No abstract available.
Child* ; Herpes Zoster* ; Humans

No abstract available.
Child* ; Herpes Zoster* ; Humans

No abstract available.
Child* ; Cytarabine* ; Cytosine* ; Doxorubicin* ; Humans ; Leukemia, Myeloid, Acute* ; Maintenance Chemotherapy* ; Remission Induction* ; Thioguanine*

No abstract available.
Incidence* ; Leukemia*

No abstract available.
Child* ; Humans

No abstract available.
Pseudohypoaldosteronism*

No abstract available.
Flow Cytometry* ; Immunophenotyping* ; Precursor Cell Lymphoblastic Leukemia-Lymphoma*

No abstract available.

Idiopathic myelofibrosis (IMF), which is characterized by marrow fibrosis, leukoerythroblastic anemia, teardrop poikilocytosis and splenomegaly due to extrumedullary hematopoiesis, has known to have no form of therapy. On the ground of the possibility of reversing collagen deposion in IMF using 1, 25dihydroxycholecalciferol [1, 25(OH)2D3], we report here our observations of 5 patients (M:F=1:4) with IMF before and after treatment with 0.5 microgram/day of alfacalcidol, precursor of 1, 25(OH)2D3. In 3 fo 5 patients the hemoglobin rose and in 4 of 5 the platelet count increased. Follow-up marrow examination revealed that marrow trephine reticulin fibrosis decreased according as the amelioration of clinical and laboratory findings. But these did not persist except one patient in spite of the sustained use of alfacalcidol. Our results suggest that alfacalcidol may have a therapeutic role in some patients with IMF. More extensive studies will be clarify the action of alfacalcidol in IMF.
Anemia, Myelophthisic ; Bone Marrow ; Child* ; Collagen ; Fibrosis ; Follow-Up Studies ; Hematopoiesis ; Humans ; Platelet Count ; Primary Myelofibrosis* ; Reticulin ; Splenomegaly

No abstract available.
Child* ; Humans ; Leukemia, Myeloid, Acute* ; Typhlitis*