1.In vitro platelet assessment of the stored CPDA-1 platelet concentrates.
Kan Hee HAN ; Jang Soo SUN ; Nam Kyung KIM ; Jay Sik KIM ; Dal Hyo SONG
Korean Journal of Blood Transfusion 1992;3(2):143-150
No abstract available.
Blood Platelets*
2.Identification of Br platelet antigens using modified mixed passive hemagglutination.
Nam Kyung KIM ; Jang Soo SUH ; Jay Sik KIM ; Dal Hyo SONG ; Young Chul OH ; Ki Hong KIM
Korean Journal of Blood Transfusion 1992;3(2):151-157
No abstract available.
Blood Platelets*
;
Hemagglutination*
3.A Study of Voiding Patterns and Pressure Ulcer for the Residents of Long Term Care Facilities.
Hyo Jeong SONG ; Su Mi KIM ; Nam Cho KIM
Journal of the Korean Continence Society 2003;7(2):91-97
PURPOSE: This study was designed to provide the basic data for the development of the urinary incontinence nursing management program by identifying voiding patterns and pressure ulcer prevalence of residents in long term care facilities. MATERIALS AND METHODS: The study was performed from January to February, 2003. The subjects consisted of 92 residents in long term care facilities around S city. Researcher visited the facilities and assessed their voiding patterns, voiding management, and skin. To investigate the voiding patterns of the residents, care givers in the facilities were educated how to fill up voiding diaries and the diaries were made for two days. The data were analyzed by t-test and x2-test with using SAS program. RESULTS: The mean score for the activities of daily living of the subjects was 17.7+/-10.3 indicating medium. Mean score for mental status was 2.5+/-3.5 indicating very low. Among the subjects, self-voiding group was 40.8%, the group with self-voiding at daytime and diapers at night 10.9%, the group managed with diapers all the time 41.1%. In UI status of self-voiding group, urge urinary incontinence 22.8%, mixed urinary incontinence 13.6%, stress urinary incontinence 6.8%, and 56.8% had no urinary incontinence. About 9.8% of the subjects suffered from pressure ulcers and 15% of the group managed with diapers all the time had skin problems at perineal area. Between the group with pressure ulcer and the group without pressure ulcer, there were significant differences by length of residence, activities of daily living, mental status, and Braden scale. CONCLUSION: The above findings indicated that the care programs for the group managed with diaper change and the group with skin problems were required to improve, and the voiding management focusing on rehabilitation rather than simple diaper change should be encouraged.
Activities of Daily Living
;
Caregivers
;
Humans
;
Long-Term Care*
;
Nursing
;
Pressure Ulcer*
;
Prevalence
;
Rehabilitation
;
Skin
;
Urinary Incontinence
4.Low levels of 25-hydroxyvitamin D in children and adolescents with type 1 diabetes mellitus: a single center experience.
Ki Nam BAE ; Hyo Kyoung NAM ; Young Jun RHIE ; Dae Jin SONG ; Kee Hyoung LEE
Annals of Pediatric Endocrinology & Metabolism 2018;23(1):21-27
PURPOSE: Low vitamin D level is common in adults with diabetes mellitus (DM). We assessed vitamin D level and its associated factors in Korean youth with type 1 DM. METHODS: Type 1 DM cases (n=85) and healthy controls (n=518) aged < 20 years were included and grouped into 3 categories according to vitamin D level: deficiency ( < 20 ng/mL), insufficiency (20–30 ng/mL), or sufficiency (≥30 ng/mL). RESULTS: The mean serum vitamin D level was significantly lower (21.6±8.5 ng/mL vs. 28.0±12.0 ng/mL, P < 0.001) and vitamin D deficiency prevalence was significantly higher (48% vs. 26%, P < 0.001) in type 1 DM cases than in healthy controls. Logistic regression analysis revealed that type 1 DM cases were more likely to have vitamin D deficiency (P=0.004), independent of sex, age, and body mass index. Type 1 DM cases with vitamin D deficiency/insufficiency were mainly diagnosed in winter (November to April) (P=0.005), and the duration of diabetes was longer than in those with vitamin D sufficiency (P=0.046). However, season of diagnosis, duration of diabetes, prescribed daily insulin dose, and glycosylated hemoglobin and C-peptide levels were not associated with 25-hydroxyvitamin D (25(OH)D) level in type 1 DM cases after adjustment for other factors. CONCLUSIONS: We recommend assessment of serum 25(OH)D level in type 1 DM cases and to treatment if findings indicate insufficiency. Further studies investigating the mechanisms underlying vitamin D deficiency in youth with type 1 DM are needed.
Adolescent*
;
Adult
;
Body Mass Index
;
C-Peptide
;
Case-Control Studies
;
Child*
;
Diabetes Mellitus
;
Diabetes Mellitus, Type 1*
;
Diagnosis
;
Hemoglobin A, Glycosylated
;
Humans
;
Insulin
;
Logistic Models
;
Prevalence
;
Seasons
;
Vitamin D
;
Vitamin D Deficiency
5.Hepatoid thymic carcinoma: a case report of a rare subtype of thymic carcinoma
Ji-Seon JEONG ; Hyo Jeong KANG ; Uiree JO ; Min Jeong SONG ; Soon Yeol NAM ; Joon Seon SONG
Journal of Pathology and Translational Medicine 2021;55(3):230-234
Hepatoid thymic carcinoma is an extremely rare subtype of primary thymus tumor resembling “pure” hepatoid adenocarcinomas with hepatocyte paraffin 1 (Hep-Par-1) expression. A 53-year-old man presented with voice change and a neck mass. Multiple masses involving the thyroid, cervical and mediastinal lymph nodes, and lung were detected on computed tomography. Papillary thyroid carcinoma was confirmed by biopsy, and the patient underwent neoadjuvant chemoradiation therapy. However, the anterior mediastinal mass was enlarged after the treatment whereas the multiple masses in the thyroid and neck decreased in size. Microscopically, polygonal tumor cells formed solid sheets or trabeculae resembling hepatocytes and infiltrated remnant thymus. The tumor cells showed immunopositivity for cytokeratin 7, cytokeratin 19, and Hep-Par-1 and negativity for α-fetoprotein. Possibilities of germ cell tumor, squamous cell carcinoma, and metastasis of thyroid papillary carcinoma were excluded by immunohistochemistry. This report on the new subtype of thymic carcinoma is the third in English literature thus far.
6.Hepatoid thymic carcinoma: a case report of a rare subtype of thymic carcinoma
Ji-Seon JEONG ; Hyo Jeong KANG ; Uiree JO ; Min Jeong SONG ; Soon Yeol NAM ; Joon Seon SONG
Journal of Pathology and Translational Medicine 2021;55(3):230-234
Hepatoid thymic carcinoma is an extremely rare subtype of primary thymus tumor resembling “pure” hepatoid adenocarcinomas with hepatocyte paraffin 1 (Hep-Par-1) expression. A 53-year-old man presented with voice change and a neck mass. Multiple masses involving the thyroid, cervical and mediastinal lymph nodes, and lung were detected on computed tomography. Papillary thyroid carcinoma was confirmed by biopsy, and the patient underwent neoadjuvant chemoradiation therapy. However, the anterior mediastinal mass was enlarged after the treatment whereas the multiple masses in the thyroid and neck decreased in size. Microscopically, polygonal tumor cells formed solid sheets or trabeculae resembling hepatocytes and infiltrated remnant thymus. The tumor cells showed immunopositivity for cytokeratin 7, cytokeratin 19, and Hep-Par-1 and negativity for α-fetoprotein. Possibilities of germ cell tumor, squamous cell carcinoma, and metastasis of thyroid papillary carcinoma were excluded by immunohistochemistry. This report on the new subtype of thymic carcinoma is the third in English literature thus far.
7.A Study of Overactive Bladder for the Women Aged over 30 years.
Hyo Jeong SONG ; Myung Ja KIM ; Nam Young YANG ; Mi Sook LEE ; In Ok LEE ; Ju Sun NAM ; Hae Hyang SONG ; Eun Joo LEE ; Joon Chul KIM ; Ji Youl LEE ; Donghwan LEE
Journal of the Korean Continence Society 2002;6(2):44-53
PURPOSE: This study was designed to provide the basic data for the development of the management program for overactive bladder by ascertaining its prevalence among Korean women aged over 30 years, and the factors related to its occurrence. MATERIALS AND METHODS: The study was performed by using self-questionnaires through the community-based cross sectional study from May to July, 2000. The subjects consisted of 2869 women, aged over 30 up to 89 years, among those who understood and responded to the questionnaires, and was residing in Seoul, Kyongki Kangwon, Chungchong, YongNam, HoNam, Cheju proinces. They also did not have known neurological problem and diabetes mellitus. The data were analyzed by Student t-test, chi2-test, and multiple logistic regression with using SAS program. RESULTS: The results were as follows ; 1. They all experienced at least one of frequency, urgency, nocturia, urge incontinence for the past one year and 52.3% of the subjects had experienced symptom at least once in 5 voidings. The highest prevalence of overactive bladder was 86.2% in the category for 70 to 89 years, 74.3% for the sixties, 45.3% for the forties, 42.5% for the thirties. In the symptoms of 1499 women among subject, 19.4% of them had nocturia, 18.2% frequency, 10.5% urgency, 9.6% urge incontinence, 9.5% frequency and urgency, 5.9% frequency and nocturia. 2. The age(OR = 1.041, 95% Cl = 1.027, 1.055) and the menopause(OR = 0.696, 95% Cl = 0.527, 0.919) were related to overactive bladder occurrence. CONCLUSIONS: The above findings indicated that about the half of the women aged over 30 years had symptoms for overactive bladder, and the prevalence was higher in old women and the women with menopause. So, the prevention and management programs for overactive bladder are required to be developed, and the primary screening programs based on community shall be developed.
Diabetes Mellitus
;
Female
;
Gangwon-do
;
Gyeonggi-do
;
Humans
;
Jeju-do
;
Logistic Models
;
Mass Screening
;
Menopause
;
Nocturia
;
Prevalence
;
Surveys and Questionnaires
;
Seoul
;
Urinary Bladder, Overactive*
;
Urinary Incontinence, Urge
8.The Prediction of Changes in Mean Corneal Refractive Power by Pterygium Size after Pterygium Surgery.
Ki Tae NAM ; Young Sub EOM ; Jay Won RHIM ; Su Yeon KANG ; Hyo Myung KIM ; Jong Suk SONG
Journal of the Korean Ophthalmological Society 2014;55(11):1613-1617
PURPOSE: To assess the changes in mean corneal refractive power (DeltaK) following pterygium surgery and to predict DeltaK in cases of combined cataract and pterygium surgery. METHODS: Thirty-seven eyes of unilateral pterygium patients who underwent pterygium surgery were analyzed retrospectively with at least more than 1 month of follow-up. Preoperative and postoperative 1 month corneal refractive power was measured using auto-keratometer (RK-F1, Canon, Tokyo, Japan). Pterygium horizontal extension, width, and area were measured and correlation with DeltaK before and after surgery analyzed. We also compared DeltaK of the contralateral normal eye. RESULTS: The mean corneal refractive (Km) power measured before and 1 month after surgery was 43.30 +/- 1.66 D and 44.07 +/- 1.42 D, respectively. The Km significantly increased at 4 weeks after surgery (p < 0.001). However, postoperative Km was not significantly different when compared with the contralateral normal eye (43.86 +/- 1.34 D; p = 0.59). All parameters of pterygium size including horizontal extension, width, and area were positively correlated with the mean DeltaK. Among parameters, horizontal extension was best correlated with mean DeltaK (p < 0.001). The mean DeltaK with horizontal extension was predicted using linear regression (2.5 mm to 1 D, 4.0 mm to 1.8 D). CONCLUSIONS: We recommend contralateral corneal refractive power or prediction of corneal refractive power using linear regression with pterygium horizontal extension for determining intraocular lens power in cases of combined cataract and pterygium surgery.
Cataract
;
Follow-Up Studies
;
Humans
;
Lenses, Intraocular
;
Linear Models
;
Pterygium*
;
Retrospective Studies
9.An 18-year-old patient with Prader-Willi syndrome: a case report on dental management under sedation and general anesthesia.
Ki Un SONG ; Ok Hyung NAM ; Mi Sun KIM ; Sung Chul CHOI ; Hyo Seol LEE
Journal of Dental Anesthesia and Pain Medicine 2015;15(4):251-255
Prader-Willi syndrome (PWS) is a rare genetic disorder reported rarely in dentistry. Dental practitioners should know the features of PWS because affected patients have a variety of dental symptoms. The current report describes a case of PWS. An 18-year-old male patient presented with traumatic injuries. Initial emergency treatments were performed under sedation, and further treatments were conducted under general anesthesia. After adequate healing, periodic follow-up and dietary management according to the patient's age and nutritional phase were recommended. Dental management of PWS patients consists of active preventive measures in addition to dietary consultation according to age and nutritional phase.
Adolescent*
;
Anesthesia, General*
;
Conscious Sedation
;
Dentistry
;
Emergency Treatment
;
Follow-Up Studies
;
Humans
;
Hyperphagia
;
Male
;
Practice Management, Dental
;
Prader-Willi Syndrome*
10.Expression of Beta-catenin and E-cadherin in Early Gastric Cancer: Correlation with Clinicopathologic Parameters.
Byung Joo SONG ; Young Jin PARK ; Han Seong KIM ; Chul Nam KIM ; Seok Hyo CHANG
The Korean Journal of Gastroenterology 2004;43(2):82-89
BACKGROUND/AIMS: Beta-catenin is known to perform two unrelated functions in cadherin-mediated cell to cell adhesion system and Wnt pathway. Recent studies reported cytoplasmic and nuclear accumulation of beta-catenin by Wnt signaling and/or abnormal Wnt pathway in cancer cells. Nuclear accumulations of beta-catenin have a crucial role in early tumor growth and initiation of invasive growth in gastric cancer. METHODS: We carried out clinicopathological and immunohistochemical studies for beta-catenin, p53, E-cadherin, and Ki-67 in the specimens from 60 early gastric cancer patients who were treated with curative resections. RESULTS: Twenty-five (41.7%) and twenty-nine (48.3%) cases showed a nuclear and cytoplasmic expression of beta-catenin, respectively. There were significant correlations between nuclear expression of beta-catenin and well-differentiated and intestinal type of early gastric carcinoma. Cytoplasmic expression of beta-catenin had significant correlations with nuclear expression of beta-catenin (p=0.011). CONCLUSIONS: Nuclear expression of beta-catenin is significantly influenced by histological grade, Lauren classification and cytoplasmic expression of beta-catenin in early gastric cancer. These findings suggest that nuclear expression of beta-catenin is correlated with early tumorigenesis and initiation of invasive growth in gastric cancer.
Adult
;
Aged
;
Aged, 80 and over
;
Cadherins/*metabolism
;
Carcinoma/*metabolism/pathology
;
Cell Nucleus/metabolism
;
Cytoplasm/metabolism
;
Cytoskeletal Proteins/*metabolism
;
English Abstract
;
Female
;
Humans
;
Ki-67 Antigen/analysis
;
Male
;
Middle Aged
;
Protein p53/metabolism
;
Stomach Neoplasms/*metabolism/pathology
;
Trans-Activators/*metabolism