a multidimensional health locus of control scale. Data were analyzed using independent t-test, one-way ANOVA, Scheffé test, Pearson correlation coefficient, and simple and multiple regression techniques. Mediation analysis was performed by the Baron and Kenny's method and Sobel test. RESULTS: The mean score of standard awareness, standard performance, and internal health locus of control about standard precaution were 174.30±9.08; 169.48±12.04; and 20.43±2.82; respectively. There was a positive correlation between standard awareness and performance (r=.414, p<.001). Also, standard awareness was significantly correlated with internal health locus of control (r=.413, p=.014). Internal health locus of control showed partial mediating effects in the relationship between awareness and performance. CONCLUSION: The results indicate a need to improve the internal health locus of control of nursing students. Therefore, an internal health locus of control improvement program should improve performance on standard precautions for patients and themselves.
Cross Infection
;
Humans
;
Infection Control*
;
Internal-External Control*
;
Methods
;
Negotiating*
;
Nursing*
;
Students, Nursing*
;
Universal Precautions
6.CT findings of orbital pseudotumor.
Min Yun CHOI ; Sang Hwa NAM ; Kun Il KIM ; Chang Hyo SOL ; Byung Soo KIM
Journal of the Korean Radiological Society 1992;28(3):327-331
To evaluate characteristic CT findings of orbital pseudotumor and to define differentialpoints from other pathology, the authors retrospectively reviewed CT of 19 patients who were prooen to have orbital pseudotumor by clinical course and, in some cases, biopsy. A variety of CT findings including extraocular muscle thickening(11 cases), streaky infiltration of retroorbital fat(11 cases), mass formation(10 cases), optic nerve thickening (6 cases), conjunctival thickening (5 cases), scleral thickening(4cases), enlarged lacrimal gland(4 cases) and destruction of orbital bone (2 cases) were observed. Thickening of the anterior portion and irregular margin were characteristic findings of extraocular muscle and optic nerve lesions. Mass formation predominantly occurs in the anterior portion of the orbit. In most cases more than two orbital structures are involved by lesion.
Biopsy
;
Humans
;
Optic Nerve
;
Orbit*
;
Orbital Pseudotumor*
;
Pathology
;
Retrospective Studies
8.A case of advanced mixed germ cell tumor.
Yoon Sung NAM ; Hyo Don SOHN ; Young Mi LEE ; Il Soo PARK ; Tae Ho LEE
Korean Journal of Obstetrics and Gynecology 1991;34(12):1788-1794
No abstract available.
Germ Cells*
;
Neoplasms, Germ Cell and Embryonal*
9.Utility of fine needle aspiration in patients with thyroid nodules classified by surgical pathology.
Hyo Youl KIM ; Nam Kyu KANG ; Soo Gyeong KIM ; Seong Joon KANG ; Hyeong Man KIM
Journal of Korean Society of Endocrinology 1993;8(3):318-325
No abstract available.
Biopsy, Fine-Needle*
;
Humans
;
Pathology, Surgical*
;
Thyroid Gland*
;
Thyroid Nodule*
10.An Effect of Health Promotion Program in Mid-life Women.
Keum Ja KIM ; Young Nam CHA ; Hye Kyung LIM ; Hyo Soon JANG
Journal of Korean Academy of Nursing 1999;29(3):541-550
The purpose of the study was to test the effect of the health promotion program in middle women. The research design was a quasi experimental, nonequivalent control-group pretest-posttest design. The data were collected from February 24 to April 14, 1988. The subjects were midlife women, age 40 to 50 years who reside in Chonju city. The experimental group consisted of 41 subjects and the control group 40 subjects. The instruments used for the study were the Self Efficacy Scale and the Health Promotion Behavior Scale developed by Park(1995). The data was analyzed by SPSS/PC. The study result were as follows: Through the 7 week education program for health promotion, self efficacy and health behavior were effectively changed in middle-aged.
Education
;
Female
;
Health Behavior
;
Health Promotion*
;
Humans
;
Jeollabuk-do
;
Research Design
;
Self Efficacy