1.Study of cutaneous hydration effect according to the vehicles of moisturizers.
Kyeong Joon HYEON ; Hong Jig KIM ; Jong Il KIM
Korean Journal of Dermatology 1991;29(1):8-17
We investigated on how the nature of vehicles influenced on the efficacy of mo isturizer s, cutaneous hydrat,ion, physical property and roughness. Hydration was measured with corneometer, physical property with fermometer, and mughness with image analyser. Used vehicles were as follows : hydrous gel, vater in oil(W/0) emulsion, oil in water(0/W) emulsion. I.Jsed moisturizers were as follows . glycerine, polypeptide and sodium lactat,e, hyaluronic acid-triethanolamine, sodium lactate, pvopylene glycol, The results are summarized as follows : 1. The increment of the hydration effect according to vehicles was in this order. C/ W emulsion, W/0 emulsion, hydrous gel(After 2 hours). 2. The increment of extensibility as physical property was correlated to the in crcment, of hydration effcet(r=0.924). 3. It was shown that, the roughness was decreased after treatment of all mo isturizers except propylene glycol but, there was not significant st.atistically and alsa was no meaningful difference among the vehicles. 4. Among t,he moisturizers, glycerine was superior to other moisturizers on the hydration effect and extensihility. We conclude that 0/W emulsion was suitable vehicle on cutaneous hydration effect and hydration effect is proportion to the increment of flexibility.
Glycerol
;
Pliability
;
Propylene Glycol
;
Sodium
;
Sodium Lactate
3.Surgical-orthodontic treatment of impacted teeth displaced by unicystic ameloblastoma.
Hyeon Shik HWANG ; Hyeon Hye KIM ; Jong Chul KIM
Korean Journal of Orthodontics 1997;27(3):515-521
The purpose of this case report is to provide the information of the treatment of the impacted-displaced teeth associated with the disease in the jaw. A 10-year-old boy presented with a large radiolucent lesion accompanying the displacement of the second premolar and first molar in the left mandibular body area. The lesion was diagnosed as unicystic ameloblastoma. As a surgical procedure for the present case, marsupialization was executed. For the eruption of displaced impacted teeth, no orthodontic intervention was done for second premolar while a helical spring was used for the forced eruption of first molar. Good occlusion was established by simple orthodontic intervention.
Ameloblastoma*
;
Bicuspid
;
Child
;
Humans
;
Jaw
;
Male
;
Molar
;
Orthodontic Extrusion
;
Tooth
;
Tooth, Impacted*
4.Molecular Cloning and Nucleotide Sequence of the Gene Encoding Fusion(F) Protein of the Thermostable Newcastle Disease Virus Isolated from a Diseased Pheasant.
Kyung Soo CHANG ; Kui Hyun KIM ; Moo Hyung JUN ; Hee Jong SONG ; Jong Hyeon PARK
Journal of the Korean Society of Virology 1998;28(3):233-244
The gene encoding F protein of CBP-1 strain, a heat-stable Newcastle disease virus (NDV) isolated from the diseased pheasants in Korea, was characterized by reverse transcription-polymerase chain reaction (RT-PCR), nucleotide and amino acid sequences. Virus RNA was prepared from the chorioallatoic fluid infected with NDV CBP-1 virus and cDNA was amplified by RT-PCR, cloned and sequenced to analyze. The PCR was sensitive as to detect the virus titer above 25 hemagglutination unit. 1.7kb (1,707bp) size of the cDNA was amplified and cloned into BamHI site of pVL1393 Baculo transfer vector. The nucleotide sequences for F protein were determined by dye terminator cyclic sequencing using four pairs of primers, and 553 amino acid sequences were predicted. In comparison of the nucleotide sequence of F gene of CBP-1 with those of other NDV strains, the homology revealed 88.8%, 98.5% and 98.7% with Kyojungwon (KJW), Texas GB and Beaudette C strains, respectively. As the deduced 553 amino acid sequences of F protein of CBP-1 were compared with those of other NDV strains, the homology appeared 89.9%, 98.7% and 98.9% with KJW, Texas GB and Beaudette C strains, respectively. The putative protease cleavage site (112-116) was R-R-Q-K-R, indicating that CBP-1 strain is velogenic type. The amino acid sequences include 6 sites of N-asparagine-linked glycosylation and 13 cysteine residues. These data indicate that the genotype of CBP-1 strain is more closely associated with the strains of Texas GB and Beaudette C than KJW strain.
Amino Acid Sequence
;
Animals
;
Base Sequence*
;
Clone Cells
;
Cloning, Molecular*
;
Cysteine
;
DNA, Complementary
;
Genotype
;
Glycosylation
;
Hemagglutination
;
Korea
;
Newcastle disease virus*
;
Newcastle Disease*
;
Polymerase Chain Reaction
;
RNA
;
Texas
;
Viral Load
5.Utility of Multiplanar Reformation Images of Helical CT in the Evaluation of Pancreatic Diseases.
Jun Ho KIM ; Hyun Jong KIM ; Heoung Keun KANG ; Yun Hyeon KIM ; Jong Hoon YOON ; Hyeong Kil KIM
Journal of the Korean Radiological Society 1995;33(2):273-278
PURPOSE: The purpose of this study is to assess the clinical utility of multiplanar reformation images of helical CT in the evaluation of pancreatic diseases. MATERIALS AND METHODS: Helical CT scans of the pancreas were obtained in 30 patients with pancreatic diseases. Helical CT was performed with 5mm collimation at 5mm/sec table speed during rapid injection of intravenous contrast agent using power injector. After scanning, helical volume data were reconstructed at 2mm interval and then multiplanar reformation of the pancreas and adjacent structures was done. In both prospective reconstructed axial images and multiplanar reformation images, detection of pancreatic lesion, extent of lesion, and vascular and bile ductal changes were analyzed with a grading system of 1,2, 3. RESULTS: The mean grade of detection of pancreatic lesions was 2.37 in the prospective axial image and 2.83 in multiplanar reformation image, extent of diseases was 2.40 in prospective axial image and 2.97 in multiplanar reformation image, and vascular and bile ductal changes was 2.00 in the prospective axial image and 2.97 in multiplanar reformation image. All the differences were statistically significant (P<0.0001). CONCLUSION: Multiplanar reformation images of helical CT are useful in the evaluation of pancreatic diseases and especially in the demonstratibn of complex anatomic relationships between the pancreas and surrounding structures.
Bile Ducts
;
Humans
;
Pancreas
;
Pancreatic Diseases*
;
Prospective Studies
;
Tomography, Spiral Computed*
6.Labial salivary gland biopsy in Sjogren's syndrome.
Hye Ok KIM ; Hyeon Jo KIM ; Jong Il CHOI ; Kyung Rae KIM ; Hyung Seok LEE
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(1):136-142
No abstract available.
Biopsy*
;
Salivary Glands*
;
Sjogren's Syndrome*
7.Therapeutic Effect of Cyclosporine a on Severe Henoch-Scholein Purpura Nephritis.
Pyung Kil KIM ; Ji Hong KIM ; Hyun Jong CHIN ; Hyeon Joo JEONG
Journal of the Korean Society of Pediatric Nephrology 1998;2(2):110-117
The fine needle aspiration (FNA) cytologic findings in 16 cases of histologically confirmed thymoma are reported. The aspirates were obtained under fluoroscopic guidance. The cytologic diagnoses were inadequate sample in one case, thymoma in 12 (75%), small cell carcinoma or thymoma in 1, benign mesenchymal tumor in 1, and germ cell tumor in one. The cytologic features were detailed according to the constituent epithelial cell type, and to the ratio of epithelial cells and lymphocytes. Fifteen cases were classified into 4 small epithelial cell type, 6 intermediate epithelial cell type, 1 large epithelial cell type, 1 large pleomorphic epithelial cell type, and 3 spindle-shaped epithelial cell type. Cytologic differential diagnosis was discussed, and the important criteria for the cytologic diagnosis of thymoma were reviewed. This review leads us to think that nonoperative cytologic approaches in the diagnosis of the thymoma are possible, and that correct cytologic diagnosis of thymoma with FNAs can easily be made, if adequate samples are obtained. However, the invasiveness and histologic type could not be predicted by cytological features only. Knowing various cytologic and histologic features of thymoma will be helpful for the diagnosis of thymoma and the differential diagnosis of mediastinal tumors.
Diagnosis, Differential
8.Intravenous Magnetic Resonance Arthrography of the Knee.
Seung Hee LEE ; Young Uk LEE ; Jong Dae SUH ; Jung Hyeon KIM ; Dong Joo KIM
Journal of the Korean Radiological Society 1995;33(4):627-632
PURPOSE: Knee IVIR images were repeatedly obtained after intravenous administration of gadopentetate dimeglumine to evaluate the arthrographic effect and to determine the optimal scan timing and technique. MATERIALS AND METHODS: Sagittal Tl-weighted (650/15) sequences were repeated before and after intravenous gadolinium enhancement in 26 patients who were divided into exercise (14/26) and nonexercise (12/26) groups. Fourteen patients in exercise group were allowed to move the affected knee joint actively for 10 minutes immediately after the first post-enhancement scan and before repeating scans. The signal intensities in central and peripheral portions of the joint were measured and compared between these two groups. RESULTS: In all cases, enhancement of joint fluid began at peripheral portion and progressed toward central portion. The diffusion rate in exercise group was far faster than that in nonexercise group and homogeneous arthrographic image was revealed within 10 minutes after completion of joint movement. The arthrographic effect continued and the rate of signal decrease was quite slow. CONCLUSION: MR arthrographic image of knee joint can be obtained within 10 minutes after completion of a few minute exercise following intravenous injection of gadopentetate dimeglumine. Intravenous MR arthrography is expected to become an useful method as a convenient alternative to direct MR arthrography.
Administration, Intravenous
;
Arthrography*
;
Diffusion
;
Gadolinium
;
Gadolinium DTPA
;
Humans
;
Injections, Intravenous
;
Joints
;
Knee Joint
;
Knee*
9.Comparative study of triflusal and ticlopidine on anti-platelet aggregatory effect and side effects.
Hyeon Gak KIM ; Jong Sung KIM ; Myoung Chong LEE
Journal of the Korean Neurological Association 1998;16(1):21-27
BACKGROUND AND PURPOSE: Platelet aggregation plays an important role in thrombogenesis. Thus antiplatelet agents, such as aspirin and ticlopidine, have been in usage to prevent for recurrent ischemic stroke. Triflusal is known to selectively inhibit cyclooxygenase in platelet rather than in vessel wall. And thus can be more beneficial in its antiplatelet aggregatory effect. There has been no comparative study between triflusal and ticlopidine on its antiplatelet aggregatory effect and side effects till now. Our comparative study between these two agents is to provide useful information on clinical utilization. METHODS: Triflusal(900mg/day) and ticlopidine(500mg/day) were administered in 31 and 37 patients, who suffered from acute ischemic stroke. Their efficacy in platelet aggregation and the incidence of clinical and laboratory side effects were compared in one week and one month after the administration of the drugs. RESULTS: Platelet aggregation was more effectively inhibited in triflusal group, especially induced by collagen or epinephrine(p<0.01). No significant difference was noted in the incidence of side effects in both groups. In five patients of the ticlopidine group, the drug was withdrawn due to skin rash and/or increased liver enzymes. CONCLUSION: Triflusal had more effectively inhibited platelet aggregation in this study. Severe side effects even requiring discontinuation of the drug were noted in five patients of ticlopidine group.
Aspirin
;
Blood Platelets
;
Collagen
;
Exanthema
;
Humans
;
Incidence
;
Liver
;
Platelet Aggregation
;
Platelet Aggregation Inhibitors
;
Prostaglandin-Endoperoxide Synthases
;
Stroke
;
Ticlopidine*
10.A study of effect on human epithelization by topical application of epidermal growth factor.
Hyeon Ok KIM ; Sung Moon CHUNG ; Seong Jong YOU ; Sung Soo KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1993;20(3):509-518
No abstract available.
Epidermal Growth Factor*
;
Humans*