No abstract available.
Transposases*

Congenital Abnormalities ; Female ; Humans ; Jaw ; Jeollabuk-do ; Male ; Orthognathic Surgery ; Osteotomy ; Osteotomy, Sagittal Split Ramus ; Rehabilitation ; Surgery, Oral

BACKGROUND: In retrospective studies relating body weight to disease, the source of information on the Past body weight and height is often based on recall. Several studies examined the accuracy of recalled body weight and height, and factors that might affect the accuracy of recall but data on the accuracy of the recalled weight and height are scare. This study examined the eccuracy of recalled body weight and height, over a 5year period. METHODS: Participants was two hundred and two men and women visiting Health Promotion Center of medical colleage hospital, from 1th Jan. to 30th Jun.1996. We compared of measured weight and height with recalled weight and height 6year later and examined of the influence of sex, occupation, education, chronic disease on recall. RESULTS: When we defined recall error as measured body weight and height minus recalled body weight and height, the mean of weight errors were 0.02 +/-3.22 kg, and the measured body weight was significantly correlated with recalled body weight (r = 0.96). The mean of height errors were -0.80 1.95 cm, the correlation was 0.97. Weight errors were negatively correlated to weight gain over 5year period (r= -0.49). The accuracy of recall was not influenced by sex, education, occupation, chronic disease. CONCLUSION: Middle aged men and women recalled their previous 6year weight and height well in this study. The recalled past body weight and height are feasible information in retrospective study relating body weight to disease.
Body Weight* ; Chronic Disease ; Education ; Female ; Health Promotion ; Humans ; Male ; Middle Aged* ; Occupations ; Retrospective Studies ; Weight Gain

Objectives: This study aimed to examine oral health literacy (OHL) in mothers and the factors that influence it. Methods: A total of 431 mothers of preschool children were chosen as study participants using the convenience sampling method. A self-administered questionnaire was used in this study. The survey contents included the socioeconomic characteristics of the participants as well as their level of oral health literacy. Results: In total, 44.8 percent of the participants had a low level of verbal oral health literacy (0-6 grade), and 16.9 percent had a low functional oral health literacy (≤6). Educational level and family income were significantly associated with the participants’ oral health literacy (Pearson correlation). Verbal oral health literacy of the participants was related to their family’s income, whereas their functional oral health literacy was related to their educational level. Conclusions Many of the participants had a low level of oral health literacy. For mothers, to improve their oral health literacy, an oral health literacy program must be in place. Oral health literacy programs should be targeted toward mothers with low socioeconomic status.

Objectives: This study aimed to examine oral health literacy (OHL) in mothers and the factors that influence it. Methods: A total of 431 mothers of preschool children were chosen as study participants using the convenience sampling method. A self-administered questionnaire was used in this study. The survey contents included the socioeconomic characteristics of the participants as well as their level of oral health literacy. Results: In total, 44.8 percent of the participants had a low level of verbal oral health literacy (0-6 grade), and 16.9 percent had a low functional oral health literacy (≤6). Educational level and family income were significantly associated with the participants’ oral health literacy (Pearson correlation). Verbal oral health literacy of the participants was related to their family’s income, whereas their functional oral health literacy was related to their educational level. Conclusions Many of the participants had a low level of oral health literacy. For mothers, to improve their oral health literacy, an oral health literacy program must be in place. Oral health literacy programs should be targeted toward mothers with low socioeconomic status.

Purpose: Given the long history of investigation into cancer and its relevance to the lymph node (LN), it would be meaningful to plot the trends of research on cancer-related LN. Methods: Queries such as “cancer,” “lymph node,” and “cancer and lymph node” were submitted to PubMed to collect articles on cancer and LN published between 1945 and 2017. The collected articles were then extracted by an automatic web crawler and examined through informetrics and linguistic analysis. Results: The number of articles related to cancer was 2,795,476 and 127,897 articles (4.6%) were found to be relevant to LN. With regard to cancer types, breast cancer was the most studied (37%), followed by gastric cancer (17%). With regard to the subjects in which the surgeon is interested, LN metastasis (57%) was found to be the topic most discussed, followed by LN dissection (22%) and sentinel LN (17%). Publications on LN metastasis gradually increased over time from 1988 to 2017 although those on sentinel LN and LN dissection have stagnated since the early 2000s. Conclusion Although research on cancer was abundant, only a small portion was dedicated to investigating its relevance to LN. Western countries had led the research on cancer-related LN, but Asian countries began to participate as major players, expanding their contributions. While LN metastasis, one of the major cancer-related LN topics, showed a steady increase, those involved in oncologic surgery such as LN dissection and sentinel LN did not.

Despite the increasing use of alternative analgesic agents, salicylate overdose remains a not-uncommon problem. Severe poisoning is life threatening, so prompt treatment and supportive measures are required to reduce mortality. Generally, salicylate intoxication results in the development of high-anion-gap metabolic acidosis. However, outside of Korea, normal-anion-gap or negative-anion-gap metabolic acidosis with hyperchloremia is rarely reported. We report herein the case of an 83-year-old female patient with chronic aspirin intake who presented with hyperchloremia and a negative anion gap. The patient's symptoms improved with conservative treatment and hemodialysis; notably, her chloride levels decreased as her blood salicylate concentrations decreased. Salicylate may cause hyperchloremia, demonstrating the importance of careful documentation of patient medication histories.
Acid-Base Equilibrium ; Acidosis ; Aged, 80 and over ; Analgesics ; Aspirin ; Female ; Humans ; Korea ; Mortality ; Poisoning ; Renal Dialysis

Previously, we constructed a humanized antibody (HuS10) that binds to the common a antigenic determinant on the S protein of HBV. In this study, we evaluated its HBV-neutralizing activity in chimpanzees. A study chimpanzee was intravenously administered with a single dose of HuS10, followed by intravenous challenge with the adr subtype of HBV, while a control chimpanzee was only challenged with the virus. The result showed that the control chimpanzee was infected by the virus, and thus serum HBV surface antigen (HBsAg) became positive from the 14th to 20th week and actively acquired serum anti-HBc and anti-HBs antibodies appeared from the 19th and 23rd week, respectively. However, in the case of the study chimpanzee, serum HBsAg became positive from the 34th to 37th week, while actively acquired serum anti-HBc and anti-HBs antibodies appeared from the 37th and 40th week, respectively, indicating that HuS10 neutralized the virus in vivo and thus delayed the HBV infection. This novel humanized antibody will be useful in the immunoprophylaxis of HBV infection.
Animals ; CHO Cells ; Cricetinae ; Cricetulus ; Hepatitis B/blood/immunology/virology ; Hepatitis B Antibodies/blood/*immunology ; Hepatitis B Surface Antigens/*immunology ; Hepatitis B virus/*immunology ; Neutralization Tests ; Pan troglodytes/blood/*immunology/*virology

OBJECTIVES: The purpose of this study was to assess the impact of oral health literacy on oral health-related quality of life (OHRQoL). METHODS: Self-administered questionnaires were handed out to 760 adults above the age of 18 selected through convenience sampling. Among them, those above 60 years of age were also interviewed face-to-face. The Rapid Estimate of Adult Literacy in Dentistry (REALD-99) and the Test of Functional Health Literacy in Dentistry (TOFHLiD) were used to measure verbal and functional oral health literacy respectively. OHRQoL was measured using the oral health impact profile-14 (OHIP-14), a simplified version of the oral health impact profile (OHIP). The sociodemographic characteristics (gender, age, marital status, education level, and income) were also recorded. Higher scores on oral health literacy represented higher levels of literacy, while higher OHIP-14 scores implied that the OHRQoL was lower. RESULTS: During analyses, the sample was stratified into the top and bottom 25% based on functional oral health literacy levels. OHRQoL had a statistically significant negative correlation with functional oral health literacy. The items on functional limitation, physical disability, social disability, and handicap specifically showed negative correlations. Multiple regression analysis was performed after including sociodemograhic variables also. Only functional and not verbal oral health literacy had a statistically significant influence on OHRQoL. The higher the functional oral health literacy level, the higher was the OHRQoL. CONCLUSIONS: Enhancement of functional oral health literacy level through oral health education is necessary to improve the OHRQoL.
Adult* ; Dentistry ; Education ; Hand ; Health Literacy ; Humans ; Marital Status ; Oral Health* ; Quality of Life* ; Surveys and Questionnaires

BACKGROUND/AIMS: Acute suppurative cholangitis (ASC), a severe form of acute cholangitis, is a life-threatening condition that must be treated with appropriate and timely management. The purpose of this study was to identify the factors that predispose patients to ASC. METHODS: We retrospectively investigated 181 patients (100 men, 81 women; age, 70.66+/-7.38 years, mean+/-SD) who were admitted to Wonkwang University Hospital between January 2005 and June 2007 for acute cholangitis with common bile duct (CBD) stones. All patients underwent endoscopic retrograde cholangiopancreatogram to remove the stones. Variables and factors that could be assessed upon admission were analyzed to identify the risk factors for the development of ASC. RESULTS: Of the 181 patients, 44 (24.3%) presented with ASC. On multivariate analysis, the followings were found to be independent risk factors for the development of ASC: impacted common bile duct stone (p=0.010), current smoker status (p=0.008), advanced age (>70 years; p=0.002), and gallstone (p=0.016). The most commonly isolated organisms in bile culture were Enterococcus species, Escherichia coli, and Klebsiella species. CONCLUSIONS: Impacted bile-duct stones, current smoking, advanced age, and gallstones were identified as independent risk factors for the development of ASC in patients with CBD stones. These results suggest that emergency biliary drainage is beneficial in patients with these risk factors.
Bile ; Cholangitis ; Common Bile Duct ; Drainage ; Emergencies ; Enterococcus ; Escherichia coli ; Gallstones ; Humans ; Klebsiella ; Male ; Multivariate Analysis ; Retrospective Studies ; Risk Factors ; Smoke ; Smoking