We aimed to study the clinicopathologic features of inflammatory fibroid polyp by histological and immunohistochemical methods. The materials used in this study consisted of 9 cases of inflammatory fibroid polyp: 4 in the stomach, 4 in the small intestine and 1 in the cecum. The results were as follows: Females were affected more frequently than males and the average age was 45 years(range:27-61). In cases of gastric lesion, the size tended to be smaller, the mass was mainly located along the greater curvature side of antrum, and confined to the submucosa. However inflammatory fibroid polyp of the small intestine was over 2.5 cm in size, located along the antemesenteric border, and involved the proper muscle layer. In addition, intussusception was accompanied by polyp in 2 cases of small intestinal lesions. Histologically inflammatory fibroid polyps of the stomach were characterized by prominent lymphocytic infiltration and occasional onion-skinning of stromal cells, whereas plasmocytic infiltration was prominent in those of the small intestine. Main component cells comprising this lesion were confirmed to be fibroblasts by immunohistochemistry which revealed strong reactivity to vimentin in the cytoplasm of slindle cells.
Female ; Male ; Humans

The localized eosinophilic granulomatous lesions of the stomach are rare benign tumorous conditions resembling submucosal tumors. They can be divided into two types. One is an inflammatory fibroid polyp. The other is an eosinophilic granuloma due to migration of Anisakis-type larva in the alimentary tract. The latter is usually found in the gastric body and anterior wall of the angle, and appears as a submucosal tumor. Histologically, the granuloma exhibits a characteristic lamellated structure consisting of a necrotic center with or without the worm, surrounded by layers of granulation tissue and eosinophilic infiltration. The present case is a 50 year-old male presenting with an episode of profuse melena. An emergency esophagogastroduodenoscopy revealed a 2x1.5cm sized, irregularly shaped ulcerative lesion with elevated margins and prominent folds convergence. Despite the endoscopic injection of hypertonic saline-epinephrine solution due to a recent bleeding stigmata, the patient experienced a rebleeding during hospitalization, The locally excised specimen showed an eosinophilic granuloma having a central necrosis. Although the larval body of Anisakis was not found, the lesion was diagnosed as a parasitic eosinophilic granuloma of the stomach.
Anisakis ; Christianity ; Emergencies ; Endoscopy, Digestive System ; Eosinophilic Granuloma* ; Eosinophils* ; Granulation Tissue ; Granuloma ; Hemorrhage* ; Hospitalization ; Humans ; Larva ; Leiomyoma ; Male ; Melena ; Middle Aged ; Necrosis ; Polyps ; Stomach* ; Ulcer

BACKGROUND/AIMS: Intrahepatic biliary stricture is one of the most common cause of treatment failure in hepatolithiasis, and it is also the main cause of stone recurrence. Ductal dilatation with percutaneous cholangioscopy is a promising therapy for biliary stricture, however the long- term outcome of this treatment modality has limited documentation. We performed the long-term follow up examination of these cases to investigate stone clearance and recurrence after percutaneous balloon dilatation, with or without stenting, and of stricture associated with intrahepatic cholelithiasis. METHODS: From October 1996 to December 1999, 28 patients with hepatolithiasis and intrahepatic biliary stricture were treated with percutaneous transhepatic cholangioscopic or postoperative cholangioscopic lithotripsy, and balloon dilatation. Choledochoscopic electrohydraulic lithotripsy was applied when impacted or large stones were encountered. We studied clinical and radiological examination regularly to evaluate the complete clearance and recurrence of stone after ductal dilatation. RESULTS: Complete clearance of stones was achieved in 23 patients (82.1%). The rate of stone recurrence in complete stone clearance group after mean follow up period of 41 months was 17.4%. CONCLUSIONS: Balloon dilatation is an efficient method of complete stone removal and prevention of the stone recurrence in biliary stricture-associated hepatolithiasis.
Cholelithiasis ; Constriction, Pathologic* ; Dilatation* ; Follow-Up Studies* ; Humans ; Lithotripsy ; Recurrence* ; Stents ; Treatment Failure