1.Pallor.
Hyo Seop AHN ; Hyoung Soo CHOI
Journal of the Korean Medical Association 1998;41(12):1272-1276
No abstract available.
Pallor*
2.A Case of Bilateral Wilms' Tumor.
Hyun Jun CHO ; In Sang JEON ; Hyo Seop AHN ; Hwang CHOI
Journal of the Korean Pediatric Society 1990;33(1):117-123
No abstract available.
Wilms Tumor*
3.A case of squamous carcinoma in situ associated with condyloma acuminatum of the anus: report of a case.
Hyo Seop YOON ; Byoung Yoon RYU ; Young Joo LEE ; Hong Ki KIM ; Chang Sig CHOI
Journal of the Korean Surgical Society 1993;45(4):597-602
No abstract available.
Anal Canal*
;
Carcinoma, Squamous Cell*
4.A Case Report Kostmann Syndrome.
Han Wook YOO ; Son Moon SHIN ; Hyo Seop AHN ; Yong CHOI ; Chang Yee HONG
Journal of the Korean Pediatric Society 1983;26(3):284-288
No abstract available.
5.Effect of Preoperative Chemotherapy.
Jae Kyung LEE ; Hyeong Soo CHOI ; Ki Woong SUNG ; Hee Young SHIN ; Hyo Seop AHN
Korean Journal of Pediatric Hematology-Oncology 1997;4(1):105-117
BACKGROUND: The survival rate of children with neuroblastoma has been improved over 20 years, excluding the metastatic disease, in which it does not exceed 20% so far. New treatment modalities have been developed to improve the outcome in metastatic disease. Preoperative chemotherapy reduce the size, the vascularity and the adhesiveness, so increase the resectability of the primary tumor. This retrospective clinical study was designed to review the survival rate in neuroblastoma and to analyze the effect of preoperative chemotherapy in the view point of neoadjuvant therapy on long-term survival in advanced disease. METHODS: One hundred and thirty-four cases were reviewed from 135 patients with neuroblastoma registered at the Department of Pediatrics in Seoul National University Children's Hospital from January, 1985 till December, 1995. The survival rate was reviewed according to the stage. The age, sex of the patients, the stage, anatomical site of the tumor, the level of serum ferritin and neuron-specific enolase were analyzed for the risk factors on survival. RESULTS: Ranges of age at diagnosis were from 1 month to 166 months with the median of 39 months. Five year survival rates and five year disease-free survival rates were 100%, 100% in stage 1(n=5), 90.9%, 90.9% in stage 2(n=13), 43.4%, 40.6% in stage 3(n=19), 27.1%, 19.8% in stage 4(n=95) and 100%, 100% in stage 4S(n=2), respectively. In stage 3, five year survival rate was 52.5% in group receiving neoadjuvant chemotherapy, 28.6% in control group(P=0.02). Five year disease-free survival rate was also noted as 48.6%, 28.6% in each group(P=0.02). In stage 4, five year and ten year survival rates were 27.6%, 23.6% in group receiving neoadjuvant chemotherapy, 26.9%, 0% in control group(P=0.02). Five year and ten year disease-free survival rates were 14.3%, 14.3% in group receiving neoadjuvant chemotherapy, 20%, 0% in control group (P=0.11). In univariate analysis, the age, the stage, and the site of primary tumor appeared to affect the long-term survival. CONCLUSION: Neoadjuvant chemotherapy and delayed primary surgery contribute for advance in survival in advanced neuroblastoma via increasing the resectability of the primary tumor.
Adhesiveness
;
Child
;
Diagnosis
;
Disease-Free Survival
;
Drug Therapy*
;
Ferritins
;
Humans
;
Neoadjuvant Therapy
;
Neuroblastoma
;
Pediatrics
;
Phosphopyruvate Hydratase
;
Retrospective Studies
;
Risk Factors
;
Seoul
;
Survival Rate
6.Two Cases of Hemolytic Disease of Newborn due to Anti-E.
Se Won PARK ; Young Sun KIM ; Jung Hwan CHOI ; Hyo Seop AHN ; Chong Ku YUN
Journal of the Korean Pediatric Society 1986;29(2):85-90
No abstract available.
Erythroblastosis, Fetal*
;
Infant, Newborn
8.Three Cases of Congenital Hypoplastic Anemia.
Heui Jeong KWON ; Myung Hyun LEE ; Jung Hwan CHOI ; Hyo Seop AHN ; Chang Yee HONG
Journal of the Korean Pediatric Society 1985;28(8):829-835
No abstract available.
Anemia, Hypoplastic, Congenital*
9.A case of Dandy-Walker syndrome.
Kyung Hee KIM ; Jong Leam CHOI ; Hyo Sook HONG ; Wan Seop KIM
Journal of the Korean Pediatric Society 1989;32(11):1586-1591
No abstract available.
Dandy-Walker Syndrome*
10.A clinical analysis and evaluation of long term effect of surgical treatment of peptic ulcer.
Hyo Seop YOON ; Hae Wan LEE ; Byoung Yoon RYU ; Hong Ki KIM ; Chang Sig CHOI
Journal of the Korean Surgical Society 1993;45(2):182-192
No abstract available.
Peptic Ulcer*