In this study, we have conducted characterization of imaging performance for a flat panel digital X-ray detector using amorphous Selenium and a-Si TFT which was developed by the authors. The procedures for characterization were in concordance with internationally recommended standards such as IEC (international electrotechnical commission). The measures used for imaging performance characterization include response characteristic, modulation transfer function (MTF), detective quantum efficiency (DQE), noise power spectrum (NPS), and quantum limited performance. The measured DQEs at lowest and highest spatial frequencies were 40% and 25% respectively, which was superior to that of commercial products by overseas vendor. The MTF values were significantly superior to that of CR and indirect type DRs. The quantum limited performance showed the detector was limited by quantum noise at the entrance exposure level below 0.023 mR, which is sufficiently low for general X-ray examination.
Commerce ; Noise ; Selenium ; Silicon

The cytologic examination of the urine is very simple and inexpensive procedure for the detection and follow up the genitourinary tumors, and worthy as a mass screening test. The voided urines of 20 patients who were admitted to the department of urology, Seoul city hospital from October 1983 to September 1985 with the diagnosis of bladder carcinoma were analysed as to variations in PH and osmolality values and quality of cytologic smears. The same analyses were repeated after addition of trichloracetic acid (TCA) and after diuresis was obtained by Furosemide medication. Standardization of values of PH (average 2) and of osmolality (average 300 mosm/kg) was obtained by adding TCA to furosemide urine. The cellular smears of this TCA treated furosemide urine exhibited the finest cytological details when compared to the smears obtained by routine method.
Diagnosis* ; Diuresis ; Furosemide ; Hospitals, Urban ; Humans ; Hydrogen-Ion Concentration ; Mass Screening ; Osmolar Concentration ; Seoul ; Urinary Bladder ; Urology

One of the moot important goals of modem gynexologic oncology is the adequate management of ocarian cancer. This includes early detection and differenciation of recurrence or residurd turnur. A promising method is availaible today with the use of mctabolic suubstrates used by tumor cells that are labeled with positron emittillg isotopes and a special instrument capable of detecting the radiations in vivo. Measuring tumor metabolic characteristics appear also to diffnencinte tumor recurrence or reeidual tumor from surgical or irradiation changes which is important since this wil1 not be defferentiaited by other modalities such ac CT or MRI. The goal of this study was to rletennine the potential utility uf whole-body PET using the giucose malogue 2-(18F)-fluoro-2-deoxy-D-glucoae(F-18-FDO for the detection of primey, metastatic, and recurrent ovarian cancer. Six patients had imaging studies prior to laparotomy for suspected ovarian cancer. PET(Positron Emission Tomogrnphy) scans were done with an ECAT 921(Emission Computed Axial Tomograpy 921, Sieinens/CTI. The result of this study show good correla- tion between PET nnd pathological findirs. The tumor detection rate of CT, MRI, CA-125, PET for ocarian cancer was 50%, 75%, 25%, 100% respectively. In summary, this work indicates that PET may be useful in the rnanagement of patients with ovwrian cancers by idengying occult foci of rnetabolically active tumor that do not appear on morphological studies.
Electrons* ; Humans ; Isotopes ; Laparotomy ; Magnetic Resonance Imaging ; Modems ; Ovarian Neoplasms ; Recurrence

One of the moot important goals of modem gynexologic oncology is the adequate management of ocarian cancer. This includes early detection and differenciation of recurrence or residurd turnur. A promising method is availaible today with the use of mctabolic suubstrates used by tumor cells that are labeled with positron emittillg isotopes and a special instrument capable of detecting the radiations in vivo. Measuring tumor metabolic characteristics appear also to diffnencinte tumor recurrence or reeidual tumor from surgical or irradiation changes which is important since this wil1 not be defferentiaited by other modalities such ac CT or MRI. The goal of this study was to rletennine the potential utility uf whole-body PET using the giucose malogue 2-(18F)-fluoro-2-deoxy-D-glucoae(F-18-FDO for the detection of primey, metastatic, and recurrent ovarian cancer. Six patients had imaging studies prior to laparotomy for suspected ovarian cancer. PET(Positron Emission Tomogrnphy) scans were done with an ECAT 921(Emission Computed Axial Tomograpy 921, Sieinens/CTI. The result of this study show good correla- tion between PET nnd pathological findirs. The tumor detection rate of CT, MRI, CA-125, PET for ocarian cancer was 50%, 75%, 25%, 100% respectively. In summary, this work indicates that PET may be useful in the rnanagement of patients with ovwrian cancers by idengying occult foci of rnetabolically active tumor that do not appear on morphological studies.
Electrons* ; Humans ; Isotopes ; Laparotomy ; Magnetic Resonance Imaging ; Modems ; Ovarian Neoplasms ; Recurrence

BACKGROUND/AIMS: Many recent studies have shown excellent outcomes of surgical resection for ruptured hepatocellular carcinoma (HCC). In addition, there are several reports suggesting that a ruptured HCC did not increase the risk for peritoneal dissemination of a tumor after surgical resection. However, the impact of HCC rupture on recurrence and patient survival has not yet been clarified. METHODS: The medical data of patients who underwent surgical resection for ruptured HCC in our center between January 2011 and December 2015 were retrospectively reviewed. The outcomes of the patients were investigated. RESULTS: Among 128 patients who underwent surgical resection for HCC, 5 patients (3.9%) had a ruptured HCC. All patients underwent elective operation in a stable condition. Transarterial chemoembolization (TACE) was performed for achieving hemostasis in four patients except one who achieved spontaneous hemostasis. Two patients had tumor recurrence and one patient died due to HCC recurrence during the median follow-up duration of 28.3 months (range, 24.3–62.3 months). One patient who developed late intrahepatic recurrence at 40.0 months after resection was managed well by means of radiofrequency ablation and TACE and is now alive for 5 years without any evidence of viable tumor. However, the other patient who showed early peritoneal seeding at 1.9 months after resection finally died despite aggressive treatments. CONCLUSIONS: Rupture of HCC might result in peritoneal seeding of the tumor in the early postoperative stage, which could lead to a poor result. Nonetheless, surgical resection may be the best treatment option yielding good survival, even for a ruptured HCC.
Carcinoma, Hepatocellular* ; Catheter Ablation ; Follow-Up Studies ; Hemostasis ; Humans ; Recurrence ; Retrospective Studies ; Rupture

A case of Factor V deficiency, the first case in Korea, is reported in a 9-year-old boy whose plasma concentration of Factor V was 6%. He complained of easy bruisability, prolonged bleeding from the mouth after minor trauma and hemarthrosis and flexion contracture of the right knee. His parents are heterozygous (maternal Factor V concentration 52%, paternal 40%).
Child ; Factor V Deficiency/*congenital ; Humans ; Male

Hereditary ovarian cancer accounts for about 5% to 10% of the total ovarian cancer bnurden, The discase has been observed in context with three types of hereditary ovarian cancer prone syndrome : (1) site-specific ovarian cancer, (2) hereditary breast/ivarian cancer syndrome, (3) hereditary nonpolyposis colorectal cancer(Lynch syndrome II). Each of these syndmmcs is chracterized by autosomal dominant transmission of cancer, sigrdficant early age of onset, and exeess of multiple Iprimary cancers. Auuthor expxeriencecl six families with hereditaty ovarian cancer, two families with a site-spxific. ovarian cancer and four with a breast/ovarian cancer syndrome, and report these families.
Age of Onset ; Chymopapain ; Humans ; Ovarian Neoplasms*

Hereditary ovarian cancer accounts for about 5% to 10% of the total ovarian cancer bnurden, The discase has been observed in context with three types of hereditary ovarian cancer prone syndrome : (1) site-specific ovarian cancer, (2) hereditary breast/ivarian cancer syndrome, (3) hereditary nonpolyposis colorectal cancer(Lynch syndrome II). Each of these syndmmcs is chracterized by autosomal dominant transmission of cancer, sigrdficant early age of onset, and exeess of multiple Iprimary cancers. Auuthor expxeriencecl six families with hereditaty ovarian cancer, two families with a site-spxific. ovarian cancer and four with a breast/ovarian cancer syndrome, and report these families.
Age of Onset ; Chymopapain ; Humans ; Ovarian Neoplasms*

This study is undertaken to investigate the clinical effecte of Neutrogin(recornbinant human granulocyte-colony stimulatiing factor) in 25 patients with ovarian caneer who received two courses of CAP chemotherapy. In the first courae of chemotherapy as a contml course, all patients were treated with CAP chemotherapy alone and during the second course, Neutrogin was given at a dose of 2ug/kg/day subcutaneouely for 14 days 24 hours after completion of chemotherapy. Neutrogin significantly increaaed the nadir count of leukocyte and abaolute neutrophil and decreased tbe number of days per patient on which the absolute neutrophil count was 1,000/mm3 or less. The mean recovery time required for neutrophil to greater than l,500/mm3 after nadir were significantliy decreased in the seeond comse as compared with the first course. Each one patient exriened mild side effects of Neatrogin, such as fever, tene pain and malaise and rernovered without tretment. These results showed that Neutrogin is extremely effective and useful to treat chemotherapy indueed leukopenia and to accelerate the recovery from these complications.
Drug Therapy* ; Fever ; Granulocyte Colony-Stimulating Factor* ; Humans* ; Leukocytes ; Leukopenia ; Neutropenia* ; Neutrophils ; Ovarian Neoplasms

This study is undertaken to investigate the clinical effecte of Neutrogin(recornbinant human granulocyte-colony stimulatiing factor) in 25 patients with ovarian caneer who received two courses of CAP chemotherapy. In the first courae of chemotherapy as a contml course, all patients were treated with CAP chemotherapy alone and during the second course, Neutrogin was given at a dose of 2ug/kg/day subcutaneouely for 14 days 24 hours after completion of chemotherapy. Neutrogin significantly increaaed the nadir count of leukocyte and abaolute neutrophil and decreased tbe number of days per patient on which the absolute neutrophil count was 1,000/mm3 or less. The mean recovery time required for neutrophil to greater than l,500/mm3 after nadir were significantliy decreased in the seeond comse as compared with the first course. Each one patient exriened mild side effects of Neatrogin, such as fever, tene pain and malaise and rernovered without tretment. These results showed that Neutrogin is extremely effective and useful to treat chemotherapy indueed leukopenia and to accelerate the recovery from these complications.
Drug Therapy* ; Fever ; Granulocyte Colony-Stimulating Factor* ; Humans* ; Leukocytes ; Leukopenia ; Neutropenia* ; Neutrophils ; Ovarian Neoplasms