1.A Case of Invasive Fungal Sinusitis after Kidney Transplantation.
Nam Sik KIM ; Sung Han YUN ; Seung Eun LEE ; Hyeo Ju O ; Young Ki SON ; Yong Hun SIN ; Jung Kyung KIM
Korean Journal of Nephrology 2009;28(4):370-374
Acute fulminant invasive fungal sinusitis in an immunocompromised host and bacterial rhinosinusitis with intracranial or orbital extension is challenging to manage. And it sometimes constitutes true otolaryngologic emergencies. In the absence of rapid diagnosis and treatment, these diseases can be fatal. A 57-year-old female was admitted for chills and headache, who received a deceased donor renal transplantation 3 months ago. Paranasal sinus CT showed enhanced soft tissue density and MRI showed low-signal with hyperintense signal of around paranasal sinus cavity. The histological investigation revealed invasive aspergillosis of paranasal sinuses. Clinical improvement occurred after endoscopic sinus surgery and post-operative systemic antifungal therapy with amphotericin B and voriconazole.
Amphotericin B
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Aspergillosis
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Chills
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Emergencies
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Female
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Headache
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Humans
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Immunocompromised Host
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Kidney
;
Kidney Transplantation
;
Middle Aged
;
Orbit
;
Paranasal Sinuses
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Pyrimidines
;
Sinusitis
;
Tissue Donors
;
Triazoles