We performed a retrospective review on 32 patients(37 eyes) with the diagnosis of optic neuritis with follow-up more than 3 months, to determine its clinical characteristics in Korea. They consisted of 18 women and 14 men with a median age of 35.9 years. The initial visual acuity on presentation was variable from 1.2 to NLP, 84% of patients had at least 0.5 or better final visual acuity. Sixty-nine percent of the patients showed swollen disc and the remaining appeared normal in the affected eyes. Visual field examination revealed central or ceco-central scotoma in 17 eyes(48%) and other variable visual field defects. Visual evoked potential was abnormal in 89% of the examined eyes. Magnetic resonance imaging showed optic nerve enhancement in 48% and characteristic findings consistent with multiple sclerosis was seen in 6% of the examined subjects. This result suggests that the optic neuritis in Korea present with more papillitis than retrobulbar optic neuritis and multiple sclerosis is less commonly seen compared with previous reports of Caucasian optic neuritis.
Diagnosis ; Evoked Potentials, Visual ; Female ; Follow-Up Studies ; Humans ; Korea* ; Magnetic Resonance Imaging ; Male ; Multiple Sclerosis ; Optic Nerve ; Optic Neuritis* ; Papilledema ; Retrospective Studies ; Scotoma ; Visual Acuity ; Visual Fields

Proliferating trichilemmal tumor is one of rare benign tumors of the skin appendages, considering as hamartoma of the terminal hair follicle, isthmic segment of the outer root sheath. We report a case of numerous proliferating trichilemmal tumors admixed with ordinary trichilemmal cysts with femilial history in 64-year-old man. He has total 157 lesions, which are chiefly located in scalp (48), back (32), and also face, neck, trunk, extremities. Histologically, the tumor is composed of irregularly arranged and ansatomosed trabeculae, lobules, or sheets of proliferated trichilemmal squamous epithelium with peripheral palisading of the basaloid cells. Several layers of squamoid or ovoid cells have PAS-positive clear cytoplasm. And it also shows abrupt amorphous, trichilemmal keratinization. Some squamous eddies with mild cellular atypism are associated, but definite invasion or other evidence of the malignancy is not found. usual multiple trichilemmal cysts are admixed with tumor and occasionally exhibit connection between them.
Cysts ; Hamartoma

PURPOSE: Inferior oblique palsy is the least commonly isolated extraocular muscle palsy. We describe the clinical features and managements of 2 cases of traumatic inferior oblique palsy. METHODS: Two adult patients were presented with vertical diplopia and head tilt posture after head trauma. The subjects fulfilled the three-step test criteria, with a hypertropia that worsened on side gaze and head tilt away from the affected eye. They showed free forced duction to elevation in adduction. Both were treated by ipsilateral superior oblique tenotomy and contralateral superior rectus recession with adjustable suture technique. RESULTS: During postoperative 7 month observation, both patients demonstrated orthophoria in primary gaze. Our surgical procedures eliminated the diplopia and abnormal head tilt posture, thereby achieving satisfactory results.
Adult ; Craniocerebral Trauma ; Diplopia ; Head ; Humans ; Paralysis* ; Posture ; Strabismus ; Suture Techniques ; Tenotomy

Sarcoidosis is a chronic granulomatous disease of unknown cause characterized by widespread occurence of epithelioic cell. The authors experienced a case of sarcoidosis in 34-year-old female who has lacrimal gland enlargement, severe subcutaneous nodules and bilateral granulomatous uveitis. Histopathologic examination of the subcutaneous nodule of lid revealed sarcoidosis. In the course of corticosteroid therapy, subcutaneous nodules and enlarged lacrimal gland subsided gradually.
Adult ; Female ; Granulomatous Disease, Chronic ; Humans ; Lacrimal Apparatus ; Sarcoidosis* ; Uveitis*

No abstract available.
DNA* ; Lymphoproliferative Disorders*

No abstract available.
DNA* ; Lymphoproliferative Disorders*

Purpose: This study aimed to determine the effects of grit, nursing work environment, and job esteem on the intent to stay among military hospital nurses. Methods: This study employed a descriptive cross-sectional design. Data were collected from February 7 to 18, 2022 from 232 nurses working at four military hospitals under the Armed Forces Medical Command. The analysis was conducted using the SPSS/WIN 26.0 program, and descriptive statistics, t-test, ANOVA, Pearson coefficient correlations, and multiple regression analysis were performed. Results: Factors affecting the intent to stay included job esteem (β=.44, p<.001), total clinical experience of more than 10 years (β=.24, p=.001), and nursing work environment (β=.17, p=.009). Conclusion The results can be used to ensure personnel quality at military medical institutions and can contribute to improving patient safety and medical services. Further, nursing managers need to formulate and implement strategies to foster a positive nursing work environment.

Septo-optic dysplasia is diagnosed when optic nerve hypoplasia is combined with dysgenesis of the septum pellucidum and nearly two-thirds of them have hypothalamic-pituitary dysfunction. A number of these patients have schizencephaly and usually present seizures. The migrational disorders including schizencephaly, lissencephaly, heterotopia and polymicrogyria are a rare group of congenital malformations of the brain Septo-optic dysplasia-schizencephaly complex is frequently associated with endocrinolo gic, ophthalmologic, and neurologic symptoms and signs. We recently experienced a case of septo-optic dysplasia-schizencephaly, who showed severe visual impairment associated nystagmus and bilateral optic nerve hypoplasia agenesis of septum pellucidum with schizencephaly and hypsarrythmia. Because some forms of migrational disorders and septo-optic dysplasia can be inherited, parental counseling is essential for the accurate diagnosis.
Brain ; Counseling ; Diagnosis ; Humans ; Lissencephaly ; Malformations of Cortical Development ; Neurologic Manifestations ; Optic Nerve ; Parents ; Seizures ; Septo-Optic Dysplasia ; Septum Pellucidum ; Vision Disorders

We report a case of polycythemia vera combined with coagulation disorder. The patient was 54 years old man who complained of continuous bleeding after incision of skin abscess 20days ago. Laboratory tests were revealed prolonged aPTT and slightly prolonged PT. Coagulation factor, I, VIII, IX, XI and fibrinogen decreased, however FDP did not increased. It appears that patient with polycythemia vera have chronic activation of coagulation system, probably initiated by activation of factor XII. Platelet aggregation test to ADP, collagen, epinephrine was also revealed poor response.
Abscess ; Adenosine Diphosphate ; Blood Coagulation Factors ; Collagen ; Epinephrine ; Factor XII ; Fibrinogen ; Hemorrhage ; Humans ; Platelet Aggregation ; Polycythemia Vera* ; Polycythemia* ; Skin

Miller Fisher syndrome is characterized by acute external ophthalmoplegia, ataxia and areflexia in the abscence of significant motor or sensory deficit in the limbs and usually results in a complete recovery. Most cases have anteceding events like upper respiratory infection or other viral infections. Diagnosis of Miller fisher syndrome can be made with compatible clinical history taking, cardinal symptoms and normal findings of CT or MRI. The prognosis of Miller Fisher syndrome is favorable contrary to other malignant tumors or Guillain-Barre syndrome which sometimes cause a respiratory paralysis. The locations of its anatomic lesion and pathogenesis are nor yet discovered. From 1991 to 1995, we have experienced 11 cases of Miller Fisher syndrome. Thereby we have analyzed anteceding events, cardinal symptoms along with other associated symptoms, electrophysiological studies, cerebrospinal fluid test and its treatment and prognosis. The purpose of this article is that a better understanding of Miller Fisher syndrome can lead us to differenciate with other disorders causing external ophthalmoplegia.
Ataxia ; Cerebrospinal Fluid ; Diagnosis ; Extremities ; Guillain-Barre Syndrome ; Magnetic Resonance Imaging ; Miller Fisher Syndrome* ; Ophthalmoplegia ; Prognosis ; Respiratory Paralysis