1.The Effects of Oxalate on the DNA Synthesis in LLC-PK1 Cells.
Byong Chang JUNG ; Hyeon Hoe KIM ; Si Whang KIM
Korean Journal of Urology 2000;41(4):512-515
No abstract available.
Animals
;
DNA*
;
LLC-PK1 Cells*
;
Swine
2.Analysis of 35 cases of microsurgical resection and anstomosis in the management of the patjologic tubal occlusion.
Noh Hyeon PARK ; Young Chul YOO ; Chang Jae SHIN ; Jung Gu KIM ; Yoon Seok CHANG
Korean Journal of Obstetrics and Gynecology 1991;34(5):739-746
No abstract available.
Sterilization, Tubal*
3.Molecular Epidemiology of Fecal Oxalobacter formigenes in Healthy Adults Living in Seoul, Using a Polymerase Chain Reaction-Based Detection System.
Byong Chang JUNG ; Cheol KWAK ; Hee Kyung KIM ; Eui Chong KIM ; Hyeon Hoe KIM
Korean Journal of Urology 2000;41(12):1540-1545
No abstract available.
Adult*
;
Humans
;
Molecular Epidemiology*
;
Oxalobacter formigenes*
;
Seoul*
4.Prevalence and Trends of Isolated Systolic Hypertension among Korean Adults: the Korea National Health and Nutrition Examination Survey, 1998-2012.
Korean Circulation Journal 2015;45(6):492-499
BACKGROUND AND OBJECTIVES: Systolic and diastolic blood pressure may have different effects on cardiovascular disease, but limited data is available for hypertension subtypes in the Korean population. Thus, the prevalence, and absolute number of hypertension subtypes among Korean adults was estimated. SUBJECTS AND METHODS: The Korea National Health and Nutrition Examination Survey 1998-2012 was used to estimate the prevalence and absolute number of each hypertension subtype among Korean adults aged > or =20 years. Hypertension was classified into four subtypes: treated hypertension (TH), isolated systolic hypertension (ISH), isolated diastolic hypertension (IDH), and combined systolic and diastolic hypertension (SDH). RESULTS: In 2012, approximately 9.5 million adults were estimated to have hypertension, which consists of 5675671 TH (60.0%), 954253 ISH (10.1%), 1649486 IDH (17.4%), and 1175506 SDH (12.4%). Between 2010 and 2012, the proportion of IDH steadily decreased with age, but ISH increased especially in older ages (> or =40). Between 1998 and 2012, TH markedly increased from 1.4 million to 5.7 million while the number of untreated hypertension remained relatively constant. During the same time, the number of hypertensive elderlies increased from 507000 to 2822000 along with rapid ageing of the Korean population. Despite of significant improvement in treatment rate, there are still around 583000 elderlies with untreated hypertension (423000 ISH; 42000 IDH; 118000 SDH) as of 2012. CONCLUSION: Although the prevalence of hypertension has been constant over the last decades, absolute number of people with hypertension has been increasing. Along with the rapid population ageing, the number of elderly hypertension is increasing and the ISH is also becoming more prevalent.
Adult*
;
Aged
;
Blood Pressure
;
Cardiovascular Diseases
;
Humans
;
Hypertension*
;
Korea*
;
Nutrition Surveys*
;
Prevalence*
5.Clinical Analysis on the Outcome from the Treatment of Locally Invasive Cervical Cancer-Analysis of 195(Ia-IIb) Cases.
Soo Hyeon AHN ; Chang Ho CHO ; Eun Jeoung KANG ; Ki Tae KIM ; Hyun Chan KIM
Korean Journal of Obstetrics and Gynecology 1999;42(11):2576-2583
OBJECTIVES: The purposes of this clinical study were 1) to assess 5-year survival rates in 195 patients with locally invasive cervical cancer(stage Ia-IIb) treated by surgery, neoadjuvant chemotherapy+surgery and postoperative radiation in selected cases, 2) to evaluate the prognostic factors affecting the survival rate, and 3) to get helpful information for the better treatment. METHODS: A retrospective analysis was conducted of 195 patients. They were diagnosed and operated on during the period of Jan. 1988 - Dec. 1993 in Dept. of OB/Gyn, Pusan Paik Hospital, Inje Medical School. The 5-year survival rates were estimated using the Kaplan-Meier method, and prognostic factors were assessed using Wilcoxon test. RESULTS: The 5-year survival rates for FIGO stages Ia, Ib, IIa, and IIb were 100, 86.1, 76.9, and 81.1%, respectively. Factors that affect the 5-year survival rates were clinical stage(P=0.0001), cell type(small cell vs other, P=0.0001), depth of invasion(< or = 5 mm vs >5 mm, P=0.0013), tumor size(< or = 3 cm vs >3cm, P=0.0035), and lymph node metastasis(0 vs 1 vs more than 2, P=0.0001). There was no difference in 5-year survival rates between without neoadjuvant chemotherapy group and with neoadjuvant chemotherapy group which had poor prognostic factors. The predicted recurrence rate of the postoperative radiation group showed a lower 5-year survival rate than the no postoperative radiation group(P=0.0001). CONCLUSIONS: We conclude that the factors affecting the prognosis were FIGO stage, cell type, depth of invasion, tumor size, and lymph node metastasis, and speculated that the survival rates could be improved by using neoadjuvant chemotherapy for more advanced locally invasive cases properly.
Busan
;
Drug Therapy
;
Humans
;
Lymph Nodes
;
Neoplasm Metastasis
;
Prognosis
;
Recurrence
;
Retrospective Studies
;
Schools, Medical
;
Survival Rate
;
Uterine Cervical Neoplasms
6.Injury of Anterior Cruciate Ligament with Associated Bony Lesions: MR Image.
Soon KIM ; Yeon Hee OH ; Chang Wook LEE ; Yong Min KIM ; Hyeon Kyeong LEE ; Seung Hyeon KIM ; Sung Woo LEE
Journal of the Korean Radiological Society 1997;36(5):881-886
PURPOSE: To evaluate the characteristic MR findings in injury of the anterior cruciate ligament (ACL) with associated bony lesions. MATERIALS AND METHODS: We reviewed MR findings and the corresponding arthroscopic or operative results of 48 patients with ACL injuries, and evaluated ACL signal intensity and contour. In associated bony lesions, we determined the location of avulsion fracture and bony bruise. RESULTS: Cmplete ACL tears were seen in 27 cases, partial tears in 13, and avulsion injury in eight. Complete tears showed heterogeneously increased signal intensity with contour bulging in ten cases (37 %), and combined bony lesion in 14 (52 %). ACL with a thin continous low signal intensity band surrounding heterogeneously-increased signal intensity suggested partial tears, and was seen in three of 13 proven cases (23 %) of partial ACL tears ; combined bony lesion was seen in four such cases (31 %). There were eight cases of avulsion fracture ; the most frequent site was the anterolateral portion of the tibial spine (n=6). The most frequent sites of bony lesion were at the midportion of the lateral femoral condyle (n=6), and the posterior portion of the lateral tibial plateau (n=6) ; the next most frequent site was the anterior portion of the lateral tibial plateau (n=5). CONCLUSION: Tearing of the ACL was seen on MRI as ligament discontinuity, and heterogeneously increased signal intensity with ACL contour bulging. The most frequent sites of associated bony lesions were the midportion of the lateral femoral condyle, and the posterior portion of the lateral tibial plateau. In associated bony lesions, bony contusion suggested ACL tearing, but avulsion fracture suggested ligament avulsion injury without tear.
Anterior Cruciate Ligament*
;
Contusions
;
Humans
;
Ligaments
;
Magnetic Resonance Imaging
;
Spine
7.Low-attenuation mediastinal masses on CT.
Hee Suk LEE ; In Joo CHEONG ; Seung Hyeon KIM ; Shin Hyung LEE ; Chang Joon LEE
Journal of the Korean Radiological Society 1991;27(5):647-655
No abstract available.
8.Molecular Cloning and Nucleotide Sequence of the Gene Encoding Fusion(F) Protein of the Thermostable Newcastle Disease Virus Isolated from a Diseased Pheasant.
Kyung Soo CHANG ; Kui Hyun KIM ; Moo Hyung JUN ; Hee Jong SONG ; Jong Hyeon PARK
Journal of the Korean Society of Virology 1998;28(3):233-244
The gene encoding F protein of CBP-1 strain, a heat-stable Newcastle disease virus (NDV) isolated from the diseased pheasants in Korea, was characterized by reverse transcription-polymerase chain reaction (RT-PCR), nucleotide and amino acid sequences. Virus RNA was prepared from the chorioallatoic fluid infected with NDV CBP-1 virus and cDNA was amplified by RT-PCR, cloned and sequenced to analyze. The PCR was sensitive as to detect the virus titer above 25 hemagglutination unit. 1.7kb (1,707bp) size of the cDNA was amplified and cloned into BamHI site of pVL1393 Baculo transfer vector. The nucleotide sequences for F protein were determined by dye terminator cyclic sequencing using four pairs of primers, and 553 amino acid sequences were predicted. In comparison of the nucleotide sequence of F gene of CBP-1 with those of other NDV strains, the homology revealed 88.8%, 98.5% and 98.7% with Kyojungwon (KJW), Texas GB and Beaudette C strains, respectively. As the deduced 553 amino acid sequences of F protein of CBP-1 were compared with those of other NDV strains, the homology appeared 89.9%, 98.7% and 98.9% with KJW, Texas GB and Beaudette C strains, respectively. The putative protease cleavage site (112-116) was R-R-Q-K-R, indicating that CBP-1 strain is velogenic type. The amino acid sequences include 6 sites of N-asparagine-linked glycosylation and 13 cysteine residues. These data indicate that the genotype of CBP-1 strain is more closely associated with the strains of Texas GB and Beaudette C than KJW strain.
Amino Acid Sequence
;
Animals
;
Base Sequence*
;
Clone Cells
;
Cloning, Molecular*
;
Cysteine
;
DNA, Complementary
;
Genotype
;
Glycosylation
;
Hemagglutination
;
Korea
;
Newcastle disease virus*
;
Newcastle Disease*
;
Polymerase Chain Reaction
;
RNA
;
Texas
;
Viral Load
10.A Case of Congenital Nephrotic Syndrome.
Choong Sun KANG ; Chang Hee HWANG ; PyungKil KIM ; Hyeon Joo JEONG ; In Joon CHOI ; Jung Hye CHOI
Journal of the Korean Pediatric Society 1988;31(5):627-634
No abstract available.
Nephrotic Syndrome*