1.Abnormal Uterine Bleeding Due to Vascular Abnormality Caused by D&E : Doppler Sonography for Diagnosis and Transcatheter Arterial Embolization for Treatment.
Yong Jo KIM ; Chan HEO ; Tae Gun JUNG ; Gi Sung KIM ; Hyeok Po KWON ; Sang Kwon LEE ; Jung Hyeok KWON ; Yeong Hwan LEE
Journal of the Korean Radiological Society 1996;34(6):817-823
PURPOSE: We attempted to evaluate the usefulness of Doppler sonography in the diagnosis of uterine vascular abnormality caused by previous D&E, and to report that transarterial embolization is an exceelent treatment modality. MATERIALS & METHODS: We analyzed gray-scale US, color/duplex Doppler US and angiographic findings inseven patients with radiologically proven uterine vascular abnormality. Two of the seven cases were pseudoaneurysms and five of the seven cases were AVMs. In one of the AVMs, two small pseudoaneurysms were combined. In all cases, transarterial embolizations using 3mm coil or/and gelfoam particles were performed. Follow-up US studies, including color Doppler US, were performed. RESULTS: On color/duplex Doppler sonography, two cases of pseudoaneurysm showed blood pools with turbulent arterial flow, and five cases of AVM showed asymmetrically increased vascularity, with variable high velocities composed of the pulsatie arterial flow, with ahigh diastoic component. On angiography, the former showed pseudoaneurysmal sacs, and the latter densely opacified vascular tangles. No more abnormal uterine bleeding was shown, following transarterial embolization in all cases. CONCLUSION: Color/duplex Doppler sonography was valuable in the diagnosis or treatment of abnormal uterine bleeding caused by uterine vascular abnormality such as acquired AVM or pseudoaneurysm.
Aneurysm, False
;
Angiography
;
Diagnosis*
;
Gelatin Sponge, Absorbable
;
Humans
;
Uterine Artery
;
Uterine Hemorrhage*
2.Abdominal Ultrasonographic Findings of Salmonellosis.
Yeong Hwan LEE ; Dong Heon OH ; Tae Gun JUNG ; Jung Hyeok KWON ; Yong Jo KIM ; Gi Sung KIM ; Sang Kwon LEE
Journal of the Korean Radiological Society 1995;32(3):455-459
PURPOSE: We evaluated the abdominal uttrasonographic findings of Salmonellosis. MATERIALS AND METHODS: This study included 64 patients who were confirmed as salmonellosis by blood culture. We retrospectively analyzed the abdominal ultrasonographic findings with particular attention to enlarged mesenteric lymph nodes(mesenteric lymphadenitis), thickening of bowel wall, especially terminal ileum and cecum(ileocecitis), hepatosplenomegaly, ascites, gallbladder wall thickening, and enlarged lymph nodes in porta hepatis. RESULTS: The 64 cases were observed as mesenteric lymph node enlargement(44 cases), wall thickening of the terminal ileum and cecum(36 cases), hepatomegaly and/or splenomegaly(42 cases), minimal ascites(8 cases), gallbladder wall thickening(6 cases), and enlarged lymph nodes in porta hepatis(4 cases). No abnormal finding was seen in 10 patients. CONCLUSION: The mesenteric lymph node enlargement, wall thickening of the terminal ileum and cecum, hepatomegaly and/or splenomegaly, minimal ascites, gallbladder wall thickening, and enlarged lymph nodes in porta hepatis are suggestive findings of salmonellosis on abdominal ultrasonography in patients with fever and acute abdomen.
Abdomen, Acute
;
Ascites
;
Cecum
;
Fever
;
Gallbladder
;
Hepatomegaly
;
Humans
;
Ileum
;
Lymph Nodes
;
Retrospective Studies
;
Salmonella Infections*
;
Splenomegaly
;
Ultrasonography
3.Mucosa-associated Lymphoid Tissue Lymphoma of the Rectum: A case report.
Yu Na KANG ; Sun Young KWON ; Sang Pyo KIM ; Kwan Kyu PARK ; Kun Young KWON ; Sang Sook LEE ; Kyung Sik PARK ; Jung Hyeok KWON ; Chul Hyun KIM
Journal of the Korean Society of Coloproctology 2003;19(6):394-398
Primary colorectal lymphoma accounts for only 0.2~.65% of large intestinal malignancies. Mucosa-associated lymphoid tissue lymphoma in the rectum is very rare. We report the case of a 73-year-old woman with morphologic and immunophenotypic findings consistent with mucosa-associated lymphoid tissue lymphoma of the rectum. The woman complained of consistent bloody diarrhea and recently developed abdominal pain, febrile and chilling sensation. Ultrasonography of upper abdomen detected multiple stones within the gallbladder and the gallbladder was resected using laparoscopic surgery. An ulcerative polypoid mass in the rectum was detected by colonoscopy and computerized tomography of abdomen. Microscopic and immunohistochemical studies showed a diagnosis of mucosa-associated lymphoid tissue (MALT) lymphoma. This patient was consulted to the department of radiotherapy because of poor general condition and old age. Chemotherapy was not performed. She was followed up with no relapse of the lesions during 7 months after the diagnosis.
Abdomen
;
Abdominal Pain
;
Aged
;
Colonoscopy
;
Diagnosis
;
Diarrhea
;
Drug Therapy
;
Female
;
Gallbladder
;
Humans
;
Laparoscopy
;
Lymphoid Tissue
;
Lymphoma
;
Lymphoma, B-Cell, Marginal Zone*
;
Radiotherapy
;
Rectum*
;
Recurrence
;
Sensation
;
Ulcer
;
Ultrasonography
4.A Case of Alveolar Rhabdomyosarcoma of the Ethmoid Sinus Invading the Orbit in an Adult.
Hyun Seung MOON ; Sang Won KWON ; Jong Hyeok LEE
Korean Journal of Ophthalmology 2006;20(1):70-75
PURPOSE: A case study and literature review of alveolar rhabdomyosarcoma (RMS) in an adult. METHODS: A 48-year-old male patient presented at our clinic complaining of proptosis that had persisted for 2 weeks in his left eye. A computed tomography (CT) scan revealed a destructive soft-tissue mass in the left ethmoid sinus with invasion of the left orbit and compression of the medial rectus muscle. Endoscopic intranasal biopsy revealed alveolar RMS. Conservative debulking and orbital wall decompression were performed. RESULTS: Immunohistochemical testing was positive for desmin, S-100, and smooth muscle actin (SMA), supporting the diagnosis of RMS. Since ipsilateral cervical and spinal metastasis was detected, systemic treatment was administered simultaneously. CONCLUSIONS: Although rarely found in adults, RMS should be considered in the differential diagnosis of orbital tumors. Immunohistochemical analysis plays an important role in the definitive diagnosis of RMS.
Tomography, X-Ray Computed
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Rhabdomyosarcoma, Alveolar/*pathology/radiography
;
Paranasal Sinus Neoplasms/*pathology/radiography
;
Orbital Neoplasms/*pathology/radiography
;
Neoplasm Invasiveness
;
Middle Aged
;
Male
;
Magnetic Resonance Imaging
;
Humans
;
*Ethmoid Sinus
;
Diagnosis, Differential
;
Biopsy
5.Posttraumatic Intestinal Stenosis.
Seung Wan RYU ; In Ho KIM ; Jung Hyeok KWON ; Soo Sang SOHN
Journal of the Korean Surgical Society 2003;65(5):461-463
We report a case of posttraumatic intestinal stenosis (PIS), an uncommon sequela of blunt abdominal trauma, in which injury to the mesentery and bowel wall results in later focal ischemic stricture of that segment. We present CT images at the time of trauma and 3 weeks later when clinical signs of intestinal obstruction occurred. At surgery, a stenotic small bowel loop was found adjacent to a healed defect in the mesentery. Histologic examination of the resected segment showed mucosal and submucosal ischemia with mucosal ulceration, mural inflammation, and fibrosis. PIS subsequent to a mesenteric tear should be included in the differential diagnosis for a patient with a history of blunt abdominal trauma and signs of intestinal obstruction.
Constriction, Pathologic*
;
Diagnosis, Differential
;
Fibrosis
;
Humans
;
Inflammation
;
Intestinal Obstruction
;
Ischemia
;
Mesentery
;
Ulcer
6.Rituximab Biosimilar Prevents Poor Outcomes of Microscopic Polyangiitis and Granulomatosis with Polyangiitis as Effectively as Rituximab Originator
Hyeok Chan KWON ; Minyoung Kevin KIM ; Jason Jungsik SONG ; Yong-Beom PARK ; Sang-Won LEE
Yonsei Medical Journal 2020;61(8):712-719
Purpose:
There has been no extensive study to compare the efficacy between rituximab originator (Mabthera®) and its biosimilar (Truxima®) for microscopic polyangiitis (MPA) and granulomatosis with polyangiitis (GPA). Here, we investigated the clinical effects of rituximab on poor outcomes of MPA and GPA in Korean patients, and compared those between Mabthera® and Truxima®.
Materials and Methods:
We retrospectively reviewed the medical records of a total of 139 patients, including 97 MPA patients and 42 GPA patients. At diagnosis, antineutrophil cytoplasmic antibody positivity and comorbidities were assessed. During follow-up, all-cause mortality, relapse, end-stage renal disease, cerebrovascular accident and acute coronary syndrome were evaluated as poor outcomes. In this study, rituximab was used as either Mabthera® or Truxima®.
Results:
The median age at diagnosis was 60.1 years and 46 patients were men (97 MPA and 42 GPA patients). Among poor outcomes, patients receiving rituximab exhibited a significantly lower cumulative relapse-free survival rate compared to those not receiving rituximab (p=0.002). Nevertheless, rituximab use did not make any difference in other poor outcomes of MPA and GPA except for relapse, which might be a rebuttal to the fact that rituximab use after relapse eventually led to better prognosis. There were no significant differences in variables at diagnosis and during follow-up between patients receiving Mabthera® and those receiving Truxima®. Patients receiving Truxima® exhibited a similar pattern of the cumulative survival rates of each poor outcome to those receiving Mabthera®.
Conclusion
Truxima® prevents poor outcomes of MPA and GPA as effectively as does Mabthera®.
7.Management of Complications during Below-the-Knee Endovascular Treatment: A Technical Note
JeeYoung MIN ; Sang Woo PARK ; Jin Ho HWANG ; Yong Wonn KWON ; Dong Hyeok SHIN
Korean Journal of Radiology 2020;21(8):935-945
We retrospectively reviewed the cases in which complications occurred during below-the-knee (BTK) endovascular treatmentsthat were performed at our hospital from 2005 to 2014. Several interesting cases have been described herein. All the patientshad diabetes and non-healing wounds on their feet and/or rest pain in their foot or leg, and therefore, endovascular treatmentwas performed for the BTK arteries of the affected lower extremity. The complications that occurred during the procedure wereclassified into six categories—vascular spasm, flow limiting dissection, perforation, broken guidewire, distal thromboembolism,and unusual puncture site bleeding. Each complication has its own solutions and management. We discuss these different classesof complications and describe how cases of each type were managed.
8.Antineutrophil Cytoplasmic Antibody Positivity Is Associated with Vascular Involvement in Behçet’s Disease
Minyoung Kevin KIM ; Hyeok Chan KWON ; Jason Jungsik SONG ; Yong-Beom PARK ; Sang-Won LEE
Yonsei Medical Journal 2021;62(2):149-158
Purpose:
We investigated whether antineutrophil cytoplasmic antibody (ANCA) positivity is associated with vascular manifestations at diagnosis of Behçet's disease (BD) and poor outcomes during follow-up.
Materials and Methods:
We retrospectively reviewed the medical records of 1060 patients with BD. Among them, 808 patients could be diagnosed with BD based on the revised version of the International Criteria for Behçet's Disease (ICBD) in 2014 (2014 ICBD criteria) and 588 patients could be diagnosed with BD based on the International Study Group (ISG) criteria proposed in 1990 (1990 ISG criteria). We examined the sites and patterns of vascular involvement in the BD patients at diagnosis and evaluated adverse outcomes during follow up, such as all-cause mortality, acute coronary syndrome, and deep vein thrombosis.
Results:
Among the 808 patients with BD based on the 2014 ICBD criteria, the rate of ANCA positivity at diagnosis was 2.2%. ANCA-positive BD patients exhibited a higher frequency of overall vascular manifestations (22.2% vs. 6.1%) and higher frequencies of vascular involvement in the upper extremities and visceral arteries than ANCA-negative BD patients (5.6% vs. 0.1% and 5.6% vs. 0.1%). Among the 588 BD patients based on the 1990 ISG criteria, similarly, ANCA-positive BD patients exhibited a higher frequency of vascular manifestations than ANCA-negative BD patients. ANCA positivity, however, did not seem to be associated with poor outcomes in BD patients during follow up.
Conclusion
ANCA positivity in BD patients was found to be associated with cross-sectional vascular involvement in the upper extremities and visceral arteries at diagnosis but was not predictive of poor outcomes during follow-up.
9.Concurrence of Spatially Separated Medullary Carcinoma and Papillary Carcinoma of the Thyroid Gland: A Report of Three Cases.
Changyoung YOO ; Chan Kwon JUNG ; Hyeok Sang KWON ; Sung Hun KIM ; Min Sik KIM ; Seung Nam KIM ; Kyo Young LEE
Korean Journal of Pathology 2007;41(3):207-212
Although medullary thyroid carcinoma (MTC) may coexist with papillary thyroid carcinoma (PTC) as a collision tumor within the same nodule or as two or more spatially separated tumors, these two carcinomas rarely coexist. We encountered three cases of sporadic MTCs spatially separated from PTCs, which occurred concurrently, either within the same thyroid lobe or in different thyroid lobes. In each of the cases the patients underwent total thyroidectomy and neck dissection. PTC metastases of the lymph node were observed in two of the cases and MTC metastasis of the lymph node was observed in one case. Among the multiple thyroid nodules affected by both MTCs and PTCs, only the dominant nodules had spread to the lymph nodes. Because MTC has a different clinical significance from PTC, in patients with multiple thyroid nodules, appropriate diagnostic approaches, such as fine needle aspiration of all possible nodules and measurement of serum calcitonin level, should be performed.
Biopsy, Fine-Needle
;
Calcitonin
;
Carcinoma, Medullary*
;
Carcinoma, Papillary*
;
Humans
;
Lymph Nodes
;
Neck Dissection
;
Neoplasm Metastasis
;
Thyroid Gland*
;
Thyroid Neoplasms
;
Thyroid Nodule
;
Thyroidectomy
10.Fish Bone as a Nidus for Stone Formation in the Common Bile Duct: Report of Two Cases.
Young Hwan KIM ; Yong Joo KIM ; Won Kyu PARK ; Sang Kwon LEE ; Jung Hyeok KWON ; Seong Ku WOO
Korean Journal of Radiology 2004;5(3):210-213
We report two cases of common bile duct stone formed around a fish bone which migrated from the intestinal tract, along with their characteristic imaging findings. Two patients who had no history of previous operation were admitted because of cholangitis. Percutaneous transhepatic biliary drainage (PTBD) was performed and the cholangiogram showed filling defects with an unusually elongated shape in the common bile duct. After improvement of the cholangitic symptoms, the stones were removed through the PTBD tract under fluoroscopic guidance. A nidus consisting of a 1.5 cm sized fish bone was found in each stone removed.
Aged
;
Animals
;
Bone and Bones/*radiography/*ultrasonography
;
Cholangiography
;
Cholangitis/etiology
;
Choledocholithiasis/*etiology/surgery
;
Female
;
Fishes
;
Foreign Bodies/*complications/surgery
;
Humans
;
Male