1.A clinical analysis of breast cancer.
Seong Hwan HWANG ; Jin Yong LEE ; Sang Hyo KIM
Journal of the Korean Surgical Society 1992;42(6):776-786
No abstract available.
Breast Neoplasms*
;
Breast*
2.Management of retroperitoneal hematoma.
Young Seok JEONG ; Jin Yong LEE ; Sang Hyo KIM
Journal of the Korean Surgical Society 1991;40(3):341-353
No abstract available.
Hematoma*
3.A Clinical Analysis of 33 Cases of Congenital Samll Intestinal Atresia.
Hyo Sin KIM ; He Jin IM ; Ock Seung JEONG ; Son Sang SEO ; Jung Woo YANG
Journal of the Korean Pediatric Society 1987;30(3):291-296
No abstract available.
Intestinal Atresia*
4.Whole Cow's milk Related iron Deficiency Anemia in Early Childhood.
In Sang JEON ; Heon Seok HAN ; Hyo Seop AHN ; Jin Q KIM
Journal of the Korean Pediatric Society 1990;33(10):1374-1379
No abstract available.
Anemia, Iron-Deficiency*
;
Iron*
;
Milk*
5.Effects of plateletpheresis on platelet aggregation in healthy donors.
Heon Chan PARK ; Hyo Jin CHUN ; Dong Seok JEON ; Jae Ryong KIM ; Sang Kyun PARK
Korean Journal of Blood Transfusion 1993;4(1):55-60
No abstract available.
Blood Platelets*
;
Humans
;
Platelet Aggregation*
;
Plateletpheresis*
;
Tissue Donors*
6.Pulsating Magnetic Field Effects on in vitro Culture of Human Osteogenic Sarcoma Cell Lines.
Hyo Sook SHIN ; Jin Young LEE ; Suk Keun LEE ; Sang Chul PARK ; Je G CHI
Korean Journal of Pathology 2000;34(3):169-180
In order to elucidate the biological effects of pulsating magnetic field in in vitro culture system we designed a pulsating magnetic apparatus using 120 Hertz, 24 Volt direct current. It can generate 63~225 Gauss in the experimental area of 90 mm petri dish, and has little thermal effect on the culture media in 37.5oC, 5% CO2. Human osteogenic sarcoma (HOS) cells were cultured in the pulsating magnetic field and the nuclear changes of cultured cells were observed routinely by hematoxylin staining, and apoptotic change was detected by ApopTag staining using both peroxidase and fluorescein labelings. Compared to the control group which formed well organized whorling pattern of HOS cell line in 3 days culture, the HOS cells cultured in the pulsating magnetic field for 12 hours or 24 hours grew irregularly and showed increased number of apoptotic cells. When the flow of pulsating magnetic field was interrupted by insertion of strong permanent magnetic bar (1000 Gauss, 5530 mm) beneath the petri dish during in vitro culture, the area of sparse pulsating magnetic field showed active proliferation and aggregation of HOS cells even in 24 hour exposure group. These data suggest that the pulsating magnetic field may play a role in inducing growth retardation and apoptosis of HOS cells. Furthermore, the hazardous effects of pulsating magnetic field can be lessened or nullified by the interruption of pulsating magnetic field with a strong permanent magnetic bar.
Apoptosis
;
Cell Line*
;
Cells, Cultured
;
Culture Media
;
Fluorescein
;
Hematoxylin
;
Humans*
;
Magnetic Fields*
;
Osteosarcoma*
;
Peroxidase
7.Defecographic Findings of Young Asymptomatic Volunteers.
Hyo Jin PARK ; Hoon JI ; Ki Whang KIM ; Sang Wook YOON
Journal of the Korean Radiological Society 1994;31(4):719-725
PURPOSE: Defecography is a technique of examining the rectum and anal canal by using fluoroscopy during defecation. This study was done to determine the range of normal findings of defecography in young asymptomatic Korean volunteers. MATERIALS AND METHODS: Twenty-nine asymptomatic young volunteers underwent defecography. Anorectal angle, perineal descent, length and width of anal, rectocele, rectal intussusception and incontience were evaluated. RESULTS: The range of anorectal angle was 82 degrees-149 degrees in resting state, compared to the 63 degrees -116 degrees in squeezing state, and 95 degrees -116 degrees in straining state respectively. The pelvic floor in straining state descended on average of 1.62cm from the inferior margin of ischial tuberosity that its broad range of position from --5.2cm to 0.8 cm implies a wide variation of anorectal angle and periheal descent. Mild degree of rectocele with less than 2cm of depth was found in 12 out of 29 cases. Rectal intussusception was noted in six and rectal incontinence was seen in one case. Formation of rectocele and intussusception during defecation was common in asymptomatic young volunteers. CONCLUSION: The wide range of defecographic measurements warrants the necessity of other complementary studies on anorectal function to improve the diagnostic accuracy. The interpretation of defecographic measurement should therefore be made with caution and should not be used as the sole criteria for seliction of treatment modality.
Anal Canal
;
Defecation
;
Defecography
;
Fluoroscopy
;
Intussusception
;
Pelvic Floor
;
Rectocele
;
Rectum
;
Volunteers*
8.Influence of late removal after treatment on the removal torque of microimplants
The Korean Journal of Orthodontics 2022;52(3):201-209
Objective:
To compare the removal torque of microimplants upon post-use removal and post-retention removal and to assess the influencing factors.
Methods:
The sample group included 241 patients (age, 30.25 ± 12.2 years) with 568 microimplants. They were divided into the post-use (microimplants removed immediately after use or treatment) and post-retention (microimplants removed during the retention period) removal groups. The removal torque in both groups was assessed according to sex, age, placement site and method, and microimplant size. Pearson correlation and multiple linear regression analyses were performed for evaluating variables influencing the removal torque.
Results:
The mean period of total in-bone stay of microimplants in the postretention removal group (1,237 days) was approximately two times longer than that in the post-use removal group (656.28 days). The removal torques in the post-retention removal group (range, 4–5 N cm) were also higher than those in the post-use removal group. The mandible and pre-drilling groups demonstrated higher placement and removal torques than did the maxilla and no-drilling groups, respectively. In the no-drilling post-use removal group, the placement torque and microimplant length positively correlated with the removal torque. In the post-retention removal group, unloading in-bone stay period and microimplant diameter positively correlated with the removal torque in the no-drilling and pre-drilling methods, respectively.
Conclusions
The removal torques differed according to the orthodontic loading and removal time of microimplants. With prolonged retention of microimplants inserted using the no-drilling method, the removal torque was clinically acceptable and positively correlated with the unloading in-bone stay period.
10.Glomerular filtration rate as a kidney outcome of diabetic kidney disease: a focus on new antidiabetic drugs
Hyo Jin KIM ; Sang Soo KIM ; Sang Heon SONG
The Korean Journal of Internal Medicine 2022;37(3):502-519
Diabetes has reached epidemic proportions, both in Korea and worldwide and is associated with an increased risk of chronic kidney disease and kidney failure (KF). The natural course of kidney function among people with diabetes (especially type 2 diabetes) may be complex in real-world situations. Strong evidence from observational data and clinical trials has demonstrated a consistent association between decreased estimated glomerular filtration rate (eGFR) and subsequent development of hard renal endpoints (such as KF or renal death). The disadvantage of hard renal endpoints is that they require a long follow-up duration. In addition, there are many patients with diabetes whose renal function declines without the appearance of albuminuria, measurement of the eGFR is emphasized. Many studies have used GFR-related parameters, such as its change, decline, or slope, as clinical endpoints for kidney disease progression. In this respect, understanding the trends in GFR changes could be crucial for developing clinical management strategies for the prevention of diabetic complications. This review focuses on the clinical implication of the eGFR-related parameters that have been used so far in diabetic kidney disease. We also discuss the use of recently developed new antidiabetic drugs for kidney protection, with a focus on the GFR as clinical endpoints.