1.Clinical study of acute traumatic compartment syndrome.
Seong Beom BAE ; Sung Seok SEO ; Hyeon Deok YOO ; Young Chang KIM ; Jang Seok CHOI ; Young Goo LEE
The Journal of the Korean Orthopaedic Association 1993;28(2):641-653
No abstract available.
Compartment Syndromes*
2.Improved Bioethanol Production Using Activated Carbon-treated Acid Hydrolysate from Corn Hull in Pachysolen tannophilus.
Hyeon Beom SEO ; Seungseop KIM ; Hyeon Yong LEE ; Kyung Hwan JUNG
Mycobiology 2009;37(2):133-140
To optimally convert corn hull, a byproduct from corn processing, into bioethanol using Pachysolen tannophlius, we investigated the optimal conditions for hydrolysis and removal of toxic substances in the hydrolysate via activated carbon treatment as well as the effects of this detoxification process on the kinetic parameters of bioethanol production. Maximum monosaccharide concentrations were obtained in hydrolysates in which 20 g of corn hull was hydrolyzed in 4% (v/v) H2SO4. Activated carbon treatment removed 92.3% of phenolic compounds from the hydrolysate. When untreated hydrolysate was used, the monosaccharides were not completely consumed, even at 480 h of culture. When activated carbon-treated hydrolysate was used, the monosaccharides were mostly consumed at 192 h of culture. In particular, when activated carbon-treated hydrolysate was used, bioethanol productivity (P) and specific bioethanol production rate (Qp) were 2.4 times and 3.4 times greater, respectively, compared to untreated hydrolysate. This was due to sustained bioethanol production during the period of xylose/arabinose utilization, which occurred only when activated carbon-treated hydrolysate was used.
Carbon
;
Efficiency
;
Hydrolysis
;
Monosaccharides
;
Phenol
;
Zea mays
3.Estimation of Creatinine Clearance with Serum Creatinine in Korean Patients.
Woo Heon KANG ; Gi Hyeon SEO ; Bang Hoon LEE ; Beom KIM ; Sung Ku LEE ; Dong Jin OH ; Wooseong HUH ; Yoon Goo KIM ; Dae Joong KIM ; Ha Young OH
Korean Journal of Nephrology 1998;17(6):866-871
Cockcroft and Gault's formula is frequently used to estimate creatinine (Ccr) in clinical practice. To determine the accuracy of such estimation in Korean patients, we measured simultaneously, serum creatinine and 24-hour urinary creatinine excretion in 696 Korean patients (male:350, female:346). Measured Ccr was significantly different from estimated Ccr in several age groups and the decrease of creatinine excretion with age is less than Cockcroft and Gault's estimation. We assumed that this difference can be due to difference of the body habitus and difference of urinary creatinine excretion per body weight between different races. So we divided the sample population into two groups and derived the new formula in one group with regression analysis between age and 24 hour urinary creatinine excretion per body weight for estimation of Ccr as Cockcroft and Gault derived their formula and applied it to another group to compare the new formula with Cockcroft and Gault's formula in Korean patients. The new formula was Ccr (mL/min)=[ (260-age)x weight (kg)]/[160 x serumCr (mg/dL)] for male and Ccr (mL/min)-[ (236-age) x weight (kg)]/[180 x serum Cr (mg/dL)] for female. Predictive accuracy of the new formula was significantly better than the Cockcroft and Gault's formula in the other sample population and also in subgroup of the patients with azotemia.
Azotemia
;
Body Weight
;
Continental Population Groups
;
Creatinine*
;
Female
;
Glomerular Filtration Rate
;
Humans
;
Male
4.A Case of Constrictive Pericarditis due to Immunoglobulin G4-Related Disease.
Jiwon SEO ; In Ji SONG ; Sak LEE ; Hyeon Joo JEONG ; Hye Min KIM ; Beom Seok KOH ; Sung Ha PARK
Korean Circulation Journal 2015;45(2):161-164
Immunoglobulin G4-related disease (IgG4-RD) can involve any organ. The majority of reported cases involve IgG4-RD of the biliary tract or pancreas, while only two cases of pericarditis have been reported. A 58-year-old man visited the outpatient clinic of our institution with a seven-day history of progressive dyspnea. Based on his transthoracic echocardiogram and transesophageal echocardiogram, he was diagnosed with constrictive pericarditis. The histopathology of his pericardiectomy revealed the cause of constrictive pericarditis to be IgG4-RD. Prednisolone (40 mg) was initiated after the pericardiectomy. As the patient's symptoms resolved, he was discharged and followed-up on an outpatient basis. This is the first case report of constrictive pericarditis caused by IgG4-RD in Korea.
Ambulatory Care Facilities
;
Biliary Tract
;
Dyspnea
;
Humans
;
Immunoglobulin G
;
Immunoglobulins*
;
Inflammation
;
Korea
;
Middle Aged
;
Outpatients
;
Pancreas
;
Pericardiectomy
;
Pericarditis
;
Pericarditis, Constrictive*
;
Prednisolone
5.Clinical comparison of choledochal cystsbetween children and adults.
Sung Min JANG ; Beom Seok LEE ; Kun Kuk KIM ; Jung Nam LEE ; Yang Seo KOO ; Yeon Suk KIM ; Hyeon Young KIM ; Yeon Ho PARK
Korean Journal of Hepato-Biliary-Pancreatic Surgery 2011;15(3):157-163
BACKGROUNDS/AIMS: Choledochal cyst of the bile duct is characterized by cystic dilatation of the intra- or extrahepatic bile ducts. It is a relatively uncommon disease and there is still much controversy regarding its etiology as being congenital or acquired. METHODS: The medical records of 60 patients who underwent surgical treatments for choledochal cyst between April 1995 and April 2009 at the Gachon University Gil Hospital were reviewed retrospectively. To compare the clinical characteristics, patients under 19 years of age were grouped into children and the others were grouped into adults. RESULTS: Of the overall 60 patients, 24 were grouped into children and 36 were grouped into adults. Female predominance was common in both groups (M : F=1 : 6.5). The most common clinical symptom was abdominal pain (73.3%) in both groups. Children had remarkable jaundice (33.3% vs. 0%) and gastrointestinal symptoms including nausea and vomiting. Fever and chills were more common in children because of the associated complications of cholangitis. According to the Todani classification, type I was the most common form of choledochal cyst in both groups, and type IVa was significantly more common in children than adults (45.3% vs. 16.7%). Thirty patients (50%) had anomalous pancreaticobiliary ductal union which was confirmed by preoperative imaging studies or intraoperative cholangiography. All patients except for one child underwent cyst excision with hepaticojejunostomy. CONCLUSIONS: There was no significant difference in the clinical characteristics of choledochal cysts between children and adults. However, combined diseases especially bile duct malignancy were common in aged patients, early detection and more aggressive surgery is necessary for patients with choledochal cysts.
Abdominal Pain
;
Adult
;
Aged
;
Bile Ducts
;
Bile Ducts, Extrahepatic
;
Child
;
Chills
;
Cholangiography
;
Cholangitis
;
Choledochal Cyst
;
Dilatation
;
Female
;
Fever
;
Humans
;
Jaundice
;
Medical Records
;
Nausea
;
Retrospective Studies
;
Vomiting
6.Prevalence of Depressive Disorder among the Elderly Attending Community Health Center in a Small City.
Chul Woo PARK ; Jeong Seok SEO ; Hyeon Woo YIM ; Sun Jin JO ; Hyunsuk JEONG ; Beom Woo NAM
Journal of Korean Neuropsychiatric Association 2013;52(6):442-446
OBJECTIVES: This study was conducted in order to collect data regarding depressive disorder of elderly people at a community health center. METHODS: A total of 109 elderly people participated in this study. Trained examiners evaluated the general characteristics and symptoms of the subjects. Then the doctors conducted interviews with the elderly subjects in person and diagnosed depressive disorder according to the standard of Diagnostic and Statistical Manual of Mental Disorders-IV-TR. RESULTS: The prevalence of depressive disorder was 19.3%, major depressive disorder 10.1%, dysthymic disorder 1.8%, and others 7.3%. According to results of logistic regression analysis, in terms of demographic variables, the odds ratio of elementary school dropout compared with elementary school graduates was 3.60, after adjusting for age and sex. Thus, we found that elementary school dropout was associated with an increased risk of prevalence of depression. CONCLUSION: This is the first study of prevalence of depressive disorder in a primary health care center in Korea. Results of this study confirm that the prevalence of depressive disorder is two times higher among adults in the Chungju community. In addition, the level of education was also highly related. Examiners detected a possible relationship between sex and residence. The results will be helpful in conduct of future studies at the health care center.
Adult
;
Aged*
;
Community Health Centers*
;
Delivery of Health Care
;
Depression
;
Depressive Disorder*
;
Depressive Disorder, Major
;
Dysthymic Disorder
;
Education
;
Humans
;
Korea
;
Logistic Models
;
Odds Ratio
;
Prevalence*
;
Primary Health Care
;
Student Dropouts
7.Economic Impact of Atopic Dermatitis in Korean Patients.
Chulmin KIM ; Kui Young PARK ; Seohee AHN ; Dong Ha KIM ; Kapsok LI ; Do Won KIM ; Moon Beom KIM ; Sun Jin JO ; Hyeon Woo YIM ; Seong Jun SEO
Annals of Dermatology 2015;27(3):298-305
BACKGROUND: Atopic dermatitis is a global public health concern owing to its increasing prevalence and socioeconomic burden. However, few studies have assessed the economic impact of atopic dermatitis in Korea. OBJECTIVE: We conducted a cost analysis of atopic dermatitis and evaluated its economic impacts on individual annual disease burden, quality of life, and changes in medical expenses with respect to changes in health related-quality of life. METHODS: The cost analysis of atopic dermatitis was performed by reviewing the home accounting records of 32 patients. The economic impact of the disease was evaluated by analyzing questionnaires. To handle uncertainties, we compared the results with the data released by the Health Insurance Review & Assessment Board on medical costs claimed by healthcare facilities. RESULTS: The direct cost of atopic dermatitis per patient during the 3-month study period was 541,280 Korean won (KRW), and expenditures on other atopic dermatitis-related products were 120,313 KRW. The extrapolated annual direct cost (including expenditures on other atopic dermatitis-related products) per patient was 2,646,372 KRW. The estimated annual indirect cost was 1,507,068 KRW. Thus, the annual cost of illness of atopic dermatitis (i.e., direct+indirect costs) was estimated to be 4,153,440 KRW. CONCLUSION: The annual total social cost of atopic dermatitis on a national level is estimated to be 5.8 trillion KRW.
Cost of Illness
;
Costs and Cost Analysis
;
Delivery of Health Care
;
Dermatitis, Atopic*
;
Health Expenditures
;
Humans
;
Insurance, Health
;
Korea
;
Prevalence
;
Public Health
;
Quality of Life
;
Surveys and Questionnaires
8.Conservative treatment of dentigerous cysts; 5 cases.
Chang Hun JUN ; Jong Cheol JEONG ; Min Seok SONG ; Ji Hoon SEO ; Sung Beom KIM ; Se Hoon CHOI ; Hyeon Min KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2003;29(2):135-139
A dentigerous cyst is an epithelium-lined sac that surrounds the crown of an unerupted tooth or odontoma. And the most common sites of this cyst are the mandibular and maxillary third molar and maxillary cuspid areas. Clinically, expansion of bone with subsequent facial asymmetry, extreme displacement of teeth, severe root resorption of adjacent teeth and pain are all possible sequelae of this cyst. The standard treatment for a dentigerous cyst is enucleation and extraction of the involved tooth. But in large cysts, this can lead to functional, cosmetic and psychologic consequences to the patients. So recently, more conservative methods are used. We report 5 cases of dentigerous cysts in pediatric patient which were treated by a conservative approach, By this methods, we can preserve teeth and guide eruption of the teeth which are involved in cystic area.
Crowns
;
Cuspid
;
Dentigerous Cyst*
;
Facial Asymmetry
;
Humans
;
Molar, Third
;
Odontoma
;
Root Resorption
;
Tooth
;
Tooth, Unerupted
9.Mucinous carcinoma is a predictive factor for the risk of open conversion from laparoscopic colectomy in colorectal cancer
Ah Jung SEO ; Jung Kyoung SHIN ; Yoon Ah PARK ; Jung Wook HUH ; Yong Beom CHO ; Hee Cheol KIM ; Seong Hyeon YUN ; Woo Yong LEE
Korean Journal of Clinical Oncology 2019;15(2):72-78
PURPOSE: Although laparoscopic surgery is widely accepted in the treatment of colorectal cancer, conversion to open surgery is associated with the rate of unfavorable outcomes. The aim of this study was to determine the factors associated with open conversion from laparoscopic surgery for colorectal cancer.METHODS: A total of 3,002 patients who underwent laparoscopic colectomy as an initial plan for the treatment of colorectal cancer located from the sigmoid colon to the rectum were retrospectively evaluated between January 2009 and December 2018 at Samsung Medical Center in Korea. Risk factors significantly associated with open conversion were determined using univariate and multivariate regression models.RESULTS: Among the 3,002 patients, open conversion was performed in 120 patients (4%). Age >60 years (adjusted odds ratio [AOR], 2.370), preoperative bowel obstruction (AOR, 2.348), clinical T4 stage (AOR, 2.201), and serum carcinoembryonic antigen level >5 ng/mL (AOR, 2.289) were significantly associated with open conversion. Moreover, mucinous carcinoma was a significantly more frequent histopathologic type than adenocarcinoma (10.0% vs. 3.2%, P<0.001) in the open conversion group with an AOR of 2.549 (confidence interval, 1.259–5.159; P=0.009).CONCLUSION: The present study presented a novel finding, i.e. mucinous carcinoma as the histopathologic type could be an independent predictive factor for conversion from laparoscopic colectomy to open surgery. Identifying patients with mucinous carcinoma will help stratify the risk of open conversion preoperatively.
Adenocarcinoma
;
Adenocarcinoma, Mucinous
;
Carcinoembryonic Antigen
;
Colectomy
;
Colon, Sigmoid
;
Colorectal Neoplasms
;
Conversion to Open Surgery
;
Humans
;
Korea
;
Laparoscopy
;
Mucins
;
Odds Ratio
;
Rectum
;
Retrospective Studies
;
Risk Factors