1.Clinical Study of cornual pregnancy and comparative Study of Laparoscopic surgery versus Laparotomy.
Hyen Rak PAK ; Soon Chul KWON ; In Goo KANG ; Sang Eon LEE ; Tae Woo KIM ; Yoon Sik HA ; Seung Chul KANG ; Seok WON ; Jeong Keun PARK
Korean Journal of Obstetrics and Gynecology 2001;44(10):1812-1816
Most of treatments have been performed laparotomy, but the rapid advances in laparoscopic operative and laboratory techniques and instrument allowed to apply laparoscopic surgery to this disease. We have reviewed 342 cases of ectopic pregnancy from march 1994 to march 2001.The cornual pregnancies were 21 case (6.1%), and the laparoscopic management in 11 cases. The mean gestational age at the time of laparoscopic surgery was 9.1 1.2 (n=11) weeks, and laparotomy was 9.4 1.3 (n=10) weeks. There were no significant difference. The mean operation time of laparoscopic surgery was 72.8 25.5minutes, and laparotomy was 68.3 24.3minutes. The mean hospital days of laparoscopic surgery were 4.9 2.4days, and laparotomy were 6.6 2.3days. In conclusion, laparoscopic surgery can be used as effective and safe as laparotomy for cornual pregnancy.
Female
;
Gestational Age
;
Laparoscopy*
;
Laparotomy*
;
Pregnancy*
;
Pregnancy, Ectopic
2.Acute Pulmonary Oxygen Toxicity in Rats: Findings and Lung Density Changes in High Resolution Computed Tomography.
Dae Sik RYU ; Kun Sang KIM ; Kil Hyen KANG ; Haing Sup CHUNG ; Bung Wok LEE ; Young Ki KIM ; Tae Keun LEE ; Nam Hyeon KIM ; Seung Mun JUNG ; Man Soo PARK
Journal of the Korean Radiological Society 2000;42(3):473-480
PURPOSE: To evaluate imaging findings and lung density changes after 95% oxygen inhalation in rat. MATERIALS AND METHODS: A total of 18 rats were divided into three groups on the basis of inhalation time: group I(n=6) inhaled 95 % oxygen for 24 hours, and group II(n=6) for 48 hours, group III(n=6) for 60 hours. A control group(n=6) inhaled room air(21% oxygen). Chest radiograph and high resolution computed tomography were performed, and pathologic and imaging findings were compared. RESULTS: Chest radiograph showed abnormality only in group III. High resolution CT, however, revealed abnormal findings in all three groups : diffuse ground glass opacity in groups I, II and III, additional focal patchy consolidation at the peripheral portion in group II, and diffuse consolidation in group III. Lung density was sig-nificantly higher in group I than in controls(p <0.05), while density in group II was not significantly different from that in group I(p >0.05). In group III, density was significantly higher than in group II. The lung density changes seen in all groups showed a bilateral diffuse increased pattern. but, in group III, changes were more severe in the central, peripheral and posterior portion of the lower lung. Ground glass opacity and focal patchy consolidaton seen on HRCT were found on pathologic examination to be due to alveolar cell hyperplasia and septal thickening. Consolidation was caused by alveolar edema and hemorrage. Pathologic lesions were randomly distributed in both lungs. CONCLUSION: One HRCT images, rat exposed to hyperoxia showed ground glass opacity, patchy consolidation and diffuse consolidation. Depending on exposure time, the pathologic findings also indicated increased lung density and a bilateral, diffuse distribution pattern, as well as alveolar cell hyperplasia and septal thickening, alveolar edema and hemorrage. HRCT may be more helpful than simple X-rays for the early detection of pulmonary oxygen toxicity.
Animals
;
Edema
;
Glass
;
Hyperoxia
;
Hyperplasia
;
Inhalation
;
Lung*
;
Oxygen*
;
Radiography, Thoracic
;
Rats*
3.Intrathoracic Migration of Steinmann Pin.
Sang Soon PARK ; Shin Kwang KANG ; Kwan Woo KU ; Myung Hoon NA ; Jae Hyen YU ; Seung Pyung LIM ; Young LEE
The Korean Journal of Thoracic and Cardiovascular Surgery 2001;34(6):511-513
Migration of Steinmann pins into the thoracic cavity is uncommon, but when occurs it can bring devasting consequences. A Sixty-year-old woman had pinning of the right humerus surgical neck fracture. She was not followed up after discharge. Two years later, a chest x-ray film and chest CT showed that the pin had migrated to the right hemithorax. The migrated pins were removed with right anterolateral thoracotomy incision without any difficulties.
Female
;
Humans
;
Humerus
;
Neck
;
Thoracic Cavity
;
Thoracotomy
;
Thorax
;
Tomography, X-Ray Computed
;
X-Ray Film
4.Effects of Repeated Citalopram Treatments on Chronic Mild Stress- Induced Growth Associated Protein-43 mRNA Expression in Rat Hippocampus.
Sang Ha PARK ; Song hyen CHOI ; Jimin LEE ; Seungwoo KANG ; You Chan SHIN ; Hyun Ju KIM ; Hyun Jung KIM ; Seung Keon SHIN ; Min Soo LEE ; Kyung Ho SHIN
The Korean Journal of Physiology and Pharmacology 2008;12(3):117-123
Although growth associated protein-43 (GAP-43) is known to play a significant role in the regulation of axonal growth and the formation of new neuronal connections in the hippocampus, there is only a few studies on the effects of acute stress on GAP-43 mRNA expression in the hippocampus. Moreover, the effects of repeated citalopram treatment on chronic mild stress (CMS)-induced changes in GAP-43 mRNA expression in the hippocampus have not been explored before. To explore this question, male rats were exposed to acute immobilization stress or CMS. Also, citalopram was given prior to stress everyday during CMS procedures. Acute immobilization stress significantly increased GAP-43 mRNA expression in all subfields of the hippocampus, while CMS significantly decreased GAP-43 mRNA expression in the dentate granule cell layer (GCL). Repeated citalopram treatment decreased GAP-43 mRNA expression in the GCL compared with unstressed controls, but this decrease was not further potentiated by CMS exposure. Similar decreases in GAP-43 mRNA expression were observed in CA1, CA3 and CA4 areas of the hippocampus only after repeated citalopram treatment in CMS-exposed rats. This result indicates that GAP-43 mRNA expression in the hippocampus may differently respond to acute and chronic stress, and that repeated citalopram treatment does not change CMS-induced decreases in GAP-43 mRNA expression in the GCL.
Animals
;
Axons
;
Citalopram
;
GAP-43 Protein
;
Hippocampus
;
Humans
;
Immobilization
;
Male
;
Neurons
;
Rats
;
RNA, Messenger
5.The Survey of Recognition about Rehabilitative Robots for Treatmentin Physical Therapists
Hyosuk KIM ; Dong Jin KANG ; Deok Hyen KIM ; Seo Jeong PARK ; Seong Yong LEE ; Jeong Min LEE ; Seung Yeon JO ; Bo Ram CHOI ; Minhee KIM
Journal of Korean Physical Therapy 2021;33(2):69-75
Purpose:
This study examined the recognition of rehabilitative robots for treatment in physical therapists.
Methods:
This study surveyed 100 physical therapists in Seoul and Gyeonggi-do using Google Form, an online survey tool. The questionnaire consisted of 21 questions, including eight questions on the general characteristics, 13 questions on the recognition of rehabilitative robots.
Results:
The general characteristics of the physical therapists showed differences and influences on recognition of rehabilitative robots, and there were statistically significant differences. There were significant differences in the recognition of rehabilitation robots according to general characteristics in gender, age, education degree, type of hospital, average weekly working time, and treatment field. Multiple regression analysis found that gender and the type of hospital influenced the recognition of rehabilitation robots.
Conclusion
Physical therapists showed differences in recognition of rehabilitative robots according to their general characteristics, and gender and the type of hospital influence the recognition of rehabilitation robots. Sufficient systematic education programs should be provided, and physical therapists require policy adjustments to increase their accessibility to rehabilitation robots through continuing education.
6.A clinico-epidemiological multicenter study of herpes zoster in immunocompetent and immunocompromised hospitalized children
Ji Hyen HWANG ; Ki Hwan KIM ; Seung Beom HAN ; Hyun Hee KIM ; Jong Hyun KIM ; Soo Young LEE ; Ui Yoon CHOI ; Jin Han KANG
Clinical and Experimental Vaccine Research 2019;8(2):116-123
PURPOSE: There are limited population-based data regarding herpes zoster in children. Thus we conducted a multi-institutional epidemiological analysis of herpes zoster in children and comparative analysis according to their immune status. MATERIALS AND METHODS: The study included 126 children under the age of 18 years who were hospitalized for herpes zoster at 8 hospitals in South Korea, between July 2009 and June 2015. The subjects were divided into 2 groups according to their immune status, and medical records were reviewed. RESULTS: There were 61 cases (48.4%) in the immunocompetent group and 65 cases (51.6%) in the immunocompromised group. Median age was older in immunocompromised group (11.4 vs. 8.6) (p<0.001). The mean duration of hospitalization was longer in immunocompromised group (11.0 vs. 6.6) (p<0.001). Patients were treated with oral or intravenous antiviral agents. A total of 12 in immunocompetent group were cured only by oral acyclovir. No treatment failure was found in both groups. Six immunocompromised patients had postherpetic neuralgia and 1 case was in immunocompetent group. In immunocompetent children, herpes zoster was likely caused by early varicella infection. There was no increase in progression of severity in both groups due to appropriate treatment. CONCLUSION: Early initiation of therapy is necessary for those in immunocompromised conditions. And inactivated herpes zoster vaccination may be considered in immunocompromised adolescents in the future.
Acyclovir
;
Adolescent
;
Antiviral Agents
;
Chickenpox
;
Child
;
Child, Hospitalized
;
Herpes Zoster
;
Hospitalization
;
Humans
;
Immunocompromised Host
;
Korea
;
Medical Records
;
Neuralgia, Postherpetic
;
Treatment Failure
;
Vaccination
7.The Survey of Recognition about Rehabilitative Robots for Treatmentin Physical Therapists
Hyosuk KIM ; Dong Jin KANG ; Deok Hyen KIM ; Seo Jeong PARK ; Seong Yong LEE ; Jeong Min LEE ; Seung Yeon JO ; Bo Ram CHOI ; Minhee KIM
Journal of Korean Physical Therapy 2021;33(2):69-75
Purpose:
This study examined the recognition of rehabilitative robots for treatment in physical therapists.
Methods:
This study surveyed 100 physical therapists in Seoul and Gyeonggi-do using Google Form, an online survey tool. The questionnaire consisted of 21 questions, including eight questions on the general characteristics, 13 questions on the recognition of rehabilitative robots.
Results:
The general characteristics of the physical therapists showed differences and influences on recognition of rehabilitative robots, and there were statistically significant differences. There were significant differences in the recognition of rehabilitation robots according to general characteristics in gender, age, education degree, type of hospital, average weekly working time, and treatment field. Multiple regression analysis found that gender and the type of hospital influenced the recognition of rehabilitation robots.
Conclusion
Physical therapists showed differences in recognition of rehabilitative robots according to their general characteristics, and gender and the type of hospital influence the recognition of rehabilitation robots. Sufficient systematic education programs should be provided, and physical therapists require policy adjustments to increase their accessibility to rehabilitation robots through continuing education.
8.Imaging follow-up strategy after endovascular treatment of Intracranial aneurysms: A literature review and guideline recommendations
Yong-Hwan CHO ; Jaehyung CHOI ; Chae-Wook HUH ; Chang Hyeun KIM ; Chul Hoon CHANG ; Soon Chan KWON ; Young Woo KIM ; Seung Hun SHEEN ; Sukh Que PARK ; Jun Kyeung KO ; Sung-kon HA ; Hae Woong JEONG ; Hyen Seung KANG ;
Journal of Cerebrovascular and Endovascular Neurosurgery 2024;26(1):13-22
Objective:
Endovascular coil embolization is the primary treatment modality for intracranial aneurysms. However, its long-term durability remains of concern, with a considerable proportion of cases requiring aneurysm reopening and retreatment. Therefore, establishing optimal follow-up imaging protocols is necessary to ensure a durable occlusion. This study aimed to develop guidelines for follow-up imaging strategies after endovascular treatment of intracranial aneurysms.
Methods:
A committee comprising members of the Korean Neuroendovascular Society and other relevant societies was formed. A literature review and analyses of the major published guidelines were conducted to gather evidence. A panel of 40 experts convened to achieve a consensus on the recommendations using the modified Delphi method.
Results:
The panel members reached the following consensus: 1. Schedule the initial follow-up imaging within 3-6 months of treatment. 2. Noninvasive imaging modalities, such as three-dimensional time-of-flight magnetic resonance angiography (MRA) or contrast-enhanced MRA, are alternatives to digital subtraction angiography (DSA) during the first follow-up. 3. Schedule mid-term follow-up imaging at 1, 2, 4, and 6 years after the initial treatment. 4. If noninvasive imaging reveals unstable changes in the treated aneurysms, DSA should be considered. 5. Consider late-term follow-up imaging every 3–5 years for lifelong monitoring of patients with unstable changes or at high risk of recurrence.
Conclusions
The guidelines aim to provide physicians with the information to make informed decisions and provide patients with high-quality care. However, owing to a lack of specific recommendations and scientific data, these guidelines are based on expert consensus and should be considered in conjunction with individual patient characteristics and circumstances.
9.A Combined Case of Endobronchial Lipoma and Broncholithiasis.
Jin Young AN ; Sun Jung KWON ; Jung Eun LEE ; Pyl Sun JANG ; Hyen Mo KANG ; Yeon Sun LEE ; Sung Soo JUNG ; Jin Whan KIM ; Ju Ock KIM ; Seung Pyung LIM ; Sun Young KIM
Journal of Lung Cancer 2004;3(1):43-46
Endobronchial lipomas are rare lesions that usually obstruct a major bronchus and cause irreversible pulmonary damage distally. Herein, a case of an endobronchial lipoma combined with broncholithiasis, found 3 months after first noticing symptoms including dry cough, and voice change, successfully removed by surgical resection is reported
Bronchi
;
Cough
;
Lipoma*
;
Voice
10.Effects of Repeated Nicotine Treatment on the Changes in Glutamate Receptor Subunits Levels in Mesocorticolimbic Dopamine Areas.
Kuem Ju LEE ; Dong Hoon KIM ; Song Hyen CHOI ; You Chan SHIN ; Sang Ha PARK ; Bo Hyun MOON ; Seung Woo KANG ; Eujin CHO ; Sang Hyun CHOI ; Boe Gwun CHUN ; Min Soo LEE ; Kyung Ho SHIN
The Korean Journal of Physiology and Pharmacology 2007;11(4):139-144
Recent studies suggest that alterations in glutamate receptor subunit levels in mesocorticolimbic dopamine areas could account for neural adaptations in response to psychostimulant drugs. Although many drugs of abuse induce changes in ionotropic glutamate receptor subunits in mesocorticolimbic dopamine areas, the changes of ionotropic glutamate receptor subunits by repeated nicotine treatment in these areas are not known. To answer this question, we injected male Sprague-Dawley rats twice daily with nicotine (0.4 mg/kg) or saline (1 ml/kg) for 10 days. The immunoreactivity of NR1, GluR1, and GluR2 glutamate receptor subunits was examined 16~18 h after the last injection of saline or nicotine. Repeated nicotine treatment significantly increased NR1 levels in the ventral tegmental area (VTA). In addition, repeated nicotine treatment showed a tendency towards an increase in GluR1 levels in the VTA as well as in striatum. However, there was no significant change in glutamate receptor subunits in other areas including nucleus accumbens (NAc). These results demonstrate that repeated nicotine treatment increases NR1 levels in VTA similarly to other drugs of abuse, suggesting that elevated glutamate receptor subunits in the VTA, but not NAc may be involved in the excitation of mesocorticolimbic dopamine neurons by nicotine.
Dopamine*
;
Glutamic Acid*
;
Humans
;
Male
;
Neurons
;
Nicotine*
;
Nucleus Accumbens
;
Rats, Sprague-Dawley
;
Receptors, Glutamate*
;
Street Drugs
;
Ventral Tegmental Area